• 제목/요약/키워드: biological stability

검색결과 844건 처리시간 0.031초

파이로 공정 세라믹 폐기물을 위한 처분용기의 설계, 제작 방안, 그리고 기능 평가 (Design, Manufacturing, and Performance estimation of a Disposal Canister for the Ceramic Waste from Pyroprocessing)

  • 이민수;최희주;이종열;최종원
    • 방사성폐기물학회지
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    • 제10권3호
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    • pp.209-218
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    • 2012
  • 현재 한국원자력연구원에서는 국내에 축적된 사용후핵연료 문제를 해결하기 위해서 건식재처리공정(pyroprocess)을 개발 중에 있다. 건식재처리 공정에서는 상당량의 고준위 염폐기물이 발생되며, 이는 곧 세라믹 결합제로 고화된다. 고화된 세라믹 폐기물은 안전한 금속 처분용기에 밀폐된 후, 인간생활환경과 격리될 예정이다. 본문에서는 고준위 세라믹폐기물을 처분하기 위한 처분용기의 개발에 관한 전반적인 내용을 다루고 있으며, 특히 처분용기의 설계 요건, 용기의 구성, 용기의 제작, 용기의 부식저항성, 방사선 차폐, 구조적 안전성 등에 대해 논의하고자 한다. 완성된 처분용기는 오랜 기간 동안 방사성 핵종의 누출이 없이 열적, 기계적, 화학적, 생물학적 공격에도 안전한 것을 목적으로 한다.

생체분해성 고분자의 합성 및 물성에 관한 연구(II) -Poly (L-lactic acid-co-glycine-L-lactic acid) 와 Poly- (L-lactic acid-co-glycine-L-methyl lactic acid) (Synthesis and Characterization of Poly(L-lactic acid-co-glycine-L-lactic acid) and Poly - ( L-1actic acid-co-gl ycine-L-methyl 1actic acid))

  • 성용길;송대경;박경희
    • 대한의용생체공학회:의공학회지
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    • 제9권2호
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    • pp.225-232
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    • 1988
  • Poly (L- lactic acid-co-glycine-L-lactic acid) and Poly (L-lactic acid-co-glycine-L- methyl lactic acid ) have been prepared by ring opening polymerization. The monomer 6, 6-dimethyl morpho-line-2, 5-dione was synthesized by the bromoisobutylation of 2-bromoisobutyryl bromide with glycin e. L-lactide, 6-methyl morpholine-2, 5-diode. and 6, 6-dimethyl morpholine-2, 5-diode have been used as starting materials for polydepsipeptides. The synthesized monomers and copolymers have been identified by NMR and FT-lR spa- ctrophotometer. The thermal propert ies and glass transition temperature(Tg) of the copolymers have been measured by differential scanning calorimetry. The Tg values of poly(L-lactic acid co-glycine-L-lactic acid) system are increased from $53^{\circ}C\; to\; 107^{\circ}C$ with increasing the mole fraction of 6-methyl morpholine-2, 5-diode. And the Tg values of poly(L-lactic acid co-glycine-L-methyl lactic acid) system are increased from $53^{\circ}C\;to\;138^{\circ}C$ with increasing the mole fraction of 6. 6-dimethyl morpholine-2, 5-diode The thermal stability of poly (L-lactic acid-co-glycine-L-methyl lactic acid) is slightly greta text than that of poly(L-lactic acid-co-glycine-L-lactic acid) due to the methyl group.

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실리콘러버 지지체의 $K^+$$Na^+$ 선택성 고체형 전극을 이용한 자동혈액분석기의 개발에 대한 연구 (Studies on the Development of the Automatic Blood Analyzer with Silicone Rubber-Based Solid-State $K^+$- and $Na^+$-Selective Electrodes)

  • 강명성;전우성;김선관;김대훈;차근식;남학현;조한익;박성섭
    • 대한의용생체공학회:학술대회논문집
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    • 대한의용생체공학회 1995년도 추계학술대회
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    • pp.26-33
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    • 1995
  • Silicone Rubber (SR)-based potassium- and sodium-selective solid-state electrodes have been developed for the portable blood electrolyte analyzer system. The electrochemical performance of these electrodes have been evaluated with a static experimental setup and with the newly developed blood electrolyte analyzer system (model; HS603). It has been shown that their potentiometric properties are essentially comparable to those of PVC-based ion-selective electrodes, but with greatly improved lifetime (200 and 40 days for potassium and sodium sensors, respectively) and potential stability (within $\pm0.1$ mV). Clinical tests have been performed with real serum samples and the results have been compared with those obtained from Ciba-Corning BGA 288 system; correlations were excellent, proving its practical utility as a new commercial system.

