Browse > Article

Antibacterial Activity of Topical Agent Extracted from Phellodendri cortex, Forsythia fructus and Glycyrrhizae radix Against Staphylococcus intermedius in Dogs  

Jeong Hyo-Hoon (College of Veterinary Medicine, Kyungpook National University)
Oh Tae-Ho (College of Veterinary Medicine, Kyungpook National University)
Publication Information
Journal of Veterinary Clinics / v.22, no.4, 2005 , pp. 353-356 More about this Journal
Abstract
This study was performed to examine the antibacterial efecacy of topical agent extracted from Phellodendri cortex, Forsythia fructus and Glycyrrhizae radix as an alternative dermatological agent. Also, the most efficacious concentration of this agent and the skin-contact time inhibiting the vegetation of bacterial cells in various dilutions were determined. Five strains of Staphylococcus intermedius were exposed to various dilutions of this agent. The efficacy was assessed after exposure for time periods varying between 0 and 30 min. The antibacterial efficacy was shown to be the strongest at dilution of 1: 2. The number of viable organisms decreased significantly after 8 minutes of exposure time and was the smallest after 30 minutes of exposure time. This alternative dermatological agent is considered to be effective against Staphylococcus intermedius and has a potential to be a new topical agents far the treatment of pyoderma in dogs.
Keywords
Staphylococcus inteymedius; Phellodendri cortex; Forsythia fructus; Glycyrrhizae radix; antibacterial efficacy; dog;
Citations & Related Records
연도 인용수 순위
  • Reference
1 Berkelman RL, Holland BW, Anderson RL. Increased bactericidal activity of dilute preparations of povidone-iodine solutions. J Clin Microbiol 1982; 15: 635-639
2 Kwochka KW. Recurrent pyoderma. In: Current Veterinary Dermatology. St. Louis: Mosby-year Book. 1993: 3-21
3 Nagle TM, Torres SM, Horne KL, Grover R, Stevens MT. A randomized, double-blind, placebo-controlled trial to investigate the efficacy and safety of a Chinese herbal product (P07P) for the treatment of canine atopic dermatitis. Vet Dermatol 2002; 12: 265-274   DOI   ScienceOn
4 Scott DW, Miller WH, Griffin CE. Dermatologic therapy. In: Muller & Kirk's Small Animal Dermatology, 6th ed. Philadelphia: WB Saunders. 2001: 207-273
5 Tanaka Y, Kikuzaki H, Fukuda H, Nakatani N. Antibacterial compounds of licorice against upper airway respiratory tract pathogens. J Nutr Sci Vitaminol 2001; 47: 270-273   DOI   ScienceOn
6 Kitagawa S, Nishibe S, Baba H. Studies on the Chinese crude drug 'Forsythia fructus' . Yakugaku Zasshi 1987; 107: 274-278
7 Guaguere E. Topical treatment of canine and feline pyoderma. Vet Dermato 1996; 7: 145-151   DOI   ScienceOn
8 Lozier SM. Topical wound therapy. In: Surgical Complications and Wound Healing in the Small Animal Practice. Philadelphia: WB Saunders. 1993: 63-88
9 Cuellar MJ, Giner RM, Recio MC, Manez S, Rios JS. Topical anti-inflammatory activity of some Asian medicinal plants used in dermatological disorders. Fitoterapia 2001; 72: 221-229   DOI   ScienceOn
10 DeBoer JD. Strategies for management of recurrent pyoderma in dogs. Vet Clin North Am Small Anim Pract 1990; 20: 1509-1525
11 Scott DW, Miller WH, Griffin CE. Bacterial skin diseases. In: Muller & Kirk's Small Animal Dermatology, 6th ed. Philadelphia: WB Saunders. 2001: 274-335
12 Nakamoto K, Sadamori S, Hamada T. Effects of crude drugs and berberine hydrochloride on the activities of fungi. J Prosthetic Dent 1990; 64: 691-694   DOI   ScienceOn
13 Higaki S, Nakamura M, Morohashi M. Activity of eleven kampo formulations and eight kampo crude drugs against Propionibacterium acnes isolated from acne patients: retrospective evaluation in 1990 and 1995. J Dermatol 1996; 23: 871-875
14 Higaki S, Hasegawa Y, Morohashi M. The correlation of kampo formulations and their ingredients on anti-bacterial activities against propionibacterium acnes. J Dermatol 1995; 22: 4-9
15 Lemarie RJ, Hosgood G. Antiseptics and disinfectants in small animal practice. Compend Contin Educ Pract Vet 1995; 17: 1339-1351
16 Hill PB, Moriello KA. Canine pyoderma. J Am Vet Med Assoc 1994; 204: 334-340
17 Fukai T, Marumo A, Kaitou K, Kanda T, Terada S, Nomura T. Anti-Helicobacter pylori flavonoids from licorice extract. Life Sciences 2002; 71: 1449-1463   DOI   ScienceOn
18 Tsukiyama RI, Katsura H, Tokuriki N, Kobayashi M. Antibacterial activity of licochalcone A against spore-forming bacteria. Antimicrob Agents Chemother 2002; 46: 1226-1230   DOI   ScienceOn
19 Koch HJ, Vercelli A. Shampoos and others topical therapies. In: Advances in Veterinary Dermatology Vol 2. Oxford: Pergamon Press. 1993: 409-411