• Title/Summary/Keyword: antibacterial agent

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Comparison of Antibacterial Ability of Air Filter Media Treated with a Natural Antibacterial Agent by Three Treatment Methods (항균성 천연물질의 도포방법에 따른 에어필터 여재의 항균 특성 비교)

  • Park, Sun Young;Jung, Jae Hee;Hwang, Gi Byung;Bae, Gwi-Nam;Kim, Yong Pyo;Nho, Chu Won
    • Journal of Korean Society for Atmospheric Environment
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    • v.29 no.2
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    • pp.125-134
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    • 2013
  • Various antimicrobial technologies have been developed to inactivate bioaerosols in indoor environments. In this study, air filter media were treated with a natural antibacterial agent of Sophora flavescens in order to inactivate the bacteria collected on the air filter. Three treatment methods were applied to manufacture the test antibacterial air filter media: electrospray, nebulization and dip-coating methods. In case of electrospray and nebulization processes, the size distribution of aerosolized natural antibacterial agent was measured using a scanning mobility particle sizer. Staphylococcus epidermidis bacteria were aerosolized to test inactivation of the filter media treated with a natural antibacterial agent. The pressure drop and the antibacterial efficiency of the filter media increased with increasing the mass loading of natural antibacterial agent in each treatment method. The antibacterial efficiency per loaded antibacterial agent mass by the electrospray method was the highest and the filter treated by the dip-coating method was the lowest among three treatment methods.

Antibacterial Activity of Caryophylli Flos on the Growth of Dental Caries Bacteria, Streptococcus mutans KDJ-50 (구강균 Streptococcus mutans KDJ-50에 대한 정향의 향균효과)

  • Kwak, Dong-Ju;Nam, Sang-Yong;Chung, Suk-Min
    • Journal of Technologic Dentistry
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    • v.23 no.1
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    • pp.75-83
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    • 2001
  • This study was conducted to find antibacterial agent against growth of dental caries bacteria. St. mutans KDJ-50 from various medicinal plants of which safety was indetified. Medicinal plants used in this study was dried and grinded after purchased at Daegu yakryung sijang and Kyungsan jungang sijang. Medicinal plants extracted with 80% ethanol at boiling point for 3 hrs was used as antibacterial agent after freeze dried. This study was conducted to find antibacterial agent against growth of dental caries bacteria. St. mutans KDJ-50 from 32 medicinal plants of which safety was indetified. The result of using paper disc method. Caryophylli Flos. Coptidis Rhizoma. Phellodendri Cortex. Schizamdrae Fructs. Myristicae Semen, Crataegi Fructus and Acori Graminei Rhizoma was selected as antibacterial agent. The result of viable cell counting method. the antibacterial activity of Caryophylli Flos was highest among tested 7 medicinal plants followed by Phellodendri Cortex and Coptidis Rhizoma. The extinction effect of the St. mutans by Caryophylli Flos was shown with the addition of 0.5 (w/v) in the medium. The high antibacterial activity was acquired at high extraction temperature and long extraction temperature. The antibacterial activity of Caryophylli Flos was not effected by the concentration of ethanol.

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Antibacterial Activity of Topical Agent Extracted from Phellodendri cortex, Forsythia fructus and Glycyrrhizae radix Against Staphylococcus intermedius in Dogs (황백, 연교 및 감초 추출물을 이용한 국소제제의 Staphylococcus intermedius에 대한 항균효과)

  • Jeong Hyo-Hoon;Oh Tae-Ho
    • Journal of Veterinary Clinics
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    • v.22 no.4
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    • pp.353-356
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    • 2005
  • This study was performed to examine the antibacterial efecacy of topical agent extracted from Phellodendri cortex, Forsythia fructus and Glycyrrhizae radix as an alternative dermatological agent. Also, the most efficacious concentration of this agent and the skin-contact time inhibiting the vegetation of bacterial cells in various dilutions were determined. Five strains of Staphylococcus intermedius were exposed to various dilutions of this agent. The efficacy was assessed after exposure for time periods varying between 0 and 30 min. The antibacterial efficacy was shown to be the strongest at dilution of 1: 2. The number of viable organisms decreased significantly after 8 minutes of exposure time and was the smallest after 30 minutes of exposure time. This alternative dermatological agent is considered to be effective against Staphylococcus intermedius and has a potential to be a new topical agents far the treatment of pyoderma in dogs.

