• 제목/요약/키워드: blood. diabetes.

검색결과 1,691건 처리시간 0.027초

한국 성인 2형 당뇨병 환자를 위한 당뇨 중재 프로그램 효과에 대한 메타 분석 (Meta-Analysis of the Effect of Diabetes Intervention Programs for Korean Adults with Type 2 Diabetes)

  • 박미영;김정민
    • 한국식품영양학회지
    • /
    • 제35권3호
    • /
    • pp.193-203
    • /
    • 2022
  • This study aimed to provide directions and implications for a future program by analyzing studies on diabetes programs from 2000 to 2020. Among the studies with control and experimental groups, the selected studies included ones that provided intervention to patients with diabetes and ones that contained descriptive statistics. Sixteen studies were selected to verify the effectiveness and homogeneity of the data coding meta-analysis. The overall effect size in the diabetes program combined estimate was 0.398 (95% CI: 0.268, 0.425, p=0.000). Among the dependent variables, fasting blood glucose (-0.616) and glycated hemoglobin (-0.442) showed median effect sizes, but the effect of fasting blood glucose was not statistically significant. In terms of the study design, non-randomized control trials (NRCTs) (-0.543) was more effective than randomized control trials (RCTs) (0.719). Among, the counseling and self-management program (-3.241) showed a very large effect size. Furthermore, the cognitive-behavioral (-0.828) and self-management (-0.482) programs were also found to have a positive effect on lowering fasting blood glucose. As the importance of diabetes management increases, further studies based on RCT should be actively performed, and differentiated and specialized diabetes intervention plans need to be established.

Effects of obesity adult participation in boxing diets on weight loss, blood pressure and blood sugar improvements

  • Park, Noh-hwan;Kim, Kwan-kyu
    • International Journal of Advanced Culture Technology
    • /
    • 제6권4호
    • /
    • pp.205-213
    • /
    • 2018
  • This research is about effects of obesity adults participating in 12weeks of boxing diets program on weight loss, blood pressure and blood sugar improvements. The exercise program was conducted three times a week with a maximum heart rate of 50 to 65 percent for first to forth weeks and 65 to 85 percent for fifth to twelfth. The study included 59 obese people in their 20s and 50s, with a BMI of 25kg/m2 or higher, blood pressure of 140/90mmHg, and high blood pressure and diabetes patients of 125 mg/dl per fasting blood sugar. The following results were obtained by observing the results before and after the boxing exercise program. High blood pressure, diabetes, high blood pressure + diabetes after 12 weeks showed significant weight, BMI and body fat reduction, as well as significant decrease in blood pressure and fasting blood sugar. Consequently, through this study, obese adults can lower their weight, blood pressure, and blasting fasting blood sugar through a 12-week high-strength boxing exercise program and it is believed to help improve and prevent obesity, cardiovascular disease and metabolic diseases.

Alloxan 당뇨병에 대한 인삼의 효과 (The Effect of Korean Ginseng on Alloxan Diabetes)

  • 홍성표;임무현;주현규
    • 생약학회지
    • /
    • 제7권2호
    • /
    • pp.111-114
    • /
    • 1976
  • This study was aimed to investigate the effects of Ginseng ethanol extract on Diabetes induced by alloxan in comparison with that of insulin. The blood sugar, blood urea nitrogen, glutamic oxaloacetic transaminase and cholesterol were measured by spectrophotometry. The results were obtained as follows. 1. Ethanol extract of Ginseng increased the blood sugar level in normal rats. 2. Ethanol extract of Ginseng restrained the increase of blood sugar in diabetes induced by alloxan. 3. Ethanol extract of Ginseng acted to oppose a rapid decrease of blood sugar by insulin. 4. Blood urea nitrogen, glutamic oxaloacetic transaminase and cholesterol level in blood were not affected by Ginseng.

  • PDF

Oral administration of Grifola frondosa affect lipid metabolism and insulin signaling pathway on BKS. Cg-+Leprdb/+Leprdb/OlaHsd mouse

  • Yun, Seong-Bo;Kim, Dae-Young
    • 한국동물생명공학회지
    • /
    • 제36권4호
    • /
    • pp.203-211
    • /
    • 2021
  • Diabetic mellitus (DM) is a carbohydrate metabolic disorder that involves high blood sugar because insulin works abnormally. Type 2 diabetes accounts for most of them. However, diabetes treatments such as GLP-1 and DPP-4 inhibitors commonly caused side effects including gastrointestinal disorders. Grifola frondosa (G. frondosa) revealed various pharmacological effects in recent studies. It has a variety of anti-cancer polysaccharides through host-mediated mechanisms. D-fraction in G. frondosa has apoptotic effects, promoting myeloid cell proliferation and differentiation into granulocytes-macrophages. It has also been shown to reduce the survival rate of breast cancer cells. Though, no further study has been conducted on the specific effects of G. frondosa in the db/db mouse. Therefore, we would like to research the blood glucose improving effect of G. frondosa, a natural material, in type 2 diabetes model mouse, in this study. G. frondosa was administered to the disease model mouse (BKS.Cg-+Leprdb/+Leprdb/OlaHsd) for 8 weeks to monitor weight and blood glucose changes every week. And we evaluated anti-diabetes effects by checking biomarker changes shown through blood. Experiment did not show statistically significant weight differences, but control groups showed significantly higher weight gain than G. frondosa administered groups. We collected blood from the tail veins of the db/db mouse each week. As a result, the lowest blood sugar level was shown in the 500 mg/kg group of G. frondosa. Glucose in the blood was examined with HBA1c, and 7.8% was shown in the 500 mg/kg administration group, lower than in other groups. These results suggest the potential improvements of diabetes in G. frondosa.

