• Journal of Engineering Education Research
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• v.21 no.6
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• pp.35-43
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• 2018

In many universities, the Capstone Design course aims to educate creativity, teamwork and leadership, and ultimately aims to cultivate practitioners with practical ability required in the industry. Since the introduction of capstone design as a regular course, it has spread not only to engineering but also to the humanities and social sciences. A typical capstone design is usually carried out within a limited range of schedules and budgets within the scope of a major and a subject. In the case of a special-purpose capstone design, it is necessary to find out excellent items aiming at start-up and commercialization at an early stage, It contributes to the achievement of international convention participation, start-up and commercialization. The teaching styles of capstone design such as multidisciplinary capstone design, fusion capstone design, and global capstone design are developed and operated in various ways. Depending on each type, objectives, curriculum, scope of participation, operation method, performance and so on. In the case of capstone design, it is contributing to increase the achievements such as participation in international conventions, establishment of business and commercialization by early detection of excellent items aiming at start-up and commercialization, development and establishment of support process. Technological and Humanities Convergence Capstone Design Moel is named as the process of designing a four-level idea called "Idea Factory-based Technology-Humannities Fusion Capstone Design Process", and it is used to generate ideas, elaborate ideas, advanced ideas, and commercialization.

• Journal of the Korea Society for Simulation
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• v.28 no.1
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• pp.109-115
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• 2019

The probability of lethality of personnel targets inside a room is a key issue at assessing effectiveness of a weapon system. In this study, the minimum charge weight to achieve 100% lethality of personnel targets inside a box-type room is proposed at each side length of a base of a room. A fast running blast wave model is used to simulate the pressure-time histories of the blast generated by an internal explosion inside a room, and Axelsson SP method is used to evaluate the lethality of personnel targets under the blast. 176 different internal explosion scenarios are simulated for cases of TNT weights ranging from 20kg to 170kg inside a room whose square base has a side length ranging from 5m to 15m. A linear model and a charge-density model were developed to predict the minimum charge weight to achieve 100% lethality inside a room given a length of a base of a room.

• Entomological Research
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• v.48 no.5
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• pp.390-399
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• 2018

In order to precisely assess gene expression levels, the suitable internal reference genes must be served to quantify real-time reverse transcription polymerase chain reaction (RT-qPCR) data. For armyworm, Mythimna separata, which reference genes are suitable for assessing the level of transcriptional expression of target genes have yet to be explored. In this study, eight common reference genes, including ${\beta}$-actin (${\beta}$-ACT), 18 s ribosomal (18S), 28S ribosomal (28S), glyceraldehyde-3-phosphate (GAPDH), elongation fator-alpha ($EF1{\alpha}$), TATA box binding protein (TBP), ribosomal protein L7 (RPL7), and alpha-tubulin (${\alpha}$-TUB) that in different developmental stages, tissues and insecticide treatments of M. separata were evaluated. To further explore whether these genes were suitable to serve as endogenous controls, three software-based approaches (geNorm, BestKeeper, and NormFinder), the delta Ct method, and one web-based comprehensive tool (RefFinder) were employed to analyze and rank the tested genes. The optimal number of reference genes was determined using the geNorm program, and the suitability of particular reference genes was empirically validated according to normalized HSP70, and MsepCYP321A10 gene expression data. We found that the most suitable reference genes for the different experimental conditions. For developmental stages, 28S/RPL7 were the optimal reference genes, both $RPL7/EF1{\alpha}$ were suitable for experiments of different tissues, whereas for insecticide treatments, $28S/{\alpha}-TUB$ were suitable for normalizations of expression data. In addition, $28S/{\alpha}-TUB$ were the suitable reference genes because they have the most stable expression among different developmental stages, tissues and insecticide treatments. Our work is the first report on reference gene selection in M. separata, and might serve as a precedent for future gene expression studies.

