• 한국문헌정보학회지
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• 제38권1호
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• pp.77-91
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• 2004

본 연구는 장애척도를 이용한 서울 소재 대학도서관 사서가 인식하는 연구활용장애에 관한 실증적 연구이다. 본 연구결과, 장애척도의 평균은 조직체요인이 가장 높았고, 의사소통요인, 연구요인, 사서요인 순이었다. 전반적으로 대학사서들은 새로운 아이디어 수행시간의 부족, 시설의 부적합 업무절차 변경의 권위부족과 관계된 조직체 요인, 그리고 실무수행 언급의 불명확함, 실무 관련성 결여와 연구문헌 읽기의 용이성 부족과 관계된 의사소통의 요인에서 장애를 크게 인식하고 있었다. 또한 영어논문과 통계분석 이해의 어려움도 주요 장애 요인으로 언급되었다. 간호직 연구와의 비교결과 두 실무직은 새로운 아이디어 수행 시간의 부족 등을 공통적인 장애로 인식하고 있었다. 이러한 장애를 해결하기 위해서는 문헌정보학 교육 영역에서는 '연구활용능력'의 강화 필요성. 연구영역에서는 연구자와 실무자간의 의사소통격차의 해소 노력, 실무영역에서는 연구활용을 촉진하는 다양한 보상제도의 활성화 방안이 제시되어야 한다. 본 연구의 후속 연구에서는 사서가 실무에서 직면하는 연구활용의 구체적인 경험들을 질적 접근으로 탐구할 필요가 있다. 또한 양적 연구와 질적 연구결과를 상호보완적으로 통합하여 사서직의 연구활용 장애를 사정할 수 있는 표준도구를 개발하고, 적용할 필요가 있다.

• 근관절건강학회지
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• 제5권2호
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• pp.174-190
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• 1998

Osteoporosis has been known as a common complication of rheumatoid arthritis and a major preventable health problem. Lots of studios have demonstrated that changes in life style can help delay or prevent osteoporosis. Therefore nursing intervention related osteoporosis prevention have consisted of education programs aimed at changing dietary and exercise habit. However knowledge gained from education haven't always leaded to behavior change. Therefore it is important to consider other psychological variables in effecting behavior change. Numerous research have found self efficacy and health belief to be an important factor in individual decision making behavior. The purpose of the study was to develop health belief and efficacy expectation promoting program based on Health Belief Model & Self Efficacy Model and to investigate its effects in women with rheumatoid arthritis. For this purpose, one group pretest-post design was used. The subject of the study were 16 women with rheumatoid arthritis in Pusan city and data collection was carried out from April, 1997 to May, 1998. The intervention program was consisted of educating on osteoporosis and enhancing and reinforcing self efficacy by verbal persuasion during the period of 4 weeks. The instruments were used to collect data in this study were Osteoporosis Health Belief Scale, Osteoporosis Self Efficacy Scale, and Osteoporosis Preventive Behavior Scale. Data was analyzed by Wilcoxon signed rank test using SPSS $PC^+$ program. The results are as follows : 1) The behavior should be increased after intervention was supported(Z=-3.5162, p=.0004, diet : Z=-3.2942, p=.0010, exercise). 2) The sub-hypothesis that perceived sensitivity should be increased after intervention was supported (Z=-2.3854, p=.0171). 3) The sub-hypothesis that perceived severity should be increased after intervention was rejected(Z=-1.4327, p=.1520). 4) The sub-hypothesis that perceived benefit should be increased after intervention was supported(Z=-2.6410, p=.0083). 5) The sub-hypothesis that perceived barrier should be decreased after intervention was supported (Z=-2.4138, p=.0158). 6) The sub-hypothesis that efficacy expectation should be increased after intervention was supported(Z=-3.5162, p=.0004). As a conclusion, it was found that health belief and self efficacy promoting program was an effective nursing intervention for preventing osteoporosis of rheumatoid arthritis.

• 한국직업건강간호학회지
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• 제6권2호
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• pp.156-167
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• 1997

