• The Korean Journal of Pain
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• 제9권2호
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• pp.336-339
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• 1996

Stellate ganglion block which usually practiced in pain clinics may combined with hemodynamic changes because it blocks sympathetic nerve chains. We measured the hemodynamic changes with NCCOM3-$R7^{(R)}$ (BOMED, U.S.A.) which applicated bioimpedance method in twenty-two patients. Mean arterial pressure, heart rate, cardiac output, ejection fraction and left ventricle end diastolic volume (LEDV) were measured before stellate ganglion block (control), 1, 3, 5, 10 and 20 minutes after stellate ganglion block with 8 ml of 0.25% bupivacaine. The results were as follows: Mean arterial pressure decreased significantly (p<0.05) in 10, 20 minutes after stellate ganglion block comparing to control, but not clinically significant. Heart rate, cardiac output, ejection fraction and LVEDV showed no significant change compared to control value. These results showed that stellate ganglion block is a safe technique without significant hemodynamic changes.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2005년도 학술대회 논문집 정보 및 제어부문
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• pp.75-77
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• 2005

When measuring impedance of electronic component and so on, even the small size can reject the interference to shielding object. But, the interference through human body is grown when measuring bioimpedance without establishing shield specially. Consequently, when measuring bioimpedance in this paper, it proposed impedance measurement method to take advantage of spread spectrum technology, so that can reject the interference without establishing shield specially. Spread spectrum impedance measurement method to propose in this paper can reject the interference signal that occurring from medical instruments in the human body, the interference signal that is flowed in from surrounding environment when measuring impedance. It improved SJR(signal to jamming ratio) about 22dB than conventional method that actually realize and experiment spread spectrum impedance measurement method.

• 전기학회논문지
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• 제65권1호
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• pp.194-199
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• 2016

EMG has specific information which is related to movements according to the activities of muscles. Therefore, users can intuitively control a prosthesis. For this reason, biosignals are very useful and convenient in this kind of application. Bioimpednace also provides specific information about movements like EMG. In this study, we used both EMG and bioimpedance to classify the typical hand gestures such as hand open, hand close, no motion (rest), supination, and pronation. Nine able-bodied subjects and one amputee were used as experimental data set. The accuracy was $98{\pm}1.9%$ when 2 bio-impedance and 8 EMG channels were used together for normal subjects. The number of EMG channels affected the accuracy, but it was stable when more than 5 channels were used. For the amputee, the accuracy is higher when we use both of them than when using only EMG. Therefore, accurate and stable hand motion estimation is possible by adding bioimepedance which shows structural information and EMG together.

• 동의생리병리학회지
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• 제36권3호
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• pp.94-99
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• 2022

The discovery of biomarkers related to pattern identification (PI), the core diagnostic theory of Korean medicine (KM), is one of the methods that can provide objective and reliable evidence by applying PI to clinical practice. In this study, 40 diabetic patients and 41 healthy control subjects recruited from the Korean medicine clinic were examined to determine the human electrical response related to the deficiency pattern, a representative pattern of diabetes. Qi-Blood-Yin-Yang deficiency pattern scores, which are representative deficiency patterns for diabetes mellitus, were obtained through a questionnaire with verified reliability and validity, and the human electrical response was measured non-invasively using a bioimpedance meter. In ANCOVA analysis using gender as a covariate, the 5 kHz frequency resistance and 5-250 kHz frequency reactance were significantly lower in the diabetic group than in non-diabetic control group. In addition, the multiple regression analysis showed a positive correlation (R2=0.11~0.19) between the Yang deficiency pattern score and resistance value for the diabetic group; the correlation was higher at higher frequencies of 50kHz (R2=0.18) and 250kHz (R2=0.19) compared to 5kHz(R2=0.11). In contrast, there was no such significant association in the control group. It implies that bioimpedance resistance measured at finite frequencies may be useful in predicting Yang deficiency, which is closely related to diabetic complications by reflecting the decrease in body water content and metabolism. In the future, large-scale planned clinical studies will be needed to identify biomarkers associated with different types of PI in diabetes.

• 센서학회지
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• 제20권2호
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• pp.71-76
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• 2011

To characterize the relationship between the stage of hepatic fibrosis and bioimpedance, several electric parameters were estimated in rats with $CCl_4$-induced liver fibrosis. Thirty three Sprague-Dawley rats were intraperitoneally injected with a $CCl_4$-mineral oil mixture (1:1, 0.2 mL/100 g) twice a week for 8 weeks. The resistance(R), reactance(X), impedance(Z), and dissipation factor(D) between 1 kHz and 100 kHz were then evaluated in the livers of the rats under pentobarbital anesthesia using an HP4294A Impedance Analyzer. The rats were killed 2, 4, 6, and 8 weeks later, and their livers were classified in accordance with Ishak's scoring system. R, X, and Z changed in accordance with the progression of hepatic fibrosis and the changes were greater at lower frequencies than at higher frequencies. In comparison, the D spectrum was biphasic; D increased initially then decreased with increasing frequency. All of the parameters(R, X, Z, and D) changed in accordance with the stage of fibrosis in the livers, but D changed specifically with the progression of fibrosis. These results indicate that hepatic fibrosis may be evaluated by determining the changes in D.

