• 대한전기학회:학술대회논문집
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• 대한전기학회 2005년도 학술대회 논문집 정보 및 제어부문
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• pp.484-486
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• 2005

Passenger safety is a primary concern of railway system but, it has been urgent issue that dozens of people are killed every year when they falloff from train platforms. Recently, advancements in IT have enabled applying vision sensors to railway environments, such as CCTV and stereo camera sensors. In this paper, we propose a stereoscopic video coding scheme for subway accident monitoring system. The proposed scheme is designed for providing flexible video among various displays, such as control center, station employees and train driver. We uses MPEG-2 standard for coding the left-view sequence and IBMDC for predicting the P- and B-types of frames of the right-view sequence. IBMDC predicts matching block by interpolating both motion and disparity predicted macroblocks. To provide efficient stereoscopic video service. we define both temporally and spatially scalable layers for each eye's-view by using the concept of Spatio-Temporal scalability. According to the experimental results. we expect the proposed functionalities will play a key role in establishing highly flexible stereoscopic video codec for ubiquitous display environment where devices and network connections are heterogeneous.

• 제어로봇시스템학회:학술대회논문집
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• 제어로봇시스템학회 1989년도 한국자동제어학술회의논문집; Seoul, Korea; 27-28 Oct. 1989
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• pp.675-681
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• 1989

As an adaptive control function generator, the CMAC (Cerebellar Model Arithmetic or Articulated Controller) based learning control has drawn a great attention to realize a rather robust real-time manipulator control under the various uncertainties. There remain, however, inherent problems to be solved in the CMAC application to robot motion control or perception of sensory information. To apply the CMAC to the various unmodeled or modeled systems more efficiently, It is necessary to analyze the effects of the CMAC control parameters an the trained net. Although the CMAC control parameters such as size of the quantizing block, learning gain, input offset, and ranges of input variables play a key role in the learning performance and system memory requirement, these have not been fully investigated yet. These parameters should be determined, of course, considering the shape of the desired function to be trained and learning algorithms applied. In this paper, the interrelation of these parameters with learning performance is investigated under the basic learning schemes presented by authors. Since an analytic approach only seems to be very difficult and even impossible for this purpose, various simulations have been performed with prespecified functions and their results were analyzed. A general step following design guide was set up according to the various simulation results.

• BMB Reports
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• 제41권4호
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• pp.278-286
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• 2008

Angiogenesis, the formation of blood vessels, is essential for preparing a closed circulatory system in the body, and for supplying oxygen and nutrition to tissues. Major diseases such as cancer, rheumatoid arthritis, and atherosclerosis include pathological angiogenesis in their malignant processes, suggesting anti-angiogenic therapy to be a new strategy for suppression of diseases. However, until the 1970s, the molecular basis of angiogenesis was largely unknown. In recent decades, extensive studies have revealed a variety of angiogenic factors and their receptors, including vascular endothelial growth factor (VEGF)-VEGFRs, Angiopoietin-Tie, Ephrin-EphRs and Delta-Notch to be the major regulators of angiogenesis in vertebrates. VEGF and its receptors play a central role in physiological as well as pathological angiogenesis, and functional inhibitors of VEGF and VEGFRs such as anti-VEGF neutralizing antibody and small molecules that block the tyrosine kinase activity of VEGFRs have recently been approved for use to treat patients with colorectal, lung, renal and liver cancers. These drugs have opened a novel field of cancer therapy, i.e. anti-angiogenesis therapy. However, as yet they cannot completely cure patients, and cancer cells could become resistant to these drugs. Thus, it is important to understand further the molecular mechanisms underlying not only VEGF-VEGFR signaling but also the VEGF-independent regulation of angiogenesis, and to learn how to improve anti-angiogenesis therapy.

• 대한의용생체공학회:학술대회논문집
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• 대한의용생체공학회 1997년도 추계학술대회
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• pp.154-160
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• 1997

By their rapid and periodic actions, the cilia of the human respiratory tract play an important role in clearing inhaled noxious particles. Based on the automated image-processing technique, we studied ciliary beat frequency (CBF) objectively and quantitatively. Microscopic ciliary images were transformed into digitized gray ones through an image-grabber, and from these we extracted signals or CBF. By means of a FFT, maximum peak frequencies were detected as CBFs in each partitioned block or the entire digitized field. With these CBFs, we composed distribution maps visualiy showing the spatial distribution of CBFs. Through distribution maps of CBF, the whole aspects of CBF changes or cells and the difference of CBF of neighboring cells can be easily measured and detected. Histogram statistics calculated from the user-defined polygonal window can show the local dominant frequency presumed to be the CBF of a cell or a crust the region includes.

• 한국기계연구소 소보
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• 통권19호
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• pp.125-139
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• 1989

As an adaptive control function generator, the CMAC (Cerebellar Model Arithmetic or Articulated Controller) based learning control has drawn a great attention to realize a rather robust real-time manipulator control under the various uncertainties. There remain, however, inherent problems to be solved in the CMAC application to robot motion control or perception of sensory information. To apply the CMAC to the various unmodeled or modeled systems more efficiently, it is necessary to analyze the effects of the CMAC control parameters on the trained net. Although the CMAC control parameters such as size of the quantizing block, learning gain, input offset, and ranges of input variables play a key role in the learning performance and system memory requirement, these have not been fully investigated yet. These parameters should be determined, of course, considering the shape of the desired function to be trained and learning algorithms applied. In this paper, the interrelation of these parameters with learning performance is investigated under the basic learning schemes presented by authors. Since an analytic approach only seems to be very difficult and even impossible for this purpose, various simulations have been performed with pre specified functions and their results were analyzed. A general step following design guide was set up according to the various simulation results.