Antibacterial Finishing of Footwear Nylon 66 Fabric with Sericite and Medilite (견운모와 맥반석을 이용한 신발용 나일론 66직물의 항균가공)

  • Lee, Eon-Pil;Lee, Jae-Ho
    • Fashion & Textile Research Journal
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    • v.9 no.1
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    • pp.96-102
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    • 2007
  • Antibacterial finishing of nylon 66 fabrics was carried out with sericite and medilite which are a cheap price antibacterial agents and had excellent antibacterial effects. The particle size of sericite and medilite was 15 ${\mu}m$ and 30 ${\mu}m$. The antibacterial and deodorant ratio, tensile and tear strength, peel strength were examined to investigate the change of physical properties and antibacterial effect. The results are as follows. 1. Peel strength is increased with increasing adhesive content, and satisfied standard value of peel strength when adhesive content is 20 $g/m^2$. Also peel strength was decreased with increasing antibacterial agent content and particle size in the adhesives. 2. Tensile and tear strength were not related with antibacterial agent content in the adhesives. 3. Laundering nylon 66 fabric treated with antibacterial agent, the optimum content satisfying Korean Standard(KS) is 8%. The antibacterial and deodorant ratio were not affected by several types of adhesives.

Characterization of Antibacterial activity and Synthesis of Sulfanilamide Polymer using Crosslinking Agent (가교제를 이용한 Sulfanilamide 중합체의 합성과 항균특성)

  • Kim, Jong-Woan;Yoon, Chul-Hun;Hwang, Sung-Kwy;Kong, Seung-Dae;Lee, Han-Seab
    • Journal of the Korean Applied Science and Technology
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    • v.17 no.1
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    • pp.37-42
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    • 2000
  • Drug delivery system(DDS) have been actively studied for the past twenty years. Dual action agents are unique chemical entities comprised of two different types of antibacterial compounds covalently linked together in a single molecule in such a way that both components are able to exert their bactericidal properties. In spite of the advent of the antibacterial agent the sulfa agents are the most widely used antibacterial agent today. In this study, new antibacterials derivative was synthesized using glutaraldehyde such as crosslinking agent for the purpose of dual-action as DDS study. Antibacterial activity of these new synthetic derivative between their structures and activities were examined by disc diffusion method. As a result, new synthetic derivative exhibited the broad antibacterial activities against Gram(+) and Gram(-) bacilli. Especially, the antibacterial effect of new synthetic derivative against Gram negative(Esherichia. coli) was much stronger than that against Gram positive.

Modified membrane with antibacterial properties

  • Aryanti, P.T.P.;Sianipar, M.;Zunita, M.;Wenten, I.G.
    • Membrane and Water Treatment
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    • v.8 no.5
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    • pp.463-481
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    • 2017
  • Bacteria have been considered as a major foulant that initiates the formation of biofilm on the polymeric membrane surface. Some polymeric membranes are naturally antibacterial and have low fouling properties, however, numerous efforts have been devoted to improve their antibacterial performance. These modifications are mostly carried out through blending the membrane with an antibacterial agent or introducing the antibacterial agent on the membrane surface by chemical grafting. Currently, a significant number of researches have reported nanocomposite membrane as a new approach to fabricate an excellent antibacterial membrane. The antibacterial nanoparticles are dispersed homogenously in membrane structure by blending method or coating onto the membrane surface. Aim of the modifications is to prevent the initial attachment of bacteria to membrane surface and kill bacteria when attached on the membrane surface. In this paper, several studies on antibacterial modified membranes, particularly for water treatment, will be reviewed comprehensively. Special attention will be given on polymeric membrane modifications by introducing antibacterial agents through different methods, such as blending, grafting, and coating.

