• Journal of Chest Surgery
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• v.35 no.1
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• pp.1-10
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• 2002

Background: Despite the relatively high mortality rates in the chronic heart failure model induced by coronary artery ligation are relatively high, this model has been a subject of continuos research because of its clinical correlation. Chronic heart failure model of large-sized animals is very useful to analyse mechanical or biological effects on circulatory system which is difficult in small-sized animals. The purpose of this study is to establish the heart failure model by coronary artery ligation in sheep. Material and Method: Among 9 Corridale sheep, the homonymous artery and the diagonal branch were ligated simultaneously in 2 sheep and remaining 7 sheep were assigned to successive ligation of both arteries at an interval of 1 hour. Both coronary arteries were ligated from the point 40% proximal to the apex of the heart. Hemodynamic and echocardiographic parameters were analyzed before the ligation of the coronary artery, after the ligation of the homonymous artery, and after additional ligation of the diagonal branch. The experimental animals were sacrificed after 2 or 3 months of growth and histopathologic studies were performed Result: Immediate postoperative death occurred in the 2 sheep that had received simultaneous ligation of the homonymous artery and diagonal branch. On the other hand, all the 7 sheep that were lifated in succession were survived up to 3 months. Arterial pressure was sifnificantly decreased immediately after ligation of the homonymous artery(p<0.05), and the cardiac output was decreased and pulmonary capillary wedge pressure was increased after further ligation of the diagonal branch(p<0.05). Central venous pressure, pulmonary artery pressure, pulmonary capillary wedge pressure, left ventricular end-diastolic dimension and end-systolic dimension were markedly increased 3 months after ligation of coronary arteries. Anteroseptal akinesia or dyskinesia was developed after the ligation of coronary arteries. Histopathologic study revealed we]1-demarcated ischemic area of fibrosis. Conclusion: Using methods of successive ligation of the homonymous artery and diagonal branch, chronic heart failure model could be reliably established in sheep.

• Journal of Computational Design and Engineering
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• v.1 no.2
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• pp.116-127
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• 2014

This paper aims to review methods for computing orthogonal projection of points onto curves and surfaces, which are given in implicit or parametric form or as point clouds. Special emphasis is place on orthogonal projection onto conics along with reviews on orthogonal projection of points onto curves and surfaces in implicit and parametric form. Except for conics, computation methods are classified into two groups based on the core approaches: iterative and subdivision based. An extension of orthogonal projection of points to orthogonal projection of curves onto surfaces is briefly explored. Next, the discussion continues toward orthogonal projection of points onto point clouds, which spawns a different branch of algorithms in the context of orthogonal projection. The paper concludes with comments on guidance for an appropriate choice of methods for various applications.

• Journal of the Korean Operations Research and Management Science Society
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• v.25 no.4
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• pp.15-25
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• 2000

In this paper, we introduce a point-to-multipoint minimum cost flow problem with convex and demand splitting. A source node transmits the traffic along the tree that includes members of the point-to-multipoint connection. The traffic is replicated by the nodes only at branch points of the tree. In order to minimize the sum of arc costs, we assume that the traffic demand can be splitted and transmitted to destination nodes along different trees. If arc cost is linear, the problem would be a Steiner tree problem in networks eve though demand splitting is permitted. The problem would be applied in transmitting large volume of traffic from a serve to clients in Internet environments. Optimality conditions of the problem are presented in terms of fair tree routing. The proposed algorithm is a finite terminating algorithm for $\varepsilon$-optimal solution. convergence of the algorithm is obtained under monotonic condition and strict convexity of the cost function. Computational experiences are included.

• Journal of applied mathematics & informatics
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• v.26 no.5_6
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• pp.1169-1183
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• 2008

In this paper, a method to find the weighted possibilistic variance and moments about the mean value of fuzzy numbers via applying a difuzzification using minimizer of the weighted distance between two fuzzy numbers is introduced. In this way, we obtain the nearest weighted point with respect to a fuzzy number, this main result is a new and interesting alternative justification to define of weighted mean of a fuzzy number. Considering this point and the weighted distance quantity, we introduce the weighted possibilistic mean (WPM) value and the weighted possibilistic variance(WPV) of fuzzy numbers. This paper shows that WPM is the nearest weighted point to fuzzy number and the WPV of fuzzy number is preserved more properties of variance in probability theory so that it can simply introduce the possibilistic moments about the mean of fuzzy numbers without problem. The moments of fuzzy numbers play an important role to estimate of parameters, skewness, kurtosis in many of fuzzy times series models.

• The Korean Journal of Pain
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• v.9 no.1
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• pp.105-108
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• 1996

Localized or radiating pain in the arm and shoulder joint may result after faulty alignment causing compression or tension on nerves, blood vessels, or supporting soft tissues. The critical site of faulty alignment is the quadrangular space in the axilla bounded by the teres major, teres minor, long head of triceps, and humerus. The axillary nerve emerges through this space to supply the deltoid and teres minor. The activity of the trigger point on teres minor compressing the axillary nerve causes pain to develop through the area of sensory distribution of cutaneous branch of the axillary nerve. Relieving compression on the axillary nerve and suprascapular nerve is the key point to relieving the pain. Spasm of the supraspinatus and infraspinatus compressing the suprascapular nerve caused pain to develop in the shoulder joint and scapular area. We treated those patients experiencing such pain with local anesthetic infiltration or I-R laser stimulation on the identified trigger points.

