The Isolation of Acetylcholinesterase Inhibitory Constituents from Lycoris radiata using On-line HPLC-biochemical Detection System
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Yang, Hee-Jung
(College of Pharmacy and Research Institute of Pharmaceutical Science, Seoul National University)
Yoon, Kee-Dong (College of Pharmacy and Research Institute of Pharmaceutical Science, Seoul National University) Chin, Young-Won (College of Pharmacy and Research Institute of Pharmaceutical Science, Seoul National University) Kim, Young-Choong (College of Pharmacy and Research Institute of Pharmaceutical Science, Seoul National University) Kim, Jin-Woong (College of Pharmacy and Research Institute of Pharmaceutical Science, Seoul National University) |
1 | Miyasaka, K., Hiramatsu, Y., Takezaki, T., Pharmacological studies of lycorenine, an alkaloid of Lycoris radiata Herb.: Vasodepressor mechanism in rats. Jpn J Pharmacol 29, 605-622 (1979). DOI |
2 | Pabuccuoglu, V., Richomme, P., Gozler, T., Kivcak, B., Freyer, A. J., Shamma, M., Four New Crinine-Type Alkaloids from Sternbergia Species. J Nat Prod 52, 785-791 (1989). DOI |
3 | Park, J. H., Sung, S. H., Haeksim-Yakyongsikmul. Sin-Il Books: Seoul pp 2-3 (2007). |
4 | Son, M., Kim, A., Lee, J., Park, C. H., Heo, J. C., Lee, H. J., Lee, S. H., Ethanol extract of Lycoris radiata induces cell death in B16F10 melanoma via p38-mediated AP-1 activation. Oncol Rep 24, 473-478 (2010). |
5 | Terry, A. V., Jr., Buccafusco, J. J., The cholinergic hypothesis of age and Alzheimer's disease-related cognitive deficits: recent challenges and their implications for novel drug development. J Pharmacol Exp Ther 306, 821-827 (2003). DOI ScienceOn |
6 | Kihara, M., K., K., L., X., Kobayashi, S., Alkaloidal Constituents of the Flowers of Lycoris radiata Herb. (Amaryllidaceae). Chem. Pharm. Bull. 39, 1849-1853 (1991). DOI |
7 | Kobayashi, S., Yuasa, K., Imakura, Y., Kihara, M., Shingu, T., Isolation of O-Demethyllycoramine from Bulbs of Lycoris radiata HERB. Chem. Pharm. Bull. 28, 3433-3436 (1980). DOI |
8 | Krall, W. J., Sramek, J. J., Cutler, N. R., Cholinesterase inhibitors: a therapeutic strategy for Alzheimer disease. Ann Pharmacother 33, 441-450 (1999). DOI ScienceOn |
9 | Li, S. Y., Chen, C., Zhang, H. Q., Guo, H. Y., Wang, H., Wang, L., Zhang, X., Hua, S. N., Yu, J., Xiao, P. G., Li, R. S., Tan, X., Identification of natural compounds with antiviral activities against SARS-associated coronavirus. Antiviral Res 67, 18-23 (2005). DOI ScienceOn |
10 | Likhitwitayawuid, K., Angerhofer, C. K., Chai, H. B., Pezzuto, J. M., Cordell, G. A., Traditional Medicinal-Plants of Thailand .22. Cytotoxic and Antimalarial Alkaloids from the Bulbs of Crinum-Amabile. J Nat Prod 56, 1331-1338 (1993). DOI ScienceOn |
11 | Codina, C., Bastida, J., Viladomat, F., Fernandez, J. M., Bergonon, S., Rubiralta, M., Quirion, J. C., Alkaloids from Narcissus-Munozii- Garmendiae. Phytochemistry 32, 1354-1356 (1993). DOI ScienceOn |
12 | Ingkaninan, K., de Best, C. M., van der Heijden, R., Hofte, A. J., Karabatak, B., Irth, H., Tjaden, U. R., van der Greef, J., Verpoorte, R., High-performance liquid chromatography with on-line coupled UV, mass spectrometric and biochemical detection for identification of acetylcholinesterase inhibitors from natural products. J Chromatogr A 872, 61-73 (2000). DOI ScienceOn |
13 | Jegorov, A., Buchta, M., Sedmera, P., Kuzma, M., Havlicek, V., Accurate product ion mass spectra of galanthamine derivatives. J Mass Spectrom 41, 544-548 (2006). DOI ScienceOn |
14 | Bores, G. M., Huger, F. P., Petko, W., Mutlib, A. E., Camacho, F., Rush, D. K., Selk, D. E., Wolf, V., Kosley, R. W., Jr., Davis, L., Vargas, H. M., Pharmacological evaluation of novel Alzheimer's disease therapeutics: acetylcholinesterase inhibitors related to galanthamine. J Pharmacol Exp Ther 277, 728-738 (1996). |
15 | Kiely, J. S., Moos, W. H., Pavia, M. R., Schwarz, R. D., Woodard, G. L., A silica gel plate-based qualitative assay for acetylcholinesterase activity: a mass method to screen for potential inhibitors. Anal Biochem 196, 439-442 (1991). DOI ScienceOn |
16 | Blennow, K., de Leon, M. J., Zetterberg, H., Alzheimer's disease. Lancet 368, 387-403 (2006). DOI ScienceOn |
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