• 한국지하수토양환경학회지:지하수토양환경
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• 제25권2_spc호
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• pp.28-54
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• 2020

Even though a systematic sampling approach is very crucial in both the general and detailed investigation phases to produce the best conceptual site model for contaminated sites, the concept is not yet established in South Korea. The U.S. Environmental Protection Agency (EPA) issued the 'Strategic Sampling Approaches Technical guide' in 2018 to help environmental professionals choose which sampling approaches may be needed and most effective for given site conditions. The EPA guide broadly defines strategic sampling as the application of focused data collection across targeted areas of the conceptual site model (CSM) to provide the appropriate amount and type of information needed for decision-making. These strategic sampling approaches can prevent the essential data from missing, minimize the uncertainty of projects and secure the data which are necessary for the important site-decisions. Furthermore, these provide collaborative data sets through the life cycle phases of projects, which can generate more positive proofs on the site-decisions. The strategic sampling approaches can be divided by site conditions. This technical guide categorized it into eight conditions; High-resolution site characterization in unconsolidated environments, High-resolution site characterization in fractured sedimentary rock environments, Incremental sampling, Contaminant source definition, Passive groundwater sampling, Passive sampling for surface water and sediment, Groundwater to surface water interaction, and Vapor intrusion. This commentary paper introduces specific sampling methods based on site conditions when the strategic sampling approaches are applied.

• Journal of Ginseng Research
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• 제48권4호
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• pp.373-383
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• 2024

Background: Network pharmacology has emerged as a powerful tool to understand the therapeutic effects and mechanisms of natural products. However, there is a lack of comprehensive evaluations of network-based approaches for natural products on identifying therapeutic effects and key mechanisms. Purpose: We systematically explore the capabilities of network-based approaches on natural products, using Panax ginseng as a case study. P. ginseng is a widely used herb with a variety of therapeutic benefits, but its active ingredients and mechanisms of action on chronic diseases are not yet fully understood. Methods: Our study compiled and constructed a network focusing on P. ginseng by collecting and integrating data on ingredients, protein targets, and known indications. We then evaluated the performance of different network-based methods for summarizing known and unknown disease associations. The predicted results were validated in the hepatic stellate cell model. Results: We find that our multiscale interaction-based approach achieved an AUROC of 0.697 and an AUPR of 0.026, which outperforms other network-based approaches. As a case study, we further tested the ability of multiscale interactome-based approaches to identify active ingredients and their plausible mechanisms for breast cancer and liver cirrhosis. We also validated the beneficial effects of unreported and top-predicted ingredients, in cases of liver cirrhosis and gastrointestinal neoplasms. Conclusion: our study provides a promising framework to systematically explore the therapeutic effects and key mechanisms of natural products, and highlights the potential of network-based approaches in natural product research.

• Journal of Korean Neurosurgical Society
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• 제30권12호
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• pp.1361-1368
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• 2001

Objective : "Paraclinoid" aneurysms include those aneurysms arising from the internal carotid artery between the site of emergence of the carotid artery from the roof of the cavernous sinus and the origin of the posterior communicating artery. The authors reviewed and analysed the results of surgical approaches to paraclinoid aneurysms treated with transcranial surgery and endovascular surgery. Methods : Between January 1998 and May 1999, 14 patients were treated surgically through ipsilateral and contralateral pterional approaches, and anterior interhemispheric approach, and endovascular surgery for paraclinoid aneurysms. All transcranial approaches were performed by same surgeon. The medical records, neuroimaging studies and videotapes which had been recorded operations were reviewed retrospectively. Results : Twelve patients presented with subarachnoid hemorrhage and ICH. Nine of fourteen patients had multiple aneurysms. Thirteen cases were small and one was a large aneurysm. Six patients were treated through ipsilateral approaches, six contralateral pterional approaches, one anterior interhemispheric approach and one primarily by GDC embolization. All aneurysms treated through contralateral approaches were multiple aneurysms. Neck clipping was performed in 9(69.2%) of the thirteen aneurysms, wrapping in four cases, among them three cases were followed by GDC embolization. The surgical outcomes were : Glasgow Outcome Scale(GOS) I 71.4%, GOS II 21.4% and GOS V 7.1%. Conclusion : The surgical approaches to paraclinoid aneurysms should be chosen after careful anatomical evaluation of aneurysm and its neighboring structures. 3D-CT angiography and/or the raw data of MR angiography were useful. This study supports the usefulness of the contralateral approach to paraclinoid aneurysm associated with multiple aneurysms, unruptured and small aneurysms whose dome projecting medially, superiorly and dorsally. The determination of contralateral approach to small and medially projecting paraclinoid aneurysm may be stressful to operator, thus we believe anterior interhemispheric approach is better alternated. Also we recommend the endovascular surgery after reinforcement of aneurym neck and dome in the case with difficulty in clipping.

