• 보건의료산업학회지
• /
• 제5권2호
• /
• pp.1-14
• /
• 2011

The purpose of this study was analyzed the factors of influencing toward attitude to death with dignity to hospice volunteers. The data was collected for 21 days from 14 March to 3 April 2010. Among a total of 220 cases of the questionaries, only 195 cases were used. To data were analyzed by factor analysis, independent t-test, one-way anova and logistic regression using PASW statistics 18.0. The results were as follows; The attitudes towards death with dignity according to general characteristics was high in those with will to agreed to the passive euthanasia than those opposite to the attitude factors, namely, acceptive, the right to decide, negative, and dereliction of duty attitude factors. Significant variables for effects of death with dignity were gender, acceptive attitude factor and dereliction of duty attitude factors. Given that main provider of human organs is the brain-dead and we don't have enough organ donation, death with dignity should be linked with activating policy of organ donation, while solving donation shortage problem. This way, constructing social implementation and sharing consciousness on organ donation, would be diluting the bio-ethic controversies.

• 대한한의학원전학회지
• /
• 제21권1호
• /
• pp.153-162
• /
• 2008

Three Eum and Three Yang[三陰三陽] is a way of studying the changing of nature from a Eum(陰) and Yang(陽) point of view, Juhakhae(周學海) divides this into two dimensions. The first is the concept of dividing the exterior part of the body excluding the organ into 6 divisions as Eumyang(陰陽) of front and rear characteristic. The second is the concept of dividing the systematic bio-activity of the central organ into another 6 dimensions. The former concept is illustrated in the body as a certain meridian controlling a certain field of the body, while the latter is presented as a certain organ performing an activity of Gi(氣). Three Eum and Three Yang[三陰三陽] is not based on fixed substances. but it is a thought process model of observing the structural-functional changes of the body in disease state. Therefore, by understanding Three Eum and Three Yang[三陰三陽] of field and activity of Gi(氣) respectively and comprehensively putting these into practice, we will be able to approach the essence of the disease state in a more precise manner.

• 한국가금학회지
• /
• 제33권1호
• /
• pp.33-39
• /
• 2006

본 연구는 브로일러 사료에 일라이트와 은을 이온 결합시킨 $bio-silverlite^{(R)}$의 첨가가 육계의 육성 성적, 장기 변화 및 장내 미생물 성상에 미치는 영향을 검토하고자 실시하였다. 처리구는 negative control과 항생제 첨가구에 속하는 positive control, 사료에 0.5(S 0.5%) 및 1.5%(S 1.5%)를 첨가구인 4처리구 5반복으로 반복당 10수씩 총 200수로 시험하였다. 증체량은 항생제 첨가구, S 0.5%구 및 S 1.5%구가 대조구에 비하여 높았으며, 사료 효율은 $bio-silverlite^{(R)}$ 첨가 수준이 높을수록 우수하게 나타났다(p<0.05). 소장 길이는 +C구가 -C나 $bio-silverlite^{(R)}$ 처리구(S 0.5% 구와 S 1.5% 구)에 비하여 높았으나(p<0.05), 소장 무게는 $bio-silverlite^{(R)}$ 첨가 수준이 높을수록 높게 나타났다(p<0.05). 근위 중량은 $bio-silverlite^{(R)}$ 첨가구가 -C구와+C구에 비하여 낮았으며(p<0.05), 맹장 무게는 $bio-silverlite^{(R)}$ 처리구가 높은 경향을 나타냈다. Villi의 길이는 S 1.5%구가 3주와 6주 후에도 -C구 및 +C구에 비하여 길었다. TBC와 CBC는 주령 및 사료 첨가제의 첨가 형태에 따른 변화가 거의 없는 것으로 나타났다. 반면 LAB는 negative 대조구인 -C 구에 비하여 +C 구 및 S 0.5% 및 S 1.5% 처리구에서 높은 경향을 나타냈다.

• Reproductive and Developmental Biology
• /
• 제33권4호
• /
• pp.249-255
• /
• 2009

The miniature pig is considered to be a better organ donor breed for xenotransplantation than other pig breeds because the size of the organs of the miniature pig is similar to that of humans. In this study, we aimed at identifying differentially expressed genes in the miniature pig ovary during pregnancy. For this, we used the miniature pig ovary model, annealing control primer-based reverse transcription polymerase chain reaction (PCR), quantitative real-time PCR (qRT-PCR), and northern blotting analysis. We identified 13 genes showing differential expression on the based of pregnancy status and validated 8 genes using qRT-PCR. We also sequenced the full-length cDNA of ephrin receptor A4 (EphA4), which had a significant difference in expression level, and validated it by northern blotting. These genes may provide a better understanding of the cellular and molecular mechanisms during pregnancy in miniature pig ovary.

• 한국환경과학회지
• /
• 제27권11호
• /
• pp.999-1005
• /
• 2018

The purpose of this study was to probe the influences of krill (Euphausia superba) meal with NaF oral administration on a dose-effect relationship between fluoride levels of krill meal and serum enzyme activity such as alkaline phosphatase (ALP), aspartate aminotransferase (AST), alanine aminotransferase (ALT), and lactate dehydrogenase (LDH) in rats fed experimental diets for 5 weeks. There were no significant decreases in the activities of ALP, AST, ALT, and LDH in sera among krill meal diet groups (KF10, KF20, KF30). However, these groups were significantly (p<0.05) lower enzyme activities than normal diet (ND) plus NaF 10 mg group (NF). The fluoride levels of serum and organ tissues (liver, brain, heart, lung, kidney) in NaF 10 mg groups (NF, KF10, KF20, KF30) were significantly increased by adding krill meal in comparison with normal diet group. The results indicate that a difficult to found toxicity to the tissues from krill meal diet groups.

