• 지역과문화
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• v.6 no.4
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• pp.47-72
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• 2019

The purpose of this paper is to explore what roles can and should regional culture play in establishing a regional innovation system, which has been recently described as an essential factor for balanced regional development and specialized regional development. In doing so, we first investigated key concepts and discourses regarding regional innovation system and examined the success factors of a regional innovation system. We also explored how the Korean policy makers have developed the nation's regional innovation policy and regional cultural policy in order to understand the policy context and its limitations. After examining the theoretical background, we reviewed the representative cases of regional innovation in Japan, Yufuin and Yubari, to grasp the way in which 'culture' plays its roles in the formation of the regional innovation system. Since culture has a role as a unique sector, such as art and content industry, as well as a community's style of life, this study tried to explore the aspects and ways of how culture can contribute to the establishment of regional innovation systems considering these distinctive levels. In drawing the implications of the case study, we found that special attention is required for the 'process of formation' of regional innovation systems. We also confirmed that the success of the core activities at each stage heavily relies on the culture of the region; in order to fully understand the relations, it is necessary to re-establish the existing concept of culture and cultural policy with a more holistic perspective.

• KIPS Transactions on Software and Data Engineering
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• v.2 no.1
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• pp.27-34
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• 2013

Background subtraction is one of the key techniques for automatic video content analysis, especially in the tasks of visual detection and tracking of moving object. In this paper, we present a new sample-based technique for background extraction that provides background image as well as background model. To handle both high-frequency and low-frequency events at the same time, multiple interval background models are adopted. The main innovation concerns the use of a confidence factor to select the best model from the multiple interval background models. To our knowledge, it is the first time that a confidence factor is used for merging several background models in the field of background extraction. Experimental results revealed that our approach based on multiple interval sampling works well in complicated situations containing various speed moving objects with environmental changes.

• Journal of Digital Convergence
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• v.16 no.9
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• pp.51-61
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• 2018

This The purpose of this study is to propose a Technology Transfer Commercialization Model(TTC Model) that reflects the domestic background of R&D, technology transfer and its commercialization. This study outlines the existing technology commercialization model, examines the background of domestic technology transfer, presents TTC Model, and introduces the application of this model. As a result of this study, the TTC Model suggested the role of each participant in each stage and divided into the provider-led domain and the consumer-led domain. The use of this model can be applied to a technology provider in a way that progressively reduces its role. In the case of technology users, it can be used a corporate innovation model that gradually expands leading to commercialization and profit realization. This study is meaningful in that it clarifies the roles and the level of leadership of technology transfer entities.

• Management & Information Systems Review
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• v.29 no.4
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• pp.225-244
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• 2010

In the information society, characterized by knowledge and network economy, standards and standardization became a very important factor in determining the competitiveness of nations and firms. This paper defines the concept of standards and standardization and reconstructs the theory on the relationship between standards and technological innovation. The findings and policy implications are as follows. First, the effect of standards on technological innovation differs according to its function(compatibility, minimum quality, information, and variety reduction) and types(product-related and non-product). On the other hand, standards can impede technological innovation. Second, in terms of national innovation system(NIS), standards are an infra-technology, which is a public good. Therefore, government should decide the optimal level of investment on standards and standardization. Third, since standards foster firms' innovation over the all stages of business activities company, industry, and government should connect standardization activities with R&D, manufacturing, marketing, supply chain, and technology transfer, Fourth, standards play an important role in product innovation as well as process innovation. Based on these theoretical background and hypotheses, the empirical study of the Korean firms is needed.

• Journal of Technology Innovation
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• v.28 no.4
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• pp.151-163
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• 2020

The routinized tasks in the post-COVID era are to be replaced by digital technologies, while there is a high possibility that digital transformation technologies and non-routinized tasks have strong complementarity. In particular, looking at the job composition within Korea's industries, the intensities of routinized works appear to be continuously rising. It suggests that the potential side effects on the labor market caused by the acceleration of digital transformation in the post-COVID era will be greater within Korean innovation system. With this background, this study aims to provide a conceptual framework for dealing with potential crises such as, job polarization and widening gaps between workers in terms of economic earnings, based on an in-depth understanding of the inherent properties of digital transformation that will lead to structural changes in our economic and social system. In particular, focusing on the interaction between digital transformation technology and learning in the post-COVID era, this study attempts to redefine the role of the innovation policy for making a successful transition to a new equilibrium state. In addition, this study examines the institutional conditions of the Korean innovation system which affect the creative learning activities of economic actors to draw policy implications for establishing future-oriented innovation policy. Based on these approaches, this study highlights the importance of coevolution between the skills demand and skills supply to spur inclusiveness of Korean innovation system in the post-COVID era.

• Journal of Dental Anesthesia and Pain Medicine
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• v.16 no.4
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• pp.303-307
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• 2016

Background: In dental intravenous sedation, continuous intravenous infusion of a low-dose drug requires an infusion pump such as a syringe pump. To develop a new syringe pump for clinical use, the functions of the pump must meet certain international standards. Various safety and efficacy tests must be performed on the syringe pump, as stipulated by these standards, and an approval must be received from the approving agency based on such test results. Methods: The authors of the present study developed a novel syringe pump and performed efficacy evaluation by testing its infusion speed at 1 and 25 ml/h, and infusion performance testing at 2 and 24 h. Moreover, performance evaluation was conducted by comparing the novel pump to an existing pump with the infusion speed varied from 1 to 5 ml/h. Results: In the efficacy testing on the newly developed syringe pump, infusion with the infusion speed initially set to 1 ml/h resulted in infusion speeds of 1.00 and 0.99 ml/h in the 2- and 24-h assessment, respectively. Changing the infusion speed setting to 25 ml/h resulted in an infusion speed of 25.09 and 23.92 ml/h in the 2- and 24-h assessment, respectively. These results show no significant differences when compared with other commercially available pumps. Conclusions: The efficacy testing of the newly developed syringe pump showed the accuracy to be within tolerance. Based on these findings, we believe that the newly developed syringe pump is suitable for clinical use.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.9
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• pp.3703-3708
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• 2015

