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http://dx.doi.org/10.12701/yujm.2018.35.2.187

Risk factors for respiratory distress syndrome in full-term neonates  

Kim, Jin Hyeon (Department of Pediatrics, Yeungnam University College of Medicine)
Lee, Sang Min (Department of Pediatrics, Yeungnam University College of Medicine)
Lee, Young Hwan (Department of Pediatrics, Yeungnam University College of Medicine)
Publication Information
Journal of Yeungnam Medical Science / v.35, no.2, 2018 , pp. 187-191 More about this Journal
Abstract
Background: Respiratory distress syndrome (RDS) is a one of the most common cause of respiratory morbidity and mortality in neonates. This study was conducted to investigate the risk factors for RDS in full-term neonates. Methods: We conducted this retrospective study using medical records. The study group included 80 full-term neonates diagnosed with RDS and hospitalized in the neonatal intensive care unit between January 2012 and December 2016, at Yeungnam University Hospital. We analyzed sex, gestational age, birth weight, delivery method, maternal age, number of pregnancy, history of abortion, and complication of pregnancy. The control group included 116 full-time neonates who were hospitalized with jaundice during the same period. Results: The incidence of full-term RDS was more common in males (odds ratio [OR], 3.288; 95% confidence interval [CI], 1.446-7.479), cesarean section (OR, 15.03; 95% CI, 6.381-35.423), multiparity (OR, 4.216; 95% CI, 1.568-11.335). The other factors rendered no significant results. Conclusion: The risk factors for RDS in full-tern neonates were identified as male sex, cesarean section, and multiparity. Further studies involving more institutions are needed to clarify the risk factors for RDS in full-term infants.
Keywords
Full-term; Neonatal respiratory distress syndrome; Risk factor;
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1 Hibbard JU, Wilkins I, Sun L, Gregory K, Haberman S, Hoffman M, et al. Respiratory morbidity in late preterm births. JAMA 2010;304:419-25.   DOI
2 Condo V, Cipriani S, Colnaghi M, Bellu R, Zanini R, Bulfoni C, et al. Neonatal respiratory distress syndrome: are risk factors the same in preterm and term infants? J Matern Fetal Neonatal Med 2017;30:1267-72.   DOI
3 Agrawal V, David RJ, Harris VJ. Classification of acute respiratory disorders of all newborns in a tertiary care center. J Natl Med Assoc 2003;95:585-95.
4 Edwards MO, Kotecha SJ, Kotecha S. Respiratory distress of the term newborn infant. Paediatr Respir Rev 2013;14:29-36.   DOI
5 Lee JM, Kim DK, Lee SJ. Probable prognostic factors among the revealing clinical manifestations at admission in neonates with tachypnea. J Korean Soc Neonatol 2006;13:32-9.
6 Liu J, Shi Y, Dong JY, Zheng T, Li JY, Lu LL, et al. Clinical characteristics, diagnosis and management of respiratory distress syndrome in full-term neonates. Chin Med J (Engl) 2010;123:2640-4.
7 Dani C, Reali MF, Bertini G, Wiechmann L, Spagnolo A, Tangucci M, et al. Risk factors for the development of respiratory distress syndrome and transient tachypnoea in newborn infants. Eur Respir J 1999;14:155-9.   DOI
8 Bresson E, Seaborn T, Cote M, Cormier G, Provost PR, Piedboeuf B, et al. Gene expression profile of androgen modulated genes in the murine fetal developing lung. Reprod Biol Endocrinol 2010;8:2.   DOI
9 Nielsen HC, Torday JS. Sex differences in avian embryo pulmonary surfactant production: evidence for sex chromosome involvement. Endocrinology 1985;117:31-7.   DOI
10 Seaborn T, Simard M, Provost PR, Piedboeuf B, Tremblay Y. Sex hormone metabolism in lung development and maturation. Trends Endocrinol Metab 2010;21:729-38.   DOI
11 Liu J, Yang N, Liu Y. High-risk factors of respiratory distress syndrome in term neonates: a retrospective case-control study. Balkan Med J 2014;31:64-8.
12 Nielsen HC. Androgen receptors influence the production of pulmonary surfactant in the testicular feminization mouse fetus. J Clin Invest 1985;76:177-81.   DOI
13 Hansen AK, Wisborg K, Uldbjerg N, Henriksen TB. Risk of respiratory morbidity in term infants delivered by elective caesarean section: cohort study. BMJ 2008;336:85-7.   DOI
14 Roth-Kleiner M, Wagner BP, Bachmann D, Pfenninger J. Respiratory distress syndrome in near-term babies after caesarean section. Swiss Med Wkly 2003;133:283-8.
15 Melamed N, Klinger G, Tenenbaum-Gavish K, Herscovici T, Linder N, Hod M, et al. Short-term neonatal outcome in lowrisk, spontaneous, singleton, late preterm deliveries. Obstet Gynecol 2009;114:253-60.   DOI
16 Altman M, Vanpée M, Cnattingius S, Norman M. Risk factors for acute respiratory morbidity in moderately preterm infants. Paediatr Perinat Epidemiol 2013;27:172-81.   DOI
17 Wiswell TE, Tuggle JM, Turner BS. Meconium aspiration syndrome: have we made a difference? Pediatrics 1990;85:715-21.
18 Perelman RH, Palta M, Kirby R, Farrell PM. Discordance between male and female deaths due to the respiratory distress syndrome. Pediatrics 1986;78:238-44.
19 Koivisto M, Marttila R, Kurkinen-Räty M, Saarela T, Pokela ML, Jouppila P, et al. Changing incidence and outcome of infants with respiratory distress syndrome in the 1990s: a population-based survey. Acta Paediatr 2004;93:177-84.   DOI