• Title/Summary/Keyword: artificial skin

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A Study on Transdermal Drug Delivery System with Microneedle System in the Field of Skin Care (마이크로니들을 이용한 경피약물전달의 피부 미용학적 접근)

  • Kim, Sung-Jun
    • KSBB Journal
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    • v.26 no.4
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    • pp.277-282
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    • 2011
  • The penetration of outside material into skin is not easy. It is since the skin, which is a very hard barrier, protects the body against outside chemical and physical stimulation. Microneedle system which can help improve drug penetration into skin is advancing variously in transdermal drug delivery system (TDDS) in the field of skin care. After inserting microneedle into skin by using electrical or artificial forces, it makes microhole and drug penetration easily and induces natural skin rejuvenation. Diffusion and penetration of drug by optical and electrical force of microneedle is better for fast and effective TDDS. This is more developed than the traditional method such as the manual stamp, roller, and meso gun. The drug absorbed into dermal layer by microneedle helps revive and repair damaged skin. In the future, utilization of microneedle for skin care will progress constantly because of its human-friendly biodegradable materials and the development of the no pain microneedle.

Frog-inspired programmable nano-architectures for skin patches and medical applications

  • Kim, Da Wan;Baik, Sang Yul;Kim, Jungwoo;Kim, Ji Won;Pang, Changhyun
    • Proceedings of the Korean Vacuum Society Conference
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    • 2016.02a
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    • pp.366-366
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    • 2016
  • Nanoscale observation of attachment systems of animals has revealed various exquisite multiscale architectures for essential functions such as gecko's locomotion, beetles' wing fixation, octopuses' sucking and crawling. In particular, the hierarchical 3-dimensional hexanonal nano-architectures in the tree frog's adhesion is known to have the capability of the enhancement of adhesion forces on the wet or rough surfaces due to the conformal contacts against rough surfaces and water-drainable micro channels. Here, we report that tree frog-inspired patches using unique artificial 3-dimensional hexagonal structures can be exploited to form reversibly enhanced adhesion against various highly curved and rough surfaces in dry and wet condition. To investigate the adhesion effect of micro-channels, we changed the arrangement of microstructure and spacing gaps between micro-channels. In addition, we introduced the 3-dimensional hexagonal hierarchical architectures to artificial patches to enhance to conformal contacts on the various rough surfaces such as skin and organs. Using the robust adhesion properties, we demonstrated the self-drainable and comfortable skin-attachable devices which can measure EKG (electrokardiogramme) for in-vitro diagnostics. As a result, bio-inspired programmable nano-architectures can be applied in versatile devices such as, medical patches, skin-attachable electronics etc., which would shed light on future smart, directional and reversible adhesion systems.

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Immediate Near-Total Scalp Reconstruction with Artificial Dermis on Exposed Calvarium

  • Park, Sooyeon;Han, Ki Taik;Kim, Min Cheol;Lim, Jin Soo
    • Archives of Craniofacial Surgery
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    • v.17 no.4
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    • pp.233-236
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    • 2016
  • Scalp defect management is complicated secondary to reduced laxity in the scalp and forehead area. For reconstruction of larger defects with exposed bone and loss of the periosteal layer, free flap reconstruction is one option for single-stage surgery, although the procedure is lengthy and includes the possibility of flap loss. We successfully performed a single-stage reconstruction of a large scalp defect using a combination of artificial dermis, split-thickness skin graft, and full-thickness skin graft following wide excision of a cutaneous angiosarcoma, and present our method as one option for the treatment of large oncologic surgical defects in patients who are poor candidates for free flap surgery.

Development and Performance Evaluation of Optimal Control logics for the Two-Position- and Variable-Heating Systems in Double Skin Facade Buildings (이중외피 건물 난방시스템의 발정제어 및 가변제어를 위한 최적로직의 개발 및 성능평가)

  • Baik, Yong Kyu;Moon, Jin Woo
    • KIEAE Journal
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    • v.14 no.3
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    • pp.71-77
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    • 2014
  • This study aimed at developing and evaluating performance of the two logics for respectively operating two-position- and variable-heating systems. Both logics control the heating system and openings of the double skin facade buildings in an integrated manner. Artificial neural network models were applied for the predictive and adaptive controls in order to optimally condition the indoor thermal environment. Numerical computer simulation methods using the MATLAB (Matrix Laboratory) and TRNSYS (Transient Systems Simulation) were employed for the performance tests of the logics in the test module. Analysis on the test results revealed that the variable control logic provided more comfortable and stable temperature conditions with the increased comfortable period and the decreased standard deviation from the center of the comfortable range. In addition, the amount of heat supply to the indoor space was significantly reduced by the variable control logic. Thus, it can be concluded that the optimal control method using the artificial neural network model can work more effectively when it is applied to the variable heating systems.

