• Korean Journal of Pharmacognosy
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• v.34 no.1 s.132
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• pp.40-44
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• 2003

Antler has been used as one of the important traditional oriental medicines for many years. It contains many biochemical components including lipids, peptides, carbohydrates, and inorganic substances. The various biological activities of antler are being considered owing to such biochemical components. The purpose of this research is to compare the biochemical components of antlers after treatment of three different kinds of fodder. They are mulberry (group A), Lycii Fructus (group B) and the complex of herbs (group C). The chemical composition of each antler was determined in three sections (top, middle, and bottom) and compared with those of the control. The contents of sialic acid, uronic acid and glycosaminoglycans increased in the top antlers of the group B. Total lipids content increased in the top antlers of all groups (A, B, and C). The concentration of inorganic ions (Ca, Mg, and P) decreased in all groups. Fattyacid composition was also analyzed by GC-MS and expressed as percentage of total fatty acid concentration. The content of palmitic acid decreased in all groups. The content of 2-hydrox-yhexadecanoic acid, which has not been reported in aster, increased in the top antlers of all groups. These results suggest that the treatment of special fodder may affect the composition of the biochemical components of antlers.

• Proceedings of the Ginseng society Conference
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• 1990.06a
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• pp.123-131
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• 1990

• 한국생물공학회:학술대회논문집
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• 2005.04a
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• pp.221-221
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• 2005

• 한국생물공학회:학술대회논문집
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• 2005.10a
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• pp.401-401
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• 2005

• Journal of Community Nutrition
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• v.6 no.3
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• pp.155-163
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• 2004

In our country, cardiovascular disease (CVD) and Coronary heart diseases (CHD) are the leading causes of death. It is well known that CHD is multifactorial, involving environmental factors such as diet, level of exercise and cigarette smoking, and inherited factors. According to the statistical data in 2003, the cause of death with the highest mortality was including hypertension, ischemic heart disease and atherosclerosis, which accounted for $24.7\%$ of total mortality. In spite of, there have been few study reports on the change of biochemical markers and mechanisms concerned. The development of biochemical markers is required for an early diagnosis and treatment of cardiovascular diseases that are related with dietary habits of Korean people enjoying mixtures of traditional dietary style and westernized food-styles. Therefore, the most efficient cost-saving biochemical marker was established in this study, through analysis of biochemical markers related with dietary habits which are susceptibly being changed in association to cardiovascular diseases from the pre-disease phase, and through reanalysis and assessment of early diagnosis of and preventive effects of diagnosis of cardiovascular diseases by demographical character including sex, age, and socioeconomic level with use of biochemical markers that are identified and selected among the parameters in consideration of the effectiveness and appropriateness of early diagnosis of diseases. The appropriateness of biochemical markers was reviewed by professionals (medical, pharmaceutical area and food/ nutrition area) and CRP(C-Reactive Protein) and was identified to be possible in Korea. It is thought that these biochemical markers may be used as the basic data for early diagnosis and prevention of cardiovascular diseases (CVD) which may be used for Korean people.

• Journal of Ginseng Research
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• v.17 no.2
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• pp.131-134
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• 1993

Panaxadiol (PD) from Korean red ginseng C.A. Meyer did not control the concentration of cytosolic free $Ca^{2+}$ influxes by thrombin (5 $\mu$/ml). However, PD strongly inhibited the synthesis of thromboxane. $A_2$ (TX$A_2$) in the aggregation of human platelets induced by thrombin (5 $\mu$/ml). These rexults suggest that PD blocks the any Pathway transforming to TX$A_2$ from arachidonic acid (AA) which release out of plasma membrane phospholipids by $Ca^{2+}$-dependent phospholipase C or phospholipase $A_2$. It may be also concluded that PD has the antiplatelet function by inhibiting the synthesis of TX$A_2$, which known to be the potent stimulator of the aggregation of human platelet.

• Clinical and Experimental Pediatrics
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• v.61 no.10
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• pp.332-337
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• 2018

Purpose: Bell's palsy is characterized by sudden onset of unilateral facial weakness. The use of corticosteroids for childhood Bell's palsy is controversial. This study aimed to identify clinical characteristics, etiology, and laboratory findings in childhood Bell's palsy, and to evaluate the efficacy of corticosteroid treatment. Methods: We conducted a retrospective analysis of children under 19 years of age treated for Bell's palsy between January 2009 and June 2017, and followed up for over 1 month. Clinical characteristics, neuroimaging data, laboratory findings, treatments, and outcomes were reviewed. Patients with Bell's palsy were divided into groups with (group 1) and without (group 2) corticosteroid treatment. Differences in onset age, sex, laterality, infection and vaccination history, degree of facial nerve palsy, and prognosis after treatment between the groups were analyzed. Results: One hundred patients were included. Mean age at presentation was $7.4{\pm}5.62years$. A total of 73 patients (73%) received corticosteroids with or without intravenous antiviral agents, and 27 (27%) received only supportive treatment. There was no significant difference in the severity, laboratory findings, or neuroimaging findings between the groups. Significant improvement was observed in 68 (93.2%) and 26 patients (96.3%) in groups 1 and 2, respectively; this rate was not significantly different between the groups (P=0.48). Conclusion: Childhood Bell's palsy showed good prognosis with or without corticosteroid treatment; there was no difference in prognosis between treated and untreated groups. Steroid therapy in childhood Bell's palsy may not significantly improve outcomes.

• Natural Product Sciences
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• v.16 no.4
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• pp.228-232
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• 2010

Bioactivity-guided fractionation using on-line HPLC biochemical detection system on $CHCl_3$-soluble fraction of Lycoris radiata led to the isolation of deoxylycorenine (1), O-demethylhomolycorine (2), galanthamine (3), lycoramine (4), mixture of $6{\alpha}$-and $6{\beta}$-haemanthidine (5), and lycorine (6), identified by spectroscopic data and physicochemical property. Among the isolated compounds, 1, 3 and 6 showed acetylcholinesterase inhibitiory activities with $IC_{50}$ values of 18.0, 12.0 and $16.6\;{\mu}M$, respectively, in in vitro colorimetric microplate assay.

• International Journal of Industrial Entomology and Biomaterials
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• v.18 no.2
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• pp.135-138
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• 2009

Studies on the effect of different secondary nutrients in different doses on the leaf yield and biochemical constituents of Terminalia tomentosa revealed that secondary nutrients have promotary effect in increasing the leaf yield and foliar constituents of Terminalia tomentosa. Among all the treatments under study, foliar application of magnesium sulphate (2g/plant, w/v) is the best in respect of leaf yield and biochemical constituents of T. tomentosa. This treatment gave 29.15% increase in leaf yield over control. Chemoassay results further confirmed significant improvement in biochemical constituents. Except crude fibre, moisture, minerals, crude protein and total carbohydrate increased significantly over control.

• Journal of Ginseng Research
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• v.17 no.2
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• pp.135-138
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• 1993

Aqueous fractions from Korean red ginseng inhibited the phosphorylations of 40 KD and 20 KD polypeptides which were induced by phorbol-12-myristate-13-acetate (100 nM) in human platelets. Much more carbohydrates were contained in the aqueous fractions than proteins. An aqueous fraction extracted with methanol, mainly, consists of glycoproteins, molecular weights of which were below 18 KD. We may infer that the aqueous fraction from Korean red ginseng do antitumorous and antiplatelet functions.