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Effect of Lythrum salicaria Extract on Body Fat Reduction: A Protocol for a Randomized, Double-Blinded, Placebo-Controlled Clinical Trial (체지방 감소에 대한 털부처꽃 추출물의 효과: 무작위배정, 이중눈가림, 대조군 비교 인체적용시험 프로토콜)

  • Hye-Jin Park;In Heo;Yea-Jin Park;Hyo-Jin An;Su Shin;Yun-Yeop Cha
    • Journal of Korean Medicine for Obesity Research
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    • v.24 no.1
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    • pp.87-93
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    • 2024
  • Objectives: Obesity is a globally prevalent public health issue. Hence, there is a need for the development of safer and more effective anti-obesity drugs. Lythrum salicaria, a traditional medicinal herb used for centuries, has been reported to improve lipid metabolism and fat accumulation. It also has a low toxicity profile. Therefore, its potential as a functional ingredient in health functional foods needs to be evaluated. Methods: In this randomized, double-blind, placebo-controlled clinical trial, 90 participants will be randomly assigned to either the experimental or control group. Each subject will orally receive L. salicaria extract (1,350 mg/day) (500 mg L. salicaria+850 mg lactose as vehicle) or lactose (1,350 mg/day) as a hard capsule formula for 84 days (12 weeks). The primary outcome will be body fat mass (kg), which will be assessed using dual-energy x-ray absorptiometry (DXA) (performed only at visits 2 and 4). Secondary outcomes include body mass index, body weight, waist-to-hip ratio, body fat percentage (%) measured using DXA, lean body mass (kg) measured using DXA (assessed only at visits 2 and 4), lipids (total cholesterol, triglyceride, high-density lipoprotein cholesterol, and calculated low-density lipoprotein cholesterol), free fatty acid, high sensitivity C-reactive protein, adiponectin, and leptin. Conclusions: This protocol will be implemented after approval of Institutional Review Board of Pusan National University Korean Medicine Hospital (approval number: PNUKHIRB-2022-08-002) and registration with the Korean National Clinical Research Information Service (CRIS) (CRIS-KCT0008060). The results of this trial will provide potential of L. salicaria as a new anti-obesity functional food with fat-reducing effects and low toxicity.

Estimation of Maximum Outward Heel Angle During Turning of Pure Car and Truck Carriers (자동차운반선 선회 중 최대 횡경사각 추정에 관한 연구)

  • Hyeok-beom Ju;Deug-bong Kim
    • Journal of the Korean Society of Marine Environment & Safety
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    • v.30 no.4
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    • pp.324-331
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    • 2024
  • The height of large car and truck carriers from the keel to the wheel house is 44 ~ 46 m, and as the car-carriers increases in size, it exhibits the 'top heavy' characteristic, where the upper section is heavier than the lower section. This study aims to estimate the maximum outward heel angle of the Golden Ray car-carrier (G-ship) during turning maneuvers for accident investigation and the prevention of similar accidents. The theoretically calculated maximum outward heel is 7.5° (at 19 kn, rudder angle 35°) with a GM of +3.0 m or higher, and 16.7° with a GM of +1.85 m. Meanwhile the experimentally modified maximum outward heel is 10.5° (at 19 kn, rudder angle 35°) with a GM of +3.0 m or higher, and 23.3° with a GM of +1.85 m. The G-ship is maneuvered during an accident at a speed of 13 kn, at starboard rudder angle of 10° to 20°, it changes course from 038°(T) to 105°(T) based on the instructions of the on-board pilot. At this time, the maximum outward heel is estimated to be between 7.8° and 10.9° at the port side, which is 2.2 times higher than the normal outward heel. In the IS code, cargo ships are required to exhibit a minimum GoM of +0.15 m or more. The maneuvered G-ship exhibits a GoM of +1.72 m. It is not maneuvered because it fails to satisfy the international GoM criteria and because its GoM is insufficient to counteract the heeling moment during the maneuver. This study is performed based on accident-investigation results from the Korea Maritime Safety Tribunal and the USCG.

