• Title/Summary/Keyword: blockage ratio

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Effects of Caffeine on Auditory- and Vestibular-Evoked Potentials in Healthy Individuals: A Double-Blind Placebo-Controlled Study

  • Tavanai, Elham;Farahani, Saeid;Ghahraman, Mansoureh Adel;Soleimanian, Saleheh;Jalaie, Shohreh
    • Korean Journal of Audiology
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    • v.24 no.1
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    • pp.10-16
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    • 2020
  • Background and Objectives:The blockage of adenosine receptors by caffeine changes the levels of neurotransmitters. These receptors are present in all parts of the body, including the auditory and vestibular systems. This study aimed to evaluate the effect of caffeine on evoked potentials using auditory brainstem responses (ABRs) and cervical vestibular-evoked myogenic potentials (cVEMPs) in a double-blind placebo-controlled study. Subjects and Methods: Forty individuals (20 females and 20 males; aged 18-25 years) were randomly assigned to two groups: the test group (consuming 3 mg/kg pure caffeine powder with little sugar and dry milk in 100 mL of water), and the placebo group (consuming only sugar and dry milk in 100 mL water as placebo). The cVEMPs and ABRs were recorded before and after caffeine or placebo intake. Results: A significant difference was observed in the absolute latencies of I and III (p<0.010), and V (p<0.001) and in the inter-peak latencies of III-V and I-V (p<0.001) of ABRs wave. In contrast, no significant difference was found in cVEMP parameters (P13 and N23 latency, threshold, P13-N23 amplitude, and amplitude ratio). The mean amplitudes of P13-N23 showed an increase after caffeine ingestion. However, this was not significant compared with the placebo group (p>0.050). Conclusions: It seems that the extent of caffeine's effects varies for differently evoked potentials. Latency reduction in ABRs indicates that caffeine improves transmission in the central brain auditory pathways. However, different effects of caffeine on auditory- and vestibular-evoked potentials could be attributed to the differences in sensitivities of the ABR and cVEMP tests.

Hydrologic Utilization of Radar-Derived Rainfall (I) Optimal Radar Rainfall Estimation (레이더 추정강우의 수문학적 활용 (I): 최적 레이더 강우 추정)

  • Bae Deg-Hyo;Kim Jin-Hoon;Yoon Seong-Sim
    • Journal of Korea Water Resources Association
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    • v.38 no.12 s.161
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    • pp.1039-1049
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    • 2005
  • The objective of this study is to produce optimal radar-derived rainfall for hydrologic utilization. The ground clutter and beam blockage effects from Mt. Kwanak station (E.L 608m) are removed from radar reflectivities by POD analysis. The reflectivities are used to produce radar rainfall data in the form of rain rates (mm/h) by the application of the Marshall-Palmer reflectivity versus rainfall relationship. However, these radar-derived rainfall are underestimated in temporal and spatial scale compared with observed one, so it is necessary to hire a correction scheme based on the gauge-to-radar (G/R) statistical adjustment technique. The selected watershed for studying the real-time correction of radar-rainfall estimation is the Soyang dam site, which is located approximately 100km east of Kwanak radar station. The results indicate that adjusted radar rainfall with the gauge measurement have reasonal G/R ratio ranged on 0.95-1.32 and less uncertainty with that mean standard deviation of G/R ratio are decreased by $9-28\%$. Mean areal precipitation from adjusted radar rainfall are well agreed to the observed one on the Soyang River watershed. It is concluded that the real-time bias adjustment scheme is useful to estimate accurate basin-based radar rainfall for hydrologic application.

