• Strategy21
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• 통권46호
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• pp.123-157
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• 2020

이번 연구는 국제해사국의 연례 보고서를 바탕으로 2009~2014년 동안 아프리카 인근 해역에서 발생한 771건의 해적사건을 음이항 회귀분석(Negative binomial regression)을 이용하여 분석했다. 이번 연구를 통해 소말리아 인근에서 작전하는 다국적 해군함정의 숫자가 증가할수록 소말리아 인근에서 발생하는 해적사건이 감소하는 사실을 정량적으로 확인했다. 이를 통해 청해부대를 비롯하여 소말리아 인근에서 실시되고 있는 다국적 해군의 대(對)해적 작전이 실제로 해적사건 감소에 효과가 있음을 증명했다.

• 한방재활의학과학회지
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• 제32권2호
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• pp.65-81
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• 2022

Objectives This study aimed to assess the effects of oral administration of deer antler extracts on an osteoporosis-induced animal model. We analyzed the results of using deer antler single extracts on animal models with osteoporosis through a systematic review and meta-analysis. Methods We included osteoporosis studies in animal experiments that administrated deer antler extracts orally. We searched the following 13 databases without a language restriction: PubMed, EMBASE, Cochrane Library, Cumulative Index to Nursing and Allied Health Literature (CINAHL), China National Knowledge Infrastructure (CNKI), Wanfang, Korean Medical Database (KMbase), National Digital Science Library (NDSL), Korean Traditional Knowledge (Koreantk), Oriental Medicine Advanced Searching Integrated System (OASIS), Research Information Sharing Service (RISS), Korea Institute of Science and Technology Information (KISTI), and Koreanstudies Information Service System (KISS). We used Systematic Review Centre for Laboratory Animal Experimentation's risk of bias tool for assessing the methodological quality of the included studies. Results A total of 299 potentially relevant studies were searched and 11 were included for a systematic review. Nine studies used a single deer antler extract. A study compared the effects of single extracts of deer antler and antler glue, while another study compared the effects of three single extracts of deer antler, old antler, and antler glue. For evaluating the intervention effect, bone mineral density (BMD) was measured as the primary outcome, while the histomorphometric indicators of the bone and serum alkaline phosphatase and osteocalcin levels were used as the secondary outcome variables. On conducting a meta-analysis of studies on single deer antler extract, BMD was observed to be significantly increased compared to that in control group (standardized mean difference [SMD]=2.11; 95% confidence interval [CI]=1.58~2.65; Z=7.75; p<0.00001; I²=56%). As a result of meta-analysis, according to the concentration of deer antler, the group with high concentration showed statistically significantly higher BMD than the group with low concentration (SMD=1.28; 95% CI=0.74~1.82; Z=4.63; p<0.00001; I²=9%). Conclusions The research shows that the deer antler extracts have significant anti-osteoporotic effects on the osteoporosis-induced animal model. However the studies included in this research had a high methodological risk of bias. This indicates the requirement of considerable attention in the interpretation of the study results.

• Restorative Dentistry and Endodontics
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• 제48권4호
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• pp.39.1-39.23
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• 2023

Objectives: This study aimed to investigate the effectiveness of different topical/systemic agents in reducing the damage caused by bleaching gel to pulp tissue or cells. Materials and Methods: Electronic searches were performed in July 2023. In vivo and in vitro studies evaluating the effects of different topical or systemic agents on pulp inflammation or cytotoxicity after exposure to bleaching agents were included. The risk of bias was assessed. Results: Out of 1,112 articles, 27 were included. Nine animal studies evaluated remineralizing/anti-inflammatories agents in rat molars subjected to bleaching with 35%-38% hydrogen peroxide (HP). Five of these studies demonstrated a significant reduction in inflammation caused by HP when combined with bioglass or MI Paste Plus (GC America), or following KF-desensitizing or Otosporin treatment (n = 3). However, orally administered drugs did not reduce pulp inflammation (n = 4). Cytotoxicity (n = 17) was primarily assessed using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay on human dental pulp cells and mouse dental papilla Cell-23 cells. Certain substances, including sodium ascorbate, butein, manganese chloride, and peroxidase, were found to reduce cytotoxicity, particularly when applied prior to bleaching. The risk of bias was high in animal studies and low in laboratory studies. Conclusions: Few in vivo studies have evaluated agents to reduce the damage caused by bleaching gel to pulp tissue. Within the limitations of these studies, it was found that topical agents were effective in reducing pulp inflammation in animals and cytotoxicity. Further analyses with human pulp are required to substantiate these findings.

