• Journal of Ginseng Research
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• v.18 no.2
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• pp.113-117
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• 1994

To assess a polential relationship of Korean ginseng to allergic reactions, the effect of Korean ginseng on the total IgE in serum as an allergologic parameter was investigated in humans. Serum total IgE levels were measured in 8 subjects who have been taking ginseng for more than 5 years, 4 subjects of weak constitution, 10 newly hired workers in the ginseng processing industry and 7 normal subjects unexposed to Korean ginseng as control group. Blood samples were taken before and after the exposure to Korean ginseng. Total IgE levels after the exposure to Korean ginseng were not significantly different from those before the exposure within each group. And also, the IgE levels of control subjects were not significantly different compared with those of other groups. These results suggest that the exposure to Korean ginseng dose not affect significantly the IgE immune response of the subjects.

• The Korea Journal of Herbology
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• v.27 no.2
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• pp.31-36
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• 2012

Objective : For the purpose of making use the wild edible plants of Ulleung island smoothly, this study was designed. Method : For the first time, I searched the wild edible plants of Ulleung island from various data. And I examined herbological books and research papers on the wild edible plants of Ulleung island. Result : The herbaceous plants in Ulleung island were 12 family and 22 species, Compositae and Liliaceae plants take the highest number of them. The woody plants in Ulleung island were 1 family(Araliaceae) and 2 species. The herbal medicines that originated from the wild edible greens of Ulleung island were 25 species. The herbal medicines that have the effects of clearing away heat(淸熱), eliminating toxin(解毒), subduing swelling(消腫) and promoting blood circulation to remove blood stasis(活血祛瘀) take the highest number of the effects of these herbal medicines. Conclusion : For the purpose of making use the wild edible plants of Ulleung island smoothly, we should recognize not only medical benefits but also matters that pay special attention.

• Natural Product Sciences
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• v.12 no.3
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• pp.119-121
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• 2006

Four 3,4-seco-lupane trierpenoids were isolated from the MeOH extract of the leaves of Acanthopanax divaricatus forma flavi-flos Yook by using various column chromatography. The chemical structures of isolates were identified as chiisanogenin, chiisanoside, isochiisanoside and 11-deoxyisochiisanoside on the basis of physico-chemical and spectroscopic date($^1H-NMR,\;^{13}C-NMR$M$, 2D-NMR and FAB-MS). These compounds were isolated for the first time from A. divaricatus forma flavi-flos.

• Korean Journal of Pharmacognosy
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• v.8 no.1
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• pp.31-34
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• 1977

The chemical constituents of root bark of Acanthopanax sessiliflorum Seemann(Araliaceae) which is distributed in southern region of Korea are studied. The five kinds of chemical constituents are isolated from MeOH extract of root bark by column fractionation and purified by recrystallization. Substance $I{\sim}III$ were identified as stigmasterol, ${\beta}-sitosterol$ and campesterol. Substance IV is suggested as a lignan substance based on chemical and spectral discussions. The molecular formula of substance $V\;show\;C_{20}H_{18}O_6$ and its melting point is $120.5{\sim}121.5^{\circ}$. Due to the spectral data, it is confirmed that substance V is a (+) sesamin of lignan.

• Korean Journal of Pharmacognosy
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• v.21 no.3
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• pp.235-238
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• 1990

Fatty acids, sterols and amino acids were confirmed from seeds of Acanthopanax senticosus for. inermis Harms. Fatty acids were isolated from petroleum ether extract and identified by gas liquid chromatography. Its composition was myristic acid, palmitic acid, stearic acid, oleic acid, linoleic acid, linolenic acid and behenic acid. The composition of sterols that isolated from n-hexane extract were determined by GC/MS. It was confirmed to be a mixture of ${\beta}-sitosterol$ and stigmasterol. And several kinds of amino acids-cysteic acid, threonine, serine, proline, glutamic acid, glycine, alanine, valine, isoleucine, leucine, histidine, lysine and arginine-were confirmed from water fraction.