In Korea, based on the Revised Law of Occupational Safety and Health a new entity of institution was set up in 1990 to provide occupational health services to SSE in which three sorts of personnel as a team have to be involved. These institutions, in charge of scores to hundreds of workplace area-wide, have been providing occupational health services without payment from employers or employees, and government reimburses through the Occupational Injury Prevention Insurance since 1993. As a service provider, a team is composed of doctors, nurses and industrial hygienists. Undergraduate and postgraduate educations for the SSE occupational health are not specified and the question on the performance of the personnel has been raised. This study was designed to analyze the facilitating factors of and barriers to the performance and its improvement of these personnel. In 1997, the survey was conducted with all 58 institutions. Structured questionnaires were mailed to 200 personnel who were providing the occupational health service for SSE. The response rate was 51.7% for doctors, 58.6% for nurses, and 60.3% for industrial hygienist, respectively. Results are as follows : 1) There is a guideline for occupational service mandated by the government. Under the guideline, the minimum frequency of visiting workplace is assured with six times of doctors, 17 times for nurse and industrial hygienist in a year. There are one doctor for every 200 factories, one nurse and one hygienist for every 100 factories. 2) All respondents have basic qualification for occupational health service. About 16.7%. of doctors are certified in industrial medicine or preventive medicine, and 64.7% of industrial hygienists had first grade certification. Totally 66.7% of personnel have been involved in occupational health for more than one year. 3) As a support system for the performance improvement, 66.3% respond that they have been provided with educational materials, advice related to industrial environment and guidance of MSDS from Korea Industrial Safety Corporation. Most respondents indicate the lack of concern of employers and employees as a main barrier to the improvement of the service. Also they are in the need of the training opportunity more focused on SSE. The Governments policy for SSE is a principal facilitating factor. Training program focused on SSE situation, manpower, technical support, etc. are areas to be improved to have a better occupational health service for SSE in Korea.

• 한국수정란이식학회지
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• 제33권3호
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• pp.129-137
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• 2018

Acute vascular rejection has been known as a main barrier occurring in a xenograted tissue of alpha 1,3-galactosyltransferase knock-out (GalT KO) pig into a non-human primate (NHP). Adenosine which is a final metabolite following sequential hydrolysis of nucleotide by ecto-nucleotidases such as CD39 and CD73, act as a regulator of coagulation, and inflammation. Thus xenotransplantation of CD39 and CD73 expressing pig under the GalT KO background could lead to enhanced survival of recipient NHP. We constructed a human CD39 and CD73 expression cassette designed for endothelial cell-specific expression using porcine Icam2 promoter (pIcam2-hCD39/hCD73). We performed isolation of endothelial cells (pAEC) from aorta of 4 week-old GalT KO and membrane cofactor protein expressing pig ($GalT^{-MCP/-MCP}$). We were able to verify that isolated cells were endothelial-like cells using immunofluorescence staining analysis with von Willebrand factor antibody, which is well known as an endothelial maker, and tubal formation assay. To find optimal condition for efficient transfection into pAEC, we performed transfection with GFP expression vector using four programs of nucleofection, M-003, U-023, W-023 and Y-022. We were able find that the program W-023 was optimal for pAEC with regard to viability and transfection efficiency by flow cytometry and fluorescent microscopy analyses. Finally, we were able to obtain $GalT^{-MCP/-MCP}/CD39/CD73$ pAEC expressing CD39 and CD73 at levels of 33.3% and 26.8%, respectively. We suggested that pACE isolated from $GalT^{-MCP/-MCP}$ pig might be provided as a basic resource to understand biochemical and molecular mechanisms of the rejections and as an alternative donor cells to generate $GalT^{-MCP/-MCP}/CD39/CD73$ pig expressing CD39 and CD73 at endothelial cells.

• 가정간호학회지
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• 제9권2호
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• pp.103-113
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• 2002

Purpose: This study was conducted to explore the relationship among health belief. health locus of control and patients sick-role behavior compliance of diabetic mellitus patients visiting public health center. Method: The subjects of this study were 193 of the diabetic patients who were visiting 4 Public Health Center in B city. The instrument used for measuring health belief was Park's(1985). for health locus of control was Wallston. et al's(1978) and for sick-role behavior compliance was Park's(1984). The data were collected with structured questionnaires; total 58 items contained about health belief. health locus of control and sick-role behavior compliance from 1st to 31st July. 2001. The data was analyzed by the SPSS/PC programs using t-test. Pearson's correlation coefficient. ANOVA and Scheffe-test. Result: The average score of the health belief was $57.99\pm9.45$ health locus of control was $66.83\pm9.48$ and sick-role behavior compliance was $42.81\pm7.00$. Statistically significant factors influencing the health belief among social demographic characteristics were family number(F=3.818. p=0.024), monthly income(F=5.153, p=0.002), time of diagnosis(F=3.937. p=0.002) and difficult to control disease(F=5.803. p=0.000). The significant factors influencing the health locus of control were marital status(F=4.669. p=0.010). Also significant factors influencing the sick-role behavior compliance were monthly incomes(F=5.245, p=0.000). the time of diagnosis(F=4.424. p=0.001) and admission to hospital with diabetes(F=9.031. p=0.000). There was negative mild correlation comparatively between health belief and sickrole behavior compliance(r=-0.142, p<0.05) but no correlation in sensitiveness/severity, barrier, benefit(p<0.05). There was no correlation between internal. external. chance health locus of control and sick-role behavior compliance (P>0.05). Conclusion: There was a negative weak relationship between health locus of control and patient's sick role behavior compliance. Therefore further study to investigate the relating factor of the sick role behavior compliance among above of middle aged diabetes mellitus patients is necessary.

