• Title/Summary/Keyword: blood component

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Near-infrared Spectroscopic Measurement of Glucose Under the Existence of Other Major Blood Components (혈액의 주요 구성물질 존재 하에서 근적외분광분석법을 이용한 글루코오스 측정)

  • 백주현;강나루;우영아;김효진
    • YAKHAK HOEJI
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    • v.48 no.3
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    • pp.171-176
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    • 2004
  • This study was described for measuring clinically relevant levels of glucose in undiluted plasma and whole blood by near-infrared (NIR) spectroscopy. Result from an initial measurement of major blood components powder was over-lapped the absorption bands of glucose at 1500-1600 nm. However, the NIR data of blood components were clearly separated by principle component analysis (PCA) space. By the use of partial least squares (PLS) regression, glucose concentrations in undiluted plasma and whole blood could be determined with standard errors of prediction (SEP) of 15 mg/dl and 76 mg/dl, respectively. Although these blood components possessed strong absorption bands that overlapped with the absorption bands of glucose, successful calibration models could be carried out.

Influences of Chitosan, Sericin and Collagen Extract Complexes on the Improvement Actions of Lipid Component in Diabetes (키토산과 세리신 및 콜라겐 추출 혼합물이 당뇨의 혈당 및 지질성분 개선효과)

  • Kim, Han-Soo;Jang, Seong-Ho;Yoon, Myung-Joo;Choi, Woo-Seok;Kang, Jin-Soon
    • Journal of Environmental Science International
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    • v.20 no.8
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    • pp.1031-1039
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    • 2011
  • This study was conducted to examine the influences of chitosan, sericin and collagen extract complexes (1:1:1, w/w/w, CSC-F-005) in blood glucose and lipid concentrations in the sera of streptozotocin (STZ, 55 mg/kg BW, IP injection)-induced diabetic rats (SD strain) fed on experimental diets for 5 weeks. The concentrations of blood glucose, total cholesterol, HDL-cholesterol, ratio of HDL-cholesterol concentration to total cholesterol, atherosclerotic index, LDL-cholesterol, free cholesterol, cholesteryl ester, triglyceride (TG) and phospholipid (PL) in serum were effective on the metabolic regulation in diabetic rats. The activities of alkaline phosphatase (ALP) and aminotransferase (AST, ALT) in serum were lower in the extract complexes (CSC-F-005) than in the diabetic rats. The results shown above suggested that CSC-F-005 extract complexes supplementation effectively improvement of blood glucose and lipid components in the serum of STZ-induced diabetic rats.

The bibliographical study on the heamatic effects of Rehmanniae Radix (숙지황(熟地黃)의 효능(效能) 중 보혈작용(補血作用)에 대한 문헌적(文獻的) 연구(硏究))

  • Jeong, Deok-jin;Seo, Young Bae
    • Journal of Haehwa Medicine
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    • v.9 no.2
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    • pp.173-182
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    • 2001
  • 1. $\ll$Graphical Materia Medica$\gg$ is first book that writes about Rehmanniae Radix Preparat. $\ll$Shen nong's herbal$\gg$ is only written about Rehmanniae Radix. 2. After the $\ll$Decoction Materia Medica$\gg$, orintal dortors use Rehmanniae Radix's effect is removing heat from the blood and Rehmanniae Radix's effect is enriching the blood. 3. Rehmanniae Radix Preparat is kinds of durgs for enriching the blood, because Rehmanniae Radix Preparat's effect do nourishing yin and supplementing blood. Therefore, Rehmanniae Radix Preparat is uesd simple recipe or Rehmanniae Radix Preparat is used with another herbs that shows so good effect of hematogenous functions at laboratory work. 4. Bone marrow is doing hematogenesis. That has relation to Rehmanniae Radix Preparat's effect is replenishing bone marrow, it's channel tropisms are liver kidney channels. 5. Rehmanniae Radix Preparat's guide component is 5-HMF, but effective component has relation with hematogenesis is mannitol of saccharides. And we need more reserch about Rehmanniae Radix Preparat.

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An influence for the Choline-Esterase in Blood of the Canine following intake Scabby Barley (적미병감염맥류(赤黴病感染麥類)가 견혈액중(犬血液中)의 Choline-Esterase 에 미치는 영향(影響))

  • Kim, Dae Eun
    • Korean Journal of Veterinary Research
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    • v.4 no.1
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    • pp.15-17
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    • 1964
  • Scabby burley collected in Kyong Sang Nam Do fed to healthy dogs, age less than 2 years, old and determined the Choline-Esterase Activity in blood of dogs. The results obtained in this investigation are summarized as follows. 1. Choline-Esterase Activity in the blood of dogs fed Scabby barley has been decreased. 2. The poisionous component of the Scabby barley thought to be Anticholinesterase.

