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World Research Trends in Hormone Replacement Therapy (HRT) for Postmenopausal Women and Traditional Korean Medicine (TKM) Research Group's Response (폐경기 여성의 호르몬대체요법(HRT)과 관련된 국제적 연구경향과 한의학계의 대응에 관한 소고)

  • Kim Dong-Il
    • The Journal of Korean Medicine
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    • v.26 no.2 s.62
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    • pp.182-194
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    • 2005
  • Objectives: After the discontinuance of the Women's Health Initiative (WHI)clinical trial in the U.S. in July 2002, I thought that the domestic medical field would come to a crisis in hormonal treatment for perimenopausal and postmenopausal women. However, the domestic condition of HRT has barely changed. This study was designed to investigate world research trends in HRT and bring forward the response of the Traditional Korean Medicine (TKM) Research Group. Methods: I investigated recent domestic ;md world research trends about HRT and climacteric syndrome. Based on this analysis, I predicted western medical research trends and direction for HRT and medical care of perimenopausal and postmenopausal women. Results and Conclusions: I propose that we (TKM Research Group) have to explain the side effects of HRT for postmenopausal women and try to suggest complementary therapy for it. For that aim, the Association of Korean Medicine's effort is very important, as well as personal practitioner's actions.

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Evaluation of Bond Performance for AC overlay on PCC Pavement (AC / PCC 복합포장 경계면 재료의 부착 성능 평가)

  • Kim, Dong kyu;Hwang, Hyun sik;Christopher, Jabonero;Ryu, Sung woo;Cho, Yoon ho
    • International Journal of Highway Engineering
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    • v.18 no.5
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    • pp.1-9
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    • 2016
  • PURPOSES : This study focuses on the evaluation of interface performance with varying surface texture and tack coat application in an asphalt overlay. METHODS : The evaluation is carried out in two phases: tracking test and interface bond strength test. Using an image processing tool, tracking test is conducted to evaluate the susceptibility of the tack coat material to produce excessive tracking during application. Using the pull-off test method, the bond strength test is performed to determine the ability of the interface layer to resist failure. RESULTS : Results show that the underseal application yields less tracking compared to other applications. However, the bond strength is barely within the minimum acceptable value. On the other hand, RSC-4 produces higher bond strength for all surface types, but the drying time is long, which produces excessive tracking. CONCLUSIONS : While underseal application may be suitable for a trackless condition, the bond strength is less appealing compared to the rest of the tack applications available. RSC-4 demonstrated a high and consistent bond strength performance, but more time is required for drying to avoid excessive tracking. Tack coat application and surface type combination produce varying results. Therefore, these should be considered when selecting suitable future tack coat application options.

NDE of Low-Velocity Impact Damage in GFRP Using Infrared Thermography Techniques

  • Kim, Ghiseok;Lee, Kye-Sung;Hur, Hwan;Kim, Sun-Jin;Kim, Geon-Hee
    • Journal of the Korean Society for Nondestructive Testing
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    • v.35 no.3
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    • pp.206-214
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    • 2015
  • In this study, low-velocity impact damage (LVID) in glass fiber reinforced plastic (GFRP) was investigated using pulse thermography (PT) and lock-in thermography (LIT) techniques. The main objective of this study was to evaluate the detection performance of each technique for LVID in GFRP. Unidirectional and cross-ply GFRPs were prepared with four energy levels using a drop weight impact machine and they were inspected from the impact side, which may be common in actual service conditions. When the impacted side was used for both inspection and thermal loading, results showed that the suggested techniques were able to identify the LVID which is barely visible to the naked eye. However, they also include limitations that depend on the GFRP thickness at the location of the delamination produced by the lowest impact energy of five joule.

