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The Effect of Dopaminergic Activity on Aldosterone Secretion in Edematous State (Dopaminergic Activity가 부종상태에서 혈청 Aldosterone 분비에 미치는영향)

  • Han, Bong-Heon;Ro, Heung-Kyu
    • The Korean Journal of Nuclear Medicine
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    • v.19 no.2
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    • pp.69-79
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    • 1985
  • To evaluate the effect of dopaminergic activity on aldosterone secretion, the plasma renin activity, serum cortisol and aldosterone were measured by radioimmunoassay in 6 normal controls and 12 patients who had hyponatremia and generalized edema or ascites with possible condition with secondary aldosteronism before and after(15, 30, and 60 min) 15 mg of metoclopramide by iv bolus injection and same method with 500 mg of L-dopa by per oral in 6 normal controls and 12 patients with edema ascites. The result were as follows; 1) The basal level of PRA was higher in patients rather than normal controls but PRA was not influenced by MC or L-dopa administration on both normal controls and patients group. 2) The serum cortisol level was significantly elevated at 30 min after MC injection compared with basal level in normal controls but no significant change was noted in patients group. After L-dopa administration the serum cortisol level was not changed in both normal controls and patients group. 3) The serum aldosterone level was significantly elevated in 15, 30 and 60 min after MC injection in normal controls, and there also same tendency of aldosterone secretion was noticed in patients group. On the other hands, there was no changes in aldosterone level in both normal controls and patients group with L-dopa administration. Above result means that MC stimulate aldosterone secretion by dopaminergic antagonist and aldosterone secretion in normal subject is controlled by maximal tonic dopaminergic inhibition. In edematous patients, however, both of the dopaminergic inhibitory and stimulating effect of PRA, ACTH etc on the aldosterone secretion seems to be variable.

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SLA (Service Level Agreement) Metrics in IT Operation Outsourcing (정보체계 운영 아웃소싱에 있어서의 서비스 수준 측정 메트릭)

  • 김용수
    • Journal of the Korea Society of Computer and Information
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    • v.9 no.2
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    • pp.69-79
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    • 2004
  • For the successful IT operation outsourcing there need appropriate metrics on which both of the service clients and provider agree. The metrics are used to set up the service level objectives, which are manifested in the service level agreement with price. A study of metrics is necessary for the following reasons: First, most of the metrics used today were introduced in the early years of computers and are not satisfactory to both of the service providers and clients. Second, metrics represent the performance of system components but not end-user satisfaction. Third, because the service provider leads the outsourcing agreement, the objectives are specified more favorable to the provider. The objectives should be based on metrics that both sides fully understand and agree on.

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Value orientation and the relationship between nurse′s role perception and patient′s expectation on selected routine nursing activities (간호원의 역할인식과 환자의 기대 -기본 간호역할의 가치의식을 중심으로-)

  • 한윤복;김순자;이인자
    • Journal of Korean Academy of Nursing
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    • v.4 no.2
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    • pp.144-158
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    • 1974
  • This study was undertaken in an attempt to; 1) measure value orientation of nursing activities, 2) identify the relationship between nurse's role perception and patient's expectation, and 3) evaluate the pattern of nursing education and nursing service administration. 203 hospitalized adults and 203 professional nurses from 11 general hospitals in Seoul during the period of July to December 1973 were tested according to questionnaire based on 4 categories of clinical nursing activities, 1) physical care, 2) observation and control, 3) psycho-social care and 4) therapeutic measures. Results of the study are as follows: 1. Nurses were more concerned than patients in the physical care category. Significant difference was revealed by p<.01 level (t=2.800). Mean value score of nurses was average (2.84), and mean value score of patients was relative' y low (2.49). None of the physical care category questionnaire items were over 3.5. 2. Respondents from hospitals of total care system revealed significant difference in the physical care category by P〈.025 level. (t=2.242). Mean value score of both group were average level (nurse 2.90, patient 2.53), nurses showed higher concern. 3. Difference between nurse's role perception and patient's expectation in observation and control category was revealed non- significance by p〉0.05. level (t=1.238). Mean value score of both group revealed relatively high (nurse=3.44, patient 3.19). 4. Difference between nurse's role perception and patient〉expectation in psycho-social cart category revealed non- significance by p〉.05 level (t=0.758), Mean value score of both group revealed average level (nurse =2.71, patient =2.53), 5. Non- significant difference was noted between B. S. N. and diploma nurse's role perception in the psycho- social care category by p> 0.1 level (t=0.316). 4. Difference between nurse's role perception and patient's expectation in the rapeutic me assures category revealed non- significance by p〉0.05 level) t=0.503). Horses showed high concern by mean value score 3.56 level and patients relatively high by 3.41. All items of this category revealed very high or relatively high value score.