• Korean Journal of Pharmacognosy
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• v.10 no.3
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• pp.103-107
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• 1979

Acanthopanax sessiliflorum of family of Araliaceae, Korean wild plant was first described by T. $N_{AKAI}$ in 1909. Although Acanthopanax has been formerly classified by 2 genera, 8 species, but it could be rearranged by 1 genus, 7 species. A. sessiliflorum among 7 species was distributed almost all over the country and A. senticosus was available mainly in the northern part and distribution of A. senticosus was coming down southward alongside Mt. Taibaik and Mt. Sobaik from North. A. chiisanense was mainly distributed over the southern part in the middle area, and the other 4 species were rarely distributed in limited places.

• Journal of Microbiology and Biotechnology
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• v.14 no.1
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• pp.202-204
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• 2004

Polysaccharides and saponins were isolated from the root of Panax ginseng C.A. Meyer (Family Araliaceae), treated at various temperatures, and their inhibitory effects on rotavirus were investigated. As the temperature of processing increased, the molecular weight of the polysaccharides decreased, but the yields of water extracted increased. These polysaccharides inhibited rotavirus infection in MA104 cells, but there were no significant differences in rotavirus infection-inhibitory potency. However, ginseng saponins did not exhibit rotavirus infection-inhibitory activity.

• Korean Journal of Pharmacognosy
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• v.37 no.1 s.144
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• pp.1-10
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• 2006

'O Ga Pi Ip' has been used in Korea to cure rheumatism, neuralgia, edema, dematopathy, and impotence. The botanical origin of the crude drug has not been confirmed pharmacognostically. To clarify the botanical origin of 'O Ga Pi Ip', the morphological and anatomical characteristics of the leaves of Acanthopanax species growing in Korea and Japan, A. chi-isanensis Nakai, A. Koreanum Nakai, A. rufinerve Nakai, A. senticosus (Rupr.et Maxim). Harms, A senticosus (Rupr.et Maxim.) for inermis Harms, A. seoulense Nakai, A sessiliflorus (Rupr. et Maxim.) Seem, A. divaricatus Seem, A. sieboldianum Makino were compared. As a result, it was determined that 'O Ga Pi Ip' was the leaf of A. sessiliflorus (Rupr. et Maxim.) Seem, A chiisanensis Nakai, and A. koreanum $Nakai_I$.

• Natural Product Sciences
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• v.9 no.3
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• pp.158-160
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• 2003

Polyacetylenes were isolated from Panax ginseng C.A. Meyer (Family Araliaceae), and their inhibitory effects on growth, infection and VacA vacuolation of Helicobacter pylori (HP) were investigated. Ginseng polyacetylenes did not inhibit the infection of HP into KATO cells. However, polyacetylenes inhibited HP growth and vacuolation of Hela by VacA toxin. Panaxytriol showed the most potent inhibition with $IC_{50}$ values of 0.05 and 0.046 mg/ml, respectively.

• Korean Journal of Pharmacognosy
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• v.25 no.1
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• pp.35-40
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• 1994

Aqueous extreact of fresh ginseng (AFG) was examined for the antigenicity in Hartley guinea pigs in comparision with ovalbumin (OVA). When guinea pigs were sensitized with AFG emulsified with complete Freund's adjuvant (CFA), these animals showed negative reactions in active systemic anaphylaxis (ASA), active cutaneous anaphylaxis (ACA) and passive cutaneous anaphylaxis (PCA) tests and passive hemagglutination (PHA) reaction. On the contrary, when guinea pigs were sensitized with OVA emulsified with CFA as positive controls, these animals disclosed positive reactions in ASA, ACA and PCA tests and PHA reaction. From these results, AFG was considered not to possess antigenic properties in guinea pigs. In addition, the dose levels of AFG empolyed in the present experiment were confirmed not to suppress immune reactions.