• Bulletin of the Korean Chemical Society
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• v.35 no.10
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• pp.3041-3046
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• 2014

Blue emitting materials, 9,10-bis-biphenyl-4-yl-anthracene (AC-P), 9,10-bis-[1,1';4',1"]terphenyl-4-yl-anthracene (AC-DP), and 9,10-bis[3",5"-deiphenyltriphenyl-4'-yl]anthracene (AC-TP) were synthesized through boration and Suzuki aryl-aryl coupling reaction. EL performance of blue light-emitters was optimized and improved by varying the chemical structures of the side groups. In the thin film state, the three materials exhibit $PL_{max}$ values in the range of 442-456 nm. EL device with the synthesized compounds in the following configuration was fabricated: ITO/4,4',4"-tris(N-(2-naphthyl)-N-phenylamino)triphenylamine (2-TNATA) 60nm/N,N'-bis (naphthalene-1-yl)-N,N'-bis(phenyl)benzidine (NPB) 15nm/synthesized blue emitting materials (30nm)/1,3,5-tri(1-phenyl-1H-benzo[d]imidazol-2-yl)phenyl (TPBi) 20nm/LiF 1nm/Al 200nm. The current efficiency and C.I.E. value of AC-TP were 3.87 cd/A and (0.15, 0.12). A bulky and non-planar side group helps to prevent ${\pi}-{\pi}^*$ stacking interaction, which should lead to the formation of more reliable amorphous film. This is expected to have a positive effect on the high efficiency of the operating OLED device.

• Journal of Korean Society of Water and Wastewater
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• v.21 no.1
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• pp.113-122
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• 2007

Experimental studies were performed to investigate speciation and leaching potential of heavy metals(Cu, Cd, Pb Zn, Ni) in ten sediment samples collected from Nakdong River. Acid Volatile Sulfide (AVS) and Simultaneously Extractable Metals (SEM) measurements were used to estimate heavy metals that can be leached under anaerobic conditions. Sequential Extraction Procedure (SEP) and Toxicity Characteristic Leaching Procedure (TCLP) were used to characterize speciation and leaching potential of heavy metals under aerobic conditions. The results show that total concentrations of Cu, Zn and Ni were relatively high in the sediments from points Seongseo industrial complex stream (upper stream) (D), Seongseo industrial complex stream (midstream) (E), Dalseo stream (F), and Nakdong river estuary (J), and that Cd concentrations were higher in all sampling points except for Goriung Bridge (G) and Soosan Bridge (H). SEM and AVS analyses reveal that samples from points Ilsun Bridge (A), Namgumi Bridge (C), and Soosan Bridge (H) have potential of heavy metals leaching, although leachable concentrations are relatively low. The leaching potential of heavy metals in other points was low because of higher concentrations of AVS than SEM. SEP results show that more than 50% of Cu, Zn and Ni were present in residual fraction, which means these metals are less amenable to leaching in anaerobic conditions. On the other hand, more than 50% of Pb and Cd were extracted during the first through third step of the SEP, which means substantial fraction of these metals can be leached upon changing of redox conditions. TCLP tests predict that leaching potential of heavy metals was generally low, which is consistent with the results obtained by AVS and SEM measurements.

• Journal of Microbiology and Biotechnology
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• v.23 no.4
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• pp.451-458
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• 2013

The human gastric pathogen Helicobacter pylori (Hp) has been considered a microaerophile. However, we recently reported that, when supplied with 10% $CO_2$, Hp growth is stimulated by an atmospheric level of $O_2$, suggesting that Hp is a capnophilic aerobe. In this study, we investigated the effects of aerobic $O_2$ tension on Hp cells by comparing gene expression profiles of cultures grown under microaerobic and aerobic conditions in the presence of 10% $CO_2$. The results showed that overall differences in gene expression in Hp cells grown under the two $O_2$ conditions were predominantly growth-phase-dependent. At 6 h, numerous genes were down-regulated under the aerobic condition, accounting for our previous observation that Hp growth was retarded under this condition. At 36 h, however, diverse groups of genes involved in energy metabolism, cellular processes, transport, and cell envelope synthesis were highly up- or down-regulated under the aerobic condition, indicating a progression of the cultures from the log phase to the stationary phase. The expression of several oxidative stress-associated genes including tagD, katA, and rocF was induced in response to aerobic $O_2$ level, whereas trxA, trxB, and ahpC remained unchanged. Altogether, these data demonstrate that aerobic $O_2$ tension is not detrimental to Hp cells but stimulates Hp growth, supporting our previous finding that Hp may be an aerobic bacterium that requires a high $CO_2$ level for its growth.

