• 보건교육건강증진학회지
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• 제12권2호
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• pp.146-161
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• 1995

This study is an effort to bring our attention to social dependence on alcohol, focusing on previous studies of drinking behaviors. Although drinking behavior and problems must be understood in a biopsychosocial framework, a certain aspect is often ignored in alcohol research. A few attention has been paid to social aspect of alcohol abuse or dependence. Social processes of drinking behavior deserve to have same attention as other aspects, psychological and physical aspects of the behavior. Literature show that the interdependence among group members exists to regulate individual's drinking behavior. Such social interactions tend to control drinking level for individual in terms of amounts, frequency, and preference. The drinking level tends to be dependent on desires for heavy drinkers, ignoring variabilities of individual's sensitivity to alcohol. However, such a heavy-oriented tendency in drinking behavior may have different patterns which are function of normative orientation of alcohol. negotiation among group members, and ethnoreligious characteristics. Perspectives from conflict tradition and symbolic interactionism are welcomed to illuminate multi-dimentional aspects of social dependence. Policy implication were discussed from public health perspective.

• Clinical and Experimental Pediatrics
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• 제51권9호
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• pp.935-943
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• 2008

Attention deficit hyperactivity disorder (ADHD) is a neurobehavioral developmental disorder characterized by a persistent pattern of inattention and/or hyperactivity, as well as forgetfulness, poor impulse control or impulsivity, and distractibility. The recommended evaluation includes documenting the type and severity of ADHD symptoms, verifying the presence of normal vision and hearing, screening for comorbid psychological conditions, reviewing the child's developmental history and school performance, and applying objective measures of cognitive function. Prevailing opinion characterizes ADHD as a disorder of executive function attributable to abnormal dopamine transmission in the frontal lobes and frontostriatal circuitry. A clearly defined etiology remains unknown, but studies suggest a strong genetic link. The aim of treatment is to decrease symptoms, enhance functionality, and improve well-being for the child and his or her close contacts. Stimulants remain the pharmacological agents of first choice for the management of ADHD, and psychosocial, behavioral and educational strategies that enhance specific behaviors may improve educational and social functioning in children with ADHD.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제15권6호
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• pp.2115-2127
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• 2021

Although significant progress has been made in synthesizing visually realistic face images by Generative Adversarial Networks (GANs), there still lacks effective approaches to provide fine-grained control over the generation process for semantic facial attribute editing. In this work, we propose a novel cross channel self-attention based generative adversarial network (CCA-GAN), which weights the importance of multiple channels of features and archives pixel-level feature alignment and conversion, to reduce the impact on irrelevant attributes while editing the target attributes. Evaluation results show that CCA-GAN outperforms state-of-the-art models on the CelebA dataset, reducing Fréchet Inception Distance (FID) and Kernel Inception Distance (KID) by 15~28% and 25~100%, respectively. Furthermore, visualization of generated samples confirms the effect of disentanglement of the proposed model.

• 국제물리치료학회지
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• 제10권2호
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• pp.1768-1773
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• 2019

Background: Aging reduces cognitive abilities, including visual memory (VM) and visual discrimination (VD). Since common cortical networks subserve eye movement and attention, voluntary eye movement may improve visual attention. Visual selective attention was major role for memory, and visual memory and visual attention are intimately related. Objective: To identify the improvement in VD and VM, after implementing the eye movement program consisting of saccadic eye movement (SEM) and pursuit eye movement (PEM) in the institutionalized healthy elderly. Design: Randomized controlled trial. Methods: The study involved a sample of 36 participants, and the mean age was 79.03 years (range 76~84 years). They were randomly allocated to the experimental group (n=16) and control group (n=20). Participants in the experimental group performed SEM 5 times per week for 4 weeks: twice daily at the same time in the morning and afternoon. The program was carried out for 3 minutes, and it consisted of SEM and PEM. The target's moving frequency was set at 0.5 Hz. VM and VD at the baseline and post-intervention were measured using Motor-Free Visual Perception test-4 (MFVPT-4). Results: VM significantly improved in the experimental group (p < .01), and significant differences were observed compared to the control group (p < .01). There was no significant change in VD. Conclusion: The eye movement program consisting of SEM and PEM increased VM more than VD. Therefore, eye movement program was feasible interventions for improving VM in institutionalized elderly persons.

• 수면정신생리
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• 제5권2호
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• pp.119-133
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• 1998

