• The Journal of the Society of Stroke on Korean Medicine
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• v.19 no.1
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• pp.55-62
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• 2018

A patient with right upper limb weakness was diagnosed with idiopathic polyneuropathy and received a series of Korean Medicine including acupuncture, electroacupuncture, bee venom acupuncture, and administration of herbal medicine BacJung-hwan for 17 days of hospitalization period. The progression of the weakness was measured by Hand grip tester, neuralgia and numbness were measured by the NRS(Numerical Rating Scale) scores. After treatment, the right grip strength improved from 12kg to 35kg and the right upper limb neuralgia of the NRS5 was improved to NRS2. The present case study suggests that the potential effects of Korean Medicine treatment for idiopathic polyneuropathy.

• Journal of Korean Medicine Rehabilitation
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• v.33 no.3
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• pp.115-127
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• 2023

Objectives Through this study, we investigated the effects of Korean medicine treatments on range of motion recovery and pain reduction in patients with Frozen shoulder. Methods In this study, the medical records of 26 patients diagnosed with frozen shoulder were retrospectively observed and analyzed through the IBM SPSS Statistics 25 program. We used range of motion to observe the patient's motion recovery and numeric rating scale to evaluate pain reduction. Results The shoulder range of motion increased statistically significantly from 160.0 (123.5~170.0) to 170.0 (160.0~180.0) (flexion), 115.0 (90.0~135.0) to 167.5 (130.0~178.8) (abduction), 40.8±22.1 to 58.3±16.0 (external rotation) (p<0.001). The average of numeric rating scale reduced statistically significantly from 6.7±2.0 to 3.2±1.4 (p<0.001). Depending on the period, the range of motion increased statistically significantly when visited within 3 months, also the pain score decreased 7.0 (5.4~8.0) to 3.0 (1.8~3.6) statistically significantly when visited within 3 months. In the treatment intervention, the increase in the range of motion and the decrease in pain were statistically significant, especially when the bee venom acupuncture and chuna manaul therapy were used together. Conclusions Korean medicine treatments was effective in improving the range of motion and reducing pain in frozen shoulders. In particular, when treated within 3 months of onset and when bee venom acupuncture and chuna manual therapy were used together, it was effective in recovering the range of motion and reducing pain.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.12
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• pp.4753-4758
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• 2014

In recent times, a number of studies have provided evidence that biotoxins present great potential as antitumor agents, such as snake venom, bee venom, some bacteria toxins and plant toxins, and thus could be used as chemotherapeutic agents against tumors. The biodiversity of venoms and toxins make them a unique source from which novel anticancer agent may be developed. Biotoxins, also known as natural toxins, include toxic substances produced by plants, animals and microorganisms. Here, we systematically list representative biological toxins that have antitumor properties, involving animal toxins, plant toxins, mycotoxins as well as bacterial toxins. In this review, we summarize the current knowledge involving biotoxins and the active compounds that have anti-cancer activity to induce cytotoxic, antitumor, immunomodulatory, and apoptotic effects in different tumor cells in vivo or in vitro. We also show insights into the molecular and functional evolution of biotoxins.

• Korean journal of applied entomology
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• v.46 no.2
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• pp.229-234
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• 2007

Pure Bombus ignitus venom samples were submitted to two-dimensional gel electrophoresis. A total of 64 excised spots were analyzed by mass spectrometry. Three main proteins resulted in the identification have not been described in other bee venoms before. Dose-dependence against human carcinoma (Hep3B, BT-20, A549 and AGS) were observed from 1ng/ml to 100ng/ml. Expecially, the treatment of 100ng/ml B. ignitus venoms showed the highest cytotoxicity with 55% against hepatocellular carcinoma (Hep3B). The B. ignitus venoms showed strong antimicrobial activities against Enterococcus faecium and Shigella sonnei, and practically antimicrobial activity against the other microorganisms tested. The minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of E. faecium and S. sonnei, were 0.256ug/ml, respectively.

