• Title/Summary/Keyword: biological process

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Transformation Characteristics of Chlorinated Aliphatic Hydrocarbon (CAH) Mixtures in a Two-Stage Column: 1st Chemical Column Packed with Zinc Natural Ore and 2nd Biological Column Stimulated with Propane-Oxidizing Microorganisms (아연 광석과 프로판산화 미생물을 이용한 이단 고정상 반응기에서의 염소계 지방족 탄화수소 혼합물 분해 특성)

  • Son, Bong-han;Kim, Nam-hee;Hong, Kwang-pyo;Yun, Jun-ki;Lee, Chae-young;Kwon, Soo-youl;Kim, Young
    • Journal of Korean Society on Water Environment
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    • v.23 no.5
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    • pp.723-730
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    • 2007
  • This study was conducted to develop a combined method for remediating a Chlorinated Aliphatic Hydrocarbons (CAHs) mixtures-contaminated aquifer. The process is consist of two processes. A chemical process (1st) using natural zinc ores for reducing higher concentrations of CAH mixtures to the level at which biological process is feasible; and A biological process (2nd) using aerobic cometabolism for treating lower concentration of CAH mixtures (less than 1 mg/L). Natural zinc ore showed relatively high transformation capacity, average dehalogenation percentage, and the best economic efficiency in previously our study. To evaluate the feasibility of the process, we operated two columns in series (that is, chemical and biological columns). In the first column filled with natural zinc ore and sand, CAH mixtures were effectively transformed with more than 95% efficiency, the efficiency depends on the Empty Bed Contact Time (EBCT) and the mass of zinc ore packed. Scanning Electron Microscope (SEM), X-Ray Diffraction (XRD) analysis were performed to make sure whether natural zinc ore played an key role in the dechlorination of the CAH mixtures. The characteristics of zinc metal surface changed after exposure to CAHs due to oxidation of $Zn^0$ to $Zn^{2+}$. In the biological column injecting propane, DO and effluent of the chemical column, only 1,1,1-TCA was cometabolically transformed. Consequently, the combined process would be effective to remediate an aquifer contaminated with high concentrations of CAH mixtures.

Validation Process of HPLC Assay Methods of Drugs in Biological Samples (생체시료내 약물의 HPLC 분석법에 대한 유효성 검토방법)

  • Chi, Sang-Cheol;Jun, H.-Won
    • Journal of Pharmaceutical Investigation
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    • v.21 no.3
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    • pp.179-188
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    • 1991
  • An HPLC assay method of a drug to be applied to the pharmacokinetic studies of the drug should be completely validated. The validation process for an HPLC assay method in a biological sample was discussed using the data obtained from the development of HPLC method for the simultaneous quantitation of verapamil and norverapamil in human serum. The validation criteria included were specificity, linearity, accuracy, precision, sensitivity, recovery, drug stability, and ruggedness of an assay method.

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CONVERGENCE OF A GENERALIZED BELIEF PROPAGATION ALGORITHM FOR BIOLOGICAL NETWORKS

  • CHOO, SANG-MOK;KIM, YOUNG-HEE
    • Journal of applied mathematics & informatics
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    • v.40 no.3_4
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    • pp.515-530
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    • 2022
  • A factor graph and belief propagation can be used for finding stochastic values of link weights in biological networks. However it is not easy to follow the process of use and so we presented the process with a toy network of three nodes in our prior work. We extend this work more generally and present numerical example for a network of 100 nodes.

Wastewater Treatment by Microorganism (미생물에 의한 발효처리)

  • ;Kunisuke Ichikawa
    • Microbiology and Biotechnology Letters
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    • v.8 no.2
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    • pp.135-142
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    • 1980
  • The process of biological treatment of organic wastewater is principally associated with those of self-purification in the natural water environment. The treatment system has e intensive function of stabilizing wastewater more effectively than in natural water, which is like natural water concentrated in a small space. Biological treatment of wastewater involves activated sludge and various modified process, trickling filter, rotating disk, oxidation ditch, etc. for aerobic decomposition and anaerobic processes such as anaerobic decomposition and methane fermentation. The basic characteristic of these processes is the use of mixed culture for the conversion of pollutants. This review forcuses on the various kinds of microorganisms related to each treatment processes. Kinetic analysis of the activated sludge process is discussed in order to understand the basis of control and maintenance of the biological treatment process.

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Pathophysiology of Oral Mucositis induced by Anticancer Therapy (항암치료 후 발생하는 구강 점막염의 병태생리)

  • Yoon, Jung-Hoon;Choj, Jong-Hoon
    • Journal of Oral Medicine and Pain
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    • v.25 no.4
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    • pp.365-369
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    • 2000
  • Oral mucositis or stomatitis produced by stomatotoxic chemotherapy and/or radiation therapy are painful, restrict oral intake and, importantly, act as sites of secondary infection and potals of entry for the endogenous oral microflora often leading to bacteremias or sepsis. A number of clinical observations and studies of animal model suggests a pathophysiological complexity in the development of mucositis. The condition appears to represent a sequential interaction of the oral mucosal cells and tissues, pro-inflammatory cytokines, and local environmental factors in the mouth. This article discussed and reviewed biological process of the mucositis and, the role of cytokines as initiators and amplifiers of the process. The recognition that the pathophysiology of mucositis is a multifactorial process has presented opportunities for intervention based upon biological attenuation.