• Journal of the Korean Society of Food Science and Nutrition
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• v.32 no.2
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• pp.207-210
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• 2003

This study was designed to investigate the antioxidative effect of glasswort (Salicornia herbacea L.) grown in closed sea beach. To compare antioxidant effects of glasswort plant parts, dried ground leaves, stems, and roots of glasswort were exploited for investigation of antioxidant activity Antioxidant activity for the samples was investigated by Rancimat and TBA method. The oxidative stability determined by the Rancimat technique showed a variation in antioxidative index (AL) between the different plant parts, ranging from 1.0 to 3.6. Oxidative stability from ground stem sample of glasswort harvested in the closed sea beach was the highest, and followed by leaf and root. Stem had higher oxidative stability than ascorbic acid. Antioxidatiue effects of glasswort were increased in dose-dependent manners, and antioxidant activity by addition of glasswort with same amount to 4% oil was similar to the activity of ascorbic acid. Specially, 8~10% glasswort addition to oil showed similar antioxidative effect to 1% $\alpha$-tocopherol.

• Korean Journal of Clinical Pharmacy
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• v.21 no.4
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• pp.353-363
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• 2011

The World Health Organization (WHO) declared the outbreak of H1N1 pandemic in 2009. South Korea also had outbreaks of H1N1 virus and used oseltamivir in large volume with increased reports of adverse drug reaction(ADR). The present study was aimed to investigate the ADR frequency, the factors related to ADR, and characteristics of oseltamivir's ADR. Participants for the study were patients randomly drawn from those who were prescribed oseltamivir for treatment from CHA Bundang Medical Center during October 1 and October 30. The information examined as factors related to ADR were collected by a subsequent cross-sectional telephone survey. The factors are the following; a) age; b) gender; c) patient medical history; d) diagnosis of H1N1 virus; e) adherence; f) whether taking other medication with oseltamivir or not; and g) the number of combined medications. We also asked ADR after taking oseltamivir. Total subjects were 86 patients. The average age is $22.6{\pm}18.48$ years old. The gender was 45.3% women and 54.7% men. Half (50%) of all respondents showed one or more ADR, 67.4% were positively diagnosed for H1N1 virus, and 54.7% were completed the full course of oseltamivir (i.e. twice daily x 5days). The most frequently reported ADR symptoms were: dizziness (15.1%), nausea (11.6%), lethargy (10.4%), diarrhea (10.4%), abdominal pain (8.1%), headache and vomiting (6.9%). ADR classifications by categories are gastro intestinal (44.2%), neuropsychiatric events (22.1%), systemic symptom (20.9%), skin events (5.8%), eye events (4.7%), and other cases (2.3%). The onset of ADR 'after taking 1~3 doses' was 69.7%. No increase in neuropsychiatric events was detected in children and adolescents. No factors examined for the study do have significant influence on the presence of ADR. This study showed that ADR of oseltamivir have occurred in half of the patients. The use of oseltamivir is essential for treatment and prophylaxis of influenza A(H1N1). But mass treatment should be properly monitored for ADR.

• Journal of Ginseng Research
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• v.19 no.3
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• pp.225-230
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• 1995

The effect of long-term ginseng (Panax ginseng C.A. Meyer) administration on the clearance of carboxyhemoglobin (CO-Hb) and the property of blood gases was investigated in rats. Rats were received ginseng water extract (0.025% in drinking water) for 42 weeks starting at the age of 6 weeks. They were exposed to the diluted mainstream smoke generated from 15 filter cigarettes for 20 min in a round polycarbonate chamber (D37 cmXH13 cm). Under this condition, the mean CO-Hb content of control and the ginseng-treated rats immediately after the exposure was nearly the same as 13.8$\pm$2.9 f) and 13.9$\pm$1.6%, respectively. However, CO-Hb was more rapidly removed from blood in the ginseng treated rats than in untreatEd control with the laps of time, namely, its biological half life In the former was 36.9$\pm$1.5 min and in the latter was 56.9$\pm$13.2 min. Although long-term ginseng treatment did not affect the content of hemoglobin and blood pH of rats, it slightly increased blood oxygen content and its partial pressure value, and decreased levels of carbon dioxide and bicarbonate. These results suggest that long-term administration of rats with ginseng extract accelerate the elimination of CO from the blood. This effect seems to be related to the enhancement of oxygen consumption of the rat by a certain action of ginseng components as previously reported.

