• Journal of Chest Surgery
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• 제40권4호
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• pp.273-279
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• 2007

배경: 체외순환으로 발생하는 전신성 염증반응을 줄이기 위해 체외순환 회로의 표면에 초친수성 표면개질을 시행한 후 혈장 단백의 흡착 및 혈소판의 변화를 관찰하였다 대상 및 방법: 60kg 내외의 돼지 10마리를 대상으로 하였다. 체외순환은 좌심방과 상행대동맥에 캐눌라를 거치하여 원심성 바이오펌프를 이용해 2시간 동안 정상체온 하에서 시행하였다. 이때 실험군(n=5)에서는 체외순환회로에 초친수성 표면처리를 하였으며 대조군(n=5)에서는 상용화된 일반적인 튜빙을 사용하였다. 체외순환에 따른 염증반응의 정도를 비교하기 위하여 혈소판 수 및 응집능 검사, 트롬빈-안티트롬빈 복합체 검사, 그리고 혈액 내 총 단백량을 측정하였다. 결과: 양 군에서 모두 혈소판의 수 및 응집능 기능검사에서 유의한 차이를 보이지 않았으며 또한 트롬빈-안티트롬빈 복합체의 농도에서도 두 군 간에 유의한 차이를 보이지 않았다. 그러나 총 단백량의 측정에서는 체외순환 후 대조군에서 실험군에 비해 유의하게 감소되었다. 결론: 초친수성 표면처리는 체외순환 시 혈장 단백의 표면흡착에 따른 혈장 단백의 감소를 줄일 수 있었으나 이로 인한 염증반응의 감소효과는 관찰할 수 없었다.

• 한국연소학회:학술대회논문집
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• 한국연소학회 제26회 KOSCO SYMPOSIUM 논문집
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• pp.111-117
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• 2003

The present study discusses about the combustion and thermal flow characteristics of a G+R type incinerator, which is under construction for MAPO Incineration system, to evaluate the effects of various operating and design parameters. A bed combustion model is developed to simulate the waste bed combustion on the stoker. The effects of waste composition and primary air distribution are estimated. The results of the waste bed combustion model is applied to CFD(computational fluid dynamics) simulation, which simulates the detail of the thermal flow in the combustion chamber. The effects of bypass damper opening ratio, primary air distribution, and secondary air jet configuration are discussed.

• 한국자동차공학회논문집
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• 제21권4호
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• pp.181-187
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• 2013

Performance of DI diesel engine with high fuel injection method is directly related to its emission characteristics and fuel consumption. In this study, numerical model of 3rd generation piezo-driven injector was designed to analyze the hydraulic performance. Also the injection response characteristics was investigated by using the AMESim simulation code. From this study, it was shown that 3rd generation piezo-driven injector had a faster response and had better control capability due to its hydraulic bypass-circuit that has potential to higher hydraulic characteristics and improved accuracy of injected fuel quantity.

• 한국원자력학회:학술대회논문집
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• 한국원자력학회 2003년도 추계학술발표대회 요약집
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• pp.83.2-83.2
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• 2003

• Journal of Mechanical Science and Technology
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• 제19권5호
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• pp.1158-1168
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• 2005

A shunt from the left ventricle to the left anterior descending artery is being developed for coronary artery occlusive disease, in which the shunt or conduit connects the the left ventricle (LV) with the diseased artery directly at a point distal to the obstruction. To aid in assessing and optimizing its benefit, a computational model of the cardiovascular system was developed and used to explore various design conditions. Computational fluid dynamic analysis for the shunt hemodynamics was also done using a commercial finite element package. Simulation results indicate that in complete left anterior descending artery (LAD) occlusion, flow can be returned to approximately 65% of normal, if the conduit resistance is equal for forward and reverse flow. The net coronary flow can increase to 80% when the backflow resistance is infinite. The increases in flow rate produced by asymmetric flow resistance are enhanced considerably for a partial LAD obstruction, since the primary effect of resistance asymmetry is to prevent leakage back into the ventricle during diastole. Increased arterial compliance has little effect on net flow with a symmetric shunt, but considerably augments it when the resistance is asymmetric. The computational results suggest that an LV-LAD conduit will be beneficial when the resistance due to artery stenosis exceeds 27 PRU, if the resistance is symmetric. Fluid dynamic simulations for the shunt flow show that a recirculating region generated near the junction of the coronary artery with the bypass shunt. The secondary flow is induced at the cutting plane perpendicular to the axis direction and it is in the attenuated of coronary artery.

• Journal of Chest Surgery
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• 제39권7호
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• pp.505-510
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• 2006

