• 한국방사선학회논문지
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• 제3권4호
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• pp.5-12
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• 2009

총경동맥은 심장으로부터 혈액을 직접 대뇌로 전달하는 동맥 혈류 순환이 중요하며, 특히 동맥 혈관내의 혈액의 흐름을 방해하는 여러 변인들이 있다. 그 변인 중에서도 평균혈류속도, 맥박지수, 및 혈류 저항 변인 등이 있는데, 이중 맥박지수나 혈류저항지수는 최대 수축기와 이완기시 혈류속도와 관련이 되어있기 때문에 혈압과도 중요한 변인들이 된다, 이와 같은 뇌혈류 속도 변인들의 변화에 대해서 관찰하는 데는 비침습적인 초음파를 이용한 도플러 뇌혈류 측정법을 이용한다. 최대운동은 20대 남성에서 뇌로가는 혈류인 총경동맥의 혈류속도를 증가 시킬 수 있는 것으로 나타났다.

• 혜화의학회지
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• 제11권1호
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• pp.1-9
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• 2002

1. Purpose We inquire into difference of blood flow velocity according Sasang Constitution. 2. Method We selected observation group that they are 251 patients among of the patients who are had a medical early examination of stroke. We classified observation group by Sasang Constitution and compared each of measured blood flow velocity by TCD. 3. Result 1) We found out that Taeumin is highest in fat rate, height and blood pressure. 2) Blood flow mean velocity of MCA is not found out significant difference by Sasang Constitution. But, Taeumin is found out highest in left and right. 3) Taeumin is found out that blood flow velocity of Siphon sinus ICA is highest.

• 대한의용생체공학회:의공학회지
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• 제28권2호
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• pp.178-186
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• 2007

This study is attempted to correct an error of electronic blood pressure meter with an optical sensor. In general, for a hospitalized patient, ECG, blood pressure, oxygen saturation, and respiration are basically measured to monitor the patient's condition. Opening of a blood vessel after it is occluded by pressurizing the cuff influences the blood flow of peripheral blood vessels as well as oscillation changes in the cuff. Blood vessels are occluded and peripheral blood flow disappears at cuff pressure above the examinee's blood pressure, while blood vessels are opened and peripheral blood flow appears again at cuff pressure under the examinee's blood pressure. Then Disappear-Appear Point Length(DAPL) of peripheral blood flow can be judged with the signal of peripheral blood flow, thus is available as a factor of error correction for electronic blood pressure meter. Also, systolic or diastolic blood pressure can be corrected with Appear-Point-Pressure(APP) of cuff pressure at a point where blood flow occurs and Appear-Maximum Pressure(AMP) of cuff pressure at the maximum amplitude point of peripheral blood flow after peripheral blood flow appears again. For verification, 27 examinees were selected, and their blood value was obtained through experimental procedure of 4 stages including induction of blood pressure change. The examinees were divided into two groups of experimental group and control group, regression analysis was conducted for experimental group, and correction of a blood pressure error was verified with optical signal by applying the regression equation calculated in experimental group to control group. As an experimental result, mean of the whole measurement errors was 5mmHg or more, which did not meet the standard fur blood pressure meter. As a result of correcting blood pressure measurements with data of DAPL, APP, and AMP as drawn out of PPG signal, systolic blood pressure, mean blood pressure, and diastolic blood pressure were $-0.6{\pm}4.4mmHg,\;-1.0{\pm}3.9mmHg$ and $-1.3{\pm}5.4mmHg$, respectively, indicating that mean of the whole measurement errors was greatly improved, and standard deviation was decreased.

• International Journal of Vascular Biomedical Engineering
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• 제2권1호
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• pp.25-30
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• 2004

Catheters are used to measure translesional pressure gradients in the stenosed coronary arteries. Uses of catheters during coronary angioplasty cause flow obstructions. A narrowed flow cross section with catheter effectively introduced a tighter stenosis than the enlarged residual stenoses after balloon angiplasty. Catheters in blood vessels cause pressure gradient rise and blood flow drop during the measurements. In this study, three dimensional computer simulations are conducted to investigate the flow blockage effects due to the catheter obstructions during the coronary angioplasty. The computer simulation models are generated by the data, which are measured by coronary angiogram, and the blood is treated as non-Newtonian fluid. The velocity, pressure, and wall shear stress variations are observed for the estimate of damages of blood vessel. This study is also extended to investigate the effects of stenotic vessel size, and shape and catheter size and location.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2004년도 학술대회 논문집 정보 및 제어부문
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• pp.322-324
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• 2004

Up to the present, digital replantation patients has appealed different symptoms due to blood circulatory failure. But, the level of blood circulatory failure has been evaluated only by clinical symptoms, or angiography. According to the cases of digit replantation is increasing, then objective evaluation methods of the level of blood circulation failure is needed other than patient's subjective symptoms and complaints. Although angiography, doppler, electromagnetic flowmeter, laser blood flowmeter, mechanical blood flowmeter has been used for the evaluation of the blood circulatory failure, the result was affected by time, place, surrounding temperature, patient's body temperature, and even emotion. Therefore, it is pointed out with lack of availability, feasibility and reproducibility. Thus, we compared digital blood flow of dominant hand to non dominant hand, and replanted fingers to opposite normal fingers from developed photo-plethysmography. The average digital blood flow showed no difference in normal digits each other, but, replanted digits showed average of 53% (9 - 100 %) compare to opposit normal digits. As it measure relative blood flow for circulatory failure of tissue such as fingers and toes more sensitively, reliably. In conclusion, it is expected that photo- plethysmography will be very useful for diagnosis, curative effect, prognosis of blood circulatory failure in digital replantation patient.

