• Anxiety and mood
• /
• v.15 no.2
• /
• pp.122-126
• /
• 2019

Objective : Dynamic proteolysis, through the ubiquitin-proteasome system, is an important molecular mechanism for the constant regulation of synaptic plasticity and stress responses in humans. In this study, we examined whether genetic variants in the ubiquitin-specific peptidase (USP) genes were associated with psychological traits of resilience and susceptibility to neuropsychiatric disorders for each gender. Methods : A total of 344 Korean healthy youths (190 males, 154 females) were included in the study. A genotyping of rs2241646 of USP2 and rs346006 of USP46 was performed. The Connor-Davidson Resilience Scale and Brief Fear of Negative Evaluation Scale were administered for measuring trait resilience and social anxiety, respectively. The genetic associations of the USP variants were tested using multiple analyses of covariance with psychological traits as dependent variables after controlling for age in each gender. Results : For USP2 rs2241646, women with the TT genotype showed significantly higher resilience and lower social anxiety, as compared to those carrying the C allele. There were no associations between USP46 rs346005 and the psychological traits in both genders. Conclusions : The present study showed a possible genetic association between the USP2 rs2241646 and stress resilience and trait anxiety in women. The findings suggest that ubiquitin-proteasome system may be related to the resilience and susceptibility to stress-related neuropsychiatric disorders such as anxiety disorders, possibly through the regulation of dynamic proteolysis responses to stress.

• Journal of Korean Biological Nursing Science
• /
• v.24 no.4
• /
• pp.227-234
• /
• 2022

Purpose: Smoking is a way of coping with anxiety and stress. This study aimed to identify the effects of forest-thermal combined therapy on anxiety and depression in smokers who desire to quit smoking. Methods: Thirty participants were included in the study, 15 in the experimental group and 15 in the control group. Those in the experimental group participated in a three-day forest-thermal combined therapy program. The program includes forest walks, meditation and thermal therapy in the charcoal kiln. Results: Before and after the program, physiological indicators such as cortisol, heart rate variability, and serotonin anxiety level using the state-trait anxiety inventory (STAI), and stress level using the psychosocial well-being index (PWI) were measured in both groups. The differences in STAI (p=.012) and PWI (p=.006) scores between the experimental and control groups were statistically significant. However, cortisol, heart rate variability, and serotonin were not significantly different between the two groups after the program. Conclusion: These results show that forest-thermal combination therapy effectively reduces anxiety and stress in smokers. It suggests that forest-thermal therapy can potentially increase smoking cessation rates.

• Journal of the Korean Home Economics Association
• /
• v.48 no.9
• /
• pp.103-111
• /
• 2010

The purpose of this study was to investigate the effects of perceived parental acceptance on social anxiety and depressive symptoms in children. Seven hundred and thirty eight 5th and 6th graders completed questionnaires. Regression analyses indicated that low levels of paternal acceptance was associated with higher social anxiety and depressive symptoms. Gender was a moderator of the effects of maternal acceptance on social anxiety and depressive symptoms. With high levels of maternal acceptance, girls were significantly less likely to report social anxiety and depressive symptoms, compared to boys. These results highlight the important role of parental acceptance in manifestations of social anxiety and depressive symptoms and clarify the relation of maternal acceptance to social anxiety and depressive symptoms as a function of gender.

• Journal of Korean Academy of Nursing
• /
• v.40 no.5
• /
• pp.650-661
• /
• 2010