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Development of Biological Filtration Process for Effective Nitrogen Removal and its Control strategies in Tertiary Treatment of Sewage (생물막 여과반응기를 이용한 고도질소 제거를 위한 운전제어법 개발)

  • Jeong, Jin-Woo;Kim, Sung-Won;Tsuno, Hiroshi
    • Journal of Korean Society on Water Environment
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    • v.22 no.2
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    • pp.230-237
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    • 2006
  • The operational parameters and control strategies of a tertiary wastewater treatment process a biological filtration system were investigated. The biological filtration system consisted of a nitrification filter (Fiter 1) and a polishing filter with anoxic and aerobic parts (Filter 2). SS, T-C-BOD, and T-N in effluent were kept stable at less than 3, 5 mg/L, and 5 mgN/L, respectively, under a HRT in Filter (filter-bed) of 0.37~2.3 h. T-N at the outlet of Filter 2 were about 1~5 mgN/L under the condition of LV of 50~202 m/d. Methanol addition was controlled based on the COD/N ratio or McCarty's equation. Constant COD/N ratio control results in excess addition under large diurnal fluctuation of $NOx^--N$, and McCarty's equation can be used to add appropriate amount of methanol. Control of methanol addition by on-line nitrate measurement, control of aeration by on-line DO measurement, and control of backwashing by head loss measurement are successfully operated. These results proved that this process prove the easy-maintenance and cost-effectively treatment is attainable.

Signaling Molecules at the Conceptus-Uterine Interface during Early Pregnancy in Pigs

  • Seo, Heewon;Choi, Yohan;Shim, Jangsoo;Kim, Mingoo;Ka, Hakhyun
    • Journal of Embryo Transfer
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    • v.27 no.4
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    • pp.211-221
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    • 2012
  • The process of embryo implantation requires physical contact and physiological communication between the conceptus trophectoderm and the maternal uterine endometrium. During the peri-implantation period in pigs, the conceptus undergoes significant morphological changes and secretes estrogens, the signal for maternal recognition of pregnancy. Estrogens secreted from the conceptus act on uterine epithelia to redirect $PGF_2{\alpha}$, luteolysin, secretion from the uterine vasculature to the uterine lumen to prevent luteolysis as well as to induce expression of endometrial genes that support implantation and conceptus development. In addition, conceptuses secrete cytokines, interferons, growth factors, and proteases, and in response to these signals, the uterine endometrium produces hormones, protease inhibitors, growth factors, transport proteins, adhesion molecules, lipid molecules, and calcium regulatory molecules. Coordinated interactions of these factors derived from the conceptus and the uterus play important roles in the process of implantation in pigs. To better understand mechanism of implantation process in pigs, this review provides information on signaling molecules at the conceptus-uterine interface during early pregnancy, including recently reported data reported.

Plasma Density Measurement of Linear Atmospheric Pressure DBD Source Using Impedance Variation Method (임피던스 변화를 이용한 선형 대기압 DBD 플라즈마 밀도 측정)

  • Shin, Gi Won;Lee, Hwan Hee;Kwon, Hee Tae;Kim, Woo Jae;Seo, Young Chul;Kwon, Gi-Chung
    • Journal of the Semiconductor & Display Technology
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    • v.17 no.2
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    • pp.16-19
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    • 2018
  • The development speed of semiconductor and display device manufacturing technology is growing faster than the development speed of process equipment. So, there is a growing need for process diagnostic technology that can measure process conditions in real time and directly. In this study, a plasma diagnosis was carried out using impedance variation due to the plasma discharge. Variation of the measurement impedance appears as a voltage change at the reference impedance, and the plasma density is calculated using this. The above experiment was conducted by integrating the plasma diagnosis system and the linear atmospheric pressure DBD plasma source. It was confirmed that plasma density varies depending on various parameters (gas flow rate, $Ar/O_2$ mixture ratio, Input power).

Analysis of Ingredients and biological activities confirm Process for Personalized Diet Offering Service: Basic ingredients Analysis and biological Activities of Grifola frondosa

  • Hong, Seok Chan;Hwang, You Jin;Kang, Un Gu
    • Journal of the Korea Society of Computer and Information
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    • v.24 no.8
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    • pp.113-121
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    • 2019
  • The personalized meal service is being developed to prevent and alleviate illnesses according to the individual's health condition. However, the current meal does not provide a fully customized service to individuals and a diet that meets the consumer's information needs. The cause is the lack of information on the ingredients and the difficulty of comparative analysis between the materials. Therefore, in this study, we propose basic analysis process for basic information acquisition and database construction for food composition before providing personalized food. In this study, we investigated the content of carbohydrate, reducing sugar and protein as basic components of Grifola frondosa and investigate the content of polyphenol as a biological active ingredients. Respectively. Studies on the hypoglycemic effect of the diabetic rat model have been carried out in relation to the prevention of diseases. Based on the results of this study, it is also possible to obtain information on the basic ingredients of the food and to analyze the information on the content and activity of the biological active ingredients. Using animal models, information on disease prevention and mitigation was also available. The process introduced in this study is applied to various food materials, accumulating data, and utilizing Database, this results will be an excellent tool for providing more efficient service by providing a proper dietary composition for consumers.