• 대한약침학회지
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• 제27권1호
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• pp.14-20
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• 2024

Objectives: Frozen shoulder (FS) is one of the most challenging shoulder disorders for patients and clinicians. Its symptoms mainly include any combination of stiffness, nocturnal pain, and limitation of active and passive glenohumeral joint movement. Conventional treatment options for FS are physical therapy, nonsteroidal anti-inflammatory drugs, injection therapy, and arthroscopic capsular release, but adverse and limited effects continue to present problems. As a result, pharmacoacupuncture (PA) is getting attention as an alternative therapy for patients with FS. PA is a new form of acupuncture treatment in traditional Korean medicine (TKM) that is mainly used for musculoskeletal diseases. It has similarity and specificity compared to corticosteroid injection and hydrodilatation, making it a potential alternative injection therapy for FS. However, no systematic reviews investigating the utilization of PA for FS have been published. Therefore, this review aims to standardize the clinical use of PA for FS and validate its therapeutic effect. Methods: The protocol was registered in Prospero (CRD42023445708) on 18 July 2023. Until Aug. 31, 2023, seven electronic databases will be searched for randomized controlled trials of PA for FS. Authors will be contacted, and manual searches will also be performed. Two reviewers will independently screen and collect data from retrieved articles according to predefined criteria. The primary outcome will be pain intensity, and secondary outcomes will be effective rate, Constant-Murley Score, Shoulder Pain and Disability Index, range of motion, quality of life, and adverse events. Bias and quality of the included trials will be assessed using the Cochrane handbook's risk-of-bias tool for randomized trials. Meta analyses will be conducted using Review Manager V.5.3 software. GRADE will be used to evaluate the level of evidence for each outcome. Results: This systematic review and meta-analysis will be conducted following PRISMA statement. The results will be published in a peer-reviewed journal. Conclusion: This review will provide scientific evidence to support health insurance policy as well as the standardization of PA in clinical practice.

• 한국콘텐츠학회논문지
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• 제17권11호
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• pp.554-566
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• 2017

우리나라는 방송법 등을 통해 방송이 특정정당이나 후보자에 대해 정치적 중립을 유지하도록 하고 있다. 그러나 박근혜 대통령 탄핵과 관련해 MBC와 JTBC는 보수와 진보로 양분돼 보도함으로써 공정성에 대한 논란이 일었다. 이러한 논란을 실증적으로 살펴보기 위해 탄핵이 인용된 날부터 일주일간 양 방송사의 저녁종합뉴스의 아이템 수 변화, 주제의 편향성, 뉴스 프레임을 등 3가지 측면을 분석하였다. 연구결과 JTBC와 MBC의 관련 보도는 양적으로 현저한 차이를 보였고, JTBC는 촛불집회 쪽에, MBC는 태극기집회 쪽 관련 주제를 집중적으로 보도했다. 뉴스 프레임 측면에서 MBC는 탄핵인용 관련 보도에서 박근혜 대통령과 이를 옹호하는 태극기집회 참여자들 쪽에서, JTBC는 반대로 반 박근혜 대통령과 탄핵의 정당성을 주장하는 촛불집회 참여자 입장에서 보도한 것으로 나타났다.

• 대한한의학회지
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• 제38권1호
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• pp.93-111
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• 2017

Objectives: The aim of this study is to make evidence-based data for developing a traditional Korean medicine clinical practice guideline for acute bronchitis. Methods: We searched 3 international databases(PubMed, EMBASE, CENTRAL) and 7 domestic databases (KoreaMed, Kmbase, NDSL, KISS, KISTI, OASIS, KoreaTK) to identify randomized controlled trials (RCTs) of acute bronchitis using medicine in recent 10 years. The chosen trials were analyzed by their study design, age range, intervention group, control group, primary and second outcome measure, inclusion and exclusion of participants and adverse events. Results: 15 RCTs are finally included in this study and most of their medications are herbal medicine. For diagnosis and outcome measure of acute bronchitis, Bronchitis Severity Score(BSS) was mostly used. Other measurements eligible are coughing fits, quality of life scale, sputum viscosity, change of individual symptoms and patient's satisfaction. Test duration was for average 7days and safety assessment was held by recording adverse events. Except for anti-inflammatory and antibiotic trials, all medications are found to be effective and well-tolerated. General risk of bias of chosen trials is evaluated low. Conclusions: A well designed clinical trials for traditional Korean medicine of acute bronchitis is needed and this study is expected to make it available.