비타민 C 보충이 제 2형 당뇨병 환자의 혈당 및 항산화상태에 미치는 효과 (Effect of Vitamin C Supplementation on Blood Sugar and Antioxidative Status in Types II Diabetes Mellitus Patients)

  • 박형숙;이윤미
    • 대한간호학회지
    • /
    • 제33권2호
    • /
    • pp.170-178
    • /
    • 2003
  • Purpose: This study was to determine the effect of oral vitamin C supplements on blood sugar and antioxidative status in Types II diabetes mellitus patients. Method: Data for the study were collected from June 24 to August 31, 2001. Participants(31) took 1g/day vitamin C for 4 weeks, after a 1 - week taking no Vitamin C, followed by Vitamin C 3g/day for 4 weeks. A baseline blood sample was obtained following a 12hour overnight fast and at the end of each 4week Vitamin C administration. Blood samples were taken for plasma vitamin C concentration, fasting blood sugar, HbA1c, superoxide scavenging activity and hydrogen peroxide scavenging activity. The data were analyzed by SPSS for repeated measures ANOVA. Result: Plasma vitamin C concentration was significantly increased over dose(F=3.316, p=.043). Fasting blood sugar and HbA1c was significantly decreased over dose(F=13.192, p=.000; F=11.995, p=.000). Superoxide scavenging activity and hydrogen peroxide scavenging activity was significantly increased over dose(F=486.138, p=.000; F=177.704, p= .000). Conclusion: The results suggest that megadose vitamin C supplementation may have a beneficial effect in diabetes mellitus patients on both glycemic control and antioxidant status. Thus dietary measures to increase plasma vitamin C may be an important health strategy for reducing the compliance of diabetic patients

혈당 조절 양호, 불충분, 불량 군 간의 자가간호행위, 당뇨관련 스트레스, 스트레스 대처의 비교 (Comparative Study on Self-Care Behavior, Diabetes-related Stress, and Stress Coping among Good, Inadequate, and Poor Glycemic Control Groups)

  • 강혜연;구미옥
    • 기본간호학회지
    • /
    • 제19권2호
    • /
    • pp.168-178
    • /
    • 2012
  • Purpose: The purpose of this study was to compare self-care behavior, diabetes-related stress and stress coping style among 3 blood glucose control groups (good, inadequate, and poor blood glucose control groups). Methods: Participants were 102 type 2 diabetic patients (good group: 41, inadequate group: 31, poor group: 30). Data were collected from Feb 19 to Mar 24, 2010 and were analyzed using Chi-square, Fisher's exact test and ANCOVA with SPSS/WIN 12.0. Results: Using ANCOVA with frequency of admission, and illness duration as covariates, significant differences were found among the 3 groups in self-care behavior (total score) and the exercise subscale. Using ANCOVA significant differences were found among 3 groups in diabetes-related stress (total score), emotional burden subscale and regimen distress subscale. Using ANCOVA no difference in stress coping was found among the 3 groups, but there was a significant difference in the problem-oriented coping subscale. Conclusions: Self-care behavior, diabetes-related stress, and stress coping style are factors influencing blood glucose control. The results of this study suggest that for improving blood glucose control, self care education program focused on diet and exercise in addition to stress management program for promoting problem oriented coping capability are recommended.

딥러닝 이미지 분석을 통한 당뇨병 환자 식이요법 서포팅 서비스 개발 (Developing Diet Supporting Service for Diabetes Patients through Deep Learning Image Analysis)

  • 서시현;양희범;김기융;박현준
    • 한국정보통신학회:학술대회논문집
    • /
    • 한국정보통신학회 2022년도 추계학술대회
    • /
    • pp.62-65
    • /
    • 2022
  • 당뇨병은 전 세계적으로도 발병률 및 유병률이 매년 증가하는 사회적 중대한 문제이다. 혈중 포도당의 농도가 높아지는 고혈당을 특징으로 한 당뇨병은 여러 증상 및 징후를 일으키고 있다. 그로 인해 환자들이 일상생활에서의 자가관리 강화를 인지하고 실천해야 한다. 하지만 환자들이 자가관리에 있어서 실패하는 가장 큰 요인을 식이요법 실패로 꼽고 있다. 이에 본 논문에서는 사진 촬영 또는 이미지 업로드를 통해 식단을 입력하고 섭취지표와 혈당 통계를 통해 사용자들의 식단을 분석해주는 애플리케이션을 설계 및 구현하였다.

