• Title/Summary/Keyword: carrier transport

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Diffusion Coefficients and Membrane Potential within Carrier Membrane by Reverse Transport System

  • Yang, Wong-Kang;Jeong, Sung-Hyun;Lee, Won-Chul
    • Korean Membrane Journal
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    • v.4 no.1
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    • pp.36-40
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    • 2002
  • The diffusion coefficients of ions in the reverse transport system using the carrier mediated membrane were estimated from the diffusional membrane permeabilities and the ion activity in membrane system. In the aqueous alkali metal ions-membrane system diffusional flux of alkali metal ions driven by coupled proton was analyzed. The aqueous phase I contained NaOH solution and the aqueous phase II also contained NaCl and HCl mixed solution. The concentration of Na ions of both phases were $10^{0},\;10^{-1},\;10^{-2},\;5{\times}10^{-1}\;and\;5{\times}10^{-2}\;mol{\cdot}dm^{-3}$ and the concentration of HCI in aqueous phase II was always kept at $1{\times}10^{-1}\;mol{\cdot}dm^{-3}$. Moreover, the carrier concentration in liquid membrane was $10^{-2}\;mol{\cdot}dm^{-3}$. The results indicated that the diffusion coefficients depend strongly on the concentration of both phases electrolyte solution equilibriated with the membrane. The points were interpreted in terms of the energy barrier theory. Furthermore, eliminating the potential terms from the membrane equation was derived.

Imperatorin is Transported through Blood-Brain Barrier by Carrier-Mediated Transporters

  • Tun, Temdara;Kang, Young-Sook
    • Biomolecules & Therapeutics
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    • v.25 no.4
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    • pp.441-451
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    • 2017
  • Imperatorin, a major bioactive furanocoumarin with multifunctions, can be used for treating neurodegenerative diseases. In this study, we investigated the characteristics of imperatorin transport in the brain. Experiments of the present study were designed to study imperatorin transport across the blood-brain barrier both in vivo and in vitro. In vivo study was performed in rats using single intravenous injection and in situ carotid artery perfusion technique. Conditionally immortalized rat brain capillary endothelial cells were as an in vitro model of blood-brain barrier to examine the transport mechanism of imperatorin. Brain distribution volume of imperatorin was about 6 fold greater than that of sucrose, suggesting that the transport of imperatorin was through the blood-brain barrier in physiological state. Both in vivo and in vitro imperatorin transport studies demonstrated that imperatorin could be transported in a concentration-dependent manner with high affinity. Imperatorin uptake was dependent on proton gradient in an opposite direction. It was significantly reduced by pretreatment with sodium azide. However, its uptake was not inhibited by replacing extracellular sodium with potassium or N-methylglucamine. The uptake of imperatorin was inhibited by various cationic compounds, but not inhibited by TEA, choline and organic anion substances. Transfection of plasma membrane monoamine transporter, organic cation transporter 2 and organic cation/carnitine transporter 2/1 siRNA failed to alter imperatorin transport in brain capillary endothelial cells. Especially, tramadol, clonidine and pyrilamine inhibited the uptake of [$^3H$]imperatorin competitively. Therefore, imperatorin is actively transported from blood to brain across the blood-brain barrier by passive and carrier-mediated transporter.

The Study of Luminescence Efficiency by change of OLED's Hole Transport Layer

  • Lee, Jung-Ho
    • International Journal of Precision Engineering and Manufacturing
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    • v.7 no.2
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    • pp.52-55
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    • 2006
  • The OLEDs(Organic Light-Emitting Diodes) structure organizes the bottom layer using glass, ITO(indium thin oxide), hole injection layer, hole transport layer, emitting material layer, electron transport layer, electron injection layer and cathode using metal. OLED has various advantages. OLEDs research has been divided into structural side and emitting material side. The amount of emitting light and luminescence efficiency has been improved by continuing effort for emitting material layer. The emitting light mechanism of OLEDs consists of electrons and holes injected from cathode and anode recombination in emitting material layer. The mobilities of injected electrons and holes are different. The mobility of holes is faster than that of electrons. In order to get high luminescence efficiency by recombine electrons and holes, the balance of their mobility must be set. The more complex thin film structure of OLED becomes, the more understanding about physical phenomenon in each interface is needed. This paper observed what the thickness change of hole transport layer has an affection through the below experiments. Moreover, this paper uses numerical analysis about carrier transport layer thickness change on the basis of these experimental results that agree with simulation results.

