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Preliminary Studies on the Necropsy-Based Health Assessment Index (HAI) Using a Ecological Indicator Species (생태 지표종을 이용한 해부학적 건강성 평가지수(HAI) 적용을 위한 예비실험)

  • Kim, Ja-Hyun;Bae, Dae-Yeul;Lee, Jae-Yon;An, Kwang-Guk
    • Korean Journal of Ecology and Environment
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    • v.39 no.1 s.115
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    • pp.62-72
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    • 2006
  • Biological health in aquatic environments has been assessed by several approaches using various bio-taxa. Especially, fish has been identified as one of the best ecological indicators for an integrative health assessments in aquatic environments. In this preliminary study, the necropsy-based approach using the Health Assessment Index (Adams et al., 1993; HAI, Blazer, 2000), was employed for the assessments of aquatic environments influenced by effluent water from wastewater disposal plants (WDP) near a urban stream (i.e., Cap-Stream). For the impact analysis from the effluents, we developed 10 metric necropsy-based model including $M_l\;skin,\;M_2\;fin,\;M_3\;thymus,\;M_4\;spleen,\;M_5\;hindgut,\;M_6\;kidney,\;M_7\;liver.\;M_8\;eyes,\;M_9\;gill,\;and\;M_{10}$ pseudobranch. We set up duplicate controls (natural upstream water plus 5 fishes in each control tank) and duplicate treatments (effluent water from the WDP plus 5 fishes in each treatment tank) in the laboratory. Preliminary results showed that HAI values in the controls were zero, indicating an excellent condition by the criteria of HAI, while the HAI values in the treatments ranged between 40 and 150, indicating a poor condition. Also, various health conditions, based on the index of biological integrity (IBI), species richness, tolerance guilds, and trophic guilds supported the HAI approach. The HAI approach, not applied in Korea, not may be used as an surrogate fer ecological health assessment in lotic ecosystems.

Determination of Phantom Scatter Factors for Small Photon Fields (소조사면 광자선의 팬톰산란인수 결정)

  • Oh, Young-Kee;Choi, Tae-Jin;Kim, Jin-Hee;Kim, Ok-Bae
    • Progress in Medical Physics
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    • v.20 no.2
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    • pp.106-111
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    • 2009
  • Total scatter factor ($S_{cp}$), head scatter factor ($S_c$) and phantom scatter factor ($S_p$) are very important for accurate radiation therapy at stereotactic radiosurgery (SRS) with irregular field shape using micro-MLC and intensity modulated radiation therapy (IMRT) including many small field sizes. In this study we measured and compared $S_{cp}$ with reference ion chamber, pinpoint chamber and diode detector and adapted the resuls form diode detector. Head scatter factors for small field sizes were also measured with diode detector covered 1.5 cm-thick solid water build-up cap. Some errors like as electron contamination of 1~3% were included in the values of Sc but trend of total results of $S_c$ was coincided with basic theory. Phantom scatter factors for small field sizes were calculated form $S_{cp}$ and $S_c$. The results of $S_p$ were compared and were well-agreed with those of other authors.

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Cloning of the posterior silk glands specific-expressed gene of silkworm (누에 후부실샘 특이 발현 유전자 클로닝)

  • Piao, Yulan;Kim, Seong-Ryul;Kim, Sung-Wan;Kang, Seok-Woo;Goo, Tae-Won;Choi, Kwang-Ho
    • Journal of Sericultural and Entomological Science
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    • v.53 no.1
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    • pp.44-49
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    • 2015
  • We characterized tissue specific-expressed genes in the posterior silk gland of Bombyx mori using by the Annealing Control Primer based differential display-PCR manner. In this study, we isolated 34 differentially expressed PCR amplicons, which one of these was identified as a novel transcript named as ACP-16 (366 bp), its expression was observed only in the posterior silk glands by Northern blot analysis. To determine promoter region of the ACP-16, we isolated and analyzed a phage DNA having 1.7 kb-long genome DNA including the open reading flame and 5'- upstream untranslated region of the ACP-16 gene from a genomic DNA library. We have estimated a promoter region of the ACP-16 gene by a web promoter prediction engine, which locates -750 ~ -165 from translation initiation site (ATG, +1). ACP-16 gene is necessary to more studies about critical biological role in order to apply the silkworm's transgenic system.

