• 한국산업보건학회지
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• 제20권3호
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• pp.156-167
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• 2010

To evaluate the effect of lead biomarkers including bone lead on neurobehavioral test in retired lead workers, 131 retired lead workers without any occupational exposure to organic solvent, mercury and arsenic were agreed to participate this study. For the control subjects 56 non-occupationally lead exposed subjects were recruited from same area of retired lead workers with consideration of demographic characteristics. The mean levels of blood and bone lead of retired lead workers were significantly higher than control group and there were significant correlation among other lead biomarkers. Compared with controls without occupational lead exposure, lead exposured subjects had worse performance on 10 tests out of 12 neurobehavioral tests, but only two tests(Purdue pegboard nondominant and both hand) showed statistical significance of differences. In multiple linear regression analysis of neurobehavioral tests with lead biomarkers and demographic and lifestyle variables, age was associated negatively with 11 neurobehavioral tests, whereas log-transformed ZPP was associated with Purdue pegboard(both hand) and Santa Ana manual dexterity(non-dominant hand). On the other hand, tibia lead was associated Pursuit aiming test(correct) and Purdue pegboard(dominant hand) and calcaneal lead was associated with Purdue pegboard(dominant hand). This study confirmed that among all relevant variables age was most significantly associated with the poor performance of neurobehavioral tests. The blood lead did not have any significant association with neurobehavioral tests, but tibia and calcaneal bone lead and blood ZPP showed significant association with a few tests even after more than mean 9 years from their retirements.

• Asian-Australasian Journal of Animal Sciences
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• 제25권9호
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• pp.1262-1268
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• 2012

The present investigation was designed to determine whether supplementation of different level of vitamin E for 12 months to arsenic exposed goats (50 ppm as sodium arsenite) affords protection against the blood hemato-biochemical parameters caused by the metalloid. A total of 24 crossbred (Alpine${\times}$Beetal) lactating goats were assigned randomly into 4 equal groups (control, $T_1$, $T_2$ and $T_3$) of 6 in each, on the basis of average body weight ($36.10{\pm}0.11$ kg) and milk yield ($1.61{\pm}0.04$ kg/d). The animals in $T_1$, $T_2$ and $T_3$ were given 50 ppm arsenic, while in $T_2$ and $T_3$, additionally; vitamin E at the rate of 100 IU and 150 IU/kg dry matter (DM) respectively was additionally supplemented for the period of 12 months. Hemoglobin (Hb), total leukocyte (TLC) and blood lymphocyte % were decreased (p<0.05) in arsenic fed groups and vitamin E supplementation in the experimental group showed a protective potential. Significant increases (p<0.05) in aspertate transaminase (AST) and alanine transaminase (ALT) activities among arsenic supplemented groups were recorded, however vitamin E supplementation at higher doses showed a protective effect (p<0.05) against AST but in the case of ALT no ameliorating effect was found in either of the doses. Plasma total protein was decreased (p>0.05) but creatinine level was periodically increased in all As supplemented groups and vitamin E supplementation did not produce any protective effect. It can be concluded that arsenic exposure resulted in varying degree of changes in hemato-biochemical parameters and activities of antioxidant enzymes in goats but concomitant treatment with Vitamin E is partially helpful in reducing the burden of arsenic induced effect.

• 문화기술의 융합
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• 제3권4호
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• pp.177-180
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• 2017

최근 전 세계적으로 노령화가 급속하게 진행됨에 따라 인체에 무해하고, 치료 시 부담이 적은 방법으로 Light(UV-LED 등)를 사용하는 연구가 지속적으로 진행되고 있다. 특히 일부 분야에서는 국한적으로 사용되는 것이 아니라, 피부과, 치과, 이비인후과 등 다양한 의료분야에 활용될 수 있다는 장점이 있어 대다수의 선진국에서는 이를 이용한 다양한 연구가 진행되고 있으나, 국내에서 의료용 Light를 활용한 치료법은 선진국 대비 매우 뒤처져 있는 상황이다. 따라서 본 논문에서는 의료용으로 사용될 수 있는 Light 모듈을 IoT 클라우든 기반 미들웨어 플랫폼 이용하여 효과적으로 제어함으로써 환자들에게 인체에 무해한 양질의 서비스를 제공할 수 있는 기술에 대하여 제안한다.