• Journal of the Korea Safety Management & Science
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• v.17 no.2
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• pp.117-127
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• 2015

This study investigated the smoke blocking and control systems for the safety of residents evacuation and for the prevention of smoke spread through the central corridor in the event of central corridor type of intelligent building fire. We offered additional ways of utilizing smoke ventilators and intake ventilation equipment and utilized CFD-based fire simulation program(FDS Ver.5.5.3) in order to analyze the effect. As a result, many differences in the smoke block effect, depending on the application of smoke ventilator and location of installation, was found. In addition, the result was found that larger effect was showed not in the case of application of smoke ventilator in central corridor only but application in fire room. The reason is that the smoke leakage is blocked primarily as air is flowed in the fire room through open door by operation of intake smoke ventilator in the public corridor and secondarily, the smoke leakage to the public corridor could be blocked as fire and smoke were released to the opened smoke ventilator continuously. Especially, the effect was maximized through complex interactions by applying smoke ventilator and intake ventilation equipment in corridor together rather than applying smoke ventilator and intake ventilation equipment independently. The proposed measure through this study shall be considered from architectural plan as one of ways for blocking from smoke spread to the central corridor in the central corridor type of intelligent building. In addition, flaws on regulation shall be established and supplemented.

• Korean Journal of Plant Resources
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• v.20 no.3
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• pp.234-241
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• 2007

The present study was undertaken to classify and describe the riparian vegetation of the 6 river${\cdot}$stream of Korea Peninsula. As a result the vegetation was divided into nineteen communities. The vegetation units obtained in the present study were as follow: A: Salix koreensis community, B: Salix gracilistyla community, C: Robinia pseudo-acacia community, D: Amorpha fluticosa community, E: Brousonnetia papyrifera community, F: Phyllostachys bambusoides community, G: Rubus corchorifolius community, H: Phramities japonica community, I: Phramites communis community, J: Miscanthus sacchariflorus community, K: Miscanthus sinesis var. purpurascens community, L: Artemisia princeps var. orientalis community, M: Humulus japonicus community, N: Zoysia japonica community, O: Inperata cylindrica var. koenigii community, P: Agropyron tsukushiense var. transiens community, Q: Juncos effusus var. decipiens community, R: Rumex crispus community, S: Persicaria hydropiper community. The vegetation characteristics of riversides was recovered in the surveyed results according to river${\cdot}$stream basin, in other words, 10 communities in the upper river${\cdot}$stream riparian, 15 communities in the middle river${\cdot}$stream riparian, 10 communities in the down river${\cdot}$stream riparian. The Phragmites japonica community in the upper and Phragmites communis community in the down was analyzed by common community of the 6 river${\cdot}$stream riparian, respectively, but none in the middle. The standing profile of vegetation across 6 river${\cdot}$stream was seen stepwise Phragmites japonica community, Salix gracilistyla community, Miscanthus sinensis var. purpurascens community, shrub community by natural waterway in the upper, Salix gracilistyla community, Phragmites communis community, Rumex crispus community, Miscanthus sacchariflorus community, Humulus japonicus community in the middle, Phragmites communis community in the down. The differences of distributional featurs of vegetation emerged from the riparian of the 6 river${\cdot}$stream, but don't from the 6 river${\cdot}$stream.

