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Prospective Memory Loss and Related White Matter Changes in Patients with Amnestic Mild Cognitive Impairment

  • Yoon, Bora;Ryu, Sun Young;Yoon, Soo Jin
    • Dementia and Neurocognitive Disorders
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    • v.17 no.3
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    • pp.120-129
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    • 2018
  • Background and Purpose: Prospective memory (PM) has a known relationship with frontal function, and PM decline has been observed in amnestic mild cognitive impairment (aMCI). Cerebral small vessel disease, as evidenced by white matter hyperintensities (WMHs), is linked to frontal dysfunction. This study was undertaken to evaluate the relationship between PM decline and WMHs in patients with aMCI. Methods: Of 74 enrollees with aMCI, 69 completed this prospective study. We compared total scores and sub-scores of the Prospective and Retrospective Memory Questionnaire (PRMQ) administered at baseline and 3 months later, stratifying patients by degree of WMHs. Results: A significant decline was seen in PRMQ total scores and PM scores at the 3-month mark in patients with moderate (vs. mild) degrees of WMHs ($-2.8{\pm}7.2$ vs. $0.2{\pm}7.1$; p=0.032). In addition, patients with moderate (vs. mild) degrees of deep WMHs (DWMHs) showed greater PM decline, whereas PM loss in patients with mild, moderate, or severe degrees of periventricular WMHs (PVWMHs) did not differ significantly. Conclusions: Findings of this study indicate that the burden of WMHs is consistently implicated in PM deterioration experienced by patients with aMCI, and signifies greater PM decline, especially in instances of extensive DWMHs. Greater attention to the change of PM is therefore needed in aMCI patients with WMHs.

Molecular Phylogeny and Morphology Reveal the Underestimated Diversity of Mortierella (Mortierellales) in Korea

  • Lee, Jae-Sung;Nam, Bora;Lee, Hyang Burm;Choi, Young-Joon
    • The Korean Journal of Mycology
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    • v.46 no.4
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    • pp.375-382
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    • 2018
  • Members of the genus Mortierella (Mortierellales) are filamentous fungi, which are found on nearly all substrates, but more frequently in soil. Till date, 7 species of Mortierella have been reported in Korea, but being a ubiquitous group with high species diversity in temperate zones, this number is still low. During a survey of fungal biodiversity in Korea, we collected many isolates of Mortierella, and through morphological and molecular phylogenetic analyses, identified them to be 3 previously unrecorded species, namely, M. chienii, M. epicladia, and M. gamsii. A total of 10 Mortierella species in Korea, including the 3 species reported in the present study, are widely distributed in 5 out of 7 phylogenetic groups of this genus. This indicates that the diversity of Mortierella was so far underestimated in Korea. Multi-locus sequence analysis is required to provide a more reliable backbone for some uncertain phylogenetic groupings and to more clearly define a species of Mortierella, which would encourage deeper research in the diversity and ecological roles of Mortierella and allied genera.

Transition of the Kazakh Writing System from Cyrillic to Latin

  • Kim, Bora
    • International Journal of Advanced Culture Technology
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    • v.6 no.4
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    • pp.12-19
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    • 2018
  • This article aims to discuss the transition of the Kazakh writing system from Cyrillic to Latin. First, the study investigates the relationship between the Kazakh Cyrillic alphabet and phonology, in order to linguistically evaluate the efficiency of the writing system. Second, the process of determining the Kazakh Latin alphabet is discussed in terms of the Kazakh phonological system. Third, the factors that determined the Latin alphabet of Kazakh language are analyzed. In Kazakh, the phonemic system is subject to controversy among linguists, but it can be said that the phonological system basically follows the one-to-one correspondence to the Russian and Kazakh phonemes. As for the depth of orthographies, Kazakh Cyrillic writing system is not based on the shallow orthographies, so it incorporates morphophonemic information to make skilled readers understand easier. The political and social aspects are considered as a cause of the alphabet change. Although there are studies suggesting the conversion of the writing system is caused by the extrinsic factors rather than the intrinsic factors, the five criteria of Smalley (1964), which compromise the intrinsic and extrinsic factors, are also persuasive. The five factors are 1) Maximum motivation for the learner, 2) Maximum representation of speech, 3) Maximum ease of learning, 4) Maximum transfer, 5) Maximum ease of reproduction.

