• Title/Summary/Keyword: behavior modification

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Effect of TESPT Silane Coupling Agent on Mechanical Properties of Precipitated Silica Filled NBR Compound for Oil Seal (TESPT 실란커플링제가 침전 실리카로 보강된 오일씰용 NBR복합소재의 기계적 물성에 미치는 영향)

  • Lee, Young-Seok;Hwang, Ki-Seob;Lee, Jong-Cheol;Kim, Tae-Geun;Ha, Ki-Ryong
    • Elastomers and Composites
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    • v.46 no.1
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    • pp.45-53
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    • 2011
  • The effect of the silane coupling agent, bis(triethoxysilypropyl)tetrasulfide (TESPT), on mechanical properties of a silica-filled NBR compound for oilseal was investigated. Curing behavior and crosslinking density of the compounds were measured using ODR (oscillating disk rheometer) and swelling ratio in toluene. UTM (universal testing machine) and shore A hardness tester were used in order to study the characteristics of mechanical properties of original vulcanizates and aged ones with heated air and ASTM No. 3. oil. Recovery of elasticity which influences the performance and service life of oilseal was investigated by giving bending deformation to vulcanizates in aging condition. After bending aging test, recovery distance was measured and calculated angle of recovery from it. TR (temperature retraction) test was performed on these vulcanizates to determine the low temperature recovery behavior. Wear resistance was measured by Taber type abrasion tester. In addition, SEM was used to characterize the morphology of the worn surface of vulcanizates. The result showed that addition of TESPT into silica-filled compound improves not only compound flow-ability, interaction between NBR and silica and crosslinking density, but also hardness, 100% modulus, recovery of elasticity, wear resistance, heat resistance and ASTM No.3 oil resistance of vulcanizates.

Evaluation and Modification of Tensile Properties of Carbon Fiber Reinforced Polymer(CFRP) as Brittle Material with Probability Distribution (확률분포를 이용한 취성재료 특성의 탄소섬유보강폴리머 인장물성평가 및 보정)

  • Kim, Yun-Gon
    • Journal of the Korea institute for structural maintenance and inspection
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    • v.23 no.3
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    • pp.17-24
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    • 2019
  • Carbon Fiber Reinforced Polymers(CFRP) has widely utilized as a material for rehabilitation because of its light-weight, deformability and workability. Because CFRP is brittle material whereas steel is ductile, it is inappropriate to apply conventional design approach for steel reinforcement. For ductile material, the behavior of combined elements is on average of that of unit element due to the stress redistribution between elements after yielding. Therefore, the mean value of the stress of combined elements is equal to that of unit element and the standard variation is smaller. Therefore, although the design value can increase, it is used as constant value because it is conservative and practical approach. However, for brittle material, the behavior of combined elements is governed by the weaker element because no stress redistribution is expected. Therefore, both the mean value and standard variation of the stress of combined elements decreases. For this reason, the design value would decrease as the number of element increases although it is eventually converged. In this paper, in brittle material, it is verified that the combination of unit element with normal distribution results in combined element with weibull distribution, so the modifying equation of mechanical properties is proposed with respect to the area load applied.

Effect of Self-care Education at a Diabetes Camp on Diabetes Management Behaviors, Knowledge and Self-efficacy in Children with Type 1 Diabetes (당뇨병 캠프의 자가간호 교육이 제1형 당뇨병 아동의 당뇨관리행위, 당뇨지식 및 당뇨관리 자아효능감에 미치는 영향)

