• Asian Pacific Journal of Cancer Prevention
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• v.13 no.5
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• pp.2063-2068
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• 2012

Aim: Liquid-based cytology is the most often used method for cervical cancer screening, but it is relatively insensitive and frequently gives equivocal results. Used as a complementary procedure, the high-risk human papillomavirus (HPV) DNA test is highly sensitive but not very specific. The human telomerase RNA gene (TERC) is the most often amplified oncogene that is observed in cervical precancerous lesions. We assessed genomic amplification of TERC in liquid-based cytological specimens to explore the optimal strategy of using this for cervical cancer screening. Methods: Six hundred and seventy-one residual cytological specimens were obtained from outpatients aged 25 to 64 years. The specimens were evaluated by the Digene Hybrid Capture 2 (HC2) HPV DNA test and fluorescence in situ hybridization (FISH) with a chromosome probe to TERC (3q26). Colposcopic examination and histological evaluation were performed where indicated. Results: The TERC positive rate was higher in the CIN2+ (CIN2, CIN3 and SCC) group than in the normal and CIN 1 groups (90.0% vs. 10.4%, p < 0.01). In comparison with the HC2 HPV DNA test, the TERC amplification test had lower sensitivity but higher specificity (90.0% vs. 100.0%, 89.6% vs. 44.0%, respectively). TERC amplification test used in conjunction with the HC2 HPV DNA test showed a combination of 90.0% sensitivity and 92.2% specificity. Conclusion: The TERC amplification test can be used to diagnose cervical precancerous lesions. TERC and HPV DNA co-testing shows an optimal combination of sensitivity and specificity for cervical cancer screening.

• Journal of the Institute of Electronics and Information Engineers
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• v.52 no.6
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• pp.117-125
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• 2015

In the modern age, it is important for people to maintain a good sitting posture because they spend long hours sitting. Posture correction treatment requires a great deal of time and expenses with continuous observation by a specialist. Therefore, there is a need for a system with which users can judge and correct their postures on their own. In this study, we collected users' postures and judged whether they are normal or abnormal. To obtain a user's posture, we propose a four-joint motion capture system that uses inertial sensors. The system collects the subject's postures, and features are extracted from the collected data to build a database. The data in the DB are classified into normal and abnormal postures after posture learning using the K-means clustering algorithm. An experiment was performed to classify the posture from the joints' rotation angles and positions; the normal posture judgment reached a success rate of 99.79%. This result suggests that the features of the four joints can be used to judge and help correct a user's posture through application to a spinal disease prevention system in the future.

• Geomechanics and Engineering
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• v.30 no.2
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• pp.211-218
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• 2022

This study characterizes Proctor and geophysical properties in a broad range of grading and fines contents. The results show that soil index properties such as uniformity and fines plasticity control the optimum water content and peak dry unit trends, as well as elastic wave velocity. The capillary pressure at a degree of saturation less than S = 20% plays a critical role in determining the shear wave velocity for poorly graded sandy soils. The reduction in electrical resistivity with a higher water content becomes pronounced as the water phase is connected A parallel set of compaction and geophysical properties of sand-kaolinite mixtures reveal that the threshold boundaries computed from soil index properties adequately capture the transitions from sand-controlled to kaolinite-controlled behavior. In the transitional fines fraction zone between F_F ≈ 20 and 40%, either sand or kaolinite or both sand and kaolinite could dominate the geophysical properties and all other properties associated with soil compaction behavior. Overall, the compaction and geophysical data gathered in this study can be used to gain a first-order approximation of the degree of compaction in the field and produce degree of compaction maps as a function of water content and fines fraction.

• Korean Journal of Veterinary Service
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• v.42 no.1
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• pp.9-15
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• 2019

Transmissible gastroenteritis (TGE) is a disease confined to pigs of all ages, and can be a significant cause of economic loss in breeding herds, primarily because of the very high piglet mortality. The causative agent is a coronavirus, an enveloped positive strand RNA virus and closely related but non-enteropathogenic porcine respiratory coronavirus (PRCV). Although the TGEV has declined with its innocent relative, PRCV, further genome changes could not be excluded. Therefore, the herd-level immunity against this virus is important for the prevention of disease and should be carefully monitored. The aim of this study is to develop monoclonal antibody capture enzyme-linked immunosorbent assay (MAC-ELISA) which can rapidly and accurately determine a large numbers of serum samples for surveillance purpose, and to compare the ELISA with a TGEV-specific serum neutralization test. The MAC-ELISA was sufficiently achieved, and the comparison with the virus-specific serum neutralization assays for 713 sera from pig farms showed a high correlation ($r^2=0.812$, P<0.001). The specificity and sensitivity of MAC-ELISA for the serum neutralization test 91.9% and 91.6%, respectively, which means that the antibody detected by the MAC-ELISA could be said to be protective antibodies. In conclusion, the developed MAC-ELISA would be very helpful in evaluating protective antibodies against TGEV.

• Journal of Broadcast Engineering
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• v.26 no.1
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• pp.88-98
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• 2021

Recently, the crime prevention and culprit identification even in a low illuminated environment by CCTV is becoming ever more important. In a low lighting situation, CCTV applications capture images under infrared lighting since it is unobtrusive to human eye. Although the infrared lighting leads to advantage of capturing an image with abundant fine texture information, it is hard to capture the color information which is very essential in identifying certain objects or persons in CCTV images. In this paper, we propose a method to acquire color information through DCGAN from an image captured by CCTV in a low lighting environment with infrared lighting and a method to remove color noise in the acquired color image.