A Study on the Liability Principle of the Multimodal Transporter (복합운송인(複合運送人)의 책임원칙(責任原則) - UN복합운송조약(複合運送條約)과 UNCTAD/ICC통일규칙(統一規則)을 중심(中心)으로 -)

  • Song, Chae-Hun
    • THE INTERNATIONAL COMMERCE & LAW REVIEW
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    • v.13
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    • pp.303-328
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    • 2000
  • International Trade has led to the increase of the demand of international transport, and also the development of transport vehicles has been promoting the volumes of international trade. Therefore, the development of international transport not only incurs claims concerning transportation but also establishes various international rules to settle the claims between the shippers and the carriers in the course of transport. With a view to settling the claims successfully, the men who are concerned in the transport have to know the principle and scope of carrier's Liability. In this paper, I would like to find out the principle of Liability for the shippers. Therefore, I classify the Liability principle of the international transporter under the UNs Convention on International Multimodal Transport of Good(1980) and UNCTDAD/ICC Rules(1991) in three system - Network Liability System, Uniform Liability System and Modified Uniform Liability System.

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IN VIVO INVESTIGATION ON THE INTESTINAL ABSORPTION OF VITAMIN A-ALCOHOL (RETINOL) IN RATS

  • Whang, Eun-Mi;Burger, Hans-Jurgen
    • Proceedings of the Korean Nutrition Society Conference
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    • 1995.05c
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    • pp.21-21
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    • 1995
  • Absorption of fat-soluble vi tamin, retinol occurs mainly in the proximal part of small intestine. But its intestinal transport mechanism isn't yet clear. The aim of the present study was to investigate on the mechanism of absorption of retinol by determining a concentration-dependent kinetic of retinol absorption in rats. The study was carried out by applying in vivo technique in which vitamin solution was infused to intestinal lumen and at the same time thoracic duct and choledochus duct were canulated to collect samples. The investigations showed that retinol is absorbed in the small intestine by a saturable, carrier-mediated transport system, i.e. wi thout signi ficant differences between the proximal and distal halves of the small intestine. The transport of retinol taken up by the enterocytes occured via different mechanisms: while the main vitamin A transport via the thoracic duct was saturated by limiting transport factors such as retinol-CRBP-II-complex formation and retinol esterification with increasing substrate concentrations, the transport of retinol metabolite product via the portal vein was proportional to the substrate concentration.ration.

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Selective Transport of Lead(II) through a Bulk Liquid Membrane Using a Cooperative Carrier Composed of Benzylaza-12-crown-4 and Oleic Acid

  • Kazemi, Sayed Yahya;Shamsipur, Mojtaba
    • Bulletin of the Korean Chemical Society
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    • v.26 no.6
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    • pp.930-934
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    • 2005
  • A chloroform membrane system containing a given mixture of benzylaza-12-crown-4 and oleic acid is introduced for the selective and efficient transport of $Pb^{2+}$ ion. The transport was capable of moving metal ions ‘up-hill’. In the presence of ${S_2O_3}^{2-}$ion as a suitable metal ion acceptor in the receiving phase, the amount of lead ion transport across the liquid membrane after 150 minutes is (95.0 ${\pm}$ 1.7)%. The selectivity and efficiency of lead transport from aqueous solution containing $Tl^+,\;Ag^+,\;Mg^{2+},\;Ca^{2+},\;Co^{2+},$ $Ni^{2+},\;Cu^{2+},\;Zn^{2+},\;Hg^{2+}$ and $Cd^{2+}$were investigated. In the presence of thiosulfate as a suitable masking agent in the source phase, the interfering effects of $Ag^+\;and\;Cu^{2+}$ were diminished drastically.