  • Kang, Narae;Ahn, Youngmee;Lee, Ji Eun;Sohn, Min
    • Child Health Nursing Research
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    • v.20 no.3
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    • pp.168-175
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    • 2014
  • Purpose: Study purposes were to exam effects of self-care education for children with type 1 diabetes on their diabetes management behaviors and to explore the relationship among diabetes management behaviors, knowledge, self-efficacy and clinical variables. Methods: This study was a one group quasi-experimental study. Study participants were children with type 1 diabetes and attended a four hour self-care education of a diabetes camp. Data were collected using structured questionnaires including Diabetes Management Behavior Scale (DMBS), Michigan Diabetes Research and Training Center's Brief Diabetes Knowledge Test and Self-Efficacy for Diabetes Self-Management. Results: The mean age of the participants was 12 (${\pm}2.3$) years. After the education, their DMBS and knowledge improved, but the improvement was not statistically significant (t=1.758, p=.101; t=0.528, p=.606). Two areas of DMBS, daily prevention behaviors and modification of care plan, were associated with study variables. Daily prevention behaviors were associated with duration of diabetes (r=.653, p=.008), HbA1c (r=.563, p=.038) and having a complication (r=-2.788, p=.015). Modification of care plan was associated with age at diagnosis (r=-.552, p=.033). Conclusion: Children with type 1 diabetes could improve some parts of their diabetes management behaviors even after a short diabetes camp.

An Analytic Study on Influencing Factors for Sexual Satisfaction in Women Who have had a Hysterectomy (자궁절제술 부인의 성생활 만족에 관한 요인 분석)

  • 장순복
    • Journal of Korean Academy of Nursing
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    • v.19 no.2
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    • pp.160-172
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    • 1989
  • This research was done to clarify the factors related to sexual satifaction in women who have had a hysterectomy, and to idenify which factors had statistically significant influence of sexual satisfaction of the subjacts. The objective of this study was to identify the variables related to sexual adaptation which might be changed by nursing intervention. This was a cross-sectional descriptive correlation study. There were 230 subjects in the study, and they were selected by a convenient sampling method. The tool. for this study was developed by the researcher through modification of the Dergatis Sexual Function Inventory(DSFI). A pilot study was done to determine the necessary modifications. Data collection was done between Sept. 1987 and Du. 1987 using a mailed questionnaire. The characteristics of the subjects were as follows : The mean age of the subjects was 42.3 years and 204(87.4%) of the subjects had nine or more years of education. The mean income of the subjects was 85.8870 won / month, and 179(77%) of them were housewives. The mean number of pregnancies and children were 4.9 and 2.5 respectively. Oophorectomies were included in the surgery for 66(28.7%) of the subjects. Only 12(5.2%) were planning to have more children. Only 88(38.3%) of the subjects had received information prior to the surgery regarding health problems related to the operation and less than half, 111 (48.3%), had received this kind of information before discharge. Lay persons were the source of information about the post-operation status for 196 (85.2%) of the subjects, but the content of the information did not significantly influence the sexual satisfaction score. Only 16(7.0%) of the subjects said they regretted having a hysterctomy while 102(44.3%) said they were pleased to have had a hysterectomy. Ninety (39.1 %) of the subjects reported that their husbands had “stress” and 164(71.3%) of the subjects reported “stress”. The results of this study are summarized as follows : 1. The mean score for sexual satisfaction of the subjects was 34.24 with a possible maximum score of 50.00. Eighty two(35.8%) were responded that they were satisfied with their sexual life but 61 (26.5%) were responded that they were dissatisfied with their sexual life 2. The following 15 factors extracted from the results of the data analysis were significantly related to sexual satisfaction(p<.05) ; support of husband, body image, emotion, knowledge of sex, menopausal symptoms, sexual behavior, the feelings the subjects had about the hysterectomy, stress for both subject and husband, the number of children, health information given before operation, job, age, level of education and income. The five most important factors influencing sexual satisfaction were identified by using stepwise multiple regression analysis. The most important factor was support of husband, which explained 17.83% of the total variance. The remaining factors in order of significance were : Knowledge of sex, income, job, and emotional status. Those five factors explained 35.16% of the sexual satisfaction. In conclusion, for the care of women who are going to be discharged from hospital after having had a hysterctomy, nurses have to work with the husbands to help them to understand the importance of their support. Nurses also need to make sure that the subjects have an adequeate knowledge of sexual life after a hysterectomy. Also nursing interventions should focus on subjects who do not have a job, who are of low economic status, and the subjects who are under the unpleasant mood.