Adjustment Factor for Heavy Vehicles in Estimating Capacity at Unsignalized Intersections (비신호 교차로의 중차량 용량 보정계수에 관한 연구)

  • 이용재;김석근
    • Journal of Korean Society of Transportation
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    • v.19 no.2
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    • pp.89-98
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    • 2001
  • The objective of this Paper is to derive an adjustment factor for the presence of heavy vehicles when estimating capacity at unsignalized intersections (and/or at modern roundabouts). According to the 1997 and 2000 Highway Capacity Manual (HCM), potential capacity in such cases is estimated by simply adjusting base critical gap and base follow-up time. However, the procedure suggested in the HCM may lead to some errors in the adjustment, hence resulting in poor evaluation and design for the intersections, because it determines the value of adjusting factors by only the number of lanes on main streets regardless of the types of heavy vehicles. This paper shows a simple formula for making the adjustment. This formula is much like the HCM formula used for heavy vehicles in estimating highway capacity by the adoption of passenger car units (PCU). In contrast to the traditional approaches seen in the HCM, the PCU value of this case is explicitly expressed by the flow rate in the major streams and the gap difference in critical gaps chosen by passenger cars and particular heavy vehicles. Computational results of the adjustment factor are graphically illustrated.

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Geomorphological Approach in Geological Mapping of the Miocene and Post-Miocene Formations in the Albudeite Area, Spain (동남(東南) Spain Albudeite 지역(地域)의 Miocene및 Post-Miocene Formation에 대한 지질조사(地質調査)에 있어서의 지형학적(地形學的)인 접근(接近))

  • Yun, Suckew
    • Economic and Environmental Geology
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    • v.6 no.3
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    • pp.171-182
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    • 1973
  • Gemorphological and photogeological techniqes are applied to the problem of geological mapping of a semi-arid area, Albudeite, Southeastern Spain. As a result of this, a geological and surface materials map is made which shows the upper Miocene formation, which mainly consists of marl, limestone and sandstone, is further subdivided into three members, i. e. lower, middle and upper, and the post-Miocene deposits were differentiated into seven stratigraphic units, and mapped. The relationships between geology, landforms and land comlexes previously reognized have been reviewed. The methods adopted have proved to be valuable in interpreting and mapping a compex relationship in which highly variable bedrock outcrops and shallow surface materiales produced under sub-aerial conditios.

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Considerations on the Safety of Electric Caps Based on Measured Electrical Resistivity of Rock Samples (암석의 전기비저항 측정을 통한 전기뇌관의 사용 안전성 검토)

  • Choi, Byung-Hee;Ryu, Chang-Ha;Shin, Seung-Wook;Kim, Soo-Lo
    • Explosives and Blasting
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    • v.34 no.4
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    • pp.19-27
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    • 2016
  • Much care should be taken when electric caps are used in blast site than when non-electric initiation systems are used. This is because electric caps can cause premature firing or misfires if stray currents of high magnitude flow into the blasting circuit. If the rock has higher electrical conductivity or lower electrical resistivity, such risks will be increased because the rock will provide more passages for the stray currents to flow into the blasting circuit. In this study, several rock samples obtained at a blast site were tested for electrical resistivity to decide whether electric caps could be used or not in the site. The measured electrical resistivity was $39{\sim}47{\Omega}{\cdot}m$ for the rock samples that had a higher content of metal sulfides. Contrary, the resistivity was $15000{\sim}21000{\Omega}{\cdot}m$ for ordinary rocks. Especially, in the case of the rock of electric resistivity of $39{\Omega}{\cdot}m$, only 2-V electric potential enables a stray current to flow through the rock of 1-m length, which can cause the premature firing of a detonator whose initiation current is 0.4 A. This result shows that electric initiation system should not be used in the site because rocks containing much amount of metal sulfides are widely distributed there.