• 한국보육지원학회지
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• 제1권1호
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• pp.125-146
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• 2005

본 연구는 보육시설의 물리적인 환경 및 교사의 창의적인 역할수행과 유아창의성간의 관계에 대해 알아보고자 하였다. 연구의 목적을 달성하기 위해, 유아 182명을 대상으로 Torrance(1981)가 개발한 창의적 사고 검사인 TCAM(Thinking Creativity in Action and Movement)을 실시하여 창의성을 측정하였다. 또한 해당 어린이집 담임교사 28명을 대상으로 보육시설의 물리적 환경 및 교사의 창의적 역할수행에 관한 질문지 조사를 실시하였다. 그에 따른 연구의 결과는 다음과 같다. 첫째, 유아의 성별에 따른 유아의 창의성은 유의미한 차이가 없었으나, 유아의 연령에 따른 유아의 창의성은 창의성의 하위영역인 상상력에서 연령이 증가함에 따라 상상력이 유의미하게 높아지는 것으로 나타났다. 둘째, 물리적 환경의 질적 수준이 높을수록 유아의 창의성이 유의미하게 높아지는 것으로 나타났다. 셋째, 교사가 창의적인 역할을 유아에게 적극적으로 수행할수록 유아의 창의성은 유의미하게 높아지는 것으로 나타났다. 넷째, 보육시설의 물리적 환경 및 교사의 창의적 역할수행은 유아의 창의성과 유의미한 정적 상관이 있는 것으로 나타났다. 다섯째, 보육시설의 물리적 환경 및 교사의 창의적 역할수행은 유아의 창의성에 유의미한 영향을 미치는 것으로 나타났다. 따라서 보육시설의 물리적 환경의 질적 수준이 높고, 교사가 유아에게 창의적인 역할을 수행하기 위해 노력할수록 유아의 창의성이 더욱 성장하고 발달할 수 있음을 알 수 있다.

• 한국정보디스플레이학회:학술대회논문집
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• 한국정보디스플레이학회 2004년도 Asia Display / IMID 04
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• pp.436-439
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• 2004

Most of past image processing systems have been designed independent of image contents. Now, evolving computation power is making the "image-dependent" elegant algorithms possible to get the better image renditions on display. This paper introduces our recent approaches to quality and pleasant imaging based on image-dependent. Three typical approaches to comfortable "Sharpness", "Lightness", and "Color" renditions on display image arc presented.

• 대한핵의학회:학술대회논문집
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• 대한핵의학회 2001년도 제40차 춘계학술대회 및 연수교육
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• pp.51-55
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• 2001

Regional MBF and MRGlc can be accurately estimated with N-13 ammonia and FDG PET using tracer kinetic methods including compartmental and non-compartmental approaches. Compartment modeling approaches are physiologically well characterized, but are methodologically more complicated. Noncompartmental analysis are easier to implement while the limitations and assumptions of the methods should be understood prior to the application of the method.

• 한국철도학회:학술대회논문집
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• 한국철도학회 2003년도 추계학술대회 논문집(II)
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• pp.334-339
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• 2003

The Aim of this paper is to indicate strategic approaches for china railway operation. For this purpose, the paper discusses logistic policies and networks of China, conditions and problems in Chinese railway

• 한국전산유체공학회:학술대회논문집
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• 한국전산유체공학회 2006년도 추계 학술대회논문집
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• pp.28-29
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• 2006

Computational approaches for the aerodynamic design and optimization are introduced. In this paper the aerodynamic design methods and applications, which have been applied to various aerospace vehicles at Konkuk University, are introduced. It is shown that system approximation technique reduces computational cost for CFD analysis and improves efficiency for the design optimization process.

• 대한안전경영과학회:학술대회논문집
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• 대한안전경영과학회 2003년도 추계학술대회
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• pp.329-333
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• 2003

This paper reviews differences between the traditional investment evaluation methods and real option approaches. This study considers management flexibility, contingency and volatility from a strategic management perspective. The roles of various real option approaches are discussed.

• 대한전기학회:학술대회논문집
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• 대한전기학회 1993년도 하계학술대회 논문집 A
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• pp.299-302
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• 1993

Some well known order reduction methods are briefly described and a nev order reduction technique is introduced. A comparison of the various classes of order reduction approaches are indicated. Furthermore, the question is raised how order reduction should be executed with respect to controller design. Finally, by means of an example, results of the discussed approaches are compared.