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An Experimental study on the effects of Chihyosan and Chihyosangamibang on the Anti-allergic effect and Pulmonary Function of $O_3$ intoxicated Rat (치효산(治效散) 및 치효산가미방(治效散加味方)이 항(抗)알레르기 및 폐손상(肺損傷)에 미치는 영향(影響))

  • Shin Weon-Kyoo;Jeong Gyu-Mahn
    • The Journal of Pediatrics of Korean Medicine
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    • v.12 no.1
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    • pp.231-256
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    • 1998
  • Experimental studies were done to research the clinical effects of Chihyosan and Chihyosangamibang on the Anti-allergic effect and pulmonary function of $O_3$ intoxicated Rats. Anti-allergic effect experiment consisted of vascular permeability responses to intradermal histamine and serotonin, 48hrs homologous passive cutaneous anaphylaxis provoked by the IgE-like antibody against egg white albumin, and delayed type hypersensitivity responses to Picryl Chloride and SRBC. Pulmonary function of $O_3$ intoxicated Rats experiment consisted of lung TBA value, water Contents of the lung, oxygen consumption time, and arterial blood $pCO_2,\;pO_2,\;HCO_3^-$, pH level. The results obtained as follows; 1. In the effects of Chihyosan and Chihyosangamibang on vascular permeability responses to intradermal histamine, both of chihyosan and Chihyosangamibang group revealed significant effect. 2. In the effects of Chihyosan and Chihyosangamibang on vascular permeability responses to intradermal serotonin, both of chihyosan and Chihyosangamibang group revealed significant effect. 3. In the 48hrs homologous passive cutaneous anaphylaxis provoked by the IgE-like antibody against egg white albumin, Chihyosan groups revealed significant effect, but Chihyosangamibang groups revealed none significant effect. 4. In the delayed type hypersensitivity responses to Picryl Chloride, Chihyosan and Chihyosangamibang groups revealed none significant effect. 5. In the delayed type hypersensitivity responses to. SRBC, Chihyosan revealed none significant effect, but Chihyosankamibang revealed significant effect. 6. Both of Chihyosan and Chihyosangamibang groups revealed significant effect on decrease of the lung TBA value of lung. 7. Both of Chihyosan and Chihyosangamibang groups revealed significant effect on decrease of the water contents of right and left lung. 8. Both of Chihyosan and Chihyosangamibang groups revealed significant effect on decrease of oxygen consumption time. 9. In the decrease effect of arterial blood $pCO_2$ level, both of Chihyosan and Chihyosangamibang groups revealed none significant effect. 10. In the increase effect of arterial blood $pO_2$ level, both of Chihyosan and Chihyosangamibang groups revealed none significant effect. 1. In the decrease effect of arterial blood $HCO_3^-$ level, both of Chihyosan and Chihyosangamibang groups revealed significant effect. 12. In the increase of arterial blood pH level, Chihyosangamibang groups revealed none significant effect, but Chihyosan groups revealed significant effect. According to above stated results, both of Chihyosan and Chihyosangamibang are very usefully for treatment of cough, asthma, chronic obstructive pulmonary diseases and allergic pulmonary diseases.

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A multi-level analysis of the individual and team-level effects on psychological capital (긍정심리자본에 영향을 미치는 개인수준과 팀 수준 요인에 관한 연구)

  • Hahn, Ju Hee;Lim, Kyu Hyuk
    • Knowledge Management Research
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    • v.13 no.5
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    • pp.91-111
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    • 2012
  • The purpose of this study is to investigate the effect of person-organization fit(PO fit) and person-job fit(PJ fit) on positive psychological capital at both team-level and individual-level. Present study intends to confirm the effectiveness through theoretical considerations and empirical analysis of positive organizational behaviors. This is expected to strengthen the basis of positive organizational behavior studies and provide the foundation to integrate positive organizational behavior to the actual organization. In order to test the hypotheses, the data were collected from multiple domestic organizations and composed 47 team-level and 244 individual-level data. For the analysis, hierarchical linear modelling(HLM) were conducted. The results of this study are as follows. PO fit and PJ fit had significant relationships with positive psychological capital at both team-level and individual-level. Also, in the relationship between the attitudes and behaviors of the members and positive psychological capital, the positive psychological capital was found to have significant effect on affective commitment and organizational citizen behaviors. The implications of this study according to the results as follows. Positive relationships of psychological capital with the antecedents and consequences variables, it is necessary for the management to magnify the strength of members in the actual operation at the organization level. Such the management of positive psychological capital can be suggested as a new approach method for achievement of the organization's goals and visions.