Background: The neutrophil-to-lymphocyte ratio (NLR) is a strong predictor of mortality in patients with colorectal, lung, gastric cancer, pancreatic and metastatic renal cell carcinoma. We here evaluated whether preoperative NLR is an independent prognostic factor for non-metastatic renal cell carcinoma (RCC). Materials and Methods: Data from 327 patients who underwent curative or palliative nephrectomy were evaluated retrospectively. In preoperative blood routine examination, neutrophils and lymphocytes were obtained. The predictive value of NLR for non-metastatic RCC was analyzed. Results: The NLR of 327 patients was $2.72{\pm}2.25$. NLR <1.7 and NLR ${\geq}1.7$ were classified as low and high NLR groups, respectively. Chi-square test showed that the preoperative NLR was significantly correlated with the tumor size (P=0.025), but not with the histological subtype (P=0.095)and the pT stage (P=0.283). Overall survival (OS) and disease-free survival (DFS) were assessed using the Kaplan-Meier method. Effects of NLR on OS (P=0.007) and DFS (P=0.011) were significant. To evaluate the independent prognostic significance of NLR, multivariate COX regression models were applied and identified increased NLR as an independent prognostic factor for OS (P=0.015), and DFS (P=0.019). Conclusions: Regarding patient survival, an increased NLR represented an independent risk factor, which might reflect a higher risk for severe cardiovascular and other comorbidities. An elevated blood NLR may be a biomarker of poor OS and DFS in patients with non-metastatic RCC.

• Journal of the Korea Convergence Society
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• v.8 no.7
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• pp.159-166
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• 2017

A 'wicked problem' is something that is hard to notice and not easy to perceive. This study focuses on understanding the precise concept of wicked problem through studying the background that led to the introduction of the term wicked problem. On the other hand, for social innovation, which has recently become a hot topic, it is necessary to identify wicked problem. Social innovation means solving in an innovative way that is more effective, efficient and sustainable than existing ones. As the beneficiary is not an individual but a society, it is in line with the field covered by wicked problem. Therefore, the study introduces a case in which wicked problems are solved through novel ways, that is, design thinking. Through the case study, it was confirmed that design thinking helps identifying problems that are not revealed and contributes to social innovation. As a result, we hope that this research will contribute to help solve the problems that we need to resolve in our society by using design thinking.

• The Journal of the Korea Contents Association
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• v.19 no.5
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• pp.128-137
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• 2019

This study typified and analyzed local governments' innovation policy through brand task and provided policy implications. A total of 844 local governments' brand task were used to classify the policy fields of the brand task by eight types of local governments. The main analysis results are summarized as follows. First, the ratio of social economy/local economy was the highest in all local government. Second, there is a difference in the policy fields that are focused by local governments. Third, the selection of innovation policy reflects the specificity of the region. Fourth, local government focusing on the type of brand task were differentiated. Therefore, these results confirm the theoretical relevance of the typology of local government suggested in the theoretical background. Policy implications are as follows: the necessity of innovation policy for revitalization of local economy, establishment of innovation policy in accordance with local characteristics, and propagation of excellent innovation policy.

• Nutrition Research and Practice
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• v.16 no.3
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• pp.298-313
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• 2022

BACKGROUND/OBJECTIVES: The effectiveness of natural compounds in improving athletic ability has attracted attention in both sports and research. Gynostemma pentaphyllum (Thunb.) leaves are used to make traditional herbal medicines in Asia. The active components of G. pentaphyllum, dammarane saponins, or gypenosides, possess a range of biological activities. On the other hand, the anti-fatigue effects from G. pentaphyllum extract (GPE) and its effective compound, gypenoside L (GL), remain to be determined. MATERIALS/METHODS: This study examined the effects of GPE on fatigue and exercise performance in ICR mice. GPE was administered orally to mice for 6 weeks, with or without treadmill training. The biochemical analysis in serum, glycogen content, mRNA, and protein expressions of the liver and muscle were analyzed. RESULTS: The ExGPE (exercise with 300 mg/kg body weight/day of GPE) mice decreased the fat mass percentage significantly compared to the ExC mice, while the ExGPE showed the greatest lean mass percentage compared to the ExC group. The administration of GPE improved the exercise endurance and capacity in treadmill-trained mice, increased glucose and triglycerides, and decreased the serum creatine kinase and lactate levels after intensive exercise. The muscle glycogen levels were higher in the ExGPE group than the ExC group. GPE increased the level of mitochondrial biogenesis by enhancing the phosphorylation of peroxisome proliferator-activated receptor-γ coactivator-1α (PGC-1α) protein and the mRNA expression of nuclear respiratory factor 1, mitochondrial DNA, peroxisome proliferator-activated receptor-δ, superoxide dismutase 2, and by decreasing the lactate dehydrogenase B level in the soleus muscle (SOL). GPE also improved PGC-1α activation in the SOL significantly through AMPK/p38 phosphorylation. CONCLUSIONS: These results showed that GPE supplementation enhances exercise performance and has anti-fatigue activity. In addition, the underlying molecular mechanism was elucidated. Therefore, GPE is a promising candidate for developing functional foods and enhancing the exercise capacity and anti-fatigue activity.