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Inventory Control Policies for a Hospital Blood Bank: A Simulation and Regression Approach (병원의 혈액 재고관리를 위한 평가 모형 : 시뮬레이션 및 회귀분석 방법)

  • Suh, Jeong-Dae
    • IE interfaces
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    • v.10 no.1
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    • pp.119-134
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    • 1997
  • The management of blood inventory is very important within the medical care system. The efficient management of blood supplies and demands for transfusions is of great economic and social importance to both hospitals and patients. For any blood type, there is a complex interaction among the optimal inventory level, daily demand level, daily supply level, transfusion to crossmatch ratio, crossmatch release period, issuing policy and the age of arriving units that determine the shortage and outdate rate. In this paper, we develop an efficient decision rule for blood inventory management in a hospital blood bank which can support efficient hospital blood inventory management using simulation. The primary use of the efficient decision rule will be to establish minimum cost function which consists of inventory levels, period in inventory, outdate and shortage rate for whole blood and various component inventories for a hospital blood bank or a transfusion service. If the administrator compute the mean daily demand for each blood type, the mean daily supply for each blood type, the length of the crossmatch release period and the average transfusion to crossmatch ratio, then it is possible to apply the efficient decision rule to compute the optimal inventory level, inventory period, outdate and shortage rate. This rule can also be used as a decision support system that allows the blood bank administrator to do sensitivity analysis related to controllable blood inventory parameters.

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Development of an Efficient Decision Rule for Blood Inventory Management (효율적인 혈액 재고 관리를 위한 결정룰의 도출)

  • 서정대
    • Journal of the Korea Society for Simulation
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    • v.5 no.1
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    • pp.13-27
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    • 1996
  • The management of blood inventory is very important within the medical care system. The efficient management of blood supplies and demands for transfusion is of great economic and social importance to both hospitals and patients. Fro any blood type, there is a complex interaction among the optimal inventory level, daily demand level , daily supply level, transfusion to crossmatch ratio, crossmatch release period, issuing policy and the age of arriving units that determine the shortage and outdate rate. In this paper, we develop an efficient decision rule for blood inventory management in a hospital blood bank which can support efficient hospital blood inventory management using simulation, The primary use of the efficient decision rule will be to establish minimum cost function which consists of inventory levels , period in inventory, outdate and shortage rate for whole blood and various component inventories for a hospital blood bank or a transfusion service, If the adminstrator compute the mean daily demand for each blood type, the mean daily supply for each blood type, the length of the crossmatch release period and the average transfusion to crossmatch ratio , then it is possible to apply the efficient decision rule to compute the optimal inventory level, inventory period , outdate and shortage rate. This rule can also be used as a decision support system that allows the blood bank adminstrator to do sensitivity analysis related to controlled blood inventory parameters.

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Effect of Inclusion of Chitosan-Oligosaccahariede in Drinking Water on the Blood Component Profile, Immunity and Antioxidative Enzyme in Broiler Chickens (키토산 올리고당의 음수내 급여가 육계의 혈액성상, 면역력 및 항산화 효소계에 미치는 영향)

  • Park, Seong-Bok;Kim, Sang-Woo;Kim, Young-Sin;Na, Chong-Sam;Shim, Kwan-Seob
    • Korean Journal of Organic Agriculture
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    • v.22 no.3
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    • pp.483-490
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    • 2014
  • The study was conducted to the effect of inclusion of chitosan-oligosaccharide in drinking water on the blood component profile, immunity and antioxidative enzyme of broiler chickens. A total of 28,000 broiler chickens (Arbor Acre) at 1 days of age were fed the commercial diet until 35 days of age, the treatment divided into two treatments, normal control group and chitosan-oligosaccharide in drinking water group. In concentration of glucose, treatment was significantly decreased than control (P<0.05), but not statistically different on the Triglyceride, Total cholesterol, HDL-cholesterol and LDL-cholesterol in the Blood component profile of broiler chicks. The concentration of glutamic oxalacetic transaminase (GOT) was statistically different but the concentration of glutamic pyruvate transaminase (GPT) was significantly decreased in treatment fed chitosan-oligosaccharide than control (P<0.05). Immunoglobullins in the blood, concentration of IgG was not significantly different among control and treatment but concentration of IgM was significantly increased in fed chitosan-oligosaccharide than control (P<0.05). Antioxidant and super oxide dismutase (SOD) was not different among control and treatment and concentration of catalase and glutathione peroxidase were significantly increased in fed chitosan-oligosaccharide than control (P<0.05).