• Journal of the Korea Institute of Information Security & Cryptology
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• v.21 no.5
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• pp.47-58
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• 2011

Recently, there are several technologies for protecting information in the lightweight device, One of them, the AES[1] algorithm and CRT mode, is used for numerous services(e,g, OMA DRM, VoIP, IPTV) as encryption technique for preserving confidentiality. Although it is possible that the AES algorithm CRT mode can parallel process transmitting data, IPTV Set-top Box or Mobile Device that uses these streaming service has limited computation-ability. So optimizing crypto algorithm and enhancing its efficiency for those environment have become an important issue. In this paper, we propose implementation method that can improve efficiency of the AES-CRT Mode by improving algorithm logics. Moreover, we prove the performance of our proposal on the mobile device which has limited capability.

• Steel and Composite Structures
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• v.39 no.1
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• pp.65-80
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• 2021

Irregularities of a building in plan and elevation, which results in the change in stiffness on different floors highly affect the seismic performance and resistance of a structure. This study motivated to investigate the seismic responses of high-rise steel-frame buildings of twelve stories with various stiffness irregularities. The building has five spans of 3200 mm distance in both X- and Z-directions in the plan. The design package SAP2000 was adopted for the design of beams and columns and resulted in the profile IPE500 for the beams of all floors and box sections for columns. The column cross-section dimensions vary concerning the number of the story; one to three: 0.50×0.50×0.05m, four to seven: 0.45×0.45×0.05 m, and eight to twelve: 0.40×0.40×0.05 m. Real recorded ground accelerations obtained from the Vrancea earthquake in Romania together with dead and live loads corresponding to each story were considered for the applied load. The model was validated by comparing the results of the current method and literature considering a three-bay steel moment-resisting frame of eight-story height subject to seismic load. To investigate the seismic performance of the buildings, the time-history analysis was performed using ABAQUS. Deformed shapes corresponding to negative and positive peaks were provided followed by the story drifts and fragility curves which were used to examine the probability of collapse of the building. From the results, it was concluded that regular buildings provided a seismic performance much better than irregular buildings. Furthermore, it was observed that building with torsional irregularity was more vulnerable to seismic failure.

• Journal of Korean Physical Therapy Science
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• v.28 no.3
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• pp.11-29
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• 2021

Background: The purpose of this study is to investigate the effects of virtual reality on gait, balance, and upper extremity functions compared to other independent variables or no variables. Additionally, the possibility of virtual reality for stroke patients was discussed. Design: Meta-analysis. Methods: The search for this study was a search term that combined stroke, virtual reality, and training, and the electronic search was conducted through EMBASE, MEDLINE, and Cochrane Library. As a result of the search, 21 studies satisfying the selection criteria of the target study were confirmed as the final analysis target. This study consisted of 21 randomized experimental studies and 21 randomized controlled trials, and the total number of participants was 642. [Experimental group (n=314), control group (n=328); total 642]. As a result of the study, upper extremity function was assessed using a box and block test, a modified Ashworth scale, and a scale including range of motion. The balance was evaluated by the berg balance scale. Gait was a Timed Up and Go test (TUG), stride length, and gait function. Scales including a walking rate scale were evaluated. The effect size for the intervention of the analytical study was meta-analyzed with the RevMan 5.3.3 program of the Cochrane library. Results: The results of the study showed that the function of walking was statistically significant. Balance showed statistically significant results. The upper extremity function showed no statistically significant results. Conclusion: Through this rehabilitation treatment by applying virtual reality environment to the rehabilitation of stroke patients in the future can be proposed as an effective intervention method for the balance and gait function of stroke patients.

• Journal of Microbiology and Biotechnology
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• v.32 no.7
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• pp.892-901
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• 2022