Attentional processes facilitate cognitive and behavioral performance in several ways. Attention serves to reduce the amount of information to receive. Attention enables humans to direct themselves to appropriate aspects of external environmental events and internal operations. Attention facilitates the selection of salient information and the allocation of cognitive processing appropriate to that information. Attention is not a unitary process that can be localized to a single neuroanatomical region. Before the cortical registration of sensory information, activation of important subcortical structures occurs, which is called as an orienting response. Once sensory information reaches the sensory cortex, a large number of perceptual processes occur, which provide various levels of perceptual resolution of the critical features of the stimuli. After this preattentional processing, information is integrated within higher cortical(heteromodal) systems in inferior parietal and temporal lobes. At this stage, the processing characteristics can be modified, and the biases of the system have a direct impact on attentional selection. Information flow has been traced through sensory analysis to a processing stage that enables the new information to be focused and modified in relation to preexisting biases. The limbic and paralimbic system play significant roles in modulating attentional response. It is labeled with affective salience and is integrated according to ongoing pressures from the motivational drive system of the hypothalamus. The salience of information greatly influences the allocation of attention. The frontal lobe operate response selection system with a reciprocal interaction with both the attention system of the parietal lobe and the limbic system. In this attentional process, the search with the spatial field is organized and a sequence of attentional responses is generated. Affective, motivational and appectitive impulses from limbic system and hypothalamus trigger response intention, preparation, planning, initiation and control of frontal lobe on this process. The reticular system, which produces ascending activation, catalyzes the overall system and increases attentional capacity. Also additional energetic pressures are created by the hypothalamus. As psychophysiological measurement, skin conductance, pupil diameter, muscle tension, heart rate, alpha wave of EEG can be used. Event related potentials also provide physiological evidence of attention during information process. NI component appears to be an electrophysiological index of selective attention. P3 response is developed during the attention related to stimulus discrimination, evaluation and response.

• 핵의학기술
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• 제26권2호
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• pp.43-47
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• 2022

핵의학 검체검사는 검사 결과의 품질 보증을 위해 내부정도관리 시스템을 체계화하여 질 관리를 시행하고 있다. 본 연구는 검사실 자체적인 허용 범위의 설정 시 참고가 될 수 있도록 여러 기관의 종목별 내부정도관리 및 외부정도관리의 변동계수 평균을 산출하여 종목별 질 관리 현황을 제공함으로써 핵의학 검체검사 결과의 품질 보증에 기여하고 체계적인 질 관리를 수행하고자 한다. 2020년 10월에서 2021년 12월까지 각 기관에서 시행한 42종목에 대한 내부정도관리 변동계수의 평균 및 10.0% 이상 이탈률을 구하였다. CV% 성적에 따라 상위 그룹(5.0% 이하), 중위 그룹(5.0~10.0%), 하위 그룹(10.0% 이상)으로 구분하여 비교하였고, 10.0% 이상 이탈률은 5개 이상 기관의 종목에 대해서 종양 표지자, 갑상선 호르몬, 기타 호르몬으로 분류하여 비교하였다. 2021년 1분기에서 4분기까지 28종목에 대해 외부정도관리 결과의 전체 평균 및 표준편차로 변동계수의 평균을 구하였다. 또한 2021년 상반기, 하반기 13종목에 대해 기관 간 숙련도 결과의 전체 평균 및 표준편차로 변동계수의 평균을 구하였다. 종목별로 내부정도관리 및 외부정도관리의 변동계수 평균을 비교하여 질 관리가 잘 이루어지는 종목과 관리에 주의가 필요한 종목을 비교 분석하였다. 6개 기관의 42종목에 대해 내부정도관리 변동계수의 평균을 산출한 결과 상위 그룹에 속하는 종목(5.0% 이하)은 ferritin, HGH, SHBG, 25-OH-VitD이며, 하위 그룹(10.0% 이상)은 cortisol, ATA, AMA, renin, estradiol이었다. 5개 이상 기관의 종양 표지자 8종목에 대해 변동계수의 10.0% 이상 이탈률은 CA-125와 CA-19-9가 우수한 성적을 나타내었으나, SCC-Ag와 CA-15-3 검사는 관리에 주의가 필요한 종목에 속했다. 갑상선 호르몬 7종목에 대해 변동계수의 10.0% 이상 이탈률을 비교한 결과 free T4와 T3 검사는 우수하였지만 AMA와 ATA는 관리에 주의가 필요해 보였다. 기타 호르몬 11종목에 대해 변동계수의 10.0% 이상 이탈률을 비교하였을 때 IGF-1, FSH, prolactin은 우수한 성적을 나타내었지만, estradiol, testosterone, cortisol은 관리에 주의가 필요한 종목에 속했다. 28종목에 대해 외부정도관리를 참여하는 전체 기관에 대한 변동계수 평균을 산출한 결과 상위 그룹에 속하는 종목(10.0% 이하)은 HGH, SCC-Ag이었으며, 하위 그룹(30.0% 이상)은 ATA, estradiol, TSI, thyroglobulin이었다. 6개 기관의 42종목에 대해 평가한 결과 변동계수가 3.7~12.2%로 하위 그룹과 상위 그룹이 3.3배의 차이를 보였다. 변동계수의 값이 높은 cortisol, ATA, AMA, renin, estradiol 검사들은 정밀도를 향상시키기 위한 개선 활동들이 지속적으로 이루어져야 할 것이다. 또한 HBs-Ab를 제외한 41종목에 대해 내부정도관리 및 외부정도관리, 기관 간 숙련도 참여기관의 전체 CV% 평균을 산출하여 비교한 결과 ATA, AMA, renin, estradiol 검사는 높은 허용범위 설정을 권장한다. 설정된 허용범위를 기준으로 체계적인 질 관리를 수행한다면 핵의학 검체검사 결과의 정확도 및 신뢰도를 향상시킬 수 있을 것으로 사료된다.