• 한국산학기술학회논문지
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• 제19권5호
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• pp.54-63
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• 2018

본 연구에서는 고속도로 도로부의 표준단면을 대상으로 패널식 보강토 옹벽의 높이별 안전율과 경제성에 대해 비교 검토하였다. 설계기준에 따라 하중조건은 고속도로의 단면 및 형상조건을 고려하여 콘크리트 포장의 사하중과 차량하중을 재하하고 최상단 보강재의 경우 방호벽의 충돌하중을 고려하였다. 보강재의 길이는 보강토 옹벽의 높이에 따라 0.9H로 배치하였기 때문에, 보강토체의 형상에 따라 지배되는 외적 안정성에 대해 높이의 증가에 따른 영향은 거의 없는 것으로 나타났다. 지지력에 대한 안전율은 보강토 옹벽의 높이에 따라 자중이 증가되기 때문에 급격히 감소되었다. 복합중력식 설계법에 따른 내적 안정성을 검토한 결과, 인발 안전율은 증가되고 파단 안전율은 감소되었다. 보강토 옹벽의 높이가 증가될수록 활동력으로 작용되는 수평토압과 저항력으로 작용되는 수직토압이 함께 증가되기 때문에 인발의 안전율은 증가되었다. 돌기형 강재 보강재의 장기 허용인장력은 상수이기 때문에, 높이에 따라 활동력에 대한 안전율은 수평토압이 증가되어 감소되었다. 블록식 보강토 옹벽보다는 패널식 보강토 옹벽의 경제성이 우수한 것으로 나타났고, 기존 옹벽과 비교하면 5.0 m이상의 높이에서 패널식 보강토 옹벽의 경제성이 가장 우수한 것으로 나타났다.

• 대한간호학회지
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• 제19권1호
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• pp.24-39
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• 1989

This study was conducted to investigate the present situation and problems related to the use of nursing diagnosis in practice. The data were obtained from 332 subjects (27 director of nursing service, 302 staff nurses) who worked in university hospitals in Korea from July through August 1988 using a mailed questionnaire. Data were analyzed by frequency, X$^2$ test and t-test. The findings were as follows ; 1, Clinical use of nursing diagnosis by directors of nursing service and staff nurses. 1) The majority of the nursing departments (88.9%) conducted group education on nursing diagnosis during the last 5 years and 81.5% of them kept a record format for nursing diagnosis : 88.9% of them had had prior experience with the nursing diagnosis. 2) Most of nurses (97.0%) had received education on nursing diagnosis. 2. Factors related to the clinical use of nursing diagnosis in nursing service departments and by staff nurses. 1) The one factor related to the use of nursing diagnosis in the nursing service department was the existence of a record. 2) Factors related to the use of nursing diagnosis by the staff nurses were the organization style of the nursing service department, group education during the last 5 years, existence of a record, the attitude of the director of nursing service, and prior experience of the use of the nursing diagnosis as characteristics of nursing service department and educational experience of nursing diagnosis as a character of nurse. 3. Problems with the use of nursing diagnosis. 1) The primary problem was the lack of time and personnel (mean : 3.757) ; the second problem was the lack of knowledge and will to use nursing diagnosis in practice by the staff nurses(mean : 3.546). 2) There was no significant difference in problems expressed by the director of nursing services and the nurses. The majority of nurses who worked in the university hospitals expressed interest in and concern about the use of nursing diagnosis. Most of the nurses had had education about on nursing diagnosis but use in practice was limited. The primary problem was lack of time and manpower. Strategies for improving use of the nursing diagnosis in practice : 1) Strengthening the education about nursing diagnosis and a holistic approach to understanding human beings. 2) Develop protocols for the use of nursing diagnosis. 3) Eliminate the language barrier regarding nursing diagnosis by translation into in Korean. 4) Decentralization of the nursing service to promote accountability by individual nurses for use of nursing diagnosis.