Purpose: Work-related anxiety and depression are frequent work-related mental health problems. In this study the relationship between workplace violence and work-related anxiety and/or depression among Korean employees was evaluated. Methods: Data were obtained from the Korean Working Condition Survey of 2006. Participants were 9,094 Korean workers aged 15-64 yr. Multiple logistic regression using SAS version 9.1 was used. Results: The incidence of work-related anxiety, work-related depression and workplace violence were 4.5%, 3.5%, and 1.8% respectively. When personal and occupational risk factors were adjusted, workplace violence was significantly associated with work-related anxiety and depression (OR for anxiety: 4.07, CI: 2.62-6.34; OR for depression: 4.60, CI: 2.92-7.25). Work-related anxiety was significantly related to type of employment, working period at present workplace, work time, shift work, job demand, and social support from superiors. Factors influencing work-related depression were gender, education, alcohol consumption, company size, type of employment, working period at present workplace, work time, shift work, and job demand. Conclusion: To promote psychological health in workers there is a need to develop work-related anxiety and depression prevention programs and to decrease in workplace violence. In developing these programs, consideration should be given to personal factors, working conditions, and psychosocial working environments.

• Journal of Korean Medical Science
• /
• v.33 no.45
• /
• pp.284.1-284.12
• /
• 2018

Background: Posttraumatic stress symptoms (PTSS) in patients with psychological trauma lead to poor health-related quality of life. Understanding of the relationships among PTSS, anxiety, depression, and illness intrusiveness will guide the development of efficient approaches to enhance subjective well-being in patients with psychological trauma. This study investigated whether anxiety and depression mediate the relationship between PTSS and illness intrusiveness in the hope of providing more comprehensive and effective trauma treatment. Methods: Psychiatric outpatients who visited the trauma clinic of a university hospital (n = 260) participated in this study. Assessments were conducted for PTSS, anxiety, depression, and illness intrusiveness. Structural equation modeling and path analysis were performed to analyze the mediating effects of anxiety and depression on the relationship between PTSS and illness intrusiveness. Results: PTSS had both direct and indirect exacerbating effects on illness intrusiveness. Anxiety exhibited the largest direct exacerbating effect on illness intrusiveness. The indirect effects of PTSS on illness intrusiveness through anxiety alone and through a depression-to-anxiety pathway were significant, but the indirect effect through depression alone was not. Conclusion: The findings demonstrate that anxiety, both independently and as part of an interrelated pathway with depression, partially mediates the relationship between PTSS and illness intrusiveness. Appropriate interventions and a comprehensive approach to alleviate anxiety and depression could mitigate the negative effects of PTSS on illness intrusiveness in patients with psychological trauma.

• Child Health Nursing Research
• /
• v.10 no.2
• /
• pp.188-195
• /
• 2004

Purpose: This study was to identify and to search the related disposition of the pattern of anxiety and coping in mothers of children with nephrotic syndrome through the use of Q-methodology. Method: 34 Q-samples were finally selected in the concept of anxiety and coping. A P-sample of 35 was selected the mothers of children with nephortic syndrome. The result of the Q-sorting was coded and analyzed using QUANL PC program. Result: There were 3 types of special opinion. The first type is called ' Pursuit of hope type.' Members of this type were cope with the anxiety by spiritual behavior like a pray, positive thinking. The second type is called 'Worry about reality type.' Members of this type were to be filled with apprehension like an indigestion, insomnia. The third type is called ' Solving problem type.' Members of this type were cope with the humanity effort by conversation. Conclusion: The mothers of children with nephrotic syndrome were used various coping patterns to cope with the anxiety conditions that their child were result from admission to hospital and treatment of the disease. Therefore, nursing assessment and nursing intervention skills have to develop in consideration of the subjectivity of coping about anxiety in each individual.

• Korean Journal of Adult Nursing
• /
• v.25 no.1
• /
• pp.95-104
• /
• 2013

Purpose: The purpose of this study was to investigate the level of resilience, family support, anxiety and depression in patients with hematologic malignancy, and to determine modifiable psychosocial factors that affect their resilience. Methods: Data were collected from 104 patients undergoing curative therapy at 'S' hospital in Seoul. The data were collected from April to May, 2012. The questionnaires included Korean Version of Connor-Davidson Resilience Scale, Family Support Scale and Hospital Anxiety-Depression Scale. The data were analyzed using descriptive statistics, t-test, ANOVA, Pearson correlation and stepwise multiple regression. Results: Resilience had statistically significant correlation with family support (r=.43, p<.001), anxiety (r=-.49, p<.001) and depression (r=-.52, p<.001). Factors influencing resilience were depression, family support, anxiety and time since diagnosis with R-sq. value of 36%. Conclusion: The results of the study show that family support, anxiety and depression have important influences on resilience of patients with hematologic malignancy. Thus, family support needs to be reinforced when developing and implementing nursing intervention, and nurses need to intervene to reduce anxiety and depression of patients with hematologic malignancy.