• Journal of Nutrition and Health
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• 제7권4호
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• pp.6-11
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• 1974

1. 시범(示範)과 비교부락간(比較部落間)의 영양실태(營養實態)는 별차(別差)가 없다. 따라서 위(胃)의 부담(負擔)을 줄이고 적은 양(量)으로 많은 영양가(營養價)를 얻기 위(濕)하여 곡류(穀類)나 채식위주(菜食爲主)의 부통적(博統的) 식생활(食生活)에서 빨리 탈피(脫皮)할 수 있는 광의(廣意)의 혼식(混食)으로 식생활(食生活)의 개선(改善)이 시급(時急)히 요망(要望)된다. 2. 구강(口腔)의 건강(健康)이 전신(全身)의 건강(健庸)과 직결(直結)된다고 할 수 있는 치아보건(齒牙保健)을 위(爲)하여 채유이외(菜誘以外)의 다른 식품군(食品群)에서 다량(多量)의 Ca섭취(攝取)를 꾀하도록 연구(硏究)와 노력(努力)이 있어야겠다. 특(特)히 임부(任婦)의 각성(覺醒)이 촉구된다. 3. 식후(食後) 3분내(分內)에 1분간(1分間)의 이닦는 운동(運動)을 반드시 1일(日) 3회(回) 할 수 있는 3 3 3 운동(運動)動의 습관(習慣)을 갖도륵 철저(徹底)한 주지(周知)가 있어야 하겠다.

• 대한가정학회지
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• 제40권11호
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• pp.193-205
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• 2002

To evaluate farmers' workload during harvesting grapes in summer, this study investigated farmers' physiological, psychological responses, work postures and thermal environment around in the field. This field study was conducted in the Anseong County of Kyonggi Province at the end of August. Five career farmers (1 male, 4 females) volunteered as subjects. Three of them were over their sixties. During harvesting grapes in the field, physiological responses were monitored continuously. 1. Air temperature (T/sub a/), air humidity(H/sub a/), black globe temperature(T/sub g/), air velocity and WBGT around the grape field were 26.9℃, 77.7%RH, 32.8℃, 0.08㎧ and 26.3℃, respectively. Because farmers started the harvesting task in early morning, thermal environments weren't conditions to give farmers severe heat strain. 2. The percentage of the work postures was larger in order of standing, walking, and bending one's back posture. Particularly, the percentage of standing posture with raising both arms above shoulder of two farmers was up to 29% and 61% of the total work duration. 3. Rectal temperature (T/sub re/), mean skin temperature (T/sub sk/), clothing microclimate temperature (T/sub cl/) on the chest and the back, heart rate (HR) and energy expenditure (EE) were 37.2℃, 33.1℃, 32.0℃, 32.4℃, 88bpm and 1.3 Kca1/㎡/min respectively. In the point of these physiological results, we evaluated that the harvesting task was a moderate work. 4. All farmers expressed‘hard, hot, humid and slightly uncomfortable’ at the end of works for each subjective questionnaire. The grape harvesting tasks were not evaluated as a very hard work in the point of physiological work standards. But we considered 1) inappropriate work posture (standing posture with raising both arms above shoulder) and 2) farmers' age as burden factors. These findings suggest that adding adequate protective clothing/equipments for farmers may contribute to maintain their body temperature within the normal range, stabilize HR and decrease psychological strain.