  • PDF

비만 제2형 당뇨병 환자에서 중성지방과 C-peptide 증가 (Triglycerides and C-peptide are Increased in Obese Type 2 Diabetic Patients)

  • 김희승;송민선;유양숙
    • Journal of Korean Biological Nursing Science
    • /
    • 제4권2호
    • /
    • pp.41-49
    • /
    • 2002
  • Aim To evaluate blood pressure, blood glucose and serum lipid level in obese and nonobese type 2 diabetic patients. Methods 206 obese(76 male, 130 female) and 442 nonobese(208 male, 234 female) type 2 diabetic patients underwent fasting blood glucose, 2-hour postprandial blood glucose, $HbA_1c$ total cholesterol, triglyceride, high density lipoprotein, microalbuminuria, blood urea nitrogen, creatinine and C-peptide were measured. Diabetes was diagnosed according to the American Diabetes Association(ADA)criteria. Obesity was defined as body mass index(BMI, kilograms per meters squared)${\geq}25$. Results In male, systolic blood pressure, triglycerides, microalbuminuria and C-peptide were significant higher in obese than nonobese patients. Fasting blood glucose were significantly lower in obese than nonobese patients. Diastolic blood pressure, 2-hour postprandial blood glucose, $HbA_1c$, total cholesterol, high density lipoprotein, blood urea nitrogen, and creatinine were no difference between 2 groups. In female, triglycerides and C-peptide were significant higher in obese than nonobese patients, Blood pressure, fasting blood glucose, 2-hour postprandial blood glucose, $HbA_1c$, total cholesterol, high density lipoprotein, microalbuminuria, blood urea nitrogen, and creatinine were no difference between 2 groups. Conclusion Our present study supports that increased triglycerides play a major role in increasing the risk of coronary heart disease(CHD) in obese women type 2 diabetic patients.

  • PDF

고려인삼과 당뇨병: 세포와 동물 및 인체실험을 통한 고려인삼의 당뇨병에 대한 효능 (Korean Ginseng and Diabetes: An Insight into Antidiabetic Effects of Korean Ginseng (Panax ginseng C. A. Meyer) in Cultured Cells, Animal Models and Human Studies)

  • 서성호;박건국;박종대
    • 생약학회지
    • /
    • 제51권1호
    • /
    • pp.1-29
    • /
    • 2020
  • Diabetes mellitus, commonly known as diabetes, is a group of metabolic disorders characterized by high blood sugar levels over a prolonged period. Diabetes has been found to show many acute complications such as cardiovascular disease, stroke, chronic kidney disease, foot ulcer and damage to eyes. Korean ginseng (Panax ginseng) has been traditionally known to normalize the functional deficiencies of the lung, spleen and stomach, and thus improve the secretion of body fluids, thereby quenching thirst, suggesting it to be effective in the treatment of diabetes. Experimental studies (in vitro and in vivo) have recently shown that Korean ginseng and its extracts exhibit antidiabetic effects, and also insulin secretion and sensitizing effects related to blood glucose control. Moreover, clinical trials on antidiabetic effects of Korean ginseng have been reported to show blood glucose control, improvement of insulin resistance, reduction of postprandial blood glucose level and improvement of serum lipids (TG, TC, LDL-C). These will be critically examined by means of in vitro studies, cell experiment, animal models and human trials with a focus on understanding of molecular mechanisms.

Antidiabetic Effect of Beta vulgaris Mixture: Regulation of Glycolytic Enzymes and Pancreatic Beta Cells

  • Dae Sik Haam;Dong-Yeop Shin;Hak Yong Lee;Young Mi Park;Byeong-Soo Kim;Myung-Sunny Kim;Hye Jeong Yang;Na-Rae Shin
    • Journal of Food and Nutrition Research
    • /
    • 제10권1호
    • /
    • pp.32-40
    • /
    • 2022
  • Diabetes is a chronic metabolic disease with a high prevalence worldwide. Beet (Beta vulgaris) is a plant that is widely used in many countries and has various biological activities. In this study, we aimed to evaluate the antidiabetic effect of a B. vulgaris mixture (BM). In the in vitro evaluation, we measured the inhibitory activities of α-amylase and α-glucosidase, performed the oral starch tolerance test (OATT) and oral sucrose tolerance test (OSTT) in Sprague Dawley (SD) rats, and evaluated the clinical symptoms, oral glucose tolerance test (OGTT), number of blood cells, and insulin resistance in db/db mice. BM showed an inhibitory effect against α-amylase and α-glucosidase activity and decreased the blood glucose increased in the OATT and OSTT. In the diabetes mouse model, BM alleviated the general symptoms of diabetes and OGTT results showed a decrease in the increased blood sugar level. Regarding diabetes-related tissue weight, BM decreased the reduced pancreatic weight and showed an effect on diabetes-related factors of blood. Histological analysis indicated that BM decreased insulin concentration, insulin resistance, and insulin secretion ability in serum, and increased insulin concentration in the islets of Langerhans. These results demonstrate that BM has an antidiabetic effect through the regulation of glycolytic enzymes and β cell activity in the pancreas.