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N-Acetyl-D-glucosamine (NAG)의 피부주름 개선 효과 (Anti-wrinkle Effect of N-Acetyl-D-glucosamine (NAG))

  • 김광수;최근호;최장우;최준학;한송희;남상윤;이승화
    • 대한화장품학회지
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    • 제30권4호
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    • pp.457-462
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    • 2004
  • N-Acetyl-D-glucosamine (NAG)는 보습제로 사용되어지는 히아루론산의 구성물질인 뮤코 다당류의 일종이며, 특히 화장품으로서 응용은 보습제로서의 사용이 최초이다. 본 실험에서는 게나 새우의 껍데기에서 추출된 키틴을 탈아세틸화 하여 얻은 NAG를 화장품 원료로서 적용하고자 하였다. 현재 기능성 주름 원료로 알려진 레티놀(retinol)과 NAG를 비교하기 위하여 섬유아세포의 활성능력 및 콜라겐 생성촉진 효과를 비교 실험하였으며, 제형 내에서의 안정성을 위하여 HPLC로 역가를 측정하였다. 실험결과, 게의 껍질로부터 유도된 NAG는 피부에 자극을 전혀 주지 않으면서 섬유아세포의 세포활성 및 콜라겐의 생성을 촉진시키는 효과를 나타내었으며, 헤어리스 마우스를 대상으로 실험을 실시한 결과 피부층의 변화를 통하여 주름의 감소 효능을 볼 수 있었다.

ECOLOGICAL RESPONSE OF STREAMS IN KOREA UNDER DIFFERENT MANAGEMENT REGIMES

  • Lee Chang-Seok;Cho Yong-Chan;Shin Hyun-Cheol;Moon Jeong-Suk;Lee Byung-Cheon;Bae Yang-Seop;Byun Hwa-Geun;Yi Hoon-Bok
    • Water Engineering Research
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    • 제6권3호
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    • pp.131-147
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    • 2005
  • Today, a trend that tries to return the artificial space of a river to a natural one is expanding. But in Korea, which lies in the monsoon climate zone, rivers endure flood damage every year. Moreover, climatic change from global warming causes severe variations in precipitation patterns. Until recently, river restoration practices in Korea have followed partial restoration. These restorative treatments transformed artificial structures of the stream to natural ones and introduced natural vegetation by imitating natural or semi-natural streams. Treatment transformed the riparian structure and increased the diversity of micro-topography and vegetation. Furthermore, restoration recovered species composition, increased species diversity, and inhibited the establishment of exotic species. In particular, the Suip stream, which was left to its natural process for approximately 50 years, recovered its natural features almost completely through passive restoration. An urban stream, the Yangjae, and a rural stream, the Dongmoon, were restored partially by applying ecological principles. On the contrary, technological treatment applied to recover flood damage induced species composition far from the natural vegetation and decreased species diversity. Additionally, this treatment increased exotic species. The same results were found also in benthic invertebrate and fish fauna. The above-mentioned results reflect the importance of ecological considerations in river management.

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경남지역 논토양 미생물 특성과 글로말린 함량 상관관계 (The Relationship between Microbial Characteristics and Glomalin Concentrations in Paddy Soils of Gyeongnam Province)

  • 이영한;김민근;옥용식
    • 한국토양비료학회지
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    • 제45권5호
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    • pp.792-797
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    • 2012
  • 경남지역 논토양의 글로말린 함량과 미생물 특성과의 관계를 분석하기 위하여 2011년에 20개소를 선정하여 분석한 결과는 다음과 같다. 토양 글로말린 함량은 토양 유기물 함량 (r=0.595, p<0.01) 및 탈수소효소 활성 (r=0.663, p<0.01)과 정의상관 관계를 나타냈다. 또한, 글로말린 함량은 미생물 생체 탄소 함량 (r=0.710, p<0.001) 및 총 세균군집 (r=0.616, p<0.01)과 정의상관을 보였다. 그리고 글로말린 함량은 그람음성 세균의 군집 (r=0.561, p<0.05) 및 cy19:0/18:$1{\omega}7c$ (r=0.487, p<0.05)와 정의상관 관계를 나타냈다. 따라서 논토양에서 글로말린 함량은 지속가능한 친환경농업을 위해 토양 건강성의 지표로 활용할 수 있을 것으로 생각된다.

정수처리장내 급속모래 여과지의 이단복합여과시스템으로의 개량 (Improvement of Rapid Sand Filtration to Two Stage Dual Media Filtration System in Water Treatment Plant)

  • 우달식;황규원;김준언;황병기;조관형
    • 한국환경보건학회지
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    • 제37권2호
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    • pp.141-149
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    • 2011
  • This study aimed for developing a two stage dual media filtration system. It has a sand and activated carbon layer above the under-drain system, and a sand layer above the middle-drain system for pretreatment. When retrofitting an old sand filter bed or designing a new one, this technology can substitute the existing sand filter bed without requiring a new plant site. The removal rate of total particle is 93, and 3~7 ${\mu}m$ and 5~15 ${\mu}m$ particles are all 97%. These high removal efficiencies of each pollutant due to adsorption and biological oxidation in activated carbon filter layer. The best backwashing method of two stage dual media filtration system is ascertained by air injection, air + water injection and water injection sequence. In this study, a pilot plant of two stage and dual filtration system was operated for 4 months in water treatment plant. The stability of turbidity was maintained below 1 NTU. The TOC, THMFP and HAAFP were removed about 90% by two stage and dual media filtration system, which is almost 2 times higher than existing water treatment plant.