A Study on the Influence of S Shaped Annular Duct on the Centrifugal Compressor Performance (S자형 환형덕트가 원심압축기 성능에 미치는 영향에 관한 연구)

  • 정주현;전승배;김승우
    • Journal of the Korean Society of Propulsion Engineers
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    • v.2 no.2
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    • pp.64-73
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    • 1998
  • In twin spool aero-engine, there may be a S shaped annular duct between high pressure and low pressure spools. The flow passing this S shaped duct experiences the flow acceleration and deceleration due to the convex and concave surface of the duct as well as the increase of blockage according to the boundary layer growth along the surfaces. So, the high pressure compressor which is located behind the S shaped duct is influenced by the non-uniform flow field generated by the geometry of inlet duct. To study the influence of the S shaped duct on the centrifugal stage, performance tests were implemented for the compressor with straight cylindrical inlet duct and with S shaped inlet duct, respectively. The test results showed that the performance, such as pressure ratio and efficiency, of the compressor with S shaped duct was worse than that of the compressor with cylindrical duct. And the compressor with S shaped duct had reduced maximum flow rate around design speed. To investigate the cause of performance degradation, flow anlaysis was performed for the impeller in front of which is located S shaped annular duct. The result of CFD showed the strong acceleration of the flow in the axial direction around the inducer tip region which caused the increase of relative mach number and the decrease of incidence angle of the flow.

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A comparative study of field measurements of the pressure wave with analytical aerodynamic model for the high speed train in tunnels (고속철도 터널내 압력파 측정과 공기압 해석모델에 대한 기초연구)

  • Kim, Hyo-Gyu;Choi, Pan-Gyu;Hong, Yoo-Jung;Yoo, Ji-Oh
    • Journal of Korean Tunnelling and Underground Space Association
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    • v.17 no.3
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    • pp.319-332
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    • 2015
  • The pressure wave formed by the piston effects of the train proceeds within the tunnel when a train enters the tunnel with a high speed. Depending on the condition of tunnel exit, the compression waves reflect at a open end, change to the expansion waves, transfer to tunnel entrance back. Due to interference in the pressure waves and running train, passengers experience severe pressure fluctuations. And these pressure waves result in energy loss, noise, vibration, as well as in the passengers' ears. In this study, we performed comparison between numerical analysis and field experiments about the characteristics of the pressure waves transport in tunnel that appears when the train enter a tunnel and the variation of pressure penetrating into the train staterooms according to blockage ratio of train. In addition, a comparative study was carried out with the ThermoTun program to examine the applicability of the compressible 1-D model(based on the Method of Characteristics). Furthermore examination for the adequacy of the governing equations analysis based on compressible 1-D numerical model by Baron was examined.

The Effects of the Biodiversity Increase after Creation of the Artificial Wetland -The Case of Ecological Pond at Seoul Technical High School- (인공습지 조성후 생물다양성 증진 효과에 관한 연구 -서울공고 생태연못을 중심으로-)