• Journal of the Korean Geographical Society
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• v.47 no.3
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• pp.426-439
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• 2012

The goal of this study is to propose a new method to capture the qualitative person spatial behavior. Beyond tracking or indexing the change of the location of a person, the changes in the relationships between a person and its environment are considered as the main source for the formal model of this study. Specifically, this paper focuses on the movement behavior of a person near the boundary of a region. To capture the behavior of person near the boundary of regions, a new formal approach for integrating an object's scope of influence is described. Such an object, a spatio-temporally extended point (STEP), is considered here by addressing its scope of influence as potential events or interactions area in conjunction with its location. The formalism presented is based on a topological data model and introduces a 12-intersection model to represent the topological relations between a region and the STEP in 2-dimensional space. From the perspective of STEP concept, a prototype analysis results are provided by using GPS tracking data in real world.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.1
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• pp.91-96
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• 2012

Objectives: To determine the prevalence of HPV and cervical neoplasia among HIV-infected women in southwestern China. Methods: Cervical cytology, HPV detection by Hybrid Capture-$2^{TM}$ assay, and diagnostic colposcopy were followed by cervical biopsy if indicated. Logistic regression analysis was used to analyze associations between HPV co-infection and cervical intraepithelial neoplasia (CIN), and HIV-related clinical and laboratory parameters. Results: Colposcopic-histopathologically proven CIN2+ lesions were present in 7/83 (8.4%) HIV-infected women. Nearly half (41/83, 43%) were co-infected with carcinogenic HPV genotypes. HPV co-infection was higher in women with colposcopic-histopathologically proven CIN2+ lesions than women with $cells/{\mu}L$ had higher CIN2+ prevalence after adjusting for current ART status and age (adjusted OR: 6.3, 95% CI: 1.1, 36.5). Conclusions: HIV/AIDS care and treatment programs should integrate effective cervical cancer prevention services to mitigate the risk of invasive cervical cancer among HIV-infected women in China.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2005.06a
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• pp.1925-1928
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• 2005

In recent years, the importance of the characterization of fall for a fracture prevention system keeps increasing since fracture from a fall can lead to serious health problems. Fall is one of the major sources which increase morbidity in elderly people. In terms of the cost and the influence to the quality of life, the most serious injury with hip fractures is caused by falls. The traditional methods in characterizing fall patterns have been mainly by the epidemiological surveys. With surveys, the exact data of fall patterns can not been acquired. In this paper, we measured and analyzed with the parameters related to fall pattern such as velocities and accelerations during the motion of falls using 3D motion capture program. We acquired the parameters of the fall pattern of intentional and unexpected fall. The result showed that the variation of velocity and acceleration during fall was very important in characterizing fall pattern, which of vital importance for the development of a fracture prevention system and for the safety of the elderly

• Proceedings of the IEEK Conference
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• 1999.06a
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• pp.1063-1066
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• 1999

The delay of cardiac depolarization wave detection in the conventional pacemakers or AICD (automatic implantable cardioverter/ defibrillator, or ICD) has been overlooked. However, it is known that the delay may cause hemodynamic problems and may prevent the proper operation of a new automatic feature, automatic capture verification, that is to be appeared in the near-future devices. In order to reduce the effects of the delay, a delay prevention algorithm was developed and tested by applying three human electrograms. The algorithm set the sensing threshold just above the measured noise level to reduce the detection delay. It is found that the low threshold was able to reduce the delay by 20msec(average) In most cases. The implementation results showed reliability and efficacy of the algorithm, and the algorithm could be applicable to the existing hardware and software of the conventional pacemakers and AICD without any significant modifications.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.2
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• pp.891-894
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• 2014

This study is aimed to investigate the role of paired boxed gene 1 (PAX1) methylation analysis by methylation-sensitive high-resolution melting (MS-HRM) in the detection of high grade lesions in atypical squamous cells cannot exclude high-grade squamous intraepithelial lesion (ASC-H) and compared its performance with the Hybrid Capture 2 (HC2) human papillomavirus (HPV) test. In our study, 130 cases with a diagnosis of ASC-H from the cervical cytological screening by Thinprep cytologic test (TCT) technique were selected for triage. Their cervical scrapings were collected and evaluated by using PAX1 methylation analysis (MS-HRM) and high-risk HPV DNA test (HC2), followed by colposcopy and cervical biopsy. Chi-square test were used to test the differences of PAX1 methylation or HPV infection between groups. In the detection of CIN2+, the sensitivity, specificity, the PPV, NPV and the accuracy of PAX1 MS-HRM assay and high-risk HPV (HR-HPV) tests were respectively 80.6% vs 67.7%, 94.9% vs 54.5%, 83.3%, vs 31.8%, 94.0% vs 84.4%, and 91.5% vs 57.7%. The PAX1 MS-HRM assay proved superior to HR-HPV testing in the detection of high grade lesions (CIN2+) in ASC-H. This approach could screen out the majority of high grade lesion cases of ASC-H, and thus could reduce the referral rate to colposcopy.