• Journal of Family Resource Management and Policy Review
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• v.7 no.1
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• pp.77-89
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• 2003

This study examines factors to influence consumers’reliability, and satisfactions for consumer anti-site, and willingness to visit that site again among consumers utilizing anti-sites. According to the results of this study, first, male, consumers utilizing electronic commerce were more likely to visit anti-site. Consumers were more likely to write their own message and reply other consumers’message in anti-site when they have purpose to complain about their dissatisfaction regarding the process of purchase behavior. Second, consumer's satisfaction is higher in cases of consumers having higher recognition of necessity of anti-site, visiting not required to affiliate the members of anti-site, and being reliable sites. Third, consumers were more likely to use anti-site again when they had higher recognition in the necessity of anti-site and were more satisfied. Finally, in order to facilitate the utilization of anti-sites, those solutions include systematic classification and management of writings listed in the site, active management of the site managers, solutions for criticisms on the writings listed and lack of objectivity of information provided, and active searches for solutions rather than listing of writings on discontents and resistance.

• Journal of Families and Better Life
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• v.25 no.4
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• pp.113-137
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• 2007

This study examined the characteristics of total consumers' anti-sites on on-line and their changes according to the establishment year of consumers' anti-sites, the activities and the evaluation of consumers' anti-sites and their differences according to the characteristics of consumers' anti-sites. Total 649 consumers' anti sites were analyzed for examining the characteristics of total consumers' anti-sites and 18 anti sites were selected for examining the activities and the evaluations of consumers' anti site. The anti sites were evaluated by the index of using in preceding research. The result showed that about 90% of total consumers' anti-site were not activated, only a few consumers participated even in the activated sites, most activity of the anti-site were operated only on on-line not off-line, over half of anti-sites targeted to the company in the type of the subject of anti-site, and the majority of the external shape of anti-site were cafe. On the change of characteristics according to the opening year, the proportion of cafe and the sites acting on both on-line and off-line were increased year by year. The number of anti-sites was decreased since 2005 and the proportion of highly activated sites was lowest in 2005. On the activity of anti-sites, the number of providing the information were more than the number of presenting the complaint among the bulletin writings. The number of the bulletin writing were more in highly activated sites than in low activated sites. most of highly activated sites were problem solving type compared to the low activated sites. The number of the bulletin writings in company anti-sites were the most among three type of subject of anti-site. The number of the bulletin writings in cafe type were more than in home-page type. On the evaluation of consumers' anti-sites, most of the sites didn't update the notices and provided incomplete information how consumers participated in the protesting movements. The highly activated sites functioned better in most parts in providing a information, connection with other consumer and site manager, management of the site.

• Journal of the Korean Home Economics Association
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• v.46 no.3
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• pp.103-116
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• 2008

With increasing of communication technology in cyber-space, the space of consumer complain behavior moved from off-line to on-line, so called anti-site. No researches, however, really have done how the anti-sites worked for promoting consumer rights through consumer complain behaviors in cyber space. The purpose of this research was to give some suggestions for activating anti-site for promoting consumer rights. For this purpose, questionnaire on-line survey was conducted from April, 12 to 24, 2004. And 143 samples, who were visiting anti-site during survey period, were selected. Main findings were as following: First, visitors had rather positive confidence with informations in anti-sites. Second, visitors thought that anti-sites were working rather well in implementing consumer movement by sharing their experiences, and by supporting complaining space in cyber. Visitors, however, thought that anti-sites were not working well as a space for companies, not by giving their attentions on consumers' complains. Third, the satisfaction level of visitors was found to be rather high in terms of informations in anti-sites, and to be rather low in terms of companies' attentions on anti-sites and management of anti-sites. Based on results, some suggestions of activating anti-site for promoting consumer rights were as following: First, visitors should not only get information, but support new and useful informations for others. And also it was suggested that visitors should join consumer movement through anti-site actively. Second, companies should pay attentions on anti-sites for their sake because anti-sites could give very useful information improving customer satisfaction, and finally reducing cost and increasing profit.

• Journal of the Korean Home Economics Association
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• v.41 no.1
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• pp.187-211
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• 2003

This study deals with activities in internet, including activities on consumer counseling, exchange of consumer information, and anti-sites. Among consumers having utilized those three types of internet sites, this study examines whether their satisfactions on them differ depending on their socio-demographic characteristics and types of activities and also explores which factors critically influence consumer satisfactions. According to the results of this study, consumers' satisfactions were higher when consumers evaluated counselors were objective, rapid, and reliable. Thus, Counselors must be more efficiently classify counseling contents, systematically manage, rapid, active and concrete answers for consumers applying for counseling. Second, in the case of consumer information site, the consumer satisfaction turns out to be positively related with exchange of consumer information, rapid provision of information, and reliability. Connection of relevant specialized information, encouragement of active information exchange among consumers, and objectivity and specialty in consumer information site are necessary to increase the quality of internet consumer information cite. Third, in the case of anti site, consumer satisfaction is higher in cases of consumer being joined in anti-site and in cases of objective and reliable sites. In order to facilitate the utilization of anti-sites, those solutions include systematic classification and management of writings listed in the site, active management of the site managers, reducing criticisms on the writings listed and objectivity of information provided, and active searches for solutions. Finally, in order to preserve consumer sovereignty, policy suggestions include improvements of service qualities provided in internet sites, active advertisement, improvement of site management through charging some fees for users, enhancing specialties.