  • 김귀곤;조동길
    • Journal of the Korean Institute of Landscape Architecture
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    • v.27 no.3
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    • pp.1-17
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    • 1999
  • The purpose of this study is to evaluate the creation techniques of artificial wetland, one of biotopes developed to promote biodiversity in urban areas, and to look for improvement steps. Specifically, artificial wetland creation techniques were categorized into living environment and living creature classification. Being living conditions for creations, habitat environment was reviewed with a focus on water and soil environments. Living creatures were classified into plants, insects, fish, and birds. The evaluation of creation techniques was done in post-construction evaluation while considering the creation of habitats for living creatures. Intervention by users, changes in living environment and living species, and relevance of creation techniques were reviewed. Key results of this study are as follows. (1) Water environment for the living environment of creatures provides a suitable environment conditions for the living of creatures through a process easing the use of piped water. Various water depths and embankment appear to have a positive impact on the living of aquatic life. In particular, embankment covered in soil naturally played an important role as a place for the activities of aquatic insects and young fish as well as the growth of aquatic plants. (2) Various aquatic and ground plants to promote insect-diversity, shallow water, and old-tree logs had contributed greatly in increasing the types and number of insects. Aquatic insects. Aquatic insects were seen much particularly in areas where aquatic plants are rich but water is shallow than any other areas. (3) A space piled with stone to provide habitats for fish was not much used. However, it was observed that fish used embankment built with natural stones and embankment using logs in areas where water is deep. In addition, it was confirmed that 1,500 fish that had been released propagated using various depths and places for birth. (4) It was analyzed that techniques (creation of island, log setting, and creation of man-made bird nests) to provide habitats and to attract birds are not serving their roles. In such a case, it is believed that species had not increased due to the smallness as well as isolated features of the area. Based on theoretical review, they are judged to be areas that are likely to be used when a greater variety of birds is introduced. It is judged that attracting and keeping more birds at the site, such spaces need to be linked systematically in the future in terms of building eco-network while ensuring an adequate living areas. (5) In the study areas, users intervened greatly. As a result, a blockage was created preventing the normal growth of plants and non-indigenous plants were introduced. In order to limit the intervention by users, setting enough buffer zones, and environment education programs were urgently required. D/H=1>Hyangkyo> houses on the river>temples>lecture halls. D/H ratio of the backside areas is as follows. D/H=1>Hyangkyo>houses on the river>lecture halls. 4. Inner garden were planted deciduous than evergreen trees with Lagerstroemia indica. Enclosed dominant trees were planted by Pinus densiflora, Querces seuata. construct GEM strain, and examined for the expression and functional stability in microcosms.

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Stabilization Characteristics of the Diffusion Flame Formed in the Wake of Bluff Body with Fuel Injection (연료분출을 수반하는 보염기 후류에 형성되는 확산화염의 보염특성)

  • 안진근
    • Journal of Energy Engineering
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    • v.10 no.3
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    • pp.223-232
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    • 2001
  • To study the stabilization characteristics of diffusion flame formed in the wake of a cylindrical bluff body with fuel injection, the flame stability limits, length and temperature of recirculation zone of flame, turbulence intensity distribution near the recirculation zone of flame were measured and analyzed. The length of recirculation zone is independent on main fuel injection quantity, but it is dependent on fuel injection angles, air stream velocity, and auxiliary fuel injection into recirculation zone. For diffusion flame, in general, the flame stabilization is deteriorated with increase of he length of recirculation zone, but if the turbulence generator is installed, the flame stabilization is improved with increase of the length of recirculation zone. The temperature of recirculation zone is dependent on fuel injection angles, auxiliary fuel injection into recirculation zone, turbulence generators, and it dependent on fuel injection angles, auxiliary fuel injection into recirculation zone, turbulence generators, and it has a maximum value at the condition of each theoretical mixture. In general, the more temperature of recirculation zone is low, the more flame is stable. But when the turbulence generator is installed, the more temperature of recirculation zone is low, the more flame is unstable. The turbulence intensity in the wake of bluff body is increased with increase of diameter or blockage ratio of grid. The more turbulence intensity is increased by installation of turbulence generator, the more flame is unstable. Finally, It is clear that the stabilization characteristics of diffuser flame can be controlled by some parameters such as fuel injection angles, auxiliary fuel injection into recirculation zone, turbulence generators.

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Road Runoff Treatment using Pilot Scale-NPS Treatment Plant Filling up Expended Polypropylene Media (발포고분자여재가 충전된 파일럿 규모의 비점오염물질 처리장치를 이용한 도로 강우유출수 처리)

