• Asian Pacific Journal of Cancer Prevention
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• v.16 no.17
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• pp.8017-8018
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• 2015

• Journal of Haehwa Medicine
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• v.5 no.2
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• pp.445-448
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• 1997

The human anatomy is the fundamental subject which is required lots of time and efforts for medical students. But most of the oriental medical students think it little important field. And moreover they have no active attitudes in their courses. In order to improve the present situation, the results obtained from this study are as follows: 1. As a Law of Cadaver Conservation revised systemically, there's need to have enough cadavers for dissection. 2. The teaching method must be converted into the laboratory technique with the strengthening human anatomy. 3. With opening a neuroanatomy course in oriental medical curriculum, the quality of nervous system is expected to increase. 4. Under the current medical system, there's need to have discussion deeply about the histology course.

• Proceedings of the Zoological Society Korea Conference
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• 2003.08a
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• pp.172.4-172
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• 2003

No Abstract, See Full Text

• The Journal of Korean Physical Therapy
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• v.14 no.2
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• pp.86-97
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• 2002

To evaluate the fields of human anatomy and physiology important in clinical practice of physical therapy, a questionnaire survey was performed for 70 physical therapists who were practicing in general hospitals, clinics, public health centers, and rehabilitation centers in several provinces including Seoul and Chungcheongdo. Fields of anatomy and physiology were divided into 13 chapters and subdivided into 52 items. And the preferred ranks were statistically analysed according to the career of physical therapists, nature of the institute and the post of duty. As results joint system, muscular system, skeletal system and nervous system were ranked in the fields of great importance. The relative importance of practical knowledge in anatomy and physiology should be considered in educating students as well as reeducation of practitioners.

• Journal of Oral Medicine and Pain
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• v.18 no.2
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• pp.131-147
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• 1993

To evaluate the contribution of head/neck posture to signs/symptoms of craniomandibular disorder(CMD), the author clinically, cephalo-metrically, analyzed craniomandibular index (CMI), clinical dysfunction index(CDI), occlusal index(OI) and head posture, cervical spine, cervicovertebral anatomy, craniofacial variables from 30 CMD patients and control. And the author analyzed difference between patients and control, and the correlation between CMI, CDI and head posture, cervical spine, cervicovertebral anatomy, craniofacial variables in CMD patients and control. The obtained results were as follows : 1. There was very high significant correlation between CMI and CDI(r=0.8969, p<0.01). 2. There was significant difference between patients and control in head/neck posture, head/neck anatomy(p<0.05). 3. There was significant correlation between CMI, CDI and head posture, cervical spine, cervicovertebral anatomy, craniofacial variables(p<0.05). 4. There was more significant correlation between DI and head/neck posture, head/neck anatomy than between PI and head/neck posture, head/neck anatomy in CMD patients(p<0.05)

• Animal cells and systems
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• v.15 no.4
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• pp.268-273
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• 2011

Transgenic mice expressing green fluorescent protein (GFP) under the control of human glial fibrillary acidic protein promoter (hGFAP) have been utilized for in vivo labeling of astrocytes. Although it has been considered that virtually all astrocytes express GFP in this transgenic mouse, we found that different subsets of GFAP-expressing astrocytes express considerably different levels of GFP in the adult brain. Astrocytes in the spinal cord, the molecular layer of thecerebellum, meninges, white matter, corpus callosum and blood vessels exhibited strong GFP, whereas subsets of astrocytes associated with granule cells in the cerebellum and dentate gyrus did not or only marginally exhibited GFP. We also found that a small subset of GFP-expressing cells in the periglomeruli of the olfactory bulb did not express GFAP immunoreactivity. Collectively, these results suggest that human GFAP promoter-derived GFP expression does not faithfully recapitulate the endogenous GFAP expression in mice, suggesting that upstream regulatory mechanisms controlling GFAP transcription are different in different populations of astrocytes, and may reflect the functional diversity of astrocytes.

