• 한국기술혁신학회:학술대회논문집
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• 한국기술혁신학회 2005년도 춘계학술대회
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• pp.95-110
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• 2005

Science & Technology(S&T) is the most important thing to attain competitiveness in the 21st century, Our traditional S&T policies have been focused on hardware infra structure. we should consider software of S&T to enhance effectiveness. S&T should be had a correct understanding method of the creation for S&T culture. It implies that S&T policy in the 21st century should consider nonmaterial factors which include social, human, environmental and culture. Under this background, The purpose of this paper is to seek new S&T policy in the 21st century. Therefor this paper deals with how we can prepare for the future S&T policy and classify the change of S&T policy of Korea and analyze the characteristic of each phase. This paper argues that all actors (for example, S&T personnel, corporate using S&T, general public) should participate in the process of S&T innovation since the 21st century is the generation of the general public S&T. Also this paper presented the expanded S&T policy Right S&T policy could leads to diffuse right S&T culture. Diffusing S&T culture could accomplish expanded S&T policy which was considered phases of culture and welfare.

• 산업경영시스템학회지
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• 제36권3호
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• pp.109-117
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• 2013

This study designed a "Diagnostic Model for Management Innovation of Medium Enterprises" based on the theoretical background of success factor and management diagnosis model for management innovation of medium enterprises and suggested a measure for utilization of strategic subject and diagnostic model that enterprises can apply. Utilization of medium enterprises management innovation diagnostic model designed through this study would be of help for making a diagnosis of the capability maturity level of enterprises' current management system and improving it by establishing a challenging capability objective and building a circulation system capable of innovating enterprises. It is expected for enterprises to overcome growing pains and establish a management system capable of achieving outcome (productivity) by repeating measurement and innovation through management diagnosis. In addition, this study provides a method to produce a strategic subject, select priority of implementation and prepare an implementation road map by classifying and filtering management issues produced as a result of management diagnosis in a systematic way. If variables necessary for production of an objective weighted value of scoring and discover of elements for category of diagnostic model and elementary items as well as design of a self-diagnosis questionnaire, measurement of management outcome suggested in this study can be able to be verified and supplemented through case study in the future, it is expected to make the degree of completion as a diagnostic model elevated that may help for growth and development through innovation of medium enterprises.

• 한국경제지리학회지
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• 제22권3호
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• pp.321-336
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• 2019

ICT 산업이 국가경쟁력 성장에 일조하는 산업으로 발전하게 되면서 정부 지원을 통해 서울시 강남구 테헤란로 지역이 ICT 산업을 기반으로 활성화되었다. 본 연구는 벤처와 ICT 기업들의 밀집지역으로서 이들 발전에 핵심지역인 강남구 테헤란밸리를 살펴보고자 한다. 특히 테헤란밸리는 계획적으로 조성된 산업단지의 등장 등과 같은 주변 입지 변화로 잠시 쇠퇴하는 모습이 나타났지만 혁신에 앞장서는 스타트업을 위한 지역으로 재도약 하며 새로운 혁신지구의 모습을 나타내고 있는 것으로 보여진다. 따라서 본 연구에서는 강남구 테헤란밸리를 대상으로 대도시 내 새로운 도시형 혁신지구가 등장한 배경과 형성요인을 살펴보았다. 또한 대도시 혁신지구의 지표를 경제적/공간적 물리적/네트워크/인적 자산으로 구분하였고, 이를 바탕으로 대도시 내 새로운 도시형 혁신지구로서 테헤란밸리의 위상을 살펴보았다. 더불어 스타트업과 이를 지원하는 기관들, ICT 기술 기반의 혁신주도 기업과 구성원이 집적된 도시의 혁신 지구적 특성을 살펴보고 이를 통해 지역경제 발전을 위한 시사점을 도출하였다.