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Epigenetic Responses Programmed by Prenatal Stress : $F_1$ Male Rat Model (출생 전 스트레스에 의해 프로그램된 후생학적 반응 : $F_1$ 수컷 흰쥐 모델)

  • Lee, Sung-Ho
    • Development and Reproduction
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    • v.12 no.2
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    • pp.117-124
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    • 2008
  • The efficient strategies to cope with unpredictable and/or harmful environmental changes have been developed by every organism in order to ensure its survival and continuity of it's own species. As a results, all living things on earth maintain dynamically internal stability via a process termed 'homeostasis' among physiological parameters despite of external environment changes. Stress is an emotional and physical response to threat homeostasis. Stress may have not only transient but rather permanent effect on the organism; recent evidence clearly show that prenatal stress could organize or imprint permanently physiological systems without any change in genetic codes, a process known as 'epigenetic programming'. In this review, a series of reproduction-associated events occurred in prenatally stressed male rats such as alteration in the structure of sexually dimorphic brain regions, modification of neurotransmitter metabolism, changes in reproductive endocrine status, and finally, disorders of sexual behavior will be introduced. The fetal brain is highly sensitive to prenatal programming and glucocorticoids in particular have powerful brain-programming properties. The chronic hyperactivation of fetal brain by maternal stress-induced glucocorticoid input will provide new program via increasing the neuroplasticities. This 'increased neuroplasticities' will be the basis for the 'increased phenotypic plasticities' rendering the organism's better adaptation to environmental challenges. In conclusion, organism who experienced 'harsh' environment in his fetal life seems to give up a certain portion of reproductive competence to make good chance of survival in his future life by epigenetic (re)programming.

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Bond Characteristics of High-Strength Light-Weight Concrete (고강도 경량 콘크리트의 부착특성)

  • Shin, Sung-Woo;Lee, Kwang-Soo;Choi, Myung-Shin;Kim, Hyun-Sik
    • Magazine of the Korea Concrete Institute
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    • v.11 no.2
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    • pp.77-84
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    • 1999
  • Recently, it is increased the use of High-Strength Light-Weight Concrete(HLC) in the high-rise buildings and mega-structures. But there are a few research on the bond behavior of HLC, so it need to study about that. The present study was performed to investigate the bond characteristics of HLC. Major test variables include concrete compressive strength(f'c), concrete cover(c), bond length (${\ell}_{db}$), and bar diameter($d_b$). Test results indicate that the bond stress of HLC is increased with the increment of $\sqrt{f'_c}$ and concrete cover, bond stress is decreased with increment of bond length and bar diameter. And the final failure mode such as splitting or pullout failure is significantly affected by the concrete cover to bar diameter ratios(C/$d_b$). Test results were compared with ACI code and other proposed equations. The bond stress of HLC is higher than that of normal-strength normal-weight concrete, but lower than that of high-strength normal-weight concrte. Considering the present test results, modification factor(${\lambda}$= 1.3) of bond length in ACI 318-95 code for light-weight concrete is may have to be reviewed to apply to HLC.

Human Embryonic Stem Cells Co-Transfected with Tyrosine Hydroxylase and GTP Cyclohydrolase I Relieve Symptomatic Motor Behavior in a Rat Model of Parkinson′s Disease