• International Journal of Oral Biology
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• v.31 no.3
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• pp.73-79
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• 2006

Tissue stem cells are used for the regenerative medicine. In previous study we observed hard tissue formation of human dental pulp-derived cells using alginate scaffold. In this study, we explore the ability to differentiate of the 13th passage cells with glycerol 2-phosphate disodium salt hydrate (${\beta}-GP$) which accelerate calcification. Reverse transcriptase Polymerase Chain Reaction (RT-PCR), transplants using alginate scaffold and histological examination were performed. We observed the expression of DSPP mRNA on day 10 cultured cells with ${\beta}-GP$. In conclusion, the 13th passage cells still have an ability to differentiate into odontoblast-like cells and alginate supports the differentiation of cultured cells in the transplants.

• BMB Reports
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• v.47 no.10
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• pp.581-586
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• 2014

Epidermal growth factor (EGF) is known to play key roles in skin regeneration and wound-healing. Here, we demonstrate that Pep2-YAC, a tripeptide covering residues 29-31 in the B loop of EGF, promotes the proliferation of HaCaT keratinocytes with activity comparable to EGF. The treatment of HaCaT cells with Pep2-YAC induced phosphorylation, internalization, and degradation of EGFR and organization of signaling complexes, which consist of Grb2, Gab1, SHP2, and PI3K. In addition, it stimulated the phosphorylation of ERK1/2 at Thr 202/Tyr 204 and of Akt1 at Ser 473 and the nuclear translocation of EGFR, STAT3, c-Jun, and c-Fos. These results suggest that Pep2-YAC may be useful as a therapeutic agent for skin regeneration and wound-healing as an EGFR agonist.

• Anatomy and Cell Biology
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• v.51 no.4
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• pp.284-291
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• 2018

The role of androgens in the development of cardiovascular diseases remains controversial. The current study therefore sought to determine the changes in the histomorphology of the common carotid artery of the male rat in orchidectomy-induced hypogonadism. Twenty-two Rattus norvegicus male rats aged 2 months were used. The rats were randomly assigned into baseline (n=4), experimental (n=9), and control (n=9) groups. Hypogonadism was surgically induced in the experimental group by bilateral orchiectomy under local anesthesia. At experiment weeks 3, 6, and 9, three rats from each group (experimental and control) were euthanized, their common carotid artery harvested, and routine processing was done for paraffin embedding, sectioning, and staining. The photomicrographs were taken using a digital photomicroscope for morphometric analysis. Orchidectomy resulted in the development of vascular fibrosis, with a significant increase in collagen fiber density and decrease in smooth muscle and elastic fiber density. Moreover, there was development of intimal hyperplasia, with fragmentation of medial elastic lamellae in the common carotid artery of the castrated rats. Orchidectomy induces adverse changes in structure of the common carotid artery of the male rat. These changes may impair vascular function, therefore constituting a possible structural basis for the higher incidences of cardiovascular diseases observed in hypogonadism.

• Journal of Korean Academy of Rural Health Nursing
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• v.18 no.1
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• pp.49-57
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• 2023

Purpose: This study was conducted to confirm the usability of virtual reality-based anatomy education programs for nursing college students and to identify factors that affect their usability. Methods: Data were collected from 143 nursing college students in Gyeonggi-do using a structured questionnaire from May to June 2022. The data analysis was analyzed using real numbers, percentages, means and standard deviation, ANOVA, Scheff's test, Pearson's correlation, and multiple regression using the SPSS/WIN 23.0 program. Results: The subject's usability was 4.26 points (out of 5). The variable that has the greatest influence on the usability of virtual reality-based anatomy education programs is perceived innovation (β=.370, p<.001), followed by perceived pleasure (β=.295, p=.001), perceived ease (β=.253, p<.001), smartphone usage time per day (β=.102, p=.031). These variables explained 70.6% of the usability of virtual reality-based anatomy education programs. Conclusion: The results of this study can be utilized as basic data for a virtual reality-based anatomy education program that will be developed and applied to nursing students in the future.