Characterization of Achlya americana and A. bisexualis (Saprolegniales, Oomycota) Isolated from Freshwater Environments in Korea

  • Choi, Young-Joon;Lee, Seo Hee;Nguyen, Thuong T.T.;Nam, Bora;Lee, Hyang Burm
    • Mycobiology
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    • v.47 no.2
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    • pp.135-142
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    • 2019
  • Many members of the Saprolegniales (Oomycete) cause mycoses and disorders of fishes, of which Achlya and Saprolegnia are most ubiquitous genera worldwide. During a survey of the diversity of freshwater oomycetes in Korea, we collected seven isolates of Achlya, for which morphological and molecular phylogenetic analyses enabled them to identify as Achlya americana and Achlya bisexualis. In Korea, only a species of Achlya, A. prolifera, has been previously found to cause seedling rot on rice (Oryza sativa), but none of the two species have been reported yet. Importantly, A. bisexualis was isolated from a live fish, namely rice fish (Oryzias sinensis), as well as freshwater, and this is the first report of Achlya-causing mycoses on freshwater fishes in Korea. The presence of A. americana and A. bisexualis on live fish in Korea should be closely monitored, as considering the well-known broad infectivity of these species it has the potential to cause an important emerging disease on aquaculture industry.

Effect of Synthesis Method and Melamine Content of Melamine-Urea-Formaldehyde Resins on Bond-Line Features in Plywood

  • LUBIS, Muhammad Adly Rahandi;JEONG, Bora;PARK, Byung-Dae;LEE, Sang-Min;KANG, Eun-Chang
    • Journal of the Korean Wood Science and Technology
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    • v.47 no.5
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    • pp.579-586
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    • 2019
  • This work examined effects of the synthesis method and melamine content of melamine-urea-formaldehyde (MUF) resins on the bond-line features (i.e. resin penetration and bond-line thickness) in plywood. Two synthesis methods (MUF-A and MUF-B) and three melamine contents (5, 10, and 20%) were employed to prepare MUF resins. The MUF-A resins at three melamine contents were prepared by a simultaneous reaction of melamine, urea, and formaldehyde, while the MFU-B resins were prepared by reacting melamine at the same levels with formaldehyde followed by urea. The results showed that higher melamine content increased the viscosity of MUF-A and MUF-B resins. The resin penetration of MUF-A resins decreased by 48% while those of MUF-B resins increased by 16% at 20% melamine content. As a result, the MUF-A resins had greater bond-line thickness than those of MUF-B resins as the melamine content increased. The MUF-B resins resulted in thinner bond-line and greater resin penetration compared to those of MUF-A resins. The results suggested that MUF-B resins prepared with 20% melamine content had a proper combination of resin penetration and bond-line thickness that could produce plywood panel with a better adhesion performance.

Walking behaviors for stroke survivors: comparison between straight line and curved path

  • Hwang, Wonjeong;Choi, Bora;Hwang, Sujin
    • Physical Therapy Rehabilitation Science
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    • v.8 no.3
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    • pp.141-145
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    • 2019
  • Objective: The purpose of this study was to compare walking conditions (straight line and curved path) on walking patterns in persons who had experienced hemiplegic stroke and to determine whether if they adapt their walking pattern and performances according to changes in environmental conditions. Design: Cross-sectional study. Methods: Forty-four hemiplegic stroke survivors participated in this study. This study measured walking performance in three different walking conditions, such as straight walking, the more-affected leg in the inner curve walking, and less-affected leg in the inner curve walking conditions, and a 2-dimentional gait analysis system was used as a primary measurement. This study also measured secondary clinical factors including the Timed Up-and-Go Test, the Trunk Impairment Scale, and the Dynamic Gait Index. Results: After analyzing, cadence and step length of the less-affected side, stride length in the more-affected side, and stride length in less-affected side were significantly different among the three different walking conditions in this study (p<0.05), but other temporospatial parameters were not significant. Cadence was the largest in the straight walking condition. Step length in the less-affected side, stride length in the more-affected side, and stride length in less-affected side were also the longest in the straight walking condition. Conclusions: The results of the study suggest that hemiplegic stroke survivors show walking adaptability according to changes in walking demands and conditions, and moreover, cadence and step and stride lengths were significantly different between straight and curved walking conditions.

Pilot scale membrane separation of plating wastewater by nanofiltration and reverse osmosis

  • Jung, Jaehyun;Shin, Bora;Lee, Jae Woo;Park, Ki Young;Won, Seyeon;Cho, Jinwoo
    • Membrane and Water Treatment
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    • v.10 no.3
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    • pp.239-244
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    • 2019
  • Plating wastewater containing various heavy metals can be produced by several industries. Specifically, we focused on the removal of copper (Cu2+) and nickel (Ni+) ions from the plating wastewater because all these ions are strictly regulated when discharged into watershed in Korea. The application of both nanofiltration (NF) and reverse osmosis (RO) technologies for the treatment of wastewater containing copper and nickel ions to reduce fresh water consumption and environmental degradation was investigated. In this work, the removal of copper (Cu2+) and nickel (Ni+) ions from synthetic water was studied on pilot scale remove by before using two commercial nanofiltration (NF) and reverse osmosis(RO) spiral-wound membrane modules (NE2521-90 and RE2521-FEN by Toray Chemical). The influence of main operating parameters such as feed concentration on the heavy metals rejection and permeate flux of both membranes, was investigated. Synthetic plating wastewater samples containing copper ($Cu^{2+}$) and nickel ($Ni^{2+}$) ions at various concentrations(1, 20, 100, 400 mg/L) were prepared and subjected to treatment by NF and RO in the pilot plant. The results showed that NF, RO process, with 98% and 99% removal for copper and nickel, respectively, could achieve high removal efficiency of the heavy metals.