Analysis of Domestic and Overseas Radioactive Waste Maritime Transportation and Dose Assessment for the Public by Sinking Accident (국내·외 방사성폐기물 해상운반 현황 및 침몰사고 시 일반인 선량평가 사례 분석)

  • Ga Eun Oh;Min Woo Kwak;Hyeok Jae Kim;Kwang Pyo Kim
    • Journal of Radiation Industry
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    • v.18 no.1
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    • pp.35-42
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    • 2024
  • Demand for RW transportation is expected to increase due to the continuous generation of RW from nuclear power plants and facilities, decommissioning of plants, and saturation of spent fuel temporary storage facilities. The locational aspect of plants and radiation protection optimization for the public have led to an increasing demand for maritime transportation, necessitating to apprehend the overseas and domestic current status. Given the potential long-term radiological impact on the public in the event of a sinking accident, a pre-transportation exposure assessment is necessary. The objective of this study is to investigate the overseas and domestic RW maritime transportation current status and overseas dose assessment cases for the public in sinking accident. Selected countries, including Japan, UK, Sweden, and Korea, were examined for transport cases, Japan and the U.S were chosen for dose assessment case in sinking accidents. As a result of the maritime transportation case analysis, it was performed between nuclear power plants and reprocessing facilities, from plants to disposal or intermediate storage facilities. HLW and MOX fuel were transported using INF 3 shipments, and all transports were performed low speed of 13 kn or less. As a result of the dose assessment for the public in sinking accident, japan conducted an assessment for the sinking of spent fuel and vitrified HLW, and the U.S conducted for the sinking of spent fuel. Both countries considered external exposure through swimming and working at seashore, and internal exposure through seafood ingestion as exposure pathway. Additionally, Japan considered external exposure through working on board and fishing, and the U.S considered internal exposure through spray inhalation and desalinized water and salt ingestion. Internal exposure through seafood ingestion had the largest dose contribution. The average public exposure dose was 20 years after the sinking, 0.04 mSv yr-1 for spent fuel and 5 years after the sinking, 0.03 mSv yr-1 for vitrified HLW in Japan. In the U.S, it was 1.81 mSv yr-1 5 years after the sinking of spent fuel. The results of this study will be used as fundamental data for maritime transportation of domestic RW in the future.

2023 Survey on User Experience of Artificial Intelligence Software in Radiology by the Korean Society of Radiology

  • Eui Jin Hwang;Ji Eun Park;Kyoung Doo Song;Dong Hyun Yang;Kyung Won Kim;June-Goo Lee;Jung Hyun Yoon;Kyunghwa Han;Dong Hyun Kim;Hwiyoung Kim;Chang Min Park;Radiology Imaging Network of Korea for Clinical Research (RINK-CR)
    • Korean Journal of Radiology
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    • v.25 no.7
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    • pp.613-622
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    • 2024
  • Objective: In Korea, radiology has been positioned towards the early adoption of artificial intelligence-based software as medical devices (AI-SaMDs); however, little is known about the current usage, implementation, and future needs of AI-SaMDs. We surveyed the current trends and expectations for AI-SaMDs among members of the Korean Society of Radiology (KSR). Materials and Methods: An anonymous and voluntary online survey was open to all KSR members between April 17 and May 15, 2023. The survey was focused on the experiences of using AI-SaMDs, patterns of usage, levels of satisfaction, and expectations regarding the use of AI-SaMDs, including the roles of the industry, government, and KSR regarding the clinical use of AI-SaMDs. Results: Among the 370 respondents (response rate: 7.7% [370/4792]; 340 board-certified radiologists; 210 from academic institutions), 60.3% (223/370) had experience using AI-SaMDs. The two most common use-case of AI-SaMDs among the respondents were lesion detection (82.1%, 183/223), lesion diagnosis/classification (55.2%, 123/223), with the target imaging modalities being plain radiography (62.3%, 139/223), CT (42.6%, 95/223), mammography (29.1%, 65/223), and MRI (28.7%, 64/223). Most users were satisfied with AI-SaMDs (67.6% [115/170, for improvement of patient management] to 85.1% [189/222, for performance]). Regarding the expansion of clinical applications, most respondents expressed a preference for AI-SaMDs to assist in detection/diagnosis (77.0%, 285/370) and to perform automated measurement/quantification (63.5%, 235/370). Most respondents indicated that future development of AI-SaMDs should focus on improving practice efficiency (81.9%, 303/370) and quality (71.4%, 264/370). Overall, 91.9% of the respondents (340/370) agreed that there is a need for education or guidelines driven by the KSR regarding the use of AI-SaMDs. Conclusion: The penetration rate of AI-SaMDs in clinical practice and the corresponding satisfaction levels were high among members of the KSR. Most AI-SaMDs have been used for lesion detection, diagnosis, and classification. Most respondents requested KSR-driven education or guidelines on the use of AI-SaMDs.