• 한국직업건강간호학회지
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• 제19권2호
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• pp.190-204
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• 2010

Purpose: This study was conducted to obtain the fundamental data on prevention and management of musculoskeletal symptoms, and to assess the prevalence, risk factors and job characteristics of musculoskeletal symptoms in hotel employees. Methods: The work sampling analysis was carried out by OWAS, and the prevalence was surveyed in term of NIOSH diagnostic criteria and work related risk factors on 263 hotel employees in Busan, Korea, using structured self-administered questionnaire from Jan. 20 to Feb. 26, 2010. The collected data were analysed by the SPSS 18.0. Results: 1) The prevailing rate of musculoskeletal symptoms by NIOSH diagnostic criteria was 43.80% for total subjects and 27.91% for shoulders, 12.79% for neck, and 11.24% for back/waist, respectively. 2) Factors affecting the prevalence of musculoskeletal symptoms were examined and multivariate logistic regression analysis was performed. As a result, women, having a burden of musculoskeletal work, increased work time in case of a higher risk of the prevalence of musculoskeletal symptoms (P<0.1). 3) The body parts and the department with the prevalence of musculoskeletal symptoms showed a significant difference (P<0.05) compared with symptoms on shoulders, arms/elbows, and ankles/feet. Conclusion: The prevalence of musculoskeletal symptoms by NIOSH diagnostic criteria in hotel employees was relatively high showing 43.80% for total subjects and higher in departments of laundry, reservations, cooking, food&beverage, dishwashing, and room cleaning than others.

• 한국의류산업학회지
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• 제21권6호
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• pp.800-812
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• 2019

Secondary diseases that occur during the rehabilitation of breast cancer survivors are factors that can negatively change the physical and psychological state of the patient. The rehabilitation after treatment of breast cancer survivors is an important process to prevent cancer recurrence and increase the survival rate because a negative psychological state significantly impacts the long-term survival rate. This study identifies user requirements for the development of functional bras for mastectomy patients in Korea. Participants included 133 patients with one or more breasts removed due to breast cancer and an average age of 53.2 years (53.21 ± 7.57 years, minimum 33 years, maximum 69 years). Women in their 50s had the highest participation rate of 48.9%. Most maintained the same bra size before surgery; however, some experienced changes in bra size because they are not irritated by wounds caused by surgery. Therefore, it is important to pay attention to material when designing a functional bra because it can irritate the surgical site. Only about 41.4% of bras were worn by breast cancer patients because of price burden and lack of education, not complaints related to clothing design and wearability or body shape. Most purchases at hospitals or medical institutions require consultation with a specialist who provides information about a bra mainly at the hospital. The most important considerations when buying a breast cancer bra were size, fit and shape stability.

• 한국환경보건학회지
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• 제27권3호
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• pp.1-10
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• 2001

This study was performed to evaluate chromium in air and chromium concentrations in whole blood and urine of workers at chrome plating factories, and to determine the correlation between environmental and biological chromium levels. This study involved 29 workers as study group and 24 undergraduate students as control group. The geometric means(GM) of airborne hexavalent chromium and total chromium concentrations in the plating factories were 3.4 $\mu\textrm{g}$/㎥ and 10.8 $\mu\textrm{g}$/㎥, respectively. Hexavalent chromium levels in two of total 29 measurements exceeded the korean occupational exposure limit and the American Conference of Governmental Industrial Hygienists Threshold Limit Value(ACGIH-TLV) of 50$\mu\textrm{g}$/㎥. Only one sample for total chromium exceeded the Korea occupational exposure limits, the ACGIH-TLV, and the National Institute for Occupational Safety and Health Recommended Exposure Limits(NIOSH-REL) of 500 $\mu\textrm{g}$/㎥. The GM of chromium concentrations in blood and urine of workers exposed to chromium were 8.4 $\mu\textrm{g}$/L and 11.9 $\mu\textrm{g}$/L. The GM of chromium concentrations in blood and urine of workers exposed to chromium were 8.4 $\mu\textrm{g}$/L and 11.9 $\mu\textrm{g}$/L, respectively, whereas the chromium concentrations in blood and urine of the controls were 1.6 $\mu\textrm{g}$/L and 3.8 $\mu\textrm{g}$/L, respectively. There were statistically significant differences of blood and urine concentrations between study group and control group (p<0.01). The chromium concentrations in urine were most highly related to hexavalent chromium, concentration in air(r=0.642, p<0.01). Also, there was a relatively high correlation between the hexavalent chromium concentrations in air and chromium concentrations in whole blood(r=0.557, p<0.05). These results indicate that whole-blood chromium with urinary chromium could be an indicator of chromium body burden caused by exposure to chromic acid mist in plating operation.