Influence of age at complementary food introduction on the development of asthma and atopic dermatitis in Korean children aged 1-3 years

  • Lee, Jihyun;Shin, Meeyong;Lee, Bora
    • Clinical and Experimental Pediatrics
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    • v.64 no.8
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    • pp.408-414
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    • 2021
  • Background: Complementary food in infancy is necessary for human growth, neurodevelopment, and health. However, the role of allergen consumption in early infancy and its effects on the development of food allergy or tolerance remain unclear. Purpose: To investigate the influence of age at the time of complementary food introduction on the development of asthma and atopic dermatitis in Korean children aged 1-3 years. Methods: We combined data from the Korea National Health and Nutrition Examination Survey collected from 2010 to 2014 and analyzed 1619 children aged 1-3 years who were included in the survey. Multivariate regression analysis was used to identify associations among type of feeding, age at the time of complementary food introduction, and doctor-diagnosed atopic dermatitis and asthma. Results: Age at the time of complementary food introduction was not significantly associated with doctor-diagnosed atopic dermatitis and asthma in children aged 1-3 years. In the univariate analysis, children with asthma showed higher water and sodium intake levels than nonasthmatic children. However, this relationship was not significant in the multivariate regression analysis. Conclusion: The present study revealed no statistically significant relationship between age at the time of complementary food introduction and the risk of atopic dermatitis and asthma in young Korean children. A national prospective study is needed to clarify the influence of age at the time of complementary food introduction on the development of allergic diseases.

Variation of Plant and Fruit Characteristics in Capsicum frutescens.

  • Ro, Na-young;Hur, Onsook;Lee, Jeaeun;Hwang, Aejin;Kim, Bitsam;Yi, JungYoon;Geum, Bora;Lee, Hosun;Noh, Jaejong;Rhee, Juhee
    • Proceedings of the Plant Resources Society of Korea Conference
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    • 2019.10a
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    • pp.38-38
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    • 2019
  • Among the 6500 accessions of the pepper germplasm which conserved at RDA Genebank, 319 accessions were investigated charateristics such as their growth habit, flowering and fruit shape in Capsicum frutescens. All accessions were characterized for their 14 qualitative and 16 quantitative characters. Results revealed that both qualitative and quantitative characters exhibited wide variation among the studied germplasm. The hypocotyl color, which investigated in juvenile stage, was divided in three types such as green, purple, and purple with green, and most of the accessions showed in purple. Flowering starts from 7 May, and most accessions were starting to flower from 27 May to 25 June. The fresh color of the mature pepper were red, yellow, orange, Etc. Fruit shape were mostly elongated, while exhibited ball shape and round shape were a few. The fresh weight of fruits ranged from 0.2 to 42.3, and the diameter of fruit showed from 4.2 to 45.1 mm, respectively. The phenotypic diversity exists in Capsicum frutescens. provide valuable information to improve agronomic traits in pepper breeding program.

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Outbreak of Cyclosporiasis in Korean Travelers Returning from Nepal

  • Ma, Da-Won;Lee, Myoung-Ro;Ku, Bora;Cho, Shin-Hyeong;Lee, Sang-Eun
    • Parasites, Hosts and Diseases
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    • v.58 no.5
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    • pp.589-592
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    • 2020
  • Cyclospora cayetanensis is an apicomplexan protozoan and is one of the most common pathogens causing chronic diarrhea worldwide. Eight stool samples with diarrheal symptom out of 18 Korean residents who traveled to Nepal were obtained, and examined for 25 enteropathogens including 16 bacterial species, 5 viral species, and 4 protozoans in stool samples as causative agents of water-borne and food-borne disease. Only C. cayetanensis was detected by nested PCR, and 3 PCR-positive samples were sequenced to confirm species identification. However, the oocysts of C. cayetanensis in fecal samples could not be detected by direct microscopy of the stained sample. As far as we know, this is the first report of a group infection with C. cayetanensis from a traveler visiting Nepal, and the second report of a traveler's diarrhea by C. cayetanensis imported in Korea.