Performance of ChatGPT 3.5 and 4 on U.S. dental examinations: the INBDE, ADAT, and DAT

  • Mahmood Dashti;Shohreh Ghasemi;Niloofar Ghadimi;Delband Hefzi;Azizeh Karimian;Niusha Zare;Amir Fahimipour;Zohaib Khurshid;Maryam Mohammadalizadeh Chafjiri;Sahar Ghaedsharaf
    • Imaging Science in Dentistry
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    • v.54 no.3
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    • pp.271-275
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    • 2024
  • Purpose: Recent advancements in artificial intelligence (AI), particularly tools such as ChatGPT developed by OpenAI, a U.S.-based AI research organization, have transformed the healthcare and education sectors. This study investigated the effectiveness of ChatGPT in answering dentistry exam questions, demonstrating its potential to enhance professional practice and patient care. Materials and Methods: This study assessed the performance of ChatGPT 3.5 and 4 on U.S. dental exams - specifically, the Integrated National Board Dental Examination (INBDE), Dental Admission Test (DAT), and Advanced Dental Admission Test (ADAT) - excluding image-based questions. Using customized prompts, ChatGPT's answers were evaluated against official answer sheets. Results: ChatGPT 3.5 and 4 were tested with 253 questions from the INBDE, ADAT, and DAT exams. For the INBDE, both versions achieved 80% accuracy in knowledge-based questions and 66-69% in case history questions. In ADAT, they scored 66-83% in knowledge-based and 76% in case history questions. ChatGPT 4 excelled on the DAT, with 94% accuracy in knowledge-based questions, 57% in mathematical analysis items, and 100% in comprehension questions, surpassing ChatGPT 3.5's rates of 83%, 31%, and 82%, respectively. The difference was significant for knowledge-based questions(P=0.009). Both versions showed similar patterns in incorrect responses. Conclusion: Both ChatGPT 3.5 and 4 effectively handled knowledge-based, case history, and comprehension questions, with ChatGPT 4 being more reliable and surpassing the performance of 3.5. ChatGPT 4's perfect score in comprehension questions underscores its trainability in specific subjects. However, both versions exhibited weaker performance in mathematical analysis, suggesting this as an area for improvement.

A Study on The Awareness And Practice Of Hand Washing According Medical care onboard Of Seafarers (선원의 의료관리자 자격 유무에 따른 손 씻기의 인식도와 실천도)

  • Sung-Lyoung Kim;Yu-Jin Park
    • The Journal of the Convergence on Culture Technology
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    • v.10 no.5
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    • pp.505-511
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    • 2024
  • This study is to identify the awareness and performance of hand washing according to the presence of Medical care onboard of Seafarers and provide basic data of education on hand washing that can be practically applied. 118 Seafarers were the study subjects and we distributed to those who agreed to participate in the study to carry out survey using questionnaire. The results showed that the average number of hand washing per day was 1~4 times (70 students, 59.3%). In the difference in hand washing perception according to the medical care board, statistically significant differences were found in all items except 'it needs to be completely dried after hand washing'(p<0.05). The difference in hand washing performance according to in-flight medical care was found to be statistically significant in all items except 'hand washing after coughing' and 'hand washing after touching money', 'before eating food such as drinks while working' and 'hand washing before patient contact' (p<0.05). The correlation between awareness and performance of hand washing showed that if awareness of hand washing is high, its performance is increased, too. We try to provide basic data of education on hand washing that can improve awareness and performance on hand washing based on the results of this study.

Implementation of a real-time public transportation monitoring system (실시간 대중교통 모니터링 시스템 구현)

  • Eun-seo Oh;So-ryeong Gwon;Joung-min Oh;Bo Peng;Tae-kook Kim
    • Journal of Internet of Things and Convergence
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    • v.10 no.4
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    • pp.9-19
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    • 2024
  • In this paper, a real-time public transportation monitoring system is proposed. The proposed system was implemented by developing a public transportation app and utilizing optical sensors, pressure sensors, and an object detection algorithm. Additionally, a bus model was created to verify the system's functionality. The proposed real-time public transportation monitoring system has three key features. First, the app can monitor congestion levels within public transportation by detecting seat occupancy and the total number of passengers based on changes in optical and pressure sensor readings. Second, to prevent errors in the optical sensor that can occur when multiple passengers board or disembark simultaneously, we explored the possibility of using the YOLO object detection algorithm to verify the number of passengers through CCTV footage. Third, convenience is enhanced by displaying occupied seats in different colors on a separate screen. The system also allows users to check their current location, available public transportation options, and remaining time until arrival. Therefore, the proposed system is expected to offer greater convenience to public transportation users.