• Parasites, Hosts and Diseases
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• 제23권1호
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• pp.72-78
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• 1985

A total of 220 tadpoles was captured in 6 areas and total 117 frogs, Rana nigromacuzata, were collected in 11 areas in Korea. They were examined for their infection status by the metacercariae of Fibricola seoulensis by peptic digestion technique and by histological observation with hematoBylineosin staining. This study was carried out from August, 1983 to September, 1984. Followings are the results. 1. The tadpoles of R. nigromaculata were positive for the metacercariae from 3.3% to 100% by area. The number of metacercariae per infected tadpole ranged from 1 to 584, and the mean number Per tadpole ranged from 7.6 to 221 by area. 2. The metacercariae from 16 tadpoles were counted by the body portion. A great majority of the metacercariae was collected from abdominal cavity, 98.3% of 484 counted larvae. And 6(1.2%) larvae were from proximal tail and 2(0.4%) from trunk. 3. Histological sections of tadpoles showed many metacercariae in abdominal cavity but none in other parts. The larvae were free in the spaces among intestinal loops or around primitive liver. A few larvae were in duct-like tissues near trunk wall. There was little infiltration of inaammatory cells. 4. The metacercarial infection rates of frogs ranged from 0% to 100% by area. The larval burden was 1 to 470 by infected frogs, and mean number ranged from 1 to 175.6 by area. By above results, it is suggested that the cercariae of F. seoulensis may infect R. nigromaculata already in the stage of tadpole. Almost all of the metacercariae were concentrated in abdominal cavity of tadpoles. According to the infection status of frogs, this nuke is prevalent almost nationwidely in rice paddies in Korea.

• Journal of Microbiology and Biotechnology
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• 제30권8호
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• pp.1132-1141
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• 2020

Inflammatory bowel disease (IBD) is an increasing global burden and a predisposing factor to colorectal cancer. Although a number of treatment options are available, the side effects could be considerable. Studies on fecal microbiota transplantation (FMT) as an IBD intervention protocol require further validation as the underlying mechanisms for its attenuating effects remain unclear. This study aims to demonstrate the ameliorative role of FMT in an ulcerative colitis (UC) model induced by dextran sulfate sodium (DSS) and elucidate its relative mechanisms in a mouse model. It was shown that FMT intervention decreased disease activity index (DAI) levels and increased the body weight, colon weight and colon length of experimental animals. It also alleviated histopathological changes, reduced key cytokine expression and oxidative status in the colon. A down-regulated expression level of genes associated with NF-κB signaling pathway was also observed. The results of 16S rRNA gene sequencing showed that FMT intervention restored the gut microbiota to the pattern of the control group by increasing the relative abundance of Firmicutes and decreasing the abundances of Bacteroidetes and Proteobacteria. The relative abundances of the genera Lactobacillus, Butyricicoccus, Lachnoclostridium, Olsenella and Odoribacter were upregulated but Helicobacter, Bacteroides and Clostridium were reduced after FMT administration. Furthermore, FMT administration elevated the concentrations of SCFAs in the colon. In conclusion, FMT intervention could be suitable for UC control, but further validations via clinical trials are recommended.