The rising demand for carotenoids can be met by microbial biosynthesis as a promising alternative to chemical synthesis and plant extraction. Several species of lactic acid bacteria (LAB) specifically produce C₃₀ carotenoids and offer the added probiotic benefit of improved gut health and protection against chronic conditions. In this study, the recently characterized Lactiplantibacillus plantarum subsp. plantarum KCCP11226^T produced the rare C₃₀ carotenoid, 4,4'-diaponeurosporene, and its yield was optimized for industrial production. The one-factor-at-a-time (OFAT) method was used to screen carbon and nitrogen sources, while the abiotic stresses of temperature, pH, and salinity, were evaluated for their effects on 4,4'-diaponeurosporene production. Lactose and beef extract were ideal for optimal carotenoid production at 25℃ incubation in pH 7.0 medium with no salt. The main factors influencing 4,4'-diaponeurosporene yields, namely lactose level, beef extract concentration and initial pH, were enhanced using the Box-Behnken design under response surface methodology (RSM). Compared to commercial MRS medium, there was a 3.3-fold increase in carotenoid production in the optimized conditions of 15% lactose, 8.3% beef extract and initial pH of 6.9, producing a 4,4'-diaponeurosporene concentration of 0.033 A₄₇₀/ml. To substantiate upscaling for industrial application, the optimal aeration rate in a 5 L fermentor was 0.3 vvm. This resulted in a further 3.8-fold increase in 4,4'-diaponeurosporene production, with a concentration of 0.042 A₄₇₀/ml, compared to the flask-scale cultivation in commercial MRS medium. The present work confirms the optimization and scale-up feasibility of enhanced 4,4'-diaponeurosporene production by L. plantarum subsp. plantarum KCCP11226^T.

• Journal of Korea Entertainment Industry Association
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• v.14 no.4
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• pp.145-153
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• 2020

In the rapidly changing era of the fourth industry, big data is being used in various fields. In recent years, the use of big data has been rapidly applied to overall cultural and artistic contents, and among them, the use of big data is essential as a film genre with a lot of capital. This research method is analyzed as the film , which won the Palme d'Or Prize of the 72nd Cannes Film Festival in 2019 and the works and directors' award at the Academy Awards. The analyzed value predicts the film's performance through opinion mining, which gives the value of the change and sensitivity of each data cycle, and extracts the utilization index and topic keywords of SNS such as Facebook and Twitter to reflect the audience's interest. Identify the factors. As such, if model performance and model development can be predicted through model analysis of film performance using big data, the efficiency of the film production process will be maximized while the risk of production cost and the risk of film failure will be minimized.

• Land and Housing Review
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• v.14 no.1
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• pp.67-82
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• 2023

Using the Artificial Neural Network model and Binary Logistic Regression model, this study investigates influence factors on the quality of life in terms of housing environment during the COVID-19 in Seoul. The results show that the lower the satisfaction level of housing policy, the lower the quality of life in the employment field and the lower the quality of residential field. On the other hand, permanent workers and self-employed respondents have experienced improvement in residential quality during the pandemic. A limitation of this study is associated with disentangling the causal relationship using the 'black box' characteristics of ANN method.

• Animal Bioscience
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• v.36 no.2
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• pp.295-306
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• 2023

Objective: Inhibiting the p38 mitogen-activated protein kinase (MAPK) signaling pathway delays differentiation and increases proliferation of muscle stem cells in most species. Here, we aimed to investigate the effect of p38 inhibitor (p38i) treatment on the proliferation and differentiation of chicken muscle stem cells. Methods: Chicken muscle stem cells were collected from the muscle tissues of Hy-line Brown chicken embryos at embryonic day 18, then isolated by the preplating method. Cells were cultured for 4 days in growth medium supplemented with dimethyl sulfoxide or 1, 10, 20 μM of p38i, then subcultured for up to 4 passages. Differentiation was induced for 3 days with differentiation medium. Each treatment was replicated 3 times. Results: The proliferation and mRNA expression of paired box 7 gene and myogenic factor 5 gene, as well as the mRNA expression of myogenic differentiation marker gene myogenin were significantly higher in p38i-treated cultures than in control (p<0.05), but immunofluorescence staining and mRNA expression of myosin heavy chain (MHC) were not significantly different between the two groups. Oil red O staining of accumulated lipid droplets in differentiated cell cultures revealed a higher lipid density in p38i-treated cultures than in control; however, the expression of the adipogenic marker gene peroxisome proliferator activated receptor gamma was not significantly different between the two groups. Conclusion: p38 inhibition in chicken muscle stem cells improves cell proliferation, but the effects on myogenic differentiation and lipid accumulation require additional analysis. Further studies are needed on the chicken p38-MAPK pathway to understand the muscle and fat development mechanism.