• Journal of Korean Medicine Rehabilitation
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• v.31 no.1
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• pp.119-135
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• 2021

Objectives This review aims to analyze the current research trend in the usage of bee venom (BV) acupuncture for articular diseases of single type joint. Methods We collected 74 articles on BV acupuncture clinical study for articular diseases of single joint by searching Korean web databases 'Journal of Korean Medicine Rehabilitation', 'Oriental Medicine Advanced Searching Integrated System', 'Korean Traditional Knowledge Portal' from 1999 to 2020 August. Results We summarized the most frequent clinical treatment methods of BV acupuncture for articular diseases of single type joint. Research focused on specific diseases in application of BV acupuncture about some articular type diseases of single joint. It is assumed that the details of treatment for each joint are not related to the type of joint. In clinical study of BV acupuncture, reproducibility was mostly insufficient. Conclusions BV acupuncture clinical study for articular diseases of single joint should be proceed for a number of subjects, to treat various types of disease, by using more safe and detailed treatments.

• Journal of Korean Medicine Rehabilitation
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• v.20 no.4
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• pp.241-254
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• 2010

Anterior cruciate ligament tear is a common disease of knee injury. We report 1 case of anterior cruciate ligament complete tear diagnosed by MRI(magnetic resonance imaging) imaging and 1 case after reconstruction. Outcomes were measured by visual analogue scale(VAS) and Lysholm knee scoring scale. We applied acupuncture treatment, bee venom injection, bongchuna and prescribed herbal medication. Patients who treated by oriental medical treatments had a significant effect on the pain decrease and range of motion and knee function. Oriental medical treatments are very useful on pain reduction and prevention of muscle contraction, leading to satisfied rehabilitation, as wee as diminishing recurrence after operation.

• The Journal of Churna Manual Medicine for Spine and Nerves
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• v.3 no.2
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• pp.43-52
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• 2008

Objective : The purpose of this study is to evaluate the conservative treatment for supraspinatus tendinitis with kyphotic cervical curvature patient. Methods : We used chuna, Herbal medication, Acupuncture, Bee Venom Acupuncture, Physical Therapy for this patient. And we measured of VAS score, ROM and Extent of the subjective symptoms of shoulder pain to evaluate treatment effects. Result : Patient's shoulder pain and cervical curvature has improved. VAS score and Extent of the subjective symptoms of shoulder pain score were also decreased.

• Journal of Acupuncture Research
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• v.29 no.4
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• pp.71-79
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• 2012

Objectives : The purpose of this study is to set the explanatory duty on traditional Korean medical(TKM) treatment by analyzing the judicial precedents. Methods : The study was performed by analyzing nine cases of lawsuits related to Korean medicine doctor and explanatory duty among the medical dispute cases in Korea from 1968 through 2012. Results : Nine closed claims occurred regarding the violation of explanatory duties in the field of TKM practice. Two claims were decided by supreme court, three were decided by high court, and four were decided by district court. The causes of lawsuits were categorized as follows : bee venom pharmacopuncture, herb treatment, and an explanation for safety. Conclusions : To perform an explanatory duty has important legal implications for the protection of patients' rights and Korean Medicine doctors' autonomy on TKM treatment.

• Proceedings of the Korea Environmental Mutagen Society Conference
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• 2003.10a
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• pp.117-117
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• 2003

• Journal of Pharmacopuncture
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• v.14 no.2
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• pp.61-74
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• 2011

This is a case report about effect of syeom pharmacopuncture, bee venom and autohemo-seperated regeneration pharmacopuncture(ASRP) for acute traumatic subdeltoid bursitis with partial tear of subscapularis tendon, which was diagnosed by symptoms and MRI(Magnetic resonance imaging) and caused by bongchuna treatment. We evaluated the patient using Visual Analogue Scale(VAS) every two or four days and range of movement(ROM), physical examination of shoulder about one per ten days and observed improvement with reexamination by ultrasonography and MRI as well. Pharmacopuncture rapidly reduced pain and improved range of motion and function of shoulder in patients with acute sub-deltoid bursitis even though it was severe symptom. Our result suggest that autohemo-seperated regeneration pharmacopuncture might be effective in regenerating the tear of soft tissue such as subscapularis tendon.