• 대한방사선기술학회지:방사선기술과학
• /
• 제31권1호
• /
• pp.41-47
• /
• 2008

한국 성인 남성 표준인(Korean Reference Adult Male)의 기초 자료를 이용하여 수학적 모의 피폭체(Mathematical Phantom)를 제작하였다. 또한 이를 이용하여 방사성옥소($^{131}I$)의 각 장기별 S-value를 산출 하였다. 산출된 S-value는 기존 ICRP-23표준인에 근거하여 산출한 MIRD 5, 및 ORNL-TM 8381자료와 비교해 보았다. 그 결과 S-value는 한국 성인 남성 표준인에 기초한 모의 피폭체가 높은 값을 나타냈다. 이는 몸통이라는 특수한 공간에 위치하게 되는 선원장기(source organ) 및 표적장기(target organ)가 함유하고 있는 구성물질도 중요하지만 그에 못지않게 이들이 차지하고 있는 위치 및 방사성핵종의 특성 또한 중요하게 작용한다는 것을 알 수 있었다.

• Molecules and Cells
• /
• 제43권9호
• /
• pp.774-783
• /
• 2020

The lung has a vital function in gas exchange between the blood and the external atmosphere. It also has a critical role in the immune defense against external pathogens and environmental factors. While the lung is classified as a relatively quiescent organ with little homeostatic turnover, it shows robust regenerative capacity in response to injury, mediated by the resident stem/progenitor cells. During regeneration, regionally distinct epithelial cell populations with specific functions are generated from several different types of stem/progenitor cells localized within four histologically distinguished regions: trachea, bronchi, bronchioles, and alveoli. WNT signaling is one of the key signaling pathways involved in regulating many types of stem/progenitor cells in various organs. In addition to its developmental role in the embryonic and fetal lung, WNT signaling is critical for lung homeostasis and regeneration. In this minireview, we summarize and discuss recent advances in the understanding of the role of WNT signaling in lung regeneration with an emphasis on stem/progenitor cells.

• 디지털융복합연구
• /
• 제11권4호
• /
• pp.311-320
• /
• 2013

본 연구는 일 대학 간호과와 비 간호과 학생의 생명의료윤리 의식을 파악하여 대학생들의 올바른 생명윤리 의식 함양에 필요한 윤리교육의 방향과 교육과정 내용을 위한 기초자료를 제공하고자 시도하였다. 생명의료윤리 의식은 4점 만점에 간호과 학생들이 평균 3.04점으로 비 간호과 학생들의 2.88점보다 높았고 이들 간에 유의한 차이가 있었다(t=6.79, p<.001). 두 그룹간에 태아의 생명권, 태아진단, 신생아 생명권, 안락사, 장기이식, 뇌사영역에서 통계적으로 유의한 차이를 나타내었다. 대상자들의 생명의료윤리 의식에 영향을 미치는 주요 요인은 간호과에서는 한 학기 이상 윤리관련 수업 경험 유무, 생명윤리 관련 문제로 고민한 경험 유무, 윤리적 가치관이었고, 비 간호과는 학년으로 나타났다. 결과적으로 대상자들의 낮은 생명의료윤리 의식은 각 학과별로 기본적인 생명윤리 교육부터 고학년으로 올라갈수록 체계적이고 복합적인 윤리적 사고 판단과 의사결정 능력, 가치관 고취를 위한 교육과정을 통해 충족되어야 할 것이다. 추후 생명의료윤리 의식의 하위영역별 집중연구나 질적 연구를 제언한다.

• Journal of Chest Surgery
• /
• 제27권4호
• /
• pp.318-324
• /
• 1994

Cross-clamping of the descending thoracic aorta results in proximal hypertension,increase in left ventricular afterload,and impairment of distal organ perfusion. Bypass of the descending thoracic aorta is frequently advocated as an adjunct for repair of traumatic tears and degenerative aneurysms. Many methods of bypass have been proposed to provide distal perfusion and reduce left ventricular afterload during cross-clamping of the thoracic aorta. At Seoul National University Hospital, 7 patients were treated for the thoracic or thoracoabdominal aortic aneurysm using left atrium-femoral artery bypass with Bio-medicus centrifugal pump between October,1989, and January,1993. There were atherosclerotic thoracic aneurysm in 3 cases, thoracoabdominal aortic aneurysm due to chronic aortic dissection in 3 cases,aortic rupture due to trauma in 1 case. Total of 7 patients were operated by graft replacement with reimplantation of important branches. None of these cases developed severe complications and hospital death. We believe that the Bio-Medicus centrifugal pump is a simple and safe means of perfusing the lower body, kidneys, and spinal cord without necessitating heparinization.

• 한국전자통신학회논문지
• /
• 제13권4호
• /
• pp.897-902
• /
• 2018

본 연구는 D-F-M(Diagnose Fure Funktionelle Medizine) 이론을 기반으로 하여 신체 7부위에 13Hz의 양과 음의 임펄스전압을 인가함으로서 생성된 출력 파형을 이용하여 환자의 건강상태를 진단하는 생체신호 측정기의 개발에 관한 것이다. 측정기에서 취득한 데이터는 인공지능을 기반으로 한 귀납적 추론을 통하여 간엽조직 뿐만 아니라 신체기관의 상태를 진단하는 기기로서의 역할을 수행할 것으로 기대된다. 본 논문에서는 생체신호를 취득하고 관리하는 시스템 하드웨어에 주제를 한정할 것이다.