• Child Health Nursing Research
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• 제20권4호
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• pp.314-321
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• 2014

목적 본 연구는 사회인지진로이론에 입각하여 우리나라 고등학생의 정신 건강 및 문제행동에 영향을 미치는 요인을 규명하기 위해 수행되었다. 방법 본 연구는 2013년 11월 18일부터 29일까지, S시에 소재한 인문계 고등학교 재학생 384명(남자 186명, 여자 198명)을 대상으로 한 서술적 조사연구이다. 연구도구는 개인 배경 변인, 진로 관련 변인(진로장벽, 학습경험, 자기효능감, 결과기대, 진로미결정), 정신건강 및 문제행동에 관한 자기기입식 설문지였으며 수집된 자료는 SPSS 21.0 프로그램을 활용하여 기술통계, 상관관계 및 다중 회귀분석을 하였다. 결과 다중 회귀분석 결과, 개인적 변인으로 스트레스 인지(t=5.12, p < .001)와 평상시 건강상태(t=-4.08, p <.001), 배경적 변인으로 학업성적(t=5.46, p <.001), 진로 관련 변인에서 진로장벽(t=10.57, p <.001)이 정신 건강 및 문제행동에 유의미한 영향을 미치는 요인으로 나타났다. 결론 고등학생의 정신건강 및 문제행동의 영향요인으로 개인 배경 변인과 함께 진로장벽을 확인하였다. 특히, 진로결정은 발달과정 동안 지속적으로 영향을 받으므로 진로를 선택하는 청소년 후기에 이를 고려한 예방적, 중재적 접근이 필요하다. 본 연구결과를 토대로 청소년의 정신 건강 및 문제행동 수준을 개선하기 위한 중재 개발과 학교보건 및 실무에의 적용에 기초자료로 활용될 것을 기대한다.

• 벤처창업연구
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• 제4권1호
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• pp.89-111
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• 2009

점점 높아져 가는 프랜차이즈 사업에 대한 관심과 상반되게 프랜차이즈 사업에 관한 연구는 고객만족을 위한 연구와 단편적 운영 지침서들에 머무를 뿐 운영자 시각에서 성공요인을 분석하고, 창업단계 및 운영단계로 나눠 실증한 연구는 찾아보기 어렵다. 또한, 식품분야의 프랜차이즈 사업에 대한 연구가 주를 이루고 었어 식품과 비식품 프랜차이즈 사업에 영향을 미치는 요인에 관한 비교연구는 지금까지 제대로 이뤄져 오지 못했다. 이에 본 연구는 프랜차이즈 사업의 단계별 업종별 성과에 영향을 미치는 요인을 분석하고 이를 토대로 국내 프랜차이즈 사업을 준비하는 예비창업자들이 실천해야 할 성공전략을 제시하였다. 연구결과 창업단계의 성장요인으로 사업적성의 여부, 사업조직의 여부, 사업아이템의 적합성, 경쟁구도와 본사자문의 여부가 선별되었고, 운영단계의 성공요인으로는 슈퍼바이저의 능력, 본사와 가맹점의 마케팅 능력, 본사지원의 유무, 고객관리능력, 직원만족이 도출되었다.

• 대한수의학회지
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• 제51권3호
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• pp.217-225
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• 2011

Glatiramer acetate (GA; Copaxone) has been shown to be effective in preventing and suppressing experimental autoimmune encephalomyelitis (EAE), the animal model of multiple sclerosis (MS). It has been recently shown that GA-reactive T cells migrate through the blood-brain barrier, accumulate in the central nervous system (CNS), secrete antiinflammatory cytokines and suppress production of proinflammatory cytokines of EAE and MS. Development of EAE requires coordinated expression of a number of genes involved in the activation and effector functions of inflammatory cells. Activation of inflammatory cells is regulated at the transcriptional level by several families of transcription factors. One of these is the nuclear factor kappa B ($NF{\kappa}B$) family which is present in a variety of cell types and involved in the activation of immune-relative genes during inflammatory process. Since it is highly activated at site of inflammation, $NF{\kappa}B$ activation is also implicated in the pathogenesis of EAE. In this study, we examined whether the inhibition of $NF{\kappa}B$ activation induced by GA can have suppressive therapeutic effects in EAE mice. We observed the expression of $NF{\kappa}B$ and phospho-$I{\kappa}B$ proteins increased in GA-treated EAE mice compared to EAE control groups. The immunoreactivity in inflammatory cells and glial cells of $NF{\kappa}B$ and phospho-$I{\kappa}B$ significantly decreased at the GA-treated EAE mice. These results suggest that treatment of GA in EAE inhibits the activation of $NF{\kappa}B$ and phophorylation of $I{\kappa}B$ in the CNS. Subsequently, the inhibition of $NF{\kappa}B$ activation and $I{\kappa}B$ phosphorylation leads to the anti-inflammatory effects thereby to reduce the progression and severity of EAE.