• 전자공학회논문지D
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• 제36D권7호
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• pp.66-79
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• 1999

본 논문에서는 얕은 양자 우물(extremely shaliow quantum wells, ESQWs)을 사용한 광 쌍안정 대칭형 자기 전광 소자(symmetric self elctrooptic effect device, S-SEED)의 성능에 있어서 높은 입사 광전력의 영향을 조사한다 . 다음과 같은 네 가지 ESQWs S-SEED 구조를 고려하였다. 무 반사 입힘(AR-coated) ESQWs S-SEED, back-to-back ARcoated ESQWs S-SEED, 비대칭 공명구조(AFP) ESQWs S-SEED, back-toback AFP ESQWs S-SEED. 입사 광 전력이 증가함에 따라 On/Off 대조비, On/Off 반사율 차이와 같은 소자성능은 ohmic heating 과 여기자 포화(exciton saturation)의 영향으로 심각하지 않게 저하된다. 한편 소자의 스위칭 속도는 지속적으로 증가하다가 특정 입사 광 전력 하에서 점차 감소하기 시작한다. 직렬 광 연결 시스템(cascading optical interconnection system)에 있어서 소자의 최대 속도 스위칭 동작을 위한 최대 입사 광 전력의 최적화를 바탕으로 0 V와 5 V의 외부 전압 조건에서 양자우물의 수를 변화시키면서 $5{\times}5{\mu}m^2$의 mesa 영역에 대하여 네 가지 ESQWs S-SEED의 시스템 비트 레이트를 모의 실험하고 그 결과를 분석하였다.

• 한국전자파학회논문지
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• 제16권11호
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• pp.1106-1113
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• 2005

본 논문에서는 단일 국부 발진기를 이용하여 IEEE 802.11a/b/g 표준의 두 대역 신호를 처리할 수 있는 이중 대역 혼합기를 설계 구현하여 기존 방식의 단점을 개선하였다. 기존 회로 구조는 두 대역을 처리하기 위해 각각 두 개의 국부 발진기와 혼합기를 사용함으로 인하여 구조의 복잡함과 큰 전력 손실이라는 단점을 가지고 있었다. 구현된 회로는 입력 RF 2.452/5.260 GHz에서 동일한 IF인 356 MHz로 하향 변환하였을 때 변환 손실은 각각 11.6 dB, 16.8 dB, IIP3(Input 3rd Intercept Point)는 각각 8.77 dBm, 12.5 dBm으로 측정되었으며, RF-LO 격리도는 각각 36 dB, 41 dB, LO-IF 격리도는 각각 50 dB 이상의 특성을 나타내었다.

• 대한한방부인과학회지
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• 제31권4호
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• pp.39-53
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• 2018

Objectives: The purpose of this review was to overview and evaluate the efficacy of electroacupunture for women with polycystic ovarian syndrome (PCOS) Methods: Relevant randomized controlled studies (RCTs) were identified by database searches in PubMED, EMBASE, OASIS, and Google scholar, up to May 2018. Data were extracted regarding hyperandrogenism, obesity and hyperinsulinemia indices. The risk of bias was assessed. Results: Five RCTs were included for analysis. In one RCT, electroacupuncture group had significantly lower free testosterone and testosterone, compared to no treatment group. However, The other RCTs showed no significant difference between two groups. For LH/FSH, Ferriman Gallway score, anti-mullerian hormone, body mass index, weight and waist, and insulin, electroacupuncture group showed no significant difference, compared to physical exercise, no treatment, and sham acupuncture group. Conclusions: Only a limited number of RCTs have been reported. At present, there is insufficient evidence to support the use of electroacupuncture for treatment of PCOS.

• 대한원격탐사학회지
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• 제31권6호
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• pp.583-598
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• 2015

본 연구에서는 천리안위성 기반의 지표면 열적 특성 감시 및 기상현상 탐지에 이용할 수 있는 배경 온도장을 산출하고 지상관측자료 및 지리정보와 비교하여 정확도를 검증하였다. 배경온도장은 밝기온도를 선택하였으며 2012년 자료를 이용하여 월별로 매 시간대에 대해 산출되었다. 밝기온도 자료에서 청천화소와 구름화소를 구별하기 위해 천리안 구름탐지를 사용하였고, 천리안 구름탐지의 입력자료로 사용된 수치모델자료와 공간 균질성 검사 부분에서 구름 오탐지현상을 발견하였다. 과다하게 구름으로 오탐지된 화소는 통계적인 방법에 기반한 구름화소 복원을 통해 해결하였다. 산출된 밝기온도 배경장은 지상관측 기온과 0.95의 상관관계를 보였으며 0.66 K의 편향과 4.88 K의 평균 제곱근 오차를 보였다. 밝기온도 배경장과 고도는 시간대와 계절에 따라 변동성을 보이는 음의 상관관계를 보였다. 녹지와의 상관관계는 기온이 높은 계절 및 주간에 높게 나타났으며, 상관관계의 시간에 따른 변화가 관측되었다. 이러한 이유로 지표면온도 산출 시 시간에 따른 방출률을 별도로 구성해야 할 필요성이 제기되었다.