• 한국의류산업학회지
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• 제21권4호
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• pp.459-467
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• 2019

Compression wear provides clothing pressure and affects how blood flows. Facilitating a blood flow is one of the most important functions of compression wear. The wearer's sensibility should be considered when designing compression wear. This study instructed participants to put on 5 types of sport compression wear with different pressure levels (CP-1 to CP-5), measured clothing pressure, blood flow level, blood flow rate, and surface temperature, and examined the pressure level that influenced blood flow through a subjective sensibility assessment. An experiment measured the clothing pressure of compression wear available in the market and found that the pressure ranged 0.6-1.1 kPa for the ankle, 0.7-2.3 kPa for the calf, and 0.9-1.9 kPa for the thigh. Meanwhile, blood flow levels and rates significantly increased when participants wore CP-1, which had the highest clothing pressure level, and CP-2 and CP-4 with middle-level pressure. After exercise, CP-2's surface temperature was the highest and revealed that wearing CP-2 facilitated blood flow. CP-2 was evaluated as most positive in the sensibility assessment and showed a clothing pressure of 0.67-1.82 kPa; its pressure for the calf did not surpass 2.0 kPa. Considering positive physical effect of compression wear on blood flow and subjective psychological effect on participants, CP-2 (0.67-1.82 kPa) would have the most suitable clothing pressure level among other types of the wear in this study.

• 대한기계학회논문집B
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• 제29권11호
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• pp.1182-1188
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• 2005

An x-ray PIV (Particle Image Velocimetry) technique was developed to measure quantitative information on flows inside opaque conduits and on opaque-fluid flows. At first, the developed x-ray PIV technique was applied to flow in an opaque Teflon tube. To acquire x-ray images suitable for PIV velocity field measurements, refraction-based edge enhancement mechanism was employed using detectable tracer particles. The optimal distance between with the sample and detector was experimentally determined. The resulting amassed velocity field data were in reasonable agreement with the theoretical prediction. The x-ray PIV technique was also applied to blood flow in a microchannel. The flow pattern of blood was visualifed by enhancing the diffraction/interference -bas ed characteristic s of blood cells on synchrotron x-rays without any contrast agent or tracer particles. That is, the flow-pattern image of blood was achieved by optimizing the sample (blood) to detector distance and the sample thickness. Quantitative velocity field information was obtained by applying PIV algorithm to the enhanced x-ray flow images. The measured velocity field data show a typical flow structure of flow in a macro-scale channel.

• Korea-Australia Rheology Journal
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• 제20권4호
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• pp.189-196
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• 2008

The pulsatile flow of blood through a stenosed artery under the influence of external periodic body acceleration is studied. The effect of non-Newtonian nature of blood in small blood vessels has been taken into account by modeling blood as a Casson fluid. The non-linear coupled equations governing the flow are solved using perturbation analysis assuming that the Womersley frequency parameter is small which is valid for physiological situations in small blood vessels. The effect of pulsatility, stenosis, body acceleration, yield stress of the fluid and pressure gradient on the yield plane locations, velocity distribution, flow rate, shear stress and frictional resistance are investigated. It is noticed that the effect of yield stress and stenosis is to reduce flow rate and increase flow resistance. The impact of body acceleration is to enhance the flow rate and reduces resistance to flow.

• 한국전산유체공학회:학술대회논문집
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• 한국전산유체공학회 2011년 춘계학술대회논문집
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• pp.161-168
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• 2011

Cerebral aneurysm mostly occurs at a bifurcation of the circle of Willis. When the cerebral aneurysm is ruptured a disease like subarachnoid hemorrhage and stroke is caused and this can be even deadly for patients. Generally it is known that causes of the intracranial aneurysm are a congenital deformity of the artery and pressure or shear stress from the blood flow. A blood flow pattern and the geometry of the blood vessel are important factors for the aneurysm formation. Research for several hemodynamic indices has been performed and these indices can be used for the prediction of aneurysm initiation and rupture. Therefore, the numerical analysis was performed for hemodynamic characteristics of the blood flow through the cerebral artery applying the various bifurcation angle and flow rate ratio. We analyze the flow characteristics using indices from the results of the numerical simulation. In addition, to investigate the flow pattern in the aneurysm according to the bifurcation angle and the flow rate ratio, we performed the numerical simulation on the supposition that the aneurysm occurs.

• 한국가시화정보학회:학술대회논문집
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• 한국가시화정보학회 2006년도 추계학술대회 논문집
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• pp.121-124
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• 2006

The arteries are very important in cardiovascular system and easily adapt to varying flow and pressure conditions by enlarging or shrinking to meet the given hemodynamic demands. The blood flow in arteries is dominated by unsteady flow phenomena due to heart beating. In certain circumstances, however, unusual hemodynamic conditions cause an abnormal biological response and often induce circulatory diseases such as atherosclerosis, thrombosis and inflammation. Therefore quantitative analysis of the unsteady pulsatile flow characteristics in the arterial blood vessels plays important roles in diagnosing these circulatory diseases. In order to verify the hemodynamic characteristics, in-vivo measurements of blood flow inside the extraembryonic arterial bifurcation cascade of chicken embryo were carried out using a micro-PIV technique. To analyze the unsteady pulsatile flow temporally, the (low images of RBCs were obtained using a high-speed CMOS camera at 250fps with a spatial resolution of $30{\mu}m\times30{\mu}m$ in the whole blood vessels. In this study, the unusual flow conditions such as flow separation or secondary flow were not observed in the arterial bifurcations. However, the vorticity has large values in the inner side of curvature of vessels. In addition, the mean velocity in the arterial blood vessel was decreased and pulsating frequency obtained by FFT analysis of velocity data extracted in front of the each bifurcation was also decreased as the bifurcation cascaded.