• Korean journal of applied entomology
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• v.8
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• pp.11-18
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• 1969

식물 생장 조절제로서 phthalamic acid와 그 유도체를 사용하여 추락답을 개량하기 위한 예비 시험을 실시하여 다음과 같을 결과를 얻었다. 1) 아래 7종의 phthalamic acid 및 그 유도체를 합성 또는 정제하여 공시약제로 하였으며 합성품의 수율은 $87-92\%$였다. (표 1) A. Phthalamic acid B. Phthalanilic acid C. N- (o-Chlorophenly)-phthalamic acid D. N-(p-Chlorophenyl)-phthalamic acid E. N- (3,4-Dichlorophenyl)-phthalamic acid F. Sodium-N- (m-tolyl)-phthalamate (Duraset) G. Sodium-N-(1-naphthyl)-phthalamate (Alanap) 2) Wheat straight growth test에서 공시약제는 10ppm 및 20ppm의 농도에서 Control보다 월등한 생장 촉진효과를 보였으며 특히 흥미있는 것은 phthalamic acid 유도체가 phthalamic acid 자체보다 더 좋은 효과를 보였다. (표4, 그림 1) 3) 수도 종자의 발아 시험 결과 초장은 phthalamic acid 유도체가 적시 phthalamic acid 자체보다 좋았으며 기중 Alanap. 3,4-dichlorophenyl phthalamic acid 및 Duraset가 가장 좋았으나 10-100ppm 범위내의 농도에 거의 영향없었다. (표 5) 근의 생육은 일반적으로 약제의 종류에 따라 상이할 뿐 아니라 초장의 생육보다 더욱 약제에 민감하였다. 근장은 phthalamic acid, phthalanilic acid, (p-chlorophenyl)phthalamic acid, 3,4-dichlorophenyl phthalamic acid가 Control 보다 약간 좋은 효과를 보였고, Alanap은 매우 불량하였다. (표 6) 근수는 (p-chlorohhenyl) phthalamic acid만 Control에 비해 우수하였고 나머지 약제는 대체로 근수를 감소시키거나 Control과 비슷한 효과를 보였다. (표 7) 또한 농도가 증가함에 따라 근수는 감소하였으며, Alanap, (o-chlorophenyl) phthalamic acid는 근단에 심한 약해가 일어났다. 4) 전근시험에서 근수는 공시약제에 의하여 증가되었으나 50-200ppm의 농도에서 별 영향이 없었다.(표 8, 그림 2) 근장은 농도가 증가함에 따라 감소되는 영향이었으나 공시약제에는 상이한 효과를 보였다. 5) 이상 결과에서 p-chlorophenyl phthalamic acid 및 3,4-dichlorophenyl phthalamic acid가 수도용 식물생장조절제로서 실용적 개발의 가능성을 보였다.

• The Korean Journal of Rehabilitation Nursing
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• v.5 no.2
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• pp.193-204
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• 2002

This study was a quasi-experimental study of nonequivalent control group pretest- posttest design to investigate the effect of aerobic walking exercise program on the physical & psychological functions of home stayed stroke patients. The data were collected during the period of May 20th to August 15th, 2001. The subjects for this study were 40 hemiplegic stroke patients with the experimental group consisting of 19 patients and the control group being composed of 21 patients. The patients selected for this study were: (a)living in J city who had been diagnosed with stroke and at home after being discharged from the hospital, (b)suffering from stroke for 6 months to 5 years, (c)without recognition disorder with the MMSE-K score above 25, (d)below 2 on the modified Ashworth scale, (e)free from heart and pulmonary disease (f)able to walk beyond 15 minutes for themselves. The aerobic walking exercise program for the experimental group was aerobic exercise and education and supportive care. The aerobic exercise was 8 weeks' period, three times a week, 35 to 50 minutes a day. And the education and supportive care was consisted of one home visiting and 2 times telephoning a week. The data were analysed by $X^2$-test, paired t-test and unpaired t-test and ANCOVA through SAS/PC program. The results of the study were as follows: 1. There was insignificant difference in the gait length experimental and control group. There was significant difference in the gait speed between the two groups. 2. There was significant difference in the dynamic valance between the two groups. 3. There was significant difference in ADL score between the two groups. 4. There was no significant difference in the depression between the two groups. As shown above, the results of 8 weeks' the aerobic walking exercise program for home stayed stroke patients produced positive effects on gait speed, dynamic valance, ADL score. And this program was expected that it was more effective in different intervention period, verified program. Also it was needed follow study.