  • Kim, Seogku;Oh, Hyecheol;Ahn, Jaehwan
    • Journal of Korean Society of Environmental Engineers
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    • v.36 no.10
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    • pp.711-718
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    • 2014
  • Investigated the processing characteristics of the pollutants and runoff due to storm events in the actual application of the road fields and a Non-Point Sources (NPS) pilot scale equipment. This phenomenon has occurred in the influent bypass the blockage occurs after 90 min the expended polymeric media was filled with filtered column. When entering a treatment tank SS 200 mg/L or more high concentration of effluent treatment efficiency was reduced from the reaction time 60 min. Influent concentration less then SS 180 mg/L was stable handling. The $COD_{Cr}/SS$ ratio were analyzed with 0.67, median value. Showed 92.1% and 82.3% respectively with an average removal rate of the SS and the $COD_{Cr}$. If the influent concentration of TP is the 0.5 mg/L or less, the quality of the treated water is 0.1 mg/L levels were expressed in a stable process. And when entering the 1.0 mg/L or more of the treated water, had a greater than average 0.2 mg/L. If the influent concentration of TN is 4~10 mg/L, the treatment water quality level was kept a 1.5~3.0 mg/L. The average removal efficiency of TP and TN respectively 73.9%, 50.4%.

Baicalein induces cell death in Human Lung Carcinoma A549 Cells: Role of Apoptosis and Autophagy pathway (인체폐암 A549 세포에서 Baicalein에 의한 세포사멸 유도: Apoptosis와 Autophagy 경로의 역할)

  • Kim, Chul Hwan;Hwang, Buyng Su;Jeong, Yong Tae;Kim, Min-Jin;Shin, Su Young;Oh, Young Taek;Eom, Jung Hye;Lee, Seung Young;Choi, Kyung Min;Cho, Pyo Yun;Jeong, Jin-Woo
    • Proceedings of the Plant Resources Society of Korea Conference
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    • 2019.04a
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    • pp.112-112
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    • 2019
  • Baicalein is one of the main flavonoids derived from roots of Scutellaria baicalensis Georgi, a traditional Oriental medicine. Although baicalein has high antitumor effect on several human carcinomas, the mechanism responsible for this property is not unclear. In this study, the data revealed that baicale-ininduced growth inhibition was associated with the induction of apoptosis connecting with cytochrome c release, down-regulation of anti-apoptotic Bcl-xl and increased the percentage of cells with a loss of mitochondria membrane permeabilization. Baicalein also induced the proteolytic activation of caspases and cleavage of PARP; however, blockage of caspases activation by z-VAD-fmk inhibited baicalein-induced apoptosis. In addition, baicalein enhanced the formation of autophagosomes and up-regulated LC3-II/LC3-I ratio. Interestingly, the pretreatment of bafilomycin A1 recovered baicalein-induced cell death suggesting that autophagy by baicalein roles as protective autophagy. Taken together, our results indicated that this flavonoid induces apoptosis and cell protective autophagy. These data means combination treatment with baicalein and autophagy inhibitor might be a promising anticancer drug.

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A Study on Mechanical Properties and Applicability of CNT-Mixed Grout (CNT-Mixed grout의 역학적 특성 및 적용성 연구)

  • Kim, Seunghyun;Kim, Kanghyun;Shin, Jongho
    • Journal of the Korean GEO-environmental Society
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    • v.23 no.9
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    • pp.5-16
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    • 2022
  • In recent years due to the development of urban and underground space, the number of ground disasters is increasing, and it is also leading to social problems. To solve the problem, a grouting method is generally used. However, the grouting method has material (grout) limitations in permeability, gelation properties and tensile resistance. Therefore, research on grout materials mixed with fibers is actively carried out to improve the problems. However, in the actual ground injection process, many difficulties have been faced causing the blockage of the inlet port and the injection tube. In this study, 'CNT-mixed grout material' was developed using CNT powder that can reinforce the tensile strength of soils. The uniaxial compressive and tensile strength tests were performed to obtain the optimal content and mechanical properties of the CNT Powder-mixed grout. It was found that the optimal CNT powder content is 0.5% that gives the average maximum strength. A one-dimensional injection test and the bulb formation test were carried out, and it was identified that the injection rate and bulb form could be controlled by pressure and mixing ratio. Field application of the CNT-Mixed grout is simulated using numerical analysis of slopes, foundations, and tunnels reinforced in several types. The positive effect of reducing plastic ranges and settlements was confirmed.