• Journal of Korean Neurosurgical Society
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• v.59 no.5
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• pp.466-470
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• 2016

Objective : To determine imaging features that may separate adamantinomatous and papillary variants of craniopharyngiomas given that tumors with adamantinomatous signature features are associated with higher recurrence rates, morbidity, and mortality. We specifically reviewed calcification on CT, T1 bright signal intensity, and cystic change on T2 weighted images for differentiating these two types. Methods : We retrospectively reviewed the MRI and CT studies in 38 consecutive patients with pathologically proven craniopharyngiomas between January 2004 and February 2014 for the presence of calcification on CT scans, bright signal intensity on T1 weighted images, and cystic change on T2 weighted images. Results : Of the 38 craniopharyngiomas, 30 were adamantinomatous type and 8 were papillary type. On CT scans, calcification was present in 25 of 38 tumors. All calcified tumors were adamantinomatous type. Twenty four of 38 tumors had bright signal intensity on T1 weighted images. Of these 24 tumors, 22 (91.7%) were adamantinomatous and 2 were papillary type. Cystic change on T2 weighted images was noted in 37 of 38 tumors; only 1 tumor with papillary type did not show cystic change. Conclusion : T1 bright signal intensity and calcification on CT scans uniformly favor the adamantinomatous type over papillary type of craniopharyngioma in children. However, these findings are more variable in adults where calcification and T1 bright signal intensity occur in 70.6% and 58.8% respectively of adult adamantinomatous types of craniopharyngiomas.

• Archives of Plastic Surgery
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• v.49 no.3
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• pp.360-364
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• 2022

Although capsular contracture represents one of the most important complications after breast augmentation, local inflammation and fibrosis can lead, to capsular calcification, an often-forgotten radiological sign of capsular contracture. In this article, the authors present a clinical case of breast implant calcification in an 81-year-old patient. Although this complication has been rarely described, the literature was reviewed to clarify the role of the local microenvironment in capsular contracture and calcification. At present, capsular contracture patients are classified using the conventional Baker score and the histological Wilflingseder classification. As it was not possible to consider capsular calcification when classifying our patient using the traditional scores, the authors propose an updated version of the current scale.

• Preventive Nutrition and Food Science
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• v.19 no.4
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• pp.363-366
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• 2014

Zinc is considered to be involved in maintaining healthy vascular condition. Atherosclerotic calcification of vascular smooth muscle cells (VSMCs) occurs via the mechanism of cell death; therefore, cell viability is a critical factor for preventing VSMC calcification. In this study, we tested whether zinc affected VSMC viability under both normal physiological non-calcifying (0 mM P) and atherosclerotic calcifying conditions (3 and 5 mM P), since VSMC physiological characters change during the VSMC calcification process. The study results showed that an optimal zinc level ($15{\mu}M$) restored the decreased VSMC viability which was induced under low zinc levels (0 and $1{\mu}M$) and calcifying conditions (3 and 5 mM P) at 9 and 15 days culture. This zinc-protecting effect for VSMC viability is more prominent under atherosclerotic calcifying condition (3 and 5 mM P) than normal condition (0 mM P). Also, the increased VSMC viability was consistent with the decreased Ca and P accumulation in VSMC cell layers. The results suggested that zinc could be an effective biomineral for preventing VSMC calcification under atherosclerotic calcifying conditions.

• Journal of Yeungnam Medical Science
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• v.9 no.2
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• pp.427-435
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• 1992

We have experienced a case of infantile nephrotic syndrome confirmed by renal biopsy in a 13-month-old female patient who showed growth and develop mental retardation and persistent proteinuria. She revealed mild eyelid edema, joint laxity, delayed speech development and adrenal cortical calcification on the radiologic study. Renal biopsy showed microcystic tubular change, micro-glomeruli and marked mesangial proliferation.

• Journal of Physiology & Pathology in Korean Medicine
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• v.22 no.1
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• pp.142-147
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• 2008

This study was purpose to investigate that Gucheokbogol-tang(GBT), mainly used in osteoporosis, has possible regulatory effect on bone regeneration by operating in proliferation and calcification of osteoblast. So that, their cytotoxicity and proliferation was investigated with MTT by ELISA, and morphological change was observed by optical microscope and electron microscope. And activation of alkaline phosphates(ALP) which is secreted in early stage of bone formation was measured, and accumulation of $Ca^{2+}$ in the process of calcification was investigated by alizaline red S assay(ARS). The results were as follows: The MG-63 cell, originated from human cell was activated in $10^{-5}$ treated group, and the level of ALP was also increased in the treated group, highest on the third day. And from the outcome of ARS assay of calcification process in the Gucheokbogol-tang(GBT) treated group for 21days. These results suggested that Gucheokbogol-tang(GBT) is effective in proliferation and calcification of osteoblast.

