Childhood Kidney Diseases

Korean Society of Pediatric Nephrology (대한소아신장학회)
권호 표지
DOI QR코드

DOI QR Code

Acute Respiratory Distress Syndrome after Rotavirus Infection in a C1q Nephropathy Patient: A Case Report

  • Kim, Hye Jin (Department of Pediatrics, Seoul National University Children's Hospital) ;
  • Min, Jeesu (Department of Pediatrics, Seoul National University Children's Hospital) ;
  • Kim, Ji Hyun (Department of Pediatrics, Seoul National University Bundang Hospital) ;
  • Choi, Yu Hyeon (Department of Pediatrics,Anyang University Seoul Hospital) ;
  • Han, Mi Seon (Department of Pediatrics, Seoul Metropolitan Government-Seoul National University Boramae Medical Center) ;
  • Ha, Il-Soo (Department of Pediatrics, Seoul National University Children's Hospital) ;
  • Kang, Hee Gyung (Department of Pediatrics, Seoul National University Children's Hospital)
  • Received : 2021.09.01
  • Accepted : 2021.10.30
  • Published : 2021.12.31
Download PDF
⟨ Previous Next ⟩

Abstract

C1q nephropathy is a rare glomerulopathy that typically presents with nephrotic syndrome in children. Treatment with immunosuppressive agents renders patients vulnerable to infection and its complications. Gastroenteritis is common in children, and rotavirus is a leading cause. Extraintestinal manifestations of rotavirus have recently been reported; however, there is a paucity of cases exploring the involvement of a rotavirus on the respiratory system. Acute respiratory distress syndrome (ARDS) is a rapid onset respiratory failure characterized by noncardiogenic pulmonary edema and hypoxemia. Causes of ARDS include sepsis, pneumonia, pancreatitis, aspiration, and trauma. In this paper, we report a case of ARDS after rotavirus infection in a child with C1q nephropathy who had been treated with immunosuppressive agents.

Keywords

Acknowledgement

Patient consent: This study was approved by the institutional review board (IRB), and consent was obtained from the patient and her parent (IRB number H-2107-175-1236).

References

  1. Jennette JC, Hipp CG. C1q nephropathy: a distinct pathologic entity usually causing nephrotic syndrome. Am J Kidney Dis 1985;6:103-10. https://doi.org/10.1016/s0272-6386(85)80150-5
  2. Bishop RF, Davidson GP, Holmes IH, Ruck BJ. Virus particles in epithelial cells of duodenal mucosa from children with acute non-bacterial gastroenteritis. Lancet 1973;2:1281-3.
  3. Lynch M, Shieh WJ, Tatti K, Gentsch JR, Harris TF, Jiang B, et al. The Pathology of Rotavirus-Associated Deaths, Using New Molecular Diagnostics. Clinical Infectious Diseases 2003;37:1327-33. https://doi.org/10.1086/379322
  4. Group PALICC. Pediatric acute respiratory distress syndrome: consensus recommendations from the Pediatric Acute Lung Injury Consensus Conference. Pediatric Critical Care Medicine. 2015;16:428-39. https://doi.org/10.1097/PCC.0000000000000350
  5. Tai IC, Huang YC, Lien RI, Huang CG, Tsao KC, Lin TY. Clinical manifestations of a cluster of rotavirus infection in young infants hospitalized in neonatal care units. Journal of Microbiology, Immunology and Infection 2012;45:15-21. https://doi.org/10.1016/j.jmii.2011.09.023
  6. Sasek L, Pazdiora P, Kobr J, Pizingerova K. Lethal course of rotavirus gastroenteritis-a case history. Klinicka Mikrobiologie a Infekcni Lekarstvi 2005;11:67-9.
  7. Blutt SE, Matson DO, Crawford SE, Staat MA, Azimi P, Bennett BL, et al. Rotavirus Antigenemia in Children Is Associated with Viremia. PLOS Medicine 2007;4:e121. https://doi.org/10.1371/journal.pmed.0040121
  8. Gilger MA, Matson DO, Conner ME, Rosenblatt HM, Finegold MJ, Estes MK. Extraintestinal rotavirus infections in children with immunodeficiency. J Pediatr 1992;120:912-7. https://doi.org/10.1016/S0022-3476(05)81959-6
  9. Zhaori G, Fu L, Xu Y, Guo Y, Peng Z, Shan W. Detection of rotavirus antigen in tracheal aspirates of infants and children with pneumonia. Chinese Medical Journal 1991;104:830-3.
  10. Santosham M, Yolken RH, Quiroz E, Dillman L, Oro G, Reeves WC, et al. Detection of rotavirus in respiratory secretions of children with pneumonia. The Journal of Pediatrics 1983;103:583-5. https://doi.org/10.1016/S0022-3476(83)80591-5
  11. Lewis HM, Parry JV, Davies HA, Parry RP, Mott A, Dourmashkin RR, et al. A year's experience of the rotavirus syndrome and its association with respiratory illness. Arch Dis Child 1979;54:339-46. https://doi.org/10.1136/adc.54.5.339
  12. Goldwater PN, Chrystie IL, Banatvala J. Rotaviruses and the respiratory tract. British Medical Journal 1979;2:1551. https://doi.org/10.1136/bmj.2.6204.1551
  13. Saulsbury FT, Winkelstein JA, Yolken RH. Chronic rotavirus infection in immunodeficiency. The Journal of Pediatrics 1980;97:61-5. https://doi.org/10.1016/s0022-3476(80)80131-4
  14. Blutt SE, Kirkwood CD, Parreno V, Warfield KL, Ciarlet M, Estes MK, et al. Rotavirus antigenaemia and viraemia: a common event? The lancet 2003;362:1445-9. https://doi.org/10.1016/S0140-6736(03)14687-9
  15. Dhokarh R, Li G, Schmickl CN, Kashyap R, Assudani J, Limper AH, et al. Drug-associated acute lung injury: a population-based cohort study. Chest 2012;142:845-50. https://doi.org/10.1378/chest.11-2103