CLIMATOLOGICAL CHARACTERISTICS OF THE POLAR IONOSPHERE BASED ON THE SONDRESTROM INCOHERENT SCATTER RADAR MEASUREMENTS (SONDRESTROM 비간섭 산란 레이더 자료를 이용한 극지방 전리층의 기후학적 특성 연구)

  • 곽영실;안병호
    • Journal of Astronomy and Space Sciences
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    • v.19 no.1
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    • pp.75-88
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    • 2002
  • The climatological characteristics of the polar ionosphere is examined in terms of the ionospheric conductance and electric field. For this purpose, 109 days of measurements from the Sondrestrom incoherent scatter radar are utilized. By combining these two quantities, it is possible to deduce the overhead ionospheric current distributions. The ionospheric current density thus obtained is compared with the corresponding ground magnetic disturbance. Also examined is the effect of the field-aligned current on the ground magnetic disturbance, particularly on the D component Several interesting climatological characteristics about the ionosphere over the Sonderstrom are apparent from this study. (1) The conductance distribution is mainly due to solar EUV radiation during day-time On the other hand, the conductance distribution during the night-time is very low. (2) The conductance distribution one. the polar cap region during the day-time is controlled mostly by the solar EUV radiation, while it is extremely low during night-time wish the Hall and Pedersen conductances being 1.6 and 1.2 siemen, respectively (3) The region of the maximum N-S electric field tend to locate in the dayside sector. The E-W component of the electric field is stronger than that over Chatanika (4) The E-W auroal inospheric current (J/sub E/) is more important in the sunlit hemisphere than the night hemisphere. And a strong southward current is noted in the prenoon sector (5) There is a significant correlation between the overhead ionospheric current and the simultaneously observed ground magnetic disturbance. However, the assumption for the infinite sheet current approximation is far from realistic, underestimating the current density. And the correlation between ${\Delta}H$ and J/sub E/ is higher than the one between ${\Delta}D$ and J/sub N/ , indicating that field-aligned current affects significantly ${\Delta}D$.

The Comorbidity of Attention Deficit Hyperactivity Disorder and the Effect of Methylphenidate on it (주의력 결핍 과잉 운동 장애 환자들의 약물치료 효과 및 Comorbidity에 관한 연구)

  • Lee, Jong-Bum;Park, Hyung-Bae
    • Journal of Yeungnam Medical Science
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    • v.10 no.1
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    • pp.166-178
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    • 1993
  • The objectives of this study were to evaluate the effect of methylphenidate on attention deficit hyperactivity disorder (ADHD) and the comorbidity of the disorder, using child attention problem checklist to 56 (male: 38, female: 18) patients from, March 992 to February 1993. The results were as follows: Among 56 subjects, ADHD alone were 20 (335.71%) subjects, and with one additional diagnosis were 31 (55.35%) subjects and with two additional diagnosis were 5 (8.93%) subjects. There was significant improvement on symptoms in the scores rated by teachers in 7th and 28th day after menthlphenidate administration compared to baseline score (P<0.05) and 28th day score showed significant improvement compared to 7th day score (P<0.05) and 28th day score showed significant improvement compared to 7th day score (P<0.05). There was significant improvement on symptoms in the scores rated by parents in 28th day after methylphenidate administration improvement compared with 7th day score. In single administration of methylphenidate in Sunday morning score compared to afternoon score (P<0.05). In the administration of significant improvement on symptoms compared with the Sunday morning rating score of parents (P<0.05) and the 28th day comparison was also showed significant improvement on symptoms in the scores rated by teachers compared with the scores rated by parents on symptoms (P<0.05). Among group comparison, all groups showed significant improvements (P<0.05) except conduct disorder & oppositional defiant group.

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Detection of HER2 Status in Breast Cancer: Comparison of Current Methods with MLPA and Real-time RT-PCR

  • Pazhoomand, Reza;Keyhan, Elahe;Banan, Mehdi;Najmabad, Hossein;Karimlou, Masoud;Khodadad, Faranak;Iraniparast, Alireza;Feiz, Farnaz;Majidzadeh, Keivan;Bahman, Ideh;Moghadam, Fatemeh Aghakhani;Sobhani, Atoosa Madadkar;Abedin, Seyedeh Sedigheh;Muhammadnejad, Ahad;Behjat, Farkhondeh
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.12
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    • pp.7621-7628
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    • 2013
  • Human epidermal growth factor receptor (HER) status is an important prognostic factor in breast cancer. There is no globally accepted method for determining its status, and which method is most precise is still a matter of debate. We here analyzed HER2 mRNA expression by quantitative reverse transcription-PCR (qRT-PCR) and HER2 DNA amplification using multiplex ligation-dependent probe amplification (MLPA). In parallel, we performed a routine evaluation of HER2 protein by immunohistochemistry (IHC). To assess the accuracy of the RT-PCR and MLPA techniques, a combination of IHC and fluorescence in situ hybridization (FISH) was used, substituting FISH when the results of IHC were ambiguous (2+) and for those IHC results that disagreed with MLPA and qRT-PCR, this approach being termed IHC-FISH. The IHC results for four samples were not compatible with the MLPA and qRT-PCR results; the MLPA and qRT-PCR results for these samples were confirmed by FISH. The correlations between IHC-FISH and qRT-PCR or MLPA were 0.945 and 0.973, respectively. The ASCO/CAP guideline IHC/FISH correlation with MLPA was (0.827) and with RT-PCR was (0.854). The correlations between the IHC results (0, 1+ as negative, and 3+ as positive) and qRT-PCR and MLPA techniques were 0.743 and 0.831, respectively. Given the shortcomings of IHC analysis and greater correlations between MLPA, qRT-PCR, and FISH methods than IHC analysis alone with each of these three methods, we propose that MLPA and real-time PCR are good alternatives to IHC. However a suitable cut-off point for qRTPCR is a prerequisite for determining the exact status of HER2.