생리활성 펩타이드의 피부미용학적 특성 및 활용 (Characteristics and Applications of Bioactive Peptides in Skin Care)

  • 모상현;정대현;김형식;조문진;서효현;김성준
    • KSBB Journal
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    • 제26권6호
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    • pp.483-490
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    • 2011
  • Bioactive peptides (BAP) showed excellent cosmetic activity than bio-materials such as caffeic acid (CA), gallic acid (GA), and nicotinic acid (NA). Caffeoyl tripeptide-1 (CT-1) is a BAP that is stabilized with Gly-His-Lys (GHK) tripeptide and CA by using Fmoc solid phase peptide synthesis. Digalloyl tetrapeptide-19 (DT-19) is stabilized by combining Lys-Glu-Cys-Gly with GA and nicotinoyl tripeptide-1 (NT-1) is synthesized by GHK and NA. According to experiments, CT-1 has an excellent anti-oxidant function even with a very small amount of 10 ppm CT-1. DT-19's tyrosinase inhibition activity has the better effect of about 28.57% in 0.01% and 33.33% in 0.005% of concentration and about 7.89% in 0.001% concentration than vitamin-C. In addition, NT-1 is safer than the NA. Almost BAPs like pal-KTTKS, acetyl hexapeptide, and copper tripeptide-1 have the anti-wrinkle effect while DT-19 and NT-1 are applicable for potential BAPs focused on the whitening effect. The three kinds of BAPs like CT-1, DT-19, and NT-1 consisting of amino acids are safe to the skin, and have more excellent stability than bio-materials which are found to be unstable and cause skin irritation. Due to the high biological activity of BAP in the field of skin care, its utilization will increase constantly.

혹명나방저항성 GM 벼의 분자생물학적 특성 및 특이 마커를 이용한 검정 (Molecular biological characteristics and analysis using the specific markers of leaf folder-resistant GM rice)

  • 신공식;이시명;임선형;우희종;조현석;이경렬;이명철;권순종;서석철
    • Journal of Plant Biotechnology
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    • 제36권2호
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    • pp.115-123
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    • 2009
  • In recent years, several genetically modified (GM) crops have been developed worldwide through the recombinant DNA technology and commercialized by various agricultural biotechnological companies. Commercialization of GM crops will be required the assesment of risks associated with the release of GM crops. In advance of the commercial release of GM crops, developer should submit the several information on GM crops for approval. In this study, we carried out to provide the molecular data for the risk assessment of GM rice containing insect-resistant gene, modified Cry1Ac (CryIAc1). Through the molecular analysis with CryIAc1 induced GM rice, we confirmed the steady integration and expression of transgene, the transgene copy number, the adjacent region sequences of inserted gene into rice genome, and the transgene stability in progenies. For the qualitative PCR detection methods, specific primer pairs were designed on the basis of integration sequences, and construct- and event-specific detection markers were developed for leaf folder-resistant rice, Cr7-1 line. From these results, we demonstrated that the molecular data and the PCR detection methods of leaf folderresistant GM rice could be acceptable to conduct the biosafety and environment risk assessment.

Synthesis of Magnetic Sonophotocatalyst and its Enhanced Biodegradability of Organophosphate Pesticide

  • Lirong, Meng;Jianjun, Shi;Ming, Zhao;Jie, He
    • Bulletin of the Korean Chemical Society
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    • 제35권12호
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    • pp.3521-3526
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    • 2014
  • A magnetic sonophotocatalyst $Fe_3O_4@SiO_2@TiO_2$ is synthesized for the enhanced biodegradability of organophosphate pesticide. The as-prepared catalysts were characterized using different techniques, such as X-ray diffraction (XRD) and transmission electron microscopy (TEM). The radial sonophotocatalytic activity of $Fe_3O_4@SiO_2@TiO_2$ nanocomposite was investigated, in which commercial dichlorvos (DDVP) was chosen as an object. The degradation efficiency was evaluated in terms of chemical oxygen demand (COD) and enhancement of biodegradability. The effect of different factors, such as reaction time, pH, the added amount of catalyst on $COD_{Cr}$ removal efficiency were investigated. The average $COD_{Cr}$ removal efficiency reached 63.13% after 240 min in 12 L sonophotocatalytic reactor (catalyst $0.2gL^{-1}$, pH 7.3). The synergistic effect occurs in the combined sonolysis and photocatalysis which is proved by the significant improvement in $COD_{Cr}$ removal efficiency compared with that of solo photocatalysis. Under this experimental condition, the $BOD_5/COD_{Cr}$ ratio rose from 0.131 to 0.411, showing a remarkable improvement in biodegradability. These results showed that sonophotocatalysis may be applied as pre-treatment of pesticide wastewater, and then for biological treatment. The synthesized magnetic nanocomposite had good photocatalytic performance and stability, as when it was used for the fifth time, the $COD_{Cr}$ removal efficiency was still about 62.38%.