• Journal of Ginseng Research
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• 제47권1호
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• pp.89-96
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• 2023

Background and aim: Panax ginseng, a key herbal medicine of replenishing Qi and tonifying Spleen, is widely used in the treatment of gastrointestinal diseases in East Asia. In this study, we aim to investigate the potential effects and mechanisms of polysaccharides from P. ginseng (PGP) on intestinal mucosal restitution which is one of the crucial repair modalities during the recovery of mucosal injury controlled by the Ca²⁺ signaling. Methods: Rat model of intestinal mucosal injury was induced by indomethacin. The fractional cell migration was carried out by immunohistochemistry staining with BrdU. The morphological observations on intestinal mucosal injury were also performed. Intestinal epithelial cell (IEC-6) migration in vitro was conducted by scratch method. Western-blot was adopted to determine the expressions of PLC-𝛾1, Rac1, TRPC1, RhoA and Cav-1. Immunoprecipitation was used to evaluate the levels of Rac1/PLC-𝛾1, RhoA/TRPC1 and Cav-1/TRPC1. Results: The results showed that PGP effectively reduced the assessment of intestinal mucosal injury, reversed the inhibition of epithelial cell migration induced by Indomethacin, and increased the level of Ca²⁺ in intestinal mucosa in vivo. Moreover, PGP dramatically promoted IEC-6 cell migration, the expression of Ca²⁺ regulators (PLC-𝛾1, Rac1, TRPC1, Cav-1 and RhoA) as well as protein complexes (Rac1/PLC-𝛾1, Cav-1/TRPC1 and RhoA/TRPC1) in vitro. Conclusion: PGP increases the Ca²⁺ content in intestinal mucosa partly through controlling the regulators of Ca²⁺ mobilization, subsequently promotes intestinal epithelial cell migration, and then prevents intestinal mucosal injury induced by indomethacin.

• Journal of Ginseng Research
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• 제47권3호
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• pp.440-447
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• 2023

Background: The human hair follicle undergoes cyclic phases-anagen, catagen, and telogen-throughout its lifetime. This cyclic transition has been studied as a target for treating hair loss. Recently, correlation between the inhibition of autophagy and acceleration of the catagen phase in human hair follicles was investigated. However, the role of autophagy in human dermal papilla cells (hDPCs), which is involved in the development and growth of hair follicles, is not known. We hypothesized that acceleration of hair catagen phase upon inhibition of autophagy is due to the downregulation of Wnt/β-catenin signaling in hDPCs, and that components of Panax ginseng extract can increase the autophagic flux in hDPCs. Methods: We generated an autophagy-inhibited condition using 3-methyladenine (3-MA), a specific autophagy inhibitor, and investigated the regulation of Wnt/β-catenin signaling using the luciferase reporter assay, qRT-PCR, and western blot analysis. In addition, cells were cotreated with ginsenoside Re and 3-MA and their roles in inhibiting autophagosome formation were investigated. Results: We found that the unstimulated anagen phase dermal papilla region expressed the autophagy marker, LC3. Transcription of Wnt-related genes and nuclear translocation of β-catenin were reduced after treatment of hDPCs with 3-MA. In addition, treatment with the combination of ginsenoside Re and 3-MA changed the Wnt activity and hair cycle by restoring autophagy. Conclusions: Our results suggest that autophagy inhibition in hDPCs accelerates the catagen phase by downregulating Wnt/β-catenin signaling. Furthermore, ginsenoside Re, which increased autophagy in hDPCs, could be useful for reducing hair loss caused by abnormal inhibition of autophagy.

• 기술혁신연구
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• 제29권1호
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• pp.1-38
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• 2021

본 논문에서는 에너지 섹터의 혁신성 제고를 위한 리빙랩(Living Labs) 활용 전략 수립에 관한 탐색적 분석 연구를 수행하였다. 기존 연구문헌을 통해 이론적 배경이 되는 리빙랩의 개념, 필수 구성요소, 혁신성 특성과 에너지 섹터의 혁신 이슈 유형을 확인할 수 있었다. 이를 토대로 리빙랩 필수 구성요소의 맞춤형 전략 수립과 혁신성 제고와의 연관성, 에너지 섹터에서의 혁신 이슈에 대한 접근으로 리빙랩 활용 가능성에 대해 에너지 리빙랩 사례 연구(해외 8건, 국내 1건)을 통해 분석되었다. 연구 결과, 리빙랩 필수 구성요소의 맞춤형 전략 수립이 혁신성 제고에 동인으로 작용 될 수 있으며, 리빙랩이 에너지 섹터의 혁신 이슈(수요관리, 공급기술, 기술사업화 촉진 및 수용성, 기술정책)에 대한 접근 방법론으로 효과적으로 활용 될 수 있음을 확인되었다. 사례연구 결과 기반으로 혁신성 기여 관점에서 리빙랩 사례별 동인을 도출하고 에너지 혁신이슈별 리빙랩 활용 전략을 수립하였다. 본 연구는 에너지 섹터에서의 혁신이슈에 대한 접근으로 리빙랩 모델의 활용 전략과 그 가치에 대한 탐색적, 기술적 분석 연구로서 종래에 시도되지 않았던 리빙랩 활용 전략 프레임워크를 제공할 수 있고, 에너지 리빙랩 활성화와 네트워크 형성에도 기여될 수 있다는 점에서 학술적·실용적·정책적 함의가 있다고 볼 수 있다.

