• Korean Journal of Pharmacognosy
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• v.8 no.2
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• pp.49-53
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• 1977

A triterpenoid compound$(C_{30}H_{50}O)$ was isolated from the hydrocarbon and alcohol fraction of the roots of $Codonopsis\;lanceolata\;B_{ENTH}$. et $H_{OOK}$. (Campanulaceae) and it was identified as cycloartenol by physico- chemical data.

• Archives of Pharmacal Research
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• v.13 no.4
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• pp.365-366
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• 1990

A new phenylpropanoid was isolated from the roots of Codonopsis ussuriensis (Rupr. et Maxim) Hemsley. It was coloress crystals, mp. 140-142.deg.C and was elucidated as 4-(3-ethoxy-1-propenyl)-2, 6-dimethoxyphenyl-$\beta$-D-glucopyranoside on basis of spectral data analysis.

• Proceedings of the PSK Conference
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• 2003.04a
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• pp.176.1-176.1
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• 2003

The protective effects on hepatic fibrosis of an aqueous extract from the roots of Platycodon grandiflorum A. DC (Campanulaceae), Changkil (CK), in hepatic stellate cell line, CFSC-2G. The increased deposition of extracellular matrix by hepatic stellate cells following liver injury in a process known as activation is considered a key mechanism for increased collagen content of liver during the development of liver fibrosis. (omitted)

• Proceedings of the PSK Conference
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• 2003.10b
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• pp.159.2-159.2
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• 2003

Codonopside lc is an active natural compound isolated from the roots of Codonopsis lanceolata (Campanulaceae), a Korean medicinal herb. In the present study, we investigated the in vitro effect of Codonopside 1c on the proliferation and induction of apoptosis in HL-60 human promyelocytic cells. When HL-60 cells were treated with Codonopside 1c, evidence of apoptotic features, including DNA fragmentation, formation of DNA ladder in agarose gel elecrophoresis and increse of annexin V binding, were obtained. (omitted)

• Proceedings of the PSK Conference
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• 2002.10a
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• pp.288.2-288.2
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• 2002

Herbal medicines are increasingly being utilized to treat a wide variety of disease processes. We previously reported that aqueous extract from the roots of Platycodon grandiflorum A. DC (Campanulaceae), Changkil (CK). had hepatoprotective effects against acetaminophen induced liver injury. In the present study, we assayed the preventive and therapeutic effects of CK on experimental hepatic fibrosis induced by dimethylnitrosamine (DMN) in rats. (omitted)

• Korean Journal of Pharmacognosy
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• v.42 no.1
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• pp.27-31
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• 2011

The ameliorating effect of the saponin rich fraction (SRF) prepared from the roots extract of Platycodon grandiflorum (Campanulaceae) on the scopolamine-induced cognitive dysfunction in mice were investigated by way of Moris water maze task. The mice with repeated oral administration of the SRF for four weeks showed markedly reduced the swimming time and swimming distance to reach the platform as well as the increase of number of crossing the platform on the Moris water maze task performed after scopolamine intoxication. The results suggest that SRF obtained from the roots extract of P. grandiflorum exert a cognitive enhancing effect on scopolamine-induced memory impairment in mice.

• Korean Journal of Pharmacognosy
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• v.13 no.2
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• pp.55-61
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• 1982

Thirtyfour species of Korean medicinal plants which have been frequently used in oriental herb prescriptions were evaluated on their cytotoxicity and potential antitumor activities against AC glioma(9 ASK) in vitro. Dose of $100{\mu}g/ml$ of plant extracts appeared to exhibit slight cytotoxicity. Seven plant extracts, Aralia continentalis(Araliaceae), Lycium chinensis(Solanaceae), Epimedium koreanum(Berberidaceae), Platyodon grandiflorium(Campanulaceae), Pleuropterus multiflorus(Polygonaceae), Rheum undulatun(Polygonaceae) and Scutellaria baicalensis(Laminaceae), exhibited significant reversal$(51{\sim}90%)$ of astrocyte formation into original neuroglial cells' morphology through the prescreen tests.

• Proceedings of the PSK Conference
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• 2003.04a
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• pp.175.2-176
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• 2003

Herbal medicines are increasingly being utilized to treat a wide variety of disease processes. We previously reported that aqueous extract from the roots of Platycodon grandiflorum A. DC (Campanulaceae), Changkil (CK), had hepatoprotective effects against acetaminophen induced liver injury. In the present study, we assayed the preventive and therapeutic effects of CK on experimental hepatic fibrosis induced by dimethylnitrogamine or carbon tetrachloride in rats. (omitted)

• Korean Journal of Plant Resources
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• v.7 no.2
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• pp.149-150
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• 1994

The plants medicinal resouces of middle area of Korea were investigated 10 times from May 1, 1993 to November 30. 1994. In order to analyze the vegetation of middle wild plants structure and distribu-tion. Medical wiId plants of middle southern area consisted of 100 familis, 380 specis in all. Theresources of important herb drugs were Polypodiaceae, Graminae, Liliaceae, Polygonaceae,Ranunculaceae, Brassicaceae, Rosaceae, Fabaceae, Apiaceae, Labiatae, Solanaceae, Scrophulariaceae,Campanulaceae, Compositae. The herb drugs were comparatively more than in other mountains in ourcountry.

• Korean Journal of Plant Resources
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• v.1 no.1
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• pp.93-116
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• 1988

The plants medicinal resourees of Mt. Joghe were investigeted 10 times from January, 1988 to October, 1988. In order to analyze the vegetation of Joghemountain area, herb plants structure and distribution. Herb plants of Joghe moun-tain consisted of 102 families, 265 species in all. The resources of important herbdrugs were Gramineae, Cyperaceae Oleaceae, Araceae, Polygonaceae, Caryophyllaceae,Ranunculaceae, Theaceae, Cruciferae, Liliaceae, Rosaceae, Geranjaceae, Violaceae,Vitaceae, Umbelliferae, Labiatae, Solanaceae, Campanulaceae, Rutaceae, Compositae,Dioscoreaceae, Fagaeeae, Moraceae, Anacardiaceae, Legum inosae, Cupressaceae, andJuelandaceae. The herb drugs were comparatively more than in other mountains inour country.