Specific Inhibition of Polar Auxin Transport by n-Octanol in Maize Coleoptiles (옥수수(Zea mays L.) 자엽초 조직 절편에서 n-Octanol에 의한 옥신 극성 이동 억제)

  • 윤인선
    • Journal of Plant Biology
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    • v.36 no.1
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    • pp.67-74
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    • 1993
  • Both polar and gravity-induced lateral transport of auxin was markedly reduced in corn coleoptile segments by octanol treatment. Octanol enhance net auxin uptake without affecting that of benzoic acid, suggesting that the effect did not result from a nonspecific action on general membrane permeability. Since naphthylphthalamic acid (NPA) action on both transport and net uptake of auxin was substantially decreased in the presence of octanol, a specific interaction of octanol with the NPA site (efflux carrier) can be postulated. Studies on in vitro binding of NPA to membrane vesicles indicated that octanol did not interfere with NPA binding. When basipetal transport of auxin was impared by plasmolysis, octanol still inhibited auxin transport in the plasmolyzed tissues. The results ruled out the possibility of octanol acting at the plasmodesmata. Kinetic analysis of growth indicated that IAA-sustained growth was rapidly blocked by octanol implicating a common system by which auxin transport is linked to auxin action. Possible mechanisms for octanol action will be discussed.

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Enhancing the Efficiency of Core/Shell Nanowire with Cu-Doped CdSe Quantum Dots Arrays as Electron Transport Layer (구리 이온 도핑된 카드뮴 셀레나이드 양자점 전자수송층을 갖는 나노와이어 광전변환소자의 효율 평가)

  • Lee, Jonghwan;Hwang, Sung Won
    • Journal of the Semiconductor & Display Technology
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    • v.19 no.4
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    • pp.94-98
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    • 2020
  • The core/shell of nanowires (NWs) with Cu-doped CdSe quantum dots were fabricated as an electron transport layer (ETL) for perovskite solar cells, based on ZnO/TiO2 arrays. We presented CdSe with Cu2+ dopants that were synthesized by a colloidal process. An improvement of the recombination barrier, due to shell supplementation with Cu-doped CdSe quantum dots. The enhanced cell steady state was attributable to TiO2 with Cu-doped CdSe QD supplementation. The mechanism of the recombination and electron transport in the perovskite solar cells becoming the basis of ZnO/TiO2 arrays was investigated to represent the merit of core/shell as an electron transport layer in effective devices.

Recent Progress in Flexible Perovskite Solar Cell Development

  • Ren, Xiaodong;Jung, Hyun Suk
    • Journal of the Korean Ceramic Society
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    • v.55 no.4
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    • pp.325-336
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    • 2018
  • Perovskite solar cells (PSCs) are a new class of photovoltaic devices, which have attracted significant attention due to their remarkable optoelectrical properties, including high absorption coefficients, high carrier mobilities, long carrier diffusion lengths, tunable bandgaps, low cost, and facile fabrication. PSCs have reached efficiencies of 22.70% and 18.36% on rigid fluorine-doped tin oxide and poly(ethylene terephthalate) substrates, respectively; these are comparable to those of single-crystal silicon and copper-indium-gallium-selenium solar cells. Over the past eight years, the photo conversion efficiency of PSCs has been significantly improved by device-architecture adjustments, and absorber and electron/hole transport layer optimization. Each layer is important for the performance of PSCs; hence, we discuss achievements in flexible perovskite solar cells (FPSCs), covering electron/hole-transport materials, electrode materials. We give a comprehensive overview of FPSCs and put forward suggestions for their further development.

Effect of Dopping Conditions on a-Se Thin-Films : Microstructural and I-V Study (비정질 박막에 대한 도핑 조건의 영향 및 미세구조와 I-V 연구)

  • 박성광;박지군;강상식;공현기;김진섭;남상희
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2001.11a
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    • pp.492-496
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    • 2001
  • Due to their better photosensitivity in X-ray, the amorphous selenium based photoreceptor is widely used on the X-ray conversion materials. It was possible to control the charge carrier transport of amorphous selenium by suitably alloying a-Se with other elements(e,g. As, Cl). In this paper, We investigated dopants(As, Cl) composition rate to improve dark resistivity and transport properties of charge carrier in amorphous selenium using by direct X-ray conversion material. Alloying a-Se with As inhibits the recrystallization of a-Se but introduces undesirable deep hole traps. then doping with Cl(in the ppm range) compensates for the deep hole traps. We investigated their composition rate in various doping conditions and then obtained optimum dopant composition rate. The result was Se-As 0.3%-Cl 30 ppm and X-ray Sensitivity was 0.57 pc/pixel$.$mR at 137 $\mu\textrm{m}$ x 137 $\mu\textrm{m}$ Pixel area.

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