• 한국IT서비스학회지
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• 제14권2호
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• pp.231-251
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• 2015

User Experience (UX) and Experience Innovation have been emphasized in the process of New Product Development (NPD). However, previous works which were conducted within the theme of UX mostly focused on the fragmentary aspects of user's experience in a specific usage-context only. For this reason, it is always hard to deal with questions on how to define the abstract concept of UX and how to apply this important keyword in actually NPD process both for satisfying potential users and for setting a market strategy. To address this issue, we focused on the fact that UX has an aspect of composition like pattern and structure. It means that we can understand the context of UX with clarifying characteristics of relations between user and experiential objects. Also, we referred to two sub-concepts of Complexity, Density and Centrality, as representative characteristics of relations in usage-context. Based on this theoretical background, we attempted to find UX design principles and concepts for NPD from the actual example cases of products and services in the real market. From these whole study process, we expect that our findings could have implications for academic and practical areas within the theme of Human-Centered Innovation.

• Asian Journal of Innovation and Policy
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• 제1권1호
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• pp.1-30
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• 2012

The status and functioning of Indian universities is explored in the Indian context from an NSI perspective. Whilst NSI is the main guiding post, the very social and economic context of Indian situation reflect the theoretical underpinning of this paper. The First part serves as a background to knowledge institutions and university sector in India. Basically, it identifies the main actors and agencies of India's NSI, namely, public research system comprising national laboratories, main science and technology agencies and councils and the university system. Given the focus of the paper on Indian universities in a macro historical perspective, the Second part is devoted to trace the growth and structure of university sector in terms of three phases, namely, 1940s to 1980; 1980 to 1990; and the era of liberalization after 1991. The Third part of the paper is devoted to knowledge production and knowledge diffusion. There are some important findings coming out of the quantitative data. It is argued that Indian production of doctorates is falling behind countries like China. Further, Indian universities are yet to achieve Humboltian goal. Finally, the paper has a concluding section which concerns with the current and future challenges facing Indian universities and their role in India's NIS.

• 동아시아경상학회지
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• 제9권4호
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• pp.103-111
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• 2021

Purpose - We attempt to provide a background, a review of current development of the digital technologies and their effect on the digital transformation process, and then offer our recommendations for identifying and taking strategic actions to exploit them. More importantly, we also aim to offer important recommendations for policymakers and practitioners how to better advance the innovation system by facilitating the development of digital technologies and take advantage of improvements in digital technologies. Research design, data, and methodology - This study undertakes an extensive and critical review of the digital transformation literature and identifies several important issues with relevant practical examples of best practices in the transition to digital transformation process. Results - This paper finds that digital technologies with strong technological backing have brought technological spillovers to the economy while also generating shocks. Conclusion - To maintain a healthy and developing market order, it is necessary for governments to innovate regulatory models. This study offers several important suggestions for government regulatory innovation that we believe should help to better deploy digital transformation initiatives and enhance the efficiency and effectiveness of government regulation in contributing more to the high-quality and healthy development of the digital economy.

• The Journal of Asian Finance, Economics and Business
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• 제8권3호
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• pp.683-693
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• 2021

Shipping has become an important sector in supporting social, economic, government, defense, security, cultural and other sectors to unite separate islands and broad seas. Thus, ports automatically become an important facility in Indonesia. The purpose of this research is to test and explain the effect of Organizational readiness for change, Service Innovation, and Corporate Image on Perceived opportunity and challenge. The research model with inferential analysis uses Structural Equation Modeling (SEM) analysis with the WarpPLS approach, expected to answer the statements of problem and be able to test the desired hypothesis. The model development in this research was based on the background, statements of problem, conceptual framework and research hypotheses. The model referred to is "Complete and Comprehensive Port." Its development was carried out through studying and synthesizing various sources. The most important source is the results of literature review in the form of theoretical developments and research results, then continued with compilation. The use of Organizational Change Readiness, Service Innovation, and Corporate Image in improving Port Competitiveness is seen as one of the novelties of this research, specifically the use of the Organizational Change Readiness variable which is often used in high-flexibility companies but now used in port companies as well.