• 한국엔터테인먼트산업학회논문지
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• 제13권8호
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• pp.627-633
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• 2019

본 연구는 지역사회 노인을 대상으로 컴퓨터 기반 인지재활 프로그램 적용 시 백색소음이 기억력과 주의력에 미치는 영향을 알아보고자 하였다. 지역사회에 거주하는 70세 이상 노인 30명을 대상으로 연구를 진행하였다. 컴퓨터 기반 인지재활 프로그램은 COMCOG를 이용하여 총 6주간, 주 3회 30분의 프로그램으로 구성하였다. 기억력 및 주의력이 변화를 알아보기 위해 전산화 신경인지 기능 검사를 실시하였다. 기억력과 주의력은 실험군과 대조군 모두 실험 전에 비해 실험 후 향상되었음을 알 수 있었으며, 통계적으로 유의한 차이를 나타내었다(p<.05). 실험 후 집단 간 비교 검사 결과, 대조군과 실험군에 차이를 나타내었다. 기억력 검사에서는 역방향 시공간 폭 검사를 제외한 나머지 검사에서 통계적으로 유의한 차이를 나타내었으며(p<.05), 주의력 검사에서는 청각적 연속수행 및 시각적 연속수행 검사의 정반응 수에서 통계적으로 유의한 차이를 나타내었다(p<.05). 이상의 결과를 통해 컴퓨터 인지재활 프로그램이 노인의 기억력과 주의력 향상에 효과적이며, 백색소음 환경은 프로그램을 수행하는데 더욱 집중할 수 있도록 긍정적인 영향을 주는 것을 알 수 있었다.

• 한국멀티미디어학회논문지
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• 제25권1호
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• pp.124-134
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• 2022

Based on existing research, the psychological state of Chinese students has become a very significant issue that needs to be resolved. In addition to paying attention to the daily life and study of Chinese students, the psychological problems of Chinese students are also worthy of attention. At the same time, if the existing psychological problems are not resolved in time, serious consequences may result. Based on the ART(Attention Restoration Theory) theory, this article uses VR (Virtual Reality) content as a medium, uses 3D modeling software to build a healing scene that helps Chinese students improve their psychological and emotional state, and presents it in a VR device. To achieve the purpose of improving the psychological and emotional state of Chinese students. According to experimental tests, the VR recovery scene constructed by this method can help improve the psychological mood of Chinese international students who already have subliminal depression. The results of independent sample T-tests after data analysis experiments show that after the intervention of the experiment, the depression of the experimental group is significantly improved compared to the control group. It is proved that the method in this study is effective for the mentality and emotion of Chinese international students who have subliminal depression. There is a significant improvement effect.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• 제18권2호
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• pp.154-161
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• 2007

Objectives: The aim of the current study is to test for the association of DRD4 exon III VNTR polymorphism with attention-deficit hyperactivity disorder(ADHD) in Korean children population. Methods: 113 Korean children with ADHD, 102 parents, and 133 control subjects participated with the current study. The distribution of genotypes and alleles of DRD4 exon III VNTR in children with ADHD was compared with that in control subjects. In addition, 69 children with ADHD and their parents were analyzed using the transmission disequilibrium test(TDT). Results: We could not find any significant differences in the distribution of genotypes and alleles at DRD4 exon III VNTR polymorphism between children with ADHD and control subjects. In addition, there was no preferential transmission of long allele of DRD4 exon III VNTR polymorphism. Conclusion: These results suggest that DRD4 is not associated with ADHD in Korean children population.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• 제29권2호
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• pp.62-72
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• 2018

Objectives: The molecular mechanisms underlying attention-deficit hyperactivity disorder (ADHD) remain unclear. Therefore, this study aimed to identify the genetic susceptibility loci for ADHD in Korean children with ADHD. We performed a case-control and a family-based genome-wide association study (GWAS), as well as genome-wide quantitative trait locus (QTL) analyses, for two symptom traits. Methods: A total of 135 subjects (71 cases and 64 controls), for the case-control analysis, and 54 subjects (27 probands and 27 unaffected siblings), for the family-based analysis, were included. Results: The genome-wide QTL analysis identified four single nucleotide polymorphisms (SNPs) (rs7684645 near APELA, rs12538843 near YAE1D1 and POU6F2, rs11074258 near MCTP2, and rs34396552 near CIDEA) that were significantly associated with the number of inattention symptoms in ADHD. These SNPs showed possible association with ADHD in the family-based GWAS, and with hyperactivity-impulsivity in genome-wide QTL analyses. Moreover, association signals in the family-based QTL analysis for the number of inattention symptoms were clustered near genes IL10, IL19, SCL5A9, and SKINTL. Conclusion: We have identified four QTLs with genome-wide significance and several promising candidates that could potentially be associated with ADHD (CXCR4, UPF1, SETD5, NALCN-AS1, ERC1, SOX2-OT, FGFR2, ANO4, and TBL1XR1). Further replication studies with larger sample sizes are needed.