  • Kil, Kwang-Soo;Lee, Chang-Hyun;Shin, Hyun-Ah;Cho, Hwang-Yoon;Yoon, Ji-Yeon;Lee, Gun-Soup;Lee, Young-Jae;Kim, Eun-Young;Park, Se-Pill
    • Proceedings of the Korean Society of Developmental Biology Conference
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    • 2003.10a
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    • pp.101-101
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    • 2003
  • Main strategy for a treatment of Parkinson's disease (PD), due to a progressive degeneration of dopaminergic neurons, is a pharmaceutical supplement of dopamine derivatives or ceil replacement therapy. Both of these protocols have pros and cons; former exhibiting a dramatic relief but causing a severe side effects on long-term prescription and latter also having a proven effectiveness but having availability and ethical problems Embryonic stem (ES) cells have several characteristics suitable for this purpose. To investigate a possibility of using ES cells as a carrier of therapeutic gene(s), human ES (hES, MB03) cells were transfected with cDNAs coding for tyrosine hydroxylase (TH) in pcDNA3.1 (+) and the transfectants were selected using neomycin (250 $\mu /ml$). Expression of TH being confirmed, two of the positive clone (MBTH2 & 8) were second transfected with GTP cyclohydrolase 1 (GTPCH 1) in pcDNA3.1 (+)-hyg followed by selection with hygromycin-B (150 $\mu /ml$) and RT-PCR confirmation. By immune-cytochemistry, these genetically modified but undifferentiated dual drug-resistant cells were found to express few of the neuronal markers, such as NF200, $\beta$-tubulin, and MAP2 as well as astroglial marker GFAP. This results suggest that over-production of BH4 by ectopically expressed GTPCH I may be involved in the induction of those markers. Transplantation of the cells into striatum of 6-OHDA- denervated PD animal model relieved symptomatic rotational behaviors of the animals. Immunohistochemical analyses showed the presence of human cells within the striatum of the recipients. These results suggest a possibility of using hES cells as a carrier of therapeutic gene(s).

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BIOLOGICAL RESPONSES OF OSTEOBLAST-LIKE CELLS TO DIFFERENT TITANIUM SURFACE BY ANODIZING MODIFICATION

  • Kim Myung-Joo;Kim Chang-Whe;Lim Young-Jun;Park Hyun-Joo
    • The Journal of Korean Academy of Prosthodontics
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    • v.43 no.6
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    • pp.751-763
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    • 2005
  • Statement of problem. To improve a direct implant fixation to the bone, various strategies have been developed focusing on the surface of materials. The surface quality of the implant depends on the chemical, physical, mechanical and topographical properties of the surface. The different properties will interact with each other and a change in thickness of the oxide layer may also result in a change in surface energy, the surface topography and surface, chemical composition. However, there is limited the comprehensive study with regard to changed surface and biologic behavior of osteoblast by anodization. Purpose of study. The aim of this study was to analyze the characteristics of an oxide layer formed and to evaluate the cellular biologic behaviors on titanium by anodic oxidation (anodization) by cellular proliferation, differentiation, ECM formation and gene expression. And the phospholipase activity was measured on the anodized surface as preliminary study to understand how surface properties of Ti implant are transduced into downstream cellular events. Methods and Materials. The surface of a commercially pure titanium(Grade 2) was modified by anodic oxidation. The group 1 samples had a machined surface and other three experimental specimens were anodized under a constant voltage of 270 V(Group 2), 350 V(Group 3), and 450 V(Group 4). The specimen characteristics were inspected using the following five categories; the surface morphology, the surface roughness, the thickness of oxide layer, the crystallinity, and the chemical composition of the oxide layer. Cell numbers were taken as a marker for cell proliferation. While the expression of alkaline phosphatase and Runx2 (Cbfa1) was used as early differentiation marker for osteoblast. The type I collagen production was determined, which constitutes the main structural protein of the extracellular matrix. Phospholipase $A_2$ and D activity were detected. Results. (1) The anodized titanium had a porous oxide layer, and there was increase in both the size and number of pores with increasing anodizing voltage. (2) With increasing voltage, the surface roughness and thickness of the oxide film increased significantly (p<0.01), the $TiO_2$phase changed from anatase to rutile. During the anodic oxidization, Ca and P ions were more incorporated into the oxide layer. (3) The in vitro cell responses of the specimen were also dependant on the oxidation conditions. With increasing voltage, the ALP activity, type I collagen production, and Cbfa 1 gene expression increased significantly (p<0.01), while the cell proliferation decreased. (4) In preliminary study on the relation of surface property and phospholipase, PLD activity was increased but $PLA_2$ activity did not changed according to applied voltage. Conclusion. The anodized titanium shows improved surface characteristics than the machined titanium. The surface properties acquired by anodization appear to give rise more mature osteoblast characteristics and might result in increased bone growth, and contribute to the achievement of a tight fixation. The precise mechanism of surface property signaling is not known, may be related to phospholipase D.