The Studies of Component and Pharmacologic Action on Dianthus sinensis L. (구맥(瞿麥) Dianthus sinensis L.의 성분(成分) 및 약리작용(藥理作用)에 관(關)한 연구(硏究) ( I ))

  • Han, Dae-Sup;Ko, Kye-Chang;Jung, Jee-Chang
    • The Korean Journal of Pharmacology
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    • v.8 no.2
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    • pp.49-54
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    • 1972
  • The component and pharmacologic action on Dianthus sinensis L. were investigated as follows: 1) The components of Dianthus sinensis L. were suggested 8 kind of components by means of thin layer chromatography and paper chromatography. The one of them were suggested as a steroidal saponin by means of IR-spectrum and Liebermann-Burchard, Salkowiski, $SbCl_3$ reaction. 2) Sodium level in serum were reduced by administration of the sample to the rabbits, while in urine were elevated. 3) Blood sugar level of normal rabbits administered with sample, no significant variation were detected. 4) When the hyperglycemic rabbits treated with alloxan were administered sample, blood-sugar level were significantly decreased than control group.

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Bifidus Fermentation Increases Hypolipidemic and Hypoglycemic Effects of Red Ginseng

  • Trinh, Hien-Trung;Han, Sang-Jun;Kim, Sang-Wook;Lee, Young-Chul;Kim, Dong-Hyun
    • Journal of Microbiology and Biotechnology
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    • v.17 no.7
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    • pp.1127-1133
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    • 2007
  • Antihyperlipidemic and antihyperglycemic effects of Red Ginseng (RG, steamed and dried root of Panax ginseng C.A.Meyer, family Araliaceae), major component of which is ginsenoside Rg3, and Bifidodoterium-fermented RG (FRG), major component of which is ginsenoside Rh2, were investigated. Orally administered RG and FRG potently reduced the serum triglyceride levels in com-oil-induced hypertriglycemidemic mice as well as total cholesterol and triglyceride levels in Triton WR-1339-induced hyperlipidemic mice. Of the saponin and polysaccharide fractions of RG and FRG, the polysaccharide fraction inhibited postprandial blood glucose elevation of maltose- or starch-loaded mice and reduced the blood triglyceride levels in com-oil-induced hypertriglycemidemic mice. The saponin fraction and its ginsenosides Rg3 and Rh2 reduced blood triglyceride and total cholesterol levels in Triton WR1339-induced hyperlipidemic mice. The inhibitory effect of FRG and its main constituents against hyperlipidemia and hyperglycemia in mice were more potent than those of RG. These findings suggest that hypolipidemic and hypoglycemic effects of RG can be enforced by Bifidus fermentation and FRG may improve hyperlipidemia and hyperglycemia.

Effect of Propolis on Blood Components and Tissues of Mouse after Low dose X-ray Irradiation

  • Ji Tae-Jeong;Min Byung-In;Seo Eul-Won
    • Biomedical Science Letters
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    • v.12 no.1
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    • pp.43-48
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    • 2006
  • Present study aimed to investigate recovering effect of propolis on blood components and tissues of mouse after low dose irradiation. It is verified that the contents of Fe, Mg, P, Zn and Cu in propolis dosed blood are increased slightly than irradiated blood, however, the contents of Ba and Pb are decreased to one tenth than irradiated blood and the contents of Fe and P are increased to 10% than control group. We consider this result as the propolis acts a role of defence factor minimizing changes of elements caused by irradiation in blood. Among the blood components, Glutamate oxaloacetate transaminase (GOT) value is increased after the radiation but after dosed with propolis and irradiated the value is decreased, suggesting that propolis as a buffering material against irradiation. After dosed with propolis, a number of spermatogenic cells are lowered in testis tissue, however, nucleus and cytoplasm are clearly observed in spermatogonia, spermatocytes and spermatid cells. And nucleus and membrane of cells in the proximal convoluted tubule of renal tissue are clearly observed. Also, cytoplasmand membrane of surface mucous cells in stomach tissue are appeared in normal which is almost like those of control group. We consider that the propolis used in this study is preventing deformations of cells increasing resistance capacity against irradiation rather than recovering damaged tissues.

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