Recent Progress on Ionically Conductive Polymer Electrolyte for Electronic Skin Sensors

  • Kim, Jeong Hui;Jeong, Jung-Chae;Lee, Keun Hyung
    • Elastomers and Composites
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    • v.56 no.3
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    • pp.117-123
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    • 2021
  • Electronic skin (or E-skin) is an artificial smart skin composed of one or more than two sensors. E-skins detect external stimuli and convert them into electrical signals. Various types of E-skin sensors exist, including mechanical, physical, and chemical, depending on the detection signals involved. For wearable E-skins with superior sensitivity and reliability, developing conductors that possess both good elasticity and sensitivity is essential. Typical electrical conductors used in these sensors show very high sensitivity, but they have drawbacks such as non-linearity, irreversibility, and a narrow sensing range. To address these issues, stretchable and lightweight ionic conductors have been actively used in E-skin applications. This study summarizes the recent progress on various types of ionic conductors and ionic-conductor-based E-skin sensors.

A Biomimetic Artificial Neuron Matrix System Based on Carbon Nanotubes for Tactile Sensing of e-Skin (인공촉각과 피부를 위한 탄소나노튜브 기반 생체 모방형 신경 개발)

  • Kim, Jong-Min;Kim, Jin-Ho;Cha, Ju-Young;Kim, Sung-Yong;Kang, In-Pil
    • Journal of Institute of Control, Robotics and Systems
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    • v.18 no.3
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    • pp.188-192
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    • 2012
  • In this study, a carbon nanotube (CNT) flexible strain sensor was fabricated with CNT based epoxy and rubber composites for tactile sensing. The flexible strain sensor can be fabricated as a long fibrous sensor and it also may be able to measure large deformation and contact information on a structure. The long and flexible sensor can be considered to be a continuous sensor like a dendrite of a neuron in the human body and we named the sensor as a biomimetic artificial neuron. For the application of the neuron in biomimetic engineering, an ANMS (Artificial Neuron Matrix System) was developed by means of the array of the neurons with a signal processing system. Moreover, a strain positioning algorithm was also developed to find localized tactile information of the ANMS with Labview for the application of an artificial e-skin.

Melanoma Classification Using Log-Gabor Filter and Ensemble of Deep Convolution Neural Networks

  • Long, Hoang;Lee, Suk-Hwan;Kwon, Seong-Geun;Kwon, Ki-Ryong
    • Journal of Korea Multimedia Society
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    • v.25 no.8
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    • pp.1203-1211
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    • 2022
  • Melanoma is a skin cancer that starts in pigment-producing cells (melanocytes). The death rates of skin cancer like melanoma can be reduced by early detection and diagnosis of diseases. It is common for doctors to spend a lot of time trying to distinguish between skin lesions and healthy cells because of their striking similarities. The detection of melanoma lesions can be made easier for doctors with the help of an automated classification system that uses deep learning. This study presents a new approach for melanoma classification based on an ensemble of deep convolution neural networks and a Log-Gabor filter. First, we create the Log-Gabor representation of the original image. Then, we input the Log-Gabor representation into a new ensemble of deep convolution neural networks. We evaluated the proposed method on the melanoma dataset collected at Yonsei University and Dongsan Clinic. Based on our numerical results, the proposed framework achieves more accuracy than other approaches.

A Study on Expressed Characteristics to SKIN On the Contemporary Interior Design (현대실내공간에서 나타난 ′SKIN′ 표현특성에 관한 연구)

  • 이희정;이정욱
    • Proceedings of the Korean Institute of Interior Design Conference
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    • 2003.05a
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    • pp.135-138
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    • 2003
  • Skin, the complex membrane that holds the body together, also embraces the full spectrum of design today-from product to architecture, fashion, and media. Every object has a skin. thick or thin, smooth or rough, porous or impermeable, the skin is the line between a hidden interior and an exterior we experience. Skin: Surface, Substance and Design is a compendium of products, furniture, fashion, architecture and media that expand the limits of what we understand as surface. Reflecting the convergence of natural and artificial life, this provocative a thesis shows how enhanced and simulated skins appear everywhere in today's world.

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A Study on the Development of High-Intensity Focused Ultrasound Skin Treatment System Through Frequency Output Control Optimization (주파수 출력 제어 최적화를 통한 고강도 집속 초음파 피부치료 시스템 개발 연구)

  • Park, Jong-Cheol;Kim, Min-Sung
    • Journal of Korea Multimedia Society
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    • v.25 no.8
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    • pp.1022-1037
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    • 2022
  • It is important to develop a transducer that generates uniform output power through frequency control of the HIFU at 4 MHz frequency for the high intensity focused ultrasound (HIFU) skin diseases treatment. In this paper, a 4 MHz frequency band HIFU system for skin disease treatment was designed, manufactured and developed. In HIFU, even for the ultrasonic vibrator in the 4 MHz frequency band, the characteristics of the output power of the HIFU are different depending on the difference in the thickness of the PZT material. Through the development of a system amplifier, the sound output of the HIFU transducer was improved to more than 48 W and uniform output power control was possible. And, it is possible to control the output power even in a frequency band of 4.0 to 4.7 MHz, which is wider than 4.0 MHz, and shows the resonance frequency of the transducer. The maximum output power for each frequency was 49.969 W and the minimum value was 48.018 W. The maximum output power compared to the minimum output power is 49.969 W, which is uniform within 4.1%. It was confirmed that the output power of the HIFU through the amplifier can be uniformly controlled in the 4 MHz frequency band.