Ion beam irradiation for surface modification of alignment layers in liquid crystal displays (액정 디스플레이 배향막을 위한 이온빔 표면조사에 관한 연구)

  • Oh, Byeong-Yun;Kim, Byoung-Yong;Lee, Kang-Min;Kim, Young-Hwan;Han, Jeong-Min;Lee, Sang-Keuk;Seo, Dae-Shik
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2008.04a
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    • pp.41-41
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    • 2008
  • In general, polyimides (PIs) are used in alignment layers in liquid crystal displays (LCDs). The rubbing alignment technique has been widely used to align the LC molecules on the PI layer. Although this method is suitable for mass production of LCDs because of its simple process and high productivity, it has certain limitations. A rubbed PI surface includes debris left by the cloth, and the generation of electrostatic charges during the rubbing induces local defects, streaks, and a grating-like wavy surface due to nonuniform microgrooves that degrade the display resolution of computer displays and digital television. Additional washing and drying to remove the debris, and overwriting for multi-domain formation to improve the electro-optical characteristics such as the wide viewing angle, reduce the cost-effectiveness of the process. Therefore, an alternative to non-rubbing techniques without changing the LC alignment layer (i.e, PI) is proposed. The surface of LC alignment layers as a function of the ion beam (IE) energy was modified. Various pretilt angles were created on the IB-irradiated PI surfaces. After IB irradiation, the Ar ions did not change the morphology of the PI surface, indicating that the pretilt angle was not due to microgrooves. To verify the compositional behavior for the LC alignment, the chemical bonding states of the ill-irradiated PI surfaces were analyzed in detail by XPS. The chemical structure analysis showed that ability of LCs to align was due to the preferential orientation of the carbon network, which was caused by the breaking of C=O double bonds in the imide ring, parallel to the incident 18 direction. The potential of non-rubbing technology for fabricating display devices was further conformed by achieving the superior electro-optical characteristics, compared to rubbed PI.

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Behavior of 550MPa 43mm Hooked Bars Embedded in Beam-Column Joints (보-기둥 접합부에 정착된 550 MPa 43 mm 갈고리철근의 거동)

  • Bae, Min-Seo;Chun, Sung-chul;Kim, Mun-Gil
    • Journal of the Korea Concrete Institute
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    • v.28 no.5
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    • pp.611-620
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    • 2016
  • In the construction of nuclear power plants, only 420 MPa reinforcing bars are allowed and, therefore, so many large-diameter bars are placed, which results in steel congestion. Consequently, re-bar works are difficult and the quality of RC structures may be deteriorated. To solve the steel congestion, 550 MPa bars are necessary. Among many items for verifying structural performance of reinforced concrete with 550 MPa bars, the 43 mm hooked bars are examined in this study. All specimens failed by side-face blowout and the side cover explosively spalled at maximum loads. The bar force was initially transferred to the concrete primarily by bond along a straight portion. At the one third of maximum load, the bond reached a peak capacity and began to decline, while the hook bearing component rose rapidly. At failure, most load was resisted by the hook bearing. For confined specimens with hoops, the average value of test-to-prediction ratios by KCI code is 1.45. The modification factor of confining reinforcement which was not allowed for larger than 35 mm bars can be applied to 43 mm hooked bars. For specimens with 70 MPa concrete, the average value of test-to-prediction ratios by KCI code is 1.0 which is less than the values of the other specimens. The effects of concrete compressive strength should be reduced. An equation to predict anchorage capacity of hooked bars was developed from regression analysis including the effects of compressive strength of concrete, embedment length, side cover thickness, and transverse reinforcement index.