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Stress and Coping among Parents of Mentally Retarded Children in the Kyoung-in area (경인 지역의 정신 지체아 부모의 스트레스와 대응)

  • 구현영
    • Journal of Korean Academy of Nursing
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    • v.25 no.4
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    • pp.668-680
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    • 1995
  • The purpose of this study was to contribute to family nursing for reducing stress and improving coping of the parents of mentally retarded children. Data were collected through self-reported questionnaires during a period of 2 months between November 1994 and January 1995 in the Kyoung-in area. The subjects consist of 180 parents (90 mothers and 90 fathers) of mentally retarded children attending schools for the handicapped and 186 parents (93 mothers and 93 fathers) of normal children. The levels of general stress and of parental role stress were measured with the General stress scale and the Parental role stress scale, respectively, while the Coping scale was adopted to measure the level of coping. The data were analyzed by using Chi-square test. fisher's exact test, Repeated masured ANOVA, oneway ANOVA and Scheffe comparison test. The results were as follows ; 1. The level of general stress was significantly higher in the mothers and the fathers of the men-tally retarded than in the respective parents of the normal. Of the parents, the mothers experienced significantly greater level of general stress than the fathers did in both groups of the retarded and of the normal. 2. As for the parental role stress, the mothers and the fathers of the mentally retarded experienced significantly greater stress than respective parents of normal children did. In particular, the stress was significantly higher in the mothers than the fathers of these children in both groups. The difference in the levels of parental role stress experienced by mothers and by fathers was significantly bigger among those of the mentally retarded tnan among those of normal children. 3. No significant difference in the level of coping was observed between the mothers of both groups and the fathers of both groups. By contrast, the fathers revealed significantly greater scores in coping than the mothers in both groups. 4. General stress experienced by the fathers of the mentally retarded was different by health status, satisfaction with spouses, and the supports from their spouses. Health status, satisfaction with spouses, and monthly income Influenced parental role stress experienced by those fathers. Their level of coping was associated with their satis-faction with spouses and family life. 5. Of the mothers of the mentally retarded, the level of general stress was different by their health status, while parental role stress was related to the satisfaction with their spouses and the child's age. The level of coping among the mothers was different by the supports from their spouses. The above findings indicate that those parents of the mentally retarded did not take more coping strategies than those of the normal did, despite greater stress experienced among themselves. Hence, nursing intervention for managing stress should be given to those parents including fathers of mentally retarded children. Mothers of the mentally retarded, in particular, should receive high priority in planning nursing care, since they experience greater levels of both general stress and parental role stress than their spouses, which is most likey due to primary responsibility in child rearing given to them at home.

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Evaluation of a Nutrition Model in Predicting Performance of Vietnamese Cattle

  • Parsons, David;Van, Nguyen Huu;Malau-Aduli, Aduli E.O.;Ba, Nguyen Xuan;Phung, Le Dinh;Lane, Peter A.;Ngoan, Le Duc;Tedeschi, Luis O.
    • Asian-Australasian Journal of Animal Sciences
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    • v.25 no.9
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    • pp.1237-1247
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    • 2012
  • The objective of this study was to evaluate the predictions of dry matter intake (DMI) and average daily gain (ADG) of Vietnamese Yellow (Vang) purebred and crossbred (Vang with Red Sindhi or Brahman) bulls fed under Vietnamese conditions using two levels of solution (1 and 2) of the large ruminant nutrition system (LRNS) model. Animal information and feed chemical characterization were obtained from five studies. The initial mean body weight (BW) of the animals was 186, with standard deviation ${\pm}33.2$ kg. Animals were fed ad libitum commonly available feedstuffs, including cassava powder, corn grain, Napier grass, rice straw and bran, and minerals and vitamins, for 50 to 80 d. Adequacy of the predictions was assessed with the Model Evaluation System using the root of mean square error of prediction (RMSEP), accuracy (Cb), coefficient of determination ($r^2$), and mean bias (MB). When all treatment means were used, both levels of solution predicted DMI similarly with low precision ($r^2$ of 0.389 and 0.45 for level 1 and 2, respectively) and medium accuracy (Cb of 0.827 and 0.859, respectively). The LRNS clearly over-predicted the intake of one study. When this study was removed from the comparison, the precision and accuracy considerably increased for the level 1 solution. Metabolisable protein was limiting ADG for more than 68% of the treatment averages. Both levels differed regarding precision and accuracy. While level 1 solution had the least MB compared with level 2 (0.058 and 0.159 kg/d, respectively), the precision was greater for level 2 than level 1 (0.89 and 0.70, respectively). The accuracy (Cb) was similar between level 1 and level 2 (p = 0.8997; 0.977 and 0.871, respectively). The RMSEP indicated that both levels were on average under-or over-predicted by about 190 g/d, suggesting that even though the accuracy (Cb) was greater for level 1 compared to level 2, both levels are likely to wrongly predict ADG by the same amount. Our analyses indicated that the level 1 solution can predict DMI reasonably well for this type of animal, but it was not entirely clear if animals consumed at their voluntary intake and/or if the roughness of the diet decreased DMI. A deficit of ruminally-undegradable protein and/or a lack of microbial protein may have limited the performance of these animals. Based on these evaluations, the LRNS level 1 solution may be an alternative to predict animal performance when, under specific circumstances, the fractional degradation rates of the carbohydrate and protein fractions are not known.