• The Transactions of the Korean Institute of Electrical Engineers
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• v.31 no.7
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• pp.11-17
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• 1982

In this paper, a reliable and convenient evaluation method for the adequacy of any radial distribution line's voltage drop is proposed for improvement of the voltage regulation of the distribution line under operation. Using the voltage measurement of the first load branch point and the last point on the given distribution line its average line voltage drop and the line voltage drop variance by pure load variation are computed. And by these values and allowable or required line drop from proper voltage regulation view point, present adequency index and operation improvement index of the line drop are newly introduced for the evaluation of the given distribution line's voltage regulation. As a result of application to the 4 cases of study, the proposed method is proved to be reliable and convenient.

• Structural Engineering and Mechanics
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• v.18 no.2
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• pp.195-209
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• 2004

By means of the two-dimensional basic equations of transversely isotropic magneto-electro-elastic media and the strict differential operator theorem, the general solution in the case of distinct eigenvalues is derived, in which all mechanical, electric and magnetic quantities are expressed in four harmonic displacement functions. Based on this general solution in the case of distinct eigenvalues, a series of problems is solved by the trial-and-error method, including magneto-electro-elastic rectangular beam under uniform tension, electric displacement and magnetic induction, pure shearing and pure bending, cantilever beam with point force, point charge or point current at free end, and cantilever beam subjected to uniformly distributed loads. Analytical solutions to various problems are obtained.

• Horticultural Science & Technology
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• v.18 no.1
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• pp.22-27
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• 2000

National plant quarantine inspector of exporting country should inspect agricultural products according to the quarantine requisites of counterpart country when the commodities are shipped. Export of pear fruits was held because quarantine pests including Conogethes punctiferalis were found at the point of entry in Canada. In order to examine the problems in detail, the inspected pear fruits were stored at a low temperature for 43 days, almost the same period necessary for fruit sorting, quarantine procedures, and transportation by ship. Dead larvae of fruit moths, C. punctiferalis and Grapholita molesta were found during cold storage. Quarantine pathogens were not found, but non-quarantine ones such as Penicillium sp. was infected through wounds by bruises and stabs resulted from sorting procedures. Because of the wounding problem during export procedures, pear fruits with thin exocarp, such as fruits of P. pyrifolia Nakai cv. Whangkeumbae, are required more careful handling during fruit sorting and conveyance.

• Asian Pacific Journal of Cancer Prevention
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• v.17 no.sup3
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• pp.257-261
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• 2016

Cancer causes cells to avoid death while being the second cause of death in the world itself. Damaged cells in the absence of apoptosis will increasingly amplify their inefficient genome. Of the two main apoptosis inducing pathways in cells, the first has p53 protein as the main initiating factor in the cascade. According to research results this protein s mutated in 50% of cancers and sointerest has cooncentrated on the second pathway that features death receptors. Among these receptors TRAIL1/DR5 is especially expressed in cancer cells. So targeting such receptors can initiate the apoptotic cascade in cells. Interestingly by substitution of activating ligands with antibodies as agonists, we could efficiently turn on the apoptosis pathway. First of all, three small peptides from the DR5 protein extracellular domain were synthesized and injected with two different kind of adjuvants (Fround and liposomal encapsulation) separately into mice at 15 day intervals. As a result, liposomal peptides induced the immune system more efficient than Frounds adjuvant and at the end point the antibodies which were obtained from liposomal peptide injection induced much more effective death. Liposomal formol could be used as an adjuvant in immunization utilizing small peptides. They carry, protect and deliver peptides very efficiently. In addition, small peptides of a certain size from the extracellular domain of DR5 proteins not only can induce immune system but also produce antibodies playing a remarkable anti-cancer roles against breast cancer cells (MCF-7).

• Korean Journal of Materials Research
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• v.24 no.2
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• pp.73-80
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• 2014

Ink-jet printing technology has been widely attractive due to its facility for direct and fine printing on various substrates. Recent studies have focused on expanding the application of ink-jet printing technology from general consumer use and design companies to the prototype production of precision parts and parts manufacturing. The use of ink-jet printing technology in decorated tableware, tiles, and other ceramic products also has many advantages. The printing process is fast and can be adaptable to various kinds of objects because there is no direct contact point between the printer and the substrates to be printed. For application to ceramic product decoration, inks containing highly dispersed inorganic nano-pigments are required. Here we report the synthesis and characterization of blue $CoAl_2O_4$ nanopigment for ink-jet printing. Blue ceramic ink based on the obtained $CoAl_2O_4$ pigment was prepared by dissolving $CoAl_2O_4$ pigment in a mixed solution of ethylene glycol and ethanol with volume ratios of 7:3 and 8:2, respectively, to obtain the appropriate viscosity for ink-jet printing. The ink solution contained 15 wt% of $CoAl_2O_4$ pigment and Cetyltrimethyl ammonium bromide(CTAB) and Sodium dodecyl sulfate(SDS) as dispersive agents. The prepared blue ceramic ink was stably jetted and formed a sphere-shaped droplet from an ink-jet printer.