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Effects of Antarctic Ocean Krill Meal with NaF Oral Administration on Serum and Tissues in Rats

남극해 크릴 분말과 NaF 처리가 흰쥐의 혈청 및 조직에 미치는 영향

  • Kang, Dong-Soo (Department of Food Science and Technology, Pusan National University) ;
  • Jin, Dong-Hyeok (Department of Marine Bio Food Science, Chonnam National University) ;
  • Oh, Da-Young (Department of Marine Bio Food Science, Chonnam National University) ;
  • Lee, Young-Geun (Department of Marine Bio Food Science, Chonnam National University) ;
  • Kim, Han-Soo (Department of Marine Bio Food Science, Chonnam National University)
  • 강동수 (전남대학교 해양바이오식품학과) ;
  • 진동혁 (부산대학교 식품공학과) ;
  • 오다영 (부산대학교 식품공학과) ;
  • 이영근 (부산대학교 식품공학과) ;
  • 김한수 (부산대학교 식품공학과)
  • Received : 2018.07.03
  • Accepted : 2018.09.06
  • Published : 2018.11.30

Abstract

The purpose of this study was to probe the influences of krill (Euphausia superba) meal with NaF oral administration on a dose-effect relationship between fluoride levels of krill meal and serum enzyme activity such as alkaline phosphatase (ALP), aspartate aminotransferase (AST), alanine aminotransferase (ALT), and lactate dehydrogenase (LDH) in rats fed experimental diets for 5 weeks. There were no significant decreases in the activities of ALP, AST, ALT, and LDH in sera among krill meal diet groups (KF10, KF20, KF30). However, these groups were significantly (p<0.05) lower enzyme activities than normal diet (ND) plus NaF 10 mg group (NF). The fluoride levels of serum and organ tissues (liver, brain, heart, lung, kidney) in NaF 10 mg groups (NF, KF10, KF20, KF30) were significantly increased by adding krill meal in comparison with normal diet group. The results indicate that a difficult to found toxicity to the tissues from krill meal diet groups.

Keywords

References

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