Acoustic Quality Of Taffy-seller Scissors Sound (엿장수 가위소리의 음향특성)

  • Jung, Chul-Woon;Kook, Jung-Hun;Jung, Eun-Jung;Kim, Jae-Soo
    • Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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    • 2007.05a
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    • pp.710-714
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    • 2007
  • The wheat-gluten vendor's Shears Sound which was ever able to hear barely at the conventional market place or some specific gala period is a familiar sound to us, also a delightful sound even without any reason. The blunt Shears Sound spreading faraway attracts the mind of hearer and it makes neighbors gathering. Nevertheless, it becomes to be left as being a forgotten sound little by little to our society that rapidly growing with high degree. In this Study, as for an acoustic analysis of the wheat-gluten Shears Sound, as being a forgotten our own sound, in order to examine the difference according to the character of various shears, after making 26 pieces of various Shears and we had ever measured, appraised on the sound pressure level by each wave-form and frequency of respective Shears Sounds at the semi-anechoic chamber, W University. At the study result, the acoustic character of wheat-gluten vendor's Shears Sound was able to be grasped, and we could find out 4 pieces of Shears which were judged as more superior in acoustic capability than the existing wheat-gluten Shears among the 26 pieces of various Shears.

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A New Species and a New Record of the Diastylidae (Crustacea: Cumacea) from Korea

  • Lee, Chang-Mok;Lee, Kyung-Sook
    • Animal Systematics, Evolution and Diversity
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    • v.28 no.2
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    • pp.71-83
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    • 2012
  • In this study, a new species, $Dimorphostylis$ $breviplicata$ n. sp. is described and illustrated on the basis of specimens collected from the shallow Korean waters. This new species is similar to $Dimorphostylis$ $brevicaudata$ (Zimmer, 1903), $Dimorphostylis$ $acroplicata$ Harada, 1960 and $Dimorphostylis$ $valida$ Gam$\hat{o}$, 1962 in that the carapace has three pairs of oblique ridges on the surface. However, the new species is distinguished by the combination of the following features: the middle oblique ridge is short and not joined to the other oblique ridges; the transverse ridge is absent on the frontal lobe; the dorso-median process on the pereonite 5 is only barely visible; the male telson has no short stout seta on the both lateral margins; the length ratio of the first to remaining articles combined on the male uropod is 1 : 0.7. A key to the Korean $Dimorphostylis$ species is provided. Also, $Diastylis$ $alaskensis$ Calman, 1912 is redescribed as a new recorded species of the Korean fauna.

Induction of intercellular chitinase isozymes in bean and soybean leaves under stress (강낭콩과 대두 잎에서 세포간액 키틴분해효소의 분포와 유도)

  • Park, Ro-Dong;Cho, Yu-Young;Jhon, Deok-Young
    • Applied Biological Chemistry
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    • v.37 no.4
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    • pp.255-258
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    • 1994
  • Using the enzyme activity staining, we studied the induction and distribution of chitinase isozymes, pathogenesis-related proteins, in intercellular fluids of bean and soybean leaves under stress conditions. The chitinase in intercellular fluids was barely detected in healthy plant leaves. By treatment of ethylene, pathogen (Fusarium oxysporum), or wounding, only 34 kD intercellular endochitinase was induced in bean leaves, while 30 kD and 36 kD intercellular endochitinases were induced in soybean leaves.

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Effect of centrifugation on tryptic protein digestion

  • Kim, Soohwan;Kim, Yeoseon;Lee, Dabin;Kim, Inyoung;Paek, Jihyun;Shin, Dongwon;Kim, Jeongkwon
    • Analytical Science and Technology
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    • v.30 no.2
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    • pp.96-101
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    • 2017
  • This study investigated the effect of centrifugation on tryptic digestion. This was done by applying different centrifugation speeds (6,000, 8,000, 10,000, 20,000, and $30,000{\times}g$) over various durations (0, 10, 20, 30, 40, 50, and 60 min) to digest two model proteins - cytochrome c and myoglobin. The intact proteins and resulting peptides were identified using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. Centrifugation greatly improved the tryptic digestion efficiency of cytochrome c, where either an increase in centrifugation speed or in digestion duration significantly improved the digestion of cytochrome c. However, centrifugation did not noticeably improve the digestion of myoglobin; 16 h of centrifuge-assisted tryptic digestion at $30,000{\times}g$ barely removed the myoglobin protein peak. Similar results were also obtained when using conventional tryptic digestion with gentle mixing. When acetonitrile (ACN) was added to make 10% ACN buffer solutions, the myoglobin protein peak disappeared after 6 h of digestion using both centrifuge-assisted and conventional tryptic digestions.