The Effects of Using Science Notebooks in the Open Inquiry Activities by Cognitive Levels (인지 수준에 따른 자유 탐구 활동에서 과학 탐구 노트의 활용 효과)

  • Lee, Sang-Gyun
    • Journal of Korean Elementary Science Education
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    • v.30 no.2
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    • pp.242-254
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    • 2011
  • The purpose of this study was to understand the teaching effects according to the cognitive levels after conducting inquiry activities using science notebooks in the open inquiry activities of the elementary science class. The results of this study were as follow. first, students having the open inquiry activities using science notebooks showed improvement in scientific inquiry abilities in both groups with the low and high cognitive level. Second, regarding the changes of scientific attitudes, both groups with the low and high cognitive level exhibited improvement. According to the result of analyzing interaction between the cognitive level and class treatment on the effects for scientific inquiry abilities and scientific attitudes, there was no difference by the cognitive level. And the use of science notebooks in open inquiry activities had effects on improving scientific inquiry abilities and scientific attitudes regardless of the cognitive level.

A Study on the Polychlorinated Biphenyls in Human Blood (혈중 PCB 함량에 관한 조사)

  • 김돈균;정갑열;이수일;황인철
    • Journal of Korean Society for Atmospheric Environment
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    • v.1 no.1
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    • pp.9-15
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    • 1985
  • For the purpose of obtaining the index that represents the contaminated status due to polychlorinated biphenyls (PCB) in the human body, the authors investigated the contents of PCB in the plasma of 183 subjects who were not exposured to the massive amount of PCB occupationaly in the past. The obtained results were as follows; 1. The mean contents of PCB in plasma were 3.35 $\pm$ 1.48 ppb in male and 3.04 $\pm$ 1.06 ppb in female. $Cl_4$ and $Cl_3$ were the main isomers in both sexes. 2. The distribution of total-PCB by the age group was showed increasing tendency with the age in both sexes. 3. The tendency of freqyency distribution of total-PCB level were skewed to the higher level in malo and skewed to the lower level in female. 4. There was satistically significant interrelationship between age and total-PCB in plasma in both sexes.

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The Effects of the Essential Oil Fraction and the Fatty Acid Fraction of Panax Ginseng on the Lipid Metabolism (지질대사(脂質代謝)와 인삼지방산류(人蔘脂肪酸類) 및 정유(精油)에 관(關)한 연구(硏究))

  • Choi, Taik-Kyu;Hong, Sa-Ack
    • The Korean Journal of Pharmacology
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    • v.4 no.1 s.5
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    • pp.17-26
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    • 1968
  • The effects of the essential oil fraction and the fatty acid-fraction of the panax Ginseng on the various lipids (total cholesterol, phospholipid, triglyceride) in serum and liver tissues of the white rats were examined and observed after the administration of the fractions for eight weeks with the following results: 1. Serum total cholesterol level was slightly decreased in the group after giving the essential oil fraction four weeks, whereas the effects in the group after giving itfor eight weeks were increased. Phospholipid level was slightly elevated both in four weeks and in eight weeks, while triglyceride level was elevated after four weeks, whereas it showed nochange at all after eight weeks. In the liver tissues, the cholesterol content was slightly decreased after four weeks and remarkably decreased after the administration for eight week. Phospholipid increased after four week administration and then rather decreased after the eight week administration, while the triglyceride content decreased both in four weeks and in eight weeks. 2. In the group giving the fatty acid-fraction, serum total cholesterol level decreased after the four week administration and then returned to the pre-experiment mean after the eight-week administration, while phospholipid level increased after the four-week administration and then returned to the pre experiment mean. Triglyceride level increased after four week administration of the fraction and rather then decreased after eight weeks. In the liver tissues, total cholesterol content decreased both after four weeks and after eight weeks, while phospholipid level also decreased from four weeks through eight weeks, whereas triglyceride level increased after four weeks, and showed rather decreasing tendency after the eight-week administration.

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