Natural Antibiotic Activity of Lactobacillus helveticus (Lactobacillus helveticus의 자연항생작용에 관한 연구)

  • Choi, Sang-Hun;Kim, Dong-Sin
    • Journal of Dairy Science and Biotechnology
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    • v.17 no.1
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    • pp.11-15
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    • 1999
  • The objective of this study was to extract and purity the antibacterial agent from the fermented milk with Lactobacillus helveticus CH-1. The extraction and purification of antibacterial agent from the Lb. helveticus fermented milk were carried out by methanol extraction, acetone extraction, Sephadex G-200 gel filteration and thin layer chromatography and the results were as followings. The antibacterial activity of methanol-acetone extraction showed antibacterial activity against test organisms, B. subtilis, E. coli, Pseu. fluorescens, Sal. typhimurium, Shi. flexneri, and Sta. aureus. Sephadex G-200 gel chromatography showed only antibacterial activity from 33 to 37th fractions of 60 fractions. The agent purified from TLC plate confirmed the antibacterial activity by the means of bioautography.

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Skin Patch Test and Antibacterial Properties of the Anti-microbial Agent and Melamine Resin Blend Treated Fabric (멜라민 수지와 항균제 혼합 수지 가공 직물의 항균성과 피부 적합성)

  • Chun, Tae-Ill;Park, Jung-Whan
    • Fashion & Textile Research Journal
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    • v.7 no.1
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    • pp.81-84
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    • 2005
  • Skin patch test and antibacterial properties of the reaction products between poly(hexamethyl biguanide) hydrochloride and trimethylol melamine on textile fabrics were examined. Antibacterial activities of anti-microbial agent treated samples are very good. The reduction ratios against four kinds of colonies are 99.9 % after repeated laundering ten times. Skin patch test results for anti-microbial agent treated samples are almost-negative by Hi-scope judgement and macroscopical judgement.

Evaluation of the physical properties and antibacterial effects on Candida albicans of denture base resin containing silver sulfadiazine (실버 설파다이아진이 첨가된 의치상용 레진의 Candida albicans에 대한 항균평가 및 물성 평가)

  • Yu-Ri Choi;Min-Kyung Kang
    • Journal of Korean society of Dental Hygiene
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    • v.23 no.6
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    • pp.459-466
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    • 2023
  • Objectives: The purpose of this study was to evaluate the physical properties and antibacterial activity of denture base resin with added silver sulfadiazine. Methods: Specimens were made from self-curing denture base resin and silver sulfadiazine as an inorganic antibacterial agent. For physical evaluation of the specimens, surface roughness, surface hardness, and contact angle were measured. Bacterial growth was assessed by optical densityat 600 nm (OD600) and colony forming units (CFU) measurements to confirm antibacterial activity. Results: There was no significant difference in surface roughness, surface hardness, and contact angle in the experimental group containing silver sulfadiazine compared to the control group. In contrast, the experimental group showed a significant decrease in antibacterial activity compared to the control group in terms of OD value. Analysis of CFU confirmed a significant decrease in colonies in the experimental group compared to the control group. Conclusions: Denture base resin containing silver sulfadiazine, an inorganic antibacterial agent, exhibited enhanced antibacterial activity without physical changes. In conclusion, the use of denture base resin containing inorganic antibacterial agents may be expected in the future.

Antibacterial Activity of Triterpenoids from Clerodendron trichotomum

  • Choi, Ji Won;Cho, Eun Ju;Lee, Dong Gu;Choi, Kyung;Ku, Jajung;Park, Kwang-Woo;Lee, Sanghyun
    • Journal of Applied Biological Chemistry
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    • v.55 no.3
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    • pp.169-172
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    • 2012
  • The aim of this research was to investigate the antibacterial activity of Clerodendron trichotomum. Antibacterial activities of the n-hexane, methylene chloride (MC), ethyl acetate, and n-butanol fractions from C. trichotomum were tested against Staphylococcus aureus, Escherichia coli, and Helicobacter pylori. The n-hexane and MC fractions showed antibacterial activity against H. pylori at a concentration of 1.7 mg/mL and showed inhibition zones of 10 and 11 mm in disc assay, respectively. Further testing of 22-dehydroclerosterol and ${\beta}$-amyrin (each 3.4 mg/mL) from the MC fraction of C. trichotomum revealed moderate antibacterial effects against E. coli, S. aureus, and H. pylori. In particular, ${\beta}$-amyrin showed clear zones of 12 and 13 mm against E. coli and H. pylori, respectively, suggesting its potential as an antibacterial agent. The active compounds from C. trichotomum might provide a promising therapeutic agent against infections by E. coli, S. aureus, and H. pylori.