Development of a Multi-Camera Inline System using Machine Vision System for Quality Inspection of Pharmaceutical Containers (의약 용기의 품질 검사를 위한 머신비전을 적용한 다중 카메라 인라인 검사 시스템 개발)

  • Tae-Yoon Lee;Seok-Moon Yoon;Seung-Ho Lee
    • Journal of IKEEE
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    • v.28 no.3
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    • pp.469-473
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    • 2024
  • In this paper proposes a study on the development of a multi-camera inline inspection system using machine vision for quality inspection of pharmaceutical containers. The proposed technique captures the pharmaceutical containers from multiple angles using several cameras, allowing for more accurate quality assessment. Based on the captured data, the system inspects the dimensions and defects of the containers and, upon detecting defects, notifies the user and automatically removes the defective containers, thereby enhancing inspection efficiency. The development of the multi-camera inline inspection system using machine vision is divided into four stages. First, the design and production of a control unit that fixes or rotates the containers via suction. Second, the design and production of the main system body that moves, captures, and ejects defective products. Third, the design and development of control logic for the embedded board that controls the entire system. Finally, the design and development of a user interface (GUI) that detects defects in the pharmaceutical containers using image processing of the captured images. The system's performance was evaluated through experiments conducted by a certified testing agency. The results showed that the dimensional measurement error range of the pharmaceutical containers was between -0.30 to 0.28 mm (outer diameter) and -0.11 to 0.57 mm (overall length), which is superior to the global standard of 1 mm. The system's operational stability was measured at 100%, demonstrating its reliability. Therefore, the efficacy of the proposed multi-camera inline inspection system using machine vision for the quality inspection of pharmaceutical containers has been validated.

Perception of School Foodservice Officials on Rice Bread as School Foodservice Menu (쌀빵에 대한 인식 및 학교급식 적용 가능성 분석: 교육청 학교급식 담당자를 중심으로)

  • Yang, Il-Sun;Lee, Min-A;Cha, Sung-Mi;Jo, Yoon-Hee;Lee, So-Young;Lee, So-Jung;Lee, Hae-Young
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.37 no.6
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    • pp.729-737
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    • 2008
  • The purposes of this study were to investigate supporting status and subsidy for school food service and to analyze the perception of school food service officials at the educational board on using rice bread to the school food service menu. The questionnaire was developed by content analysis, situation analysis, in-depth interview and checked by the school food service officials at the educational board. The questionnaires were responded by 33 officials (respondent rate: 86.8%) during September 1 to October 26 in 2007. The major findings of this study were as follows: First, most of the respondents were women (93.9%), and worked an average of 104.36 months at school-related work. The metropolitan & provincial office of education had prevalently jurisdiction over 272.3 rural and self-operation type of elementary schools, 115.50 rural and self-operation type of middle schools and 73.0 rural and self-operation type of high schools. In the case of the district office of education, 23.3 urban and self-operation type of elementary schools, 11.6 urban and self-operation type of middle schools and 5.3 urban and contracted type of high schools were averagely managed. Second, all the respondents supported meal cost for low-income group and 50.5% provided reimbursement for organic environmental agricultural products. The highest subsidy was 16.8 billion won as meal cost for low-income group in metropolitan & provincial office and 1,050 million won as labor cost in district office. Third, the experience of performing policies for using rice was relatively lower than perception of rice bread application to school food service menu. Fourth, the advantages of using rice bread were acceleration of consuming rice (32.0%), excellence of nutrition (24.0%) and promotion of healthy image (22.7%). On the other hand, the difficulties of using rice bread were lack of facilities (72.7%), higher cost compared to wheat bread (54.5%), limitation of menu application and cooking method (15.7% each). Fifth, the opinion of utilizing rice and that of applying rice bread were significantly correlated (p<0.001). Desirability and willingness were correlated with reality for applying rice bread to the school food service menu (p<0.001). Also, comparative analysis between divided groups by perception of utilizing rice showed that willingness and experience were significantly different.