• 대한전자공학회:학술대회논문집
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• 대한전자공학회 2003년도 하계종합학술대회 논문집 V
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• pp.2753-2756
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• 2003

A convenient, tunable loop-gain negative impedance circuit that increases input impedance of a front-end in a bioimpedance measurement has been proposed. Since the proposed circuit comprises wide-band operational amplifiers, selecting operational amplifiers is easy, while an operational amplifier of proper bandwidth should be chosen to use conventional circuit. Also, since loop-gain can be controlled by a feedback resistor connected serially with a feedback capacitor, loop-gain is tunable with a potentiometer. The input impedance of the proposed circuit is two times larger than that of the conventional circuit. Furthermore, closed loop phase response of the proposed circuit is better than that of the conventional circuit or without a negative capacitance circuit. The implemeted, proposed circuit showed stable operation and a zero input capacitance.

• 대한전기학회논문지:시스템및제어부문D
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• 제55권4호
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• pp.195-197
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• 2006

When we measure electrical impedance of a small object, such as an electronic component, external interference or jamming signal can be rejected by shielding the object. However, when we measure impedance of a large object, such as a human body, shielding is not easy and severe error due to the external interference could be introduced. In this paper, spread spectrum technique applicable to bioimpedance measurements for rejecting external interference without shielding is introduced. The improvement in signal-to-jamming ratio by the spread spectrum technique was experimentally confirmed.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2003년도 학술회의 논문집 정보 및 제어부문 A
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• pp.179-182
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• 2003

A simulation on bootstrapping circuit has been performed by modelling a coaxial cable as a transmission line. It is shown that the bootstrapping circuit could be unstable due to the transmission line effect though an ideal amplifier is used. While the conventional bootstrapping circuit does not cancel the input capacitance of the input buffer, a new bootstrapping circuit that cancels input capacitance of the input buffer has been proposed. The proposed bootstrapping circuit consists of the input buffer of which gam is larger than 1 and a feedback resistor to control the loop gain. The proposed bootstrapping circuit has higher input impedance than that of the conventional circuit.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2003년도 학술회의 논문집 정보 및 제어부문 B
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• pp.940-942
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• 2003

This paper describes the possibility of analyzing gait pattern from the variation of the lower leg electrical impedance. This impedance is measured by the four-electrode method. Two current electrodes are applied to the thigh and foot, and two potential electrodes are applied to the lateral aspect, medial aspect, and posterior position of lower leg. We found the optimal electrode position for knee and ankle joint movements based on high correlation coefficient, least interference, and maximum magnitude of impedance change. From such features of the lower leg impedance, it has been made clear that different movement patterns exhibit different impedance patterns and impedance level.

• 대한의용생체공학회:의공학회지
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• 제22권6호
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• pp.503-510
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• 2001

인체의 각 조직은 서로 다른 저항률(resistivity)을 가지고 있고. 심장의 박동이나 호흡과 같은 생리현상은 해당 생체조직의 임피던스를 변화시킨다. 본 논문에서는 인체 내부에 존재하는 비정상 조직의 크기와 위치를 검출하기 위한 32-채널 생체 임피던스 측정 시스템에 대하여 기술한다. 이러한 기술은 유방암 조직의 경우와 같이 배경 조직과는 저항률이 다른 비정상 조직을 검출하는 경우에 응용할 수 있을 것으로 기대한다. 32-채널 생체 임피던스 측정 시스템을 위하여 32개의 복합형 전극과 32 채널의 정전류원을 사용하였다. 임피던스의 측정을 위해 50kHz의 정현파 전류를 주입하고. 유기되는 전압을 가변 이득 협대역 계측용 증폭기로 측정하고, 그 크기를 위상감응복조기로 검출하였다. 검출된 임피던스 신호는 A/D 변환하여 PC에 입력하였다. 전해질 팬텀을 이용한 실험에서 전체 시스템의 정확도는 2.42%이며, 직경 270mm인 팬텀 내부에 존재하는 직경 8mm 이상인 물체의 크기와 위치를 검출할 수 있었다. 본 연구의 결과를 기초로 다채널 생체 임피던스 측정 시스템의 정확도를 개선하여. 직경 lmm 이내의 물체를 검출하는 것이 향후의 연구 목표이다 이러한 정확도를 가지는 생체 임피던스 계측 시스템을 개발하면. 인체 내부의 임피던스 분포를 측정하는 EIT(electrical impedance tomography) 시스템과, 최근에 연구되고 있는 자기공명 임피던스 단층촬영(MREIT, magnetic resonance electrical impedance tomography)에도 응용이 가능할 것이다.