• Animal cells and systems
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• 제6권4호
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• pp.327-333
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• 2002

Among the silk glands in the black widow spider Latrodectus mactans, the ampullate one is the most predominant gland in both sexes, and is com-posed of three functional parts - excretory duct, storage ampulla and convoluted tail regions. This experiment was performed using mechanical pulling stimulation with electric motor equipment to reveal a correlation between silk usage and silk producing system in this poisonous spider. The mature secretory products in glandular epithelium are closely packed and appear as electron-opaque spherical vesicles. A part of the vesicles with fine fibrillar paracrystalline texture seems to store some proteins which will function at the time of final assembly into fibrils. Most of the secretory silk products which originated from the rough endoplasmic reticula of the glandular epithelial cells are grown by fusion with surrounding small vesi-cles. However, the Golgi complex does not seem to play an important role in this process of secretion. According to progressive maturation of secre-tory silk product, these granules are progressively filled with a fine fibrillar material, and thus appear much more electron-dense than those of earlier states. When the secretory product is extruded from the glandular cavity, the epithelium is rapidly changed to a thinner layer of tall columnar cells with less definitive cell membranes. After extruding there ave a few secre-tory droplets within these cells, thus causing this region to stain much lighter.

• 한국미생물학회:학술대회논문집
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• 한국미생물학회 2000년도 추계학술발표대회
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• pp.66-77
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• 2000

For a variety of viruses, the primary virus infection has been shown to prevent superinfection with a homologous secondary virus; however, the mechanism of exclusion has not been clearly understood. In this work, we demonstrated that BVDV -infected MDBK cells were protected from superinfection with a homologous superinfecting BVDV, one of the positive-sense RNA pestiviruses, but not with an unrelated rhabdovirus, such as vesicular stomatitis virus. Once superinfection exclusion was established by a primary infection with BVDV, the transfected infectious BVD viral RNA genome was shown to be competent for viral translation, but not viral replication. In addition, our results also demonstrated that upon superinfection, the. viral RNA genome of viral particles was not transferred into the cytoplasm of BVDV -infected cells. Using newly developed system involving rapid generation of the MDBK cells expressing BVD viral proteins, we subsequently found that expression of the viral structural proteins was dispensable for the block occurring at the level of viral RNA replication, but required for the exclusion at the level of viral entry step. Altogether, these findings provide evidence that the superinfection exclusion of BVDV occurs not only at the level of viral replication in which the viral replicase are involved, but also at the level of viral entry with which the viral structural proteins are associated, and that a cellular factor(s) play an essential role in this process.

• 한국실내디자인학회논문집
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• 제15권3호
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• pp.201-210
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• 2006

Among the architects who use diagrams as a digital design process, especially through Peter Eisenman and Ben van Berkel's works, we have specifically got the meaning of their diagrams. Their diagrams act as 'the block of becoming' and we can regard the diagrams not only as a tool of devenir including architect's root thoughts beyond a tool of schematic presentation, but also as architect's intention including devenir thought. And in the case of diagrams which the architects use, we can recognize that architects' intentions are to think that Deleuze's 'machine abstraite' evolve the diagram into various and transformed form. That is to say, Peter Eisenman interprets the machine abstraite as a root thought of devenir by using diagram as medium to reveal the virtual. And Ben van Berkel transforms the diagram by including all external conditions into selected diagram which shows the abstract relations to the elements. We can get the meaning of the machine abstraite from these cases well. This study will play an important role in giving good usage of the diagram in making a form of contemporary digital architecture and showing the direction of form creation field.

• Animal cells and systems
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• 제4권4호
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• pp.367-373
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• 2000

In the present study we determined if NELL2, a neural tissue-specific protein containing 6 epidermal growth factor (EGF)-like repeat domains, plays an important role in the regulation of puberty initiation in the rat hypothalamus. We origin811y found that NELL2 is a new estrogen-responsive gene in hypothalami derived from estrogen-sterilized and control rats using a PCR differential display. In the 40-day-old female rat hypothalamus, NELL2 was up-regulated by neonatal estrogen treatment. In situ hybridization histochemistry showed that NELL2 is very abundant in the ventromedial hypothalamic nucleus that is responsible for the control of sex behavior. NELL2 mRNA level in the medial basal hypothalamus showed a dramatic increase before female puberty onset, which suggests that NELL2 may be involved in the process regulating female puberty onset. We attemped to block NELL2 synthesis with intracerebroventricular injection of an antisense oligodeoxynucleotide (ODN) to the NELL2 mRNA, and examined its effect on the puberty onset of the female rat. The antisense ODN significantly delayed puberty initiation determined by vaginal opening. In summary, NELL2 may play an important role in the regulation of female puberty onset.

• 한국자원식물학회:학술대회논문집
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• 한국자원식물학회 2019년도 춘계학술대회
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• pp.61-61
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• 2019

In any crop breeding program Selection and use of genetically diverse genotypes to develop cultivars with a broad genetic base is important. Molecular markers play a major role in selecting diverse genotypes. Molecular breeding programs of the crop can be made more efficient by use of molecular markers. The present study was done with an aim of analyzing genetic diversity and the population structure in 24 accessions of sunflower (Helianthus annus L.) from Kenya genetic diversity using 35 EST-SSR and gSSR primers.Out of the 35 markers 3 were not polymorphic as they indicated Polymorphic Information content( PIC) of value 0.00 and so the data analysis was done using 32 markers . The 32 set of markers used produced 29 alleles ranging from 2 to 7with a mean of 3.0 alleles per locus.The average value of polymorphic information contents(PIC) were 0.3 .Genetic diversity analysis using these markers revealed 3 major clusters. This result could be useful for designing strategies to make elite hybrid and inbreeding of crossing block for breeding and future molecular breeding programs to make elite variety.