• Korean Journal of Plant Resources
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• v.22 no.4
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• pp.312-316
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• 2009

In the present study, the anti-cancer activity of 80% ethanol extracts from 120 kinds of medicinal herbs and native plants were investigated. Among them, the barks of Melia azedarach L. var. japonica Makino showed the highest cytotoxicity in HCT-15 human colon cancer cell. With this result, we carried out hollow fiber (HF) assay and anti-metastasis study to confirm the anti-cancer effects of M. azedarach var. japonica. In MTT assay, M. azedarach var. japonica.inhibited the proliferation of HCT-15 cells in dose-dependent manner. HF assay was carried out using A549 human adenocarcinoma cell, HCT-15 and SK-Hep1 human liver cancer cell via intraperitoneal (IP) and subcutaneous (SC) site. As a results, SK-Hep1 implanted in IP site showed the highest cytotoxicity. The result from metastatic model using B16/BL6 mouse corresponded to that of HF assay. These results suggest that the ethanol extract from M. azedarach var. japonica. might have a potent anti-cancer activity and advanced study is needed for the development of novel natural anti-cancer drug.

• BMB Reports
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• v.30 no.5
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• pp.315-319
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• 1997

It was discovered that monoclonal anti-erythropoietin (EPO) antibody CFC-6 can neutralize EPO-induced cell activation. To know the binding site of CFC-6, recombinant human erythropoietin (rhEPO) was digested with Glu-C, followed by a separation using high performance liquid chromato graphy (HPLC). Each HPLC fraction was blotted on the nitrocellulose membrane and the membrane was treated with anti-EPO antibody CFC-6 and anti-mouse antibody which is modified with peroxidase. Only one spot showed the color and the fraction was sequenced by Edman degradation. The results suggest that CFC-6 recognizes amino acid sequence V63-W-Q-G-L-A-L-L-S-E72 which is a part of helix II of the EPO molecule. Binding of CFC-6 to EPO may inhibit EPO binding to its receptor, which implies that the antibody binding site and the receptor binding site are close or overlapping.

• Journal of Microbiology and Biotechnology
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• v.15 no.6
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• pp.1392-1396
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• 2005

Proteolytic digestion and CD measurement of wild-type and mutant cyclic AMP receptor proteins (CRPs) were performed either in the presence or absence of cyclic nucleotide. Results indicated that transition of a structural change to the hinge region by the binding of cAMP to the anti site was required for the binding of cAMP to the syn site near the hinge region and, although the occupancy of cAMP in the anti site increased the protein stability, CRP adopted more a stable conformation by the binding of cAMP to the syn site.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2008.10a
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• pp.736-739
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• 2008

Phishing is a form of online identity theft that aims to steal sensitive information such as online banking passwords and credit card information from users. This paper presents a novel browser extension, AntiPhish, that aims to protect users against spoofed web site-based phishing attacks. To this end, AntiPhish tracks the sensitive information of a user and generates warnings whenever the user attempts to give away this information to a web site today requires only the server to be hat is considered untrusted.

• Bulletin of the Korean Chemical Society
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• v.27 no.1
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• pp.59-64
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• 2006

Unlike other viral polymerases, HCV RNA-dependent RNA polymerase (RdRp) has not been successfully inhibited by nucleoside analogues presumably due to its strong substrate specificity for RNA. Thus, in order to understand the RNA-specificity of HCV RdRp, the structural characteristics of the active site was investigated. The hereto unknown 2-OH binding pocket at the active site of RdRp provides invaluable implication for the development of novel anti-HCV nucleoside analogues.

• Journal of Microbiology
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• v.42 no.4
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• pp.361-364
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• 2004

Internal ribosome entry site (IRES) of the hepatitis C virus (HCV) is known to be essential for HCV replication and most conserved among HCV variants. Hence, IRES RNA is a good therapeutic target for RNA-based inhibitors, such as ribozymes. We previously proposed a new anti-HCV modulation strategy based on trans-splicing ribozymes, which can selectively replace HCV transcripts with a new RNA that exerts anti-HCV activity. To explore this procedure, sites which are accessible to ribozymes in HCV IRES were previously determined by employing an RNA mapping method in vitro. In this study, we evaluate the intracellular accessibility of the ribozymes by comparing the trans-splicing activ­ities in cells of several ribozymes targeting different sites of the HCV IRES RNA. We assessed the intra­cellular activities of the ribozymes by monitoring their target-specific induction degree of both reporter gene activity and cytotoxin expression. The ribozyme capable of targeting the most accessible site iden­tified by the mapping studies then harbored the most active trans-splicing activity in cells. These results suggest that the target sites predicted to be accessible are truly the most accessible in the cells, and thus, could be applied to the development of various RNA-based anti-HCV therapies.