• Proceedings of the KOSOMBE Conference
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• v.1993 no.05
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• pp.141-145
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• 1993

To Determine the major factor which causes the accelerated calcification of the severe flexing area of the artificial heart sac, comparative study under well defined in vitro situation were carried out. The results show that the effect of static mechanical stress is not so important. According to the data, change of surface area caused by the applied mechanical stress is one of the important factors of the heavy calcification of the severe flexing area of the artificial heart sac.

• Journal of radiological science and technology
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• v.31 no.1
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• pp.61-69
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• 2008

Diagnosis of breast ultrasound is better than mammography in the early detection of breast cancer, but, it is difficult to detect microcalcification. We studied on detection for calcification of breast tissue using acoustic resonance and power doppler with 7.5 MHz linear probe in breast ultrasound. We first constructed breast tissue phantom made of gelatin and saw breast, and then observed calcification by the change of external vibration. Calcification injected breast tissue phantom visualized the difference for brightness and region of color in ROI regions of power doppler. Acoustic resonance almost never visualized in low frequency regions, plateau constituted in about 300-400 Hz and colors vanished according to the increase of frequency.

• Journal of the korean academy of Pediatric Dentistry
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• v.6 no.1
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• pp.53-63
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• 1979

To Study the eruption pattern of the mandibular second permanent molar, the author took 425 cases of Oblique Cephalogram from 6 to 13 years old children and observed the vertical and mesiodistal directional change and tooth axis change. The following results were obtained. : 1. The eruption pattern of the mandibular second permanent molar was changed at about 10.0~10.1 ages or calcification stage IX. 2. At the early stage, the path of eruption of the mandibular second parmanent molar directed upward and forward and after calcification stage IX it changed to the direction of upward. 3. At the early stage, the distance from the distal end of the mandibular first permanent molar to the anterior portion of the ascending ramus was 0.9~1.0 times larger than the mesio-distal diameter of the mandibular second molar, but at the later stage it was increased 1.4 times larger than the mesio-distal diameter of the mandibular second permanent molar.

• Journal of the Korean Society of Radiology
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• v.17 no.5
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• pp.751-759
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• 2023

Breast ultrasonography is difficult to image in fatty breasts and to find micro-calcification, but the discovery of micro-calcification is very important for breast cancer screening. Among the color Doppler artifact of ultrasound, twinkle artifact mainly occur on strong reflectors such as stones or calcification in images, and evaluation methods using them are clinically being used. In this study, we are conducting experiments on the color Doppler settings of ultrasound equipment, such as repetition frequency, ensemble, persist, wall filtering, smoothing, linear density, and dissociation value, by producing a breast simulation phantom using the largest amount of calcium phosphate among breast implants. The purpose of this study was to improve the contrast of twinkle artifact in breast ultrasound examinations and to maximize their use in clinical practice. As a result, the pulse repetition frequency occurred in the range of 3.6 kHz to 7.2 kHz, and did not occur above 10.5 kHz. For ensembles, twinkle artifact occurred in all sizes of calcification under low conditions, and in threshold settings, the twinkle artifact increased slightly only under 80 to 100 conditions, and did not occur in 1 mm size calcification. Persist, wall filter, smoothing, and line density settings did not have much meaning in the setting variable because conditions did not increase by condition, and pulse repetition frequency, ensemble, and thresholds had the greatest impact on the twinkling artifact image. This study is expected to help examiners select optimal conditions to effectively increase twinkle artifact by adjusting color Doppler settings.

• Journal of Korean Neurosurgical Society
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• v.58 no.6
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• pp.566-570
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• 2015

Intramuscular myxoma (IM) is a benign neoplasm of mesenchymal origin. We report a rare case of IM which was located in the lumbosacral paraspinal muscles. A 62-year-old female patient presented with progressive low back pain for 2 months, and the radiologic findings showed a large mass ($4.0{\times}3.5{\times}6.5cm$) in the right lumbosacral paraspinal area. Total resection of the tumor was performed and the symptom was nearly resolved after surgery. Although the immuno-histopathological analysis was consistent with IM, there were some different findings from typical pathological characteristics of IM in this case. Firstly, the symptomatic change of the mass took relatively short time (less than 3 months), and this change was accompanied by partial calcification inside the mass. Moreover, iatrogenic interruption of paravertebral muscle by the other previous operation might be the promoting factor of the fibrous dysplasia, which can explain the pathogenesis of IM. To our knowledge, this is the eighth case of the lumbar paraspinal myxoma reported in the literatures and the first case in Asian population.