• Journal of Korean Academy of Nursing
• /
• v.28 no.3
• /
• pp.616-624
• /
• 1998

The purpose of this study was to contribute to maternal nursing in early postpartum stage and to neonatal nursing. Data were collected through self-report questionnaires which were constructed to include parental role stress scale, state-trait anxiety scale, and perception of the newborn scale. The subjects consisted of 100 mothers in the early postpartum stage at three hospitals in the Kyoung-In area, from November 8 to December 26, 1997. The data were analyzed by an SPSS program. The results are as follows ; 1. The mean of parental role stress of mothers in the early postpartum stage was 10.70$\pm$2.63. The means of state anxiety and trait anxiety of mothers were 36.29$\pm$8.45 and 38.53$\pm$8.36. The mean of perception of the newborn was 2.65$\pm$5.05, and 59% of mothers rated their newborn as better than the average newborn. 2. The level of parental role stress correlated to the level of state anxiety and trait anxiety. The level of state anxiety and trait anxiety were also related. The level of perception of the newborn was related to the level of state anxiety and trait anxiety. 3. Mothers who did not want the pregnancy, whose newborns were girls, and who already had one child had higher state anxiety than those who did not. Mothers who already had one child, and whose newborn had no specific signs had higher trait anxiety than those who did not. Mothers who professed a religions had a higher perception of the newborn than those who did not. The above findings indicate that the levels of parental role stress, state anxiety, trait anxiety and perception of the newborn of mothers in early postpartum stage were correlated. Therefore nursing intervention for reducing stress and anxiety, and improving perception of the newborn should be provided for mothers in early postpartum stage.

• Korean Journal of Childcare and Education
• /
• v.10 no.3
• /
• pp.69-84
• /
• 2014

The purpose of this study was to examine the influence of educare teachers' science education knowledge and attitudes towards science on science teaching anxiety. 259 teachers of young children were recruited from 19 daycare centers and the data were analyzed through frequency, percentage, Pearson's correlations using PASW 18.0 and structure equation modeling using AMOS 7.0. The findings are as follows. First, educare teachers showed more than median scores in all science education knowledge, attitude towards science and science teaching anxiety. Second, in total 57% of the variance in teachers' science teaching anxiety was accounted for by teachers' science education knowledge and attitude towards science. This result implied that teachers' science education knowledge and attitude towards science should be improved in order to reduce teachers' science teaching anxiety.

• Journal of Korean Biological Nursing Science
• /
• v.19 no.3
• /
• pp.206-213
• /
• 2017

Purpose: The purpose of the study was to compare salivary cortisol levels, self-reported occupational stress, and anxiety before duty to those after duty in the shift and regular work nurses, and the relationships among them. Methods: Thirty nurses working in a tertiary hospital participated in the study. Salivary specimens were collected before and after daytime duty for 2 days. The occupational stress and state anxiety were also evaluated using self-report questionnaires. Results: The average level of salivary cortisol was $0.40{\mu}g/dL$ before duty and $0.20{\mu}g/dL$ after duty in Korean nurses. Overall levels of salivary cortisol, self-reported occupational stress, and anxiety were higher in shift working nurses than regular working nurses. In shift working nurses, the salivary cortisol gap between before and after duty was attenuated on the first day of daytime duty. Significant positive correlation was found between the level of cortisol before duty and anxiety after duty. Conclusion: Strategies to alleviate occupational stress and anxiety are needed for shift working nurses, especially for those with elevated levels of cortisol. It seems to require 3days to recover from attenuated cortisol rhythm during nighttime duty in shift working nurses.