A Study on the Standby Power Characteristics of Sensor Luminaires (광원별 센서등기구의 대기전력 특성에 관한 연구)

  • Park, Chang-Yong;Seo, Jeong-Hyun
    • Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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    • v.28 no.10
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    • pp.9-15
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    • 2014
  • Standby power, so called an electric vampire, is a power which is consumed by appliances and office equipments connected to power sources while the devices are not performing. Sensor luminaires consist of PIR(Pyroelectric Infrared Ray) sensor, illuminance sensor(CdS), and light source. The sensor luminaires are one of the devices that consume a huge amount of standby power; it stands by for an average sum of 23 hours a day and performs only when moving subjects are detected under it, which barely takes up an hour per day. The purpose of this study is to provide basic materials to the selection of standby power items and to enable to explore a way to decrease the standby power by measuring and analyzing the power consumption of sensor luminaires. According to the results, the average standby power of LED sensor luminaires is 1.1W which is significantly higher than other products, and decrease in the standby power consumption of SMPS is important through the measurement.

Effects of prestressing force on natural frequency of prestressed concrete beams considering self-weight

  • Shin, Soobong;Lee, Hokyoung;Lee, Jong-Han
    • Structural Engineering and Mechanics
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    • v.74 no.4
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    • pp.495-502
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    • 2020
  • This study investigated the effects of prestressing force on the natural frequency of concrete beams considering changes in the self-weight of the beam. For this, a finite element formulation was derived to account for the increase in the stiffness of a beam-tendon system due to the axial force and deformation induced by prestressing of the tendon. The developed finite element formulation was validated with the data obtained in laboratory experiments. The experimental natural frequencies of the small prestressed concrete (PSC) beam specimens were consistent with those obtained using the proposed method. The first natural frequency increased almost linearly as the prestressing force increased. The proposed method was then applied to four actual PSC bridges typically employed in the field. Different from the laboratory specimens, the first natural frequencies of the actual PSC bridges barely changed or increased with increasing prestressing force. The results of an analytical parametric study showed that the increase in the natural frequency strongly depended on the magnitude of the prestressing force relative to the total weight of the structure. Thus, the variation in the natural frequencies of the actual PSC bridges with high total weight relative to the prestressing force was negligible due to the application of the prestressing force.

Molecular Characterization of a ${\beta}$-1,4-Endoglucanase Gene from Bacillus subtilis H12

  • Oh, Jin-Hwan;Cha, Jeong-Ah;Yoon, Min-Ho
    • Applied Biological Chemistry
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    • v.51 no.4
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    • pp.299-304
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    • 2008
  • A ${\beta}$-1,4-endoglucanase gene from Bacillus subtilis H12 was cloned into Escherichia coli JM109 (pBC8) and sequenced. The endoglucanase gene with an insert DNA of 2.5 kb possessed an open reading frame of 1,500 bp encoding a mature protein of 499 amino acids with a calculated molecular mass of 55 kDa. The deduced amino acid sequence showed similarity to those of the known neutral cellulase genes of B. subtilis PAP115 (99.2%) and BSE616 (97.8%), as well as the alkaline gene of Bacillus sp. N4 (55.1%). The endoglucanase activity expressed by E. coli (pBC8) was localized in the periplasmic fraction (80%) and the cytoplasmic fraction (20%). An endoglucanase was purified from the periplasmic fraction by performing gel filtration and anion exchange chromatography. The molecular weight of the purified enzyme was estimated to be 31 kDa by SDS-PAGE, and the maximum activity occurred at pH 7 and $40^{\circ}C$. The enzyme easily hydrolyzed soluble substrates such as carboxymethyl cellulose and barely ${\beta}$-glucan, whereas the sigmacell and xylan, the known insoluble substrates, were not entirely hydrolyzed.