Indonesia, Malaysia Airline's aircraft accidents and the Indonesian, Korean, Chinese Aviation Law and the 1999 Montreal Convention

  • Kim, Doo-Hwan
    • The Korean Journal of Air & Space Law and Policy
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    • v.30 no.2
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    • pp.37-81
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    • 2015
  • AirAsia QZ8501 Jet departed from Juanda International Airport in, Surabaya, Indonesia at 05:35 on Dec. 28, 2014 and was scheduled to arrive at Changi International Airport in Singapore at 08:30 the same day. The aircraft, an Airbus A320-200 crashed into the Java Sea on Dec. 28, 2014 carrying 162 passengers and crew off the coast of Indonesia's second largest city Surabaya on its way to Singapore. Indonesia's AirAsia jet carrying 162 people lost contact with ground control on Dec. 28, 2014. The aircraft's debris was found about 66 miles from the plane's last detected position. The 155 passengers and seven crew members aboard Flight QZ 8501, which vanished from radar 42 minutes after having departed Indonesia's second largest city of Surabaya bound for Singapore early Dec. 28, 2014. AirAsia QZ8501 had on board 137 adult passengers, 17 children and one infant, along with two pilots and five crew members in the aircraft, a majority of them Indonesian nationals. On board Flight QZ8501 were 155 Indonesian, three South Koreans, and one person each from Singapore, Malaysia and the UK. The Malaysia Airlines Flight 370 departed from Kuala Lumpur International Airport on March 8, 2014 at 00:41 local time and was scheduled to land at Beijing's Capital International Airport at 06:30 local time. Malaysia Airlines also marketed as China Southern Airlines Flight 748 (CZ748) through a code-share agreement, was a scheduled international passenger flight that disappeared on 8 March 2014 en route from Kuala Lumpur International Airport to Beijing's Capital International Airport (a distance of 2,743 miles: 4,414 km). The aircraft, a Boeing 777-200ER, last made contact with air traffic control less than an hour after takeoff. Operated by Malaysia Airlines (MAS), the aircraft carried 12 crew members and 227 passengers from 15 nations. There were 227 passengers, including 153 Chinese and 38 Malaysians, according to records. Nearly two-thirds of the passengers on Flight 370 were from China. On April 5, 2014 what could be the wreckage of the ill-fated Malaysia Airlines was found. What appeared to be the remnants of flight MH370 have been spotted drifting in a remote section of the Indian Ocean. Compensation for loss of life is vastly different between US. passengers and non-U.S. passengers. "If the claim is brought in the US. court, it's of significantly more value than if it's brought into any other court." Some victims and survivors of the Indonesian and Malaysia airline's air crash case would like to sue the lawsuit to the United States court in order to receive a larger compensation package for damage caused by an accident that occurred in the sea of Java sea and the Indian ocean and rather than taking it to the Indonesian or Malaysian court. Though each victim and survivor of the Indonesian and Malaysia airline's air crash case will receive an unconditional 113,100 Unit of Account (SDR) as an amount of compensation for damage from Indonesia's AirAsia and Malaysia Airlines in accordance with Article 21, 1 (absolute, strict, no-fault liability system) of the 1999 Montreal Convention. But if Indonesia AirAsia airlines and Malaysia Airlines cannot prove as to the following two points without fault based on Article 21, 2 (presumed faulty system) of the 1999 Montreal Convention, AirAsia of Indonesiaand Malaysia Airlines will be burdened the unlimited liability to the each victim and survivor of the Indonesian and Malaysia airline's air crash case such as (1) such damage was not due to the negligence or other wrongful act or omission of the air carrier or its servants or agents, or (2) such damage was solely due to the negligence or other wrongful act or omission of a third party. In this researcher's view for the aforementioned reasons, and under the laws of China, Indonesia, Malaysia and Korea the Chinese, Indonesian, Malaysia and Korean, some victims and survivors of the crash of the two flights are entitled to receive possibly from more than 113,100 SDR to 5 million US$ from the two airlines or from the Aviation Insurance Company based on decision of the American court. It could also be argued that it is reasonable and necessary to revise the clause referring to bodily injury to a clause mentioning personal injury based on Article 17 of the 1999 Montreal Convention so as to be included the mental injury and condolence in the near future.