배경: 쥐를 이용한 심폐바이패스 모델은 시간 및 비용의 절감, 관리의 용이, 큰 실험실의 불필요, 그리고 반복실험의 용이 등 많은 장점이 있으나 기술적인 어려움 또한 크다. 열교환기를 이용한 효율적인 중심체온 유지 및 조절 역시 이러한 문제점 중의 하나이다. 이에 본 연구에서는 쥐 심폐바이패스 모델을 위해 기존의 상용화된 산화기를 소동물용으로 개조한 뒤 심정지액 주입용 소형 열교환기를 이용하여 충전액을 최소화한 상태에서 인공심폐기에 의한 효율적인 체온 유지가 가능한지를 보고자 하였다. 대상 및 방법: 수컷 쥐(Sprague-Dawley,평균 530 g) 10마리를 각 5예씩 나누어 열교환기를 사용한 군과 사용하지 않은 군으로 구분하였다. 열교환기는 심정지액 주입용 열교환기를 개조하여 사용하였으며 산화기를 포함한 전체 정지 충전용량은 40 cc였다. 열교환기를 사용하지 않은 군에서는 저혈조 주위에 온수를 순환시켰다. 실험동물 마취 후 동맥 삽관은 대퇴동맥 및 내경동맥에 정맥 삽관은 외경정맥에 시행하고 부분 심폐바이패스(40 ml/kg/min)를 20분간 유지하였다. 두 군간의 비교 분석을 위해 직장 체온을 각각 마취 직후, 동정맥 삽관 후, 심폐바이패스 후 5, 10, 15, 20분에 측정하였다. 심폐바이패스 후 5, 15분에는 헤모글로빈 및 동맥혈 가스분석을 동시에 측정하였다. 결과: 쥐에서의 심폐바이패스 운용은 안정적으로 유지되었으며, 심폐바이패스 후 5분부터 두 군간의 체온 차이는 유의하였다(p<0.01). 20분 후 체온은 각각 $36.16{\pm}0.32^{\circ}C$ 및 $34.22{\pm}0.36^{\circ}C$였다. 결론: 본 연구는 소동물 심폐바이패스 모델에서 심정지액 주입용 열교환기를 이용하여 충전액에 대한 영향을 최소화하면서 효율적인 체온유지가 가능함을 증명하였다. 이러한 실험 결과는 향후 저체온 심폐바이패스 운용에 관한 실험 모델로 쥐를 폭넓게 이용할 수 있다는 가능성을 제시한다는 점에서 그 의의가 크다.

• 한국추진공학회:학술대회논문집
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• 한국추진공학회 2011년도 제37회 추계학술대회논문집
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• pp.842-849
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• 2011

Open Rotor 엔진은 차세대 항공기를 위한 잠재적 기술향상을 제공할 수 있는 여러 신기술중의 하나이다. Open Rotor 엔진은 일반적 고바이패스 터보팬 엔진보다 향상된 추진 저하율을 가지며 고바이패스비와 공기역학적 진보한 형상의 팬 블레이드 설계의 결합으로 우수한 연료소모율을 구현한다. Open Rotor 엔진 성능 모델은 F404 터보제트 엔진를 코어로 사용한 GE36 엔진의 설계 및 시험데이터를 기반으로 해석하였다. 시험데이터를 이용하여 Open Rotor 엔진 성능 모델을 검증하였으며 최신 차세대 터보프롭 엔진 성능과의 비교를 통하여 적절하게 구성되었음을 확인하였다.

• Journal of Preventive Medicine and Public Health
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• 제34권3호
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• pp.244-252
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• 2001

Objective : Health insurers and policy makers are increasingly examining the hospital mortality rate as an indicator of hospital quality and performance. To be meaningful, a risk-adjustment of the death rates must be implemented. This study reviewed 5 severity measurement methods and applied them to the same data set to determine whether judgments regarding the severity-adjusted hospital mortality rates were sensitive to the specific severity measure. Methods : The medical records of 584 patients who underwent coronary artery bypass graft surgery in 6 general hospitals during 1996 and 1997 were reviewed by trained nurses. The MedisGroups, Disease Staging, Computerized Severity Index, APACHE III and KDRG were used to quantify severity of the patients. The predictive probability of death was calculated for each patient in the sample from a multivariate logistic regression model including the severity score, age and sex to evaluate the hospitals' performance, the ratio of the observed number of deaths to the expected number for each hospital was calculated. Results : The overall in-hospital mortality rate was 7.0%, ranging from 2.7% to 15.7% depending on the particular hospital. After the severity adjustment, the mortality rates for each hospital showed little difference according to the severity measure. The 5 severity measurement methods varied in their statistical performance. All had a higher c statistic and $R^2$ than the model containing only age and sex. There was a little difference in the relative hospital performance evaluation by the severity measure. Conclusion : These results suggest that judgments regarding a hospital's performance based on severity adjusted mortality can be sensitive to the severity measurement method. Although the 5 severity measures regarding hospital performance concurred, more often than would be expected by chance, the assessment of an individual hospital mortality rates varied by the different severity measurement method used.

• 대한기계학회논문집B
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• 제25권3호
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• pp.305-314
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• 2001

A modified model is proposed for calculation of transitional boundary layer flows. In order to develop the eddy viscosity model for the problem, the flow is divided into three regions; namely, pre-transition region, transition region and fully turbulent region. The pre-transition eddy-viscosity is formulated by extending the mixing length concept. In the transition region, the eddy-viscosity model employs two length scales, i.e., pre-transition length scale and turbulent length scale pertaining to the regions upstream and the downstream, respectively, and a universal model of stream-wise intermittency variation is used as a function bridging the pre-transition region and the fully turbulent region. The proposed model is applied to calculate three benchmark cases of the transitional boundary layer flows with different free-stream turbulent intensity (1%∼6%) under zero-pressure gradient. It was found that the profiles of mean velocity and turbulent intensity, local maximum of velocity fluctuations, their locations as well as the stream-wise variation of integral properties such as skin friction, shape factor and maximum velocity fluctuations are very satisfactorily predicted throughout the flow regions.

• 반도체디스플레이기술학회지
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• 제21권1호
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• pp.114-118
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• 2022

The photovoltaic system is affected by various conditions such as temperature and irradiance. Because non-uniform irradiation and partial shading conditions affect the entire string of cells connected in series, a bypass diode is used to bypass the current flow normally. In order to find the maximum power point in partial shade conditions, it is necessary to estimate various methods of maximum power point tracking. In this paper, the hybrid method of MPPT using Lambert W function and perturbation & observation algorithm is proposed under partial shading conditions. The simulation results are obtained using MATLAB/Simulink and shows the improvement of the accuracy of MPPT.