REGULARITY OF TRANSFORMATION SEMIGROUPS DEFINED BY A PARTITION

  • Purisang, Pattama;Rakbud, Jittisak
    • Communications of the Korean Mathematical Society
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    • v.31 no.2
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    • pp.217-227
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    • 2016
  • Let X be a nonempty set, and let $\mathfrak{F}=\{Y_i:i{\in}I\}$ be a family of nonempty subsets of X with the properties that $X={\bigcup}_{i{\in}I}Y_i$, and $Y_i{\cap}Y_j={\emptyset}$ for all $i,j{\in}I$ with $i{\neq}j$. Let ${\emptyset}{\neq}J{\subseteq}I$, and let $T^{(J)}_{\mathfrak{F}}(X)=\{{\alpha}{\in}T(X):{\forall}i{\in}I{\exists}_j{\in}J,Y_i{\alpha}{\subseteq}Y_j\}$. Then $T^{(J)}_{\mathfrak{F}}(X)$ is a subsemigroup of the semigroup $T(X,Y^{(J)})$ of functions on X having ranges contained in $Y^{(J)}$, where $Y^{(J)}:={\bigcup}_{i{\in}J}Y_i$. For each ${\alpha}{\in}T^{(J)}_{\mathfrak{F}}(X)$, let ${\chi}^{({\alpha})}:I{\rightarrow}J$ be defined by $i{\chi}^{({\alpha})}=j{\Leftrightarrow}Y_i{\alpha}{\subseteq}Y_j$. Next, we define two congruence relations ${\chi}$ and $\widetilde{\chi}$ on $T^{(J)}_{\mathfrak{F}}(X)$ as follows: $({\alpha},{\beta}){\in}{\chi}{\Leftrightarrow}{\chi}^{({\alpha})}={\chi}^{({\beta})}$ and $({\alpha},{\beta}){\in}\widetilde{\chi}{\Leftrightarrow}{\chi}^{({\alpha})}{\mid}_J={\chi}^{({\alpha})}{\mid}_J$. We begin this paper by studying the regularity of the quotient semigroups $T^{(J)}_{\mathfrak{F}}(X)/{\chi}$ and $T^{(J)}_{\mathfrak{F}}(X)/{\widetilde{\chi}}$, and the semigroup $T^{(J)}_{\mathfrak{F}}(X)$. For each ${\alpha}{\in}T_{\mathfrak{F}}(X):=T^{(I)}_{\mathfrak{F}}(X)$, we see that the equivalence class [${\alpha}$] of ${\alpha}$ under ${\chi}$ is a subsemigroup of $T_{\mathfrak{F}}(X)$ if and only if ${\chi}^{({\alpha})}$ is an idempotent element in the full transformation semigroup T(I). Let $I_{\mathfrak{F}}(X)$, $S_{\mathfrak{F}}(X)$ and $B_{\mathfrak{F}}(X)$ be the sets of functions in $T_{\mathfrak{F}}(X)$ such that ${\chi}^{({\alpha})}$ is injective, surjective and bijective respectively. We end this paper by investigating the regularity of the subsemigroups [${\alpha}$], $I_{\mathfrak{F}}(X)$, $S_{\mathfrak{F}}(X)$ and $B_{\mathfrak{F}}(X)$ of $T_{\mathfrak{F}}(X)$.