• Proceedings of the Korean Society of Precision Engineering Conference
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• 2003.06a
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• pp.418-421
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• 2003

Specimens of Ti-10Ta-10Nb have been hot upset forged after heating to either the $\alpha$+$\beta$ and $\beta$-phase field. The variety temperatures (At 650, 700, 750, 800, 85$0^{\circ}C$) and strain rates (At 0.001, 0.01. 0.1, 1, 10 $s^{-1}$ ) were used. On the basis of flow stress data obtained as a function of temperature and strain rate in compression, a processing map for hot working has been developed. At strain rates lower than about 0.1 $s^{-1}$ and almost temperatures, processing efficiency exhibited high, but at 0.001 $s^{-l}$, and temperature 80$0^{\circ}C$, low because the Shear band has occurred. On the basis of the processing map, the optimum processing routes available for hot working of this material are outlined.d.

• Proceedings of the Korea Committee for Ocean Resources and Engineering Conference
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• 2000.10a
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• pp.63-67
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• 2000

Up to this day, Most studies of hydroelasticity are inclined to frequency domain atnlysis. Thos amlysis Q the landing, take-4, and dropping of airaqft on a structure. So, the concern of this prrper is a tra a VLFS subjected to dymmic lazd induced by airplane larndirrg and take-off. To predict added mass, dampr exciting force, the source-dipole distribution method were used The responses are accomplished by Fdoimain analysis method is based on Newmark $\beta$ method to pursuit time step pnzcedure taking advantage function for hvdrodvnumic effects.

• Journal of applied mathematics & informatics
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• v.7 no.3
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• pp.1017-1027
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• 2000

On the positive real number, we obtain the Hyers-Ulam stability and a stability in the sense of R. Ger for the generalized beta function g(x+p,y+q) = ${\varphi}(x,y)g(x,y)$ in the following settings: $$\mid$g(x+p,y+q)-{\varphi}(x,y)g(x,y)$\mid${\leq}{\delta}$ and $$\mid$\frac{g(x+p,y+q)}{\varphi(x,y)g(x,y)}-1$\mid${\leq}{\psi}(x,y). As a consequence we obtain stability theorems for the gamma functional equation and the beta functional equation.

• Korean Journal of Microbiology
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• v.30 no.1
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• pp.60-64
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• 1992

The secretion vector with promoter and signal sequence region of neutral protease gene (npr) from Bacillus amyloliquefaciens was constructed by the technique of polymerase chain reaction (PCR). A unique restriction iste was introduced into the 3' of the signal coding region by the synthesis of PCR primer. To demonstrate the function of cloned promoter and signal sequence, we used the E. coli .betha.-lactamase structural gene as a foreign gene. The signal sequence of .betha.-lactamase gene was deleted by Bal31 exonuclease and only mature region was introduced into the secretion vector. Bacillus subtilis cells transformed by the recombinant vector synthesized the fusion protein and were also capable of removing the signal peptide from the original fusion protein, as judged by the assay of .betha.-lactamase activity and secretion into the growth medium by western blotting.

• The Korean Journal of Food And Nutrition
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• v.20 no.2
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• pp.125-133
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• 2007

Ginger(Zingiber officinale Roscoe) has long been used as a food source in Korea, and it is widely used as a dietary condiment throughout the world. The present study focused on the immunomodulative effects of ginger extracts via in vitro experiments. To identify the immune-activation fractions of the plant, we performed the systematic fractionation of ginger with methanol, hexane, chloroform, butanol and water for separation and refining. The results showed that the chloroform fraction had the highest immune cell activation properties. In conclusion, this study suggests that ginger extracts may enhance immune function by regulating the splenocyte proliferation as well as the cytokine production capacity of activated macrophages.

• The Korean Journal of Applied Statistics
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• v.7 no.2
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• pp.9-19
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• 1994

Beta-binomial model, which is reparametrized in terms of the mean probability $\mu$ of a positive deagnosis and the $\kappa$ of agreement, is widely used in psychology. When $\mu$ is close to 0, inference about $\kappa$ become difficult because likelihood function becomes constant. We consider Bayesian approach in this case. To apply Bayesian analysis, Gibbs sampler is used to overcome difficulties in integration. Marginal posterior density functions are estimated and Bayesian estimates are derived by using Gibbs sampler and compare the results with the one obtained by using numerical integration.

• Molecules and Cells
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• v.20 no.2
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• pp.256-262
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• 2005

The neuronal cytoskeleton is essential for establishment of neuronal polarity, but mechanisms controlling generation of polarity in the cytoskeleton are poorly understood. The nonreceptor tyrosine kinase, Fer, has been shown to bind to microtubules and to interact with several actin-regulatory proteins. Furthermore, Fer binds p120 catenin and has been shown to regulate cadherin function by modulating cadherin-${\beta}$-catenin interaction. Here we show involvement of Fer in neuronal polarization and neurite development. Fer is concentrated in growth cones together with cadherin, ${\beta}$-catenin, and cortactin in stage 2 hippocampal neurons. Inhibition of Fer-p120 catenin interaction with a cell-permeable inhibitory peptide (FerP) increases neurite branching. In addition, the peptide significantly delays conversion of one of several dendrites into an axon in early stage hippocampal neurons. FerP-treated growth cones also exhibit modified localization of the microtubule and actin cytoskeleton. Together, this indicates that the Fer-p120 interaction is required for normal neuronal polarization and neurite development.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• v.43 no.2
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• pp.63-69
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• 2017

Nuclear factor I-C (NFI-C) plays a pivotal role in various cellular processes such as odontoblast and osteoblast differentiation. Nfic-deficient mice showed abnormal tooth and bone formation. The transplantation of Nfic-expressing mouse bone marrow stromal cells rescued the impaired bone formation in $Nfic^{-/-}$ mice. Studies suggest that NFI-C regulate osteogenesis and dentinogenesis in concert with several factors including transforming growth factor-${\beta}1$, $Kr{\ddot{u}}ppel$-like factor 4, and ${\beta}$-catenin. This review will focus on the function of NFI-C during tooth and bone formation and on the relevant pathways that involve NFI-C.

• Proceedings of the Korea Committee for Ocean Resources and Engineering Conference
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• 2001.05a
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• pp.103-107
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• 2001

When ship claps against the ocean structure sited at shallow water, the time simulation of motion responses of dolphin-moored ocean structure is presented. The equatien of motion based on Cummin's theory of impulse responses are employed, and solved in time domain by using the Newmark $\beta$ method. The added mass and damping coefficients involved in the equations are obtained from a three-dimensional panel method in the frequency domain. The impact forces due to ship collision are modeled as two method, and those are elastic and non-elastic collisions. The mooring forces for dolphin systems of scean structure are considered as linear spring system.

• Journal of Ocean Engineering and Technology
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• v.14 no.4
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• pp.1-8
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• 2000

The time simulation of motion responses of dolphin-moored BMP in waves is presented. The equation of motion based on Cummin's theory of impulse responses are employed, and solved in time domain by using the Newmark $\beta$ method. The hydrodynamic coefficient and first order wave exciting forces involved in the equations are obtained from a three-dimensional panel method in the frequency domain. The second order wave drift forces and mooring for dolphin system are taken into account. As for numerical example, time domain analysis are carried out for a BMP in irregular wave condition.