• Molecular & Cellular Toxicology
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• v.1 no.1
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• pp.17-25
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• 2005

There are some critical drawbacks in the use of biomarkers for a global assessment of the toxicological impacts many chemicals and environmental pollutants have, primarily due to an individual biomarker's specificity for an explicit chemical or toxicant. In other words, the biomarker-based assessment methodology used to analyze toxicological effects lacks a high-throughput capability. Therefore, eco-toxicogenomics, or the study of toxicogenomics with organisms present within a given environmental locale, has recently been introduced with the advent of the so-called "-omics" era, which began with the creation of microarray technologies. Fish are comparable with humans in their toxicological responses and thus data from toxicogenomic studies performed with fish could be applied, with appropriate tools and implementation protocols, to the evaluation of environments where human or animal health is of concern. At present, there have been very active research streams for developing expression sequence tag (EST) databases (DBs) for zebra fish and rainbow trout. Even though few reports involve toxicogenomic studies with fish, a few groups have successfully fabricated and used cDNA microarrays or oligo DNA chips when studying the toxicological impacts of hypoxia or some toxicants with fish. Furthermore, it is strongly believed that this technology can also be implemented with non-model fish. With the standardization of DNA microarray technologies and ample progress in bioinformatics and proteomic technologies, data obtained from DNA microarray technologies offer not only multiple biomarker assays or an analysis of gene expression profiles, but also a means of elucidating gene networking, gene-gene relations, chemical-gene interactions, and chemical-chemical relationships. Accordingly, the ultimate target of eco-toxicogenomics should be to predict and map the pathways of stress propagation within an organism and to analyze stress networking.

• Proceedings of the Korean Society of Crop Science Conference
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• 2017.06a
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• pp.146-146
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• 2017

The pod shattering or dehiscence is essential for the propagation of pod-bearing plant species in the wild, but it causes significant yield losses during harvest of domesticated crop plants. Identifying novel molecular makers, which are linked to seed-shattering genes, is needed to employ the molecular marker-assisted selection for efficiently developing shattering-resistant soybean varieties. In this study, a genetic linkage map was constructed using 115 recombinant inbred lines (RILs) developed from crosses between the pod shattering susceptible variety, Keunol, and resistant variety, Sinpaldal. A 180 K Axiom(R) SoyaSNPs data and pod shattering data from two environments in 2001 and 2015 were used to identify quantitative trait loci (QTL) for pod shattering. A major QTL was identified between two flanking single nucleotide polymorphism (SNP) markers, AX-90320801 and AX-90306327 on chromosome 16 with 1.3 cM interval, 857 kb of physical range. In sequence, genotype distribution analysis was conducted using extreme phenotype RILs. This could narrow down the QTL down to 153 kb on the physical map and was designated as qPDH1-KS with 6 annotated gene models. All exons within qPDH1-KS were sequenced and the 6 polymorphic SNPs affecting the amino acid sequence were identified. To develop universally available molecular markers, 38 Korean soybean cultivars were investigated by the association study using the 6 identified SNPs. Only two SNPswere strongly associated with the pod shattering. These two identified SNPs will help to identify the pod shattering responsible gene and to develop pod shattering-resistant soybean plants using marker-assisted selection.

• Earthquakes and Structures
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• v.20 no.1
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• pp.71-86
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• 2021

This paper focuses on the development and assessment of the expected damage for the rocking response of rigid anchored blocks, with irregular geometry and non-uniform mass distribution, considering the site conditions and the seismicity of Mexico City. The non-linear behavior of the restrainers is incorporated to evaluate the pure tension and tension-shear failure mechanisms. A probabilistic framework is performed covering a wide range of block sizes, slenderness ratios and eccentricities using physics-based ground motion simulation. In order to incorporate the uncertainties related to the propagation of far-field earthquakes with a significant contribution to the seismic hazard at study sites, it was simulated a set of scenarios using a stochastic summation methods of small-earthquakes records, considered as Empirical Green's Function (EGFs). As Engineering Demand Parameter (EDP), the absolute value of the maximum block rotation normalized by the body slenderness, as a function of the peak ground acceleration (PGA) is adopted. The results show that anchorages are more efficient for blocks with slenderness ratio between two and three, while slenderness above four provide a better stability when they are not restrained. Besides, there is a range of peak intensities where anchored blocks located in soft soils are less vulnerable with respect to those located in firm soils. The procedure used in here allows to take decisions about risk, reliability and resilience assessment of different types of contents, and it is easily adaptable to other seismic environments.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.11 no.12
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• pp.2233-2240
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• 2007

This paper presents the measured path loss exponents and standard deviations using measured data at 60GHz to analyze the propagation characteristics of millimeter wave bands having great demand for picocellular communications. In addition the angle of arrival(AOA) were measured to analyze the arrival direction of muitipath waves affecting the received signal strength. As results of analysis, the pathloss exponents in each environment are found to be lower than 2 for free space pathloss exponent. They were determined with the qualities of bottom materials affecting signal strength. The angles of arrival by multipath waves were different with the circumference structures between transmitter and receiver. That is, the multipath waves excluding direct and ground reflected wave were difficult to find in wide space such a gymnasium and playground, however the wall multipath waves were found to arrive at receiver in the corridor. The multipath waves at 60GHz can be known to hardly affect to the received signal strength because of weak signals compared with direct wave.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.40 no.5
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• pp.791-798
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• 2015

It has been grown interests of the convergence technologies about communication systems and vehicular industry. Vehicular communications enable a number of infotainment applications to serve cars under high mobility environments. To achieve this goal, a robust and accurate channel estimation scheme is of great importance. This paper proposes an enhanced Decision-Directed channel estimation scheme called PTAU(Pilot Tone Aided Update) for IEEE 802.11p in vehicular communication environment. Existing approaches which use subsequent data symbols to estimate channel response in time domain will lead to the error propagation. In this paper, we use the pilot subcarriers to get initial channel response, then utilize the correlation characteristics to update channel response in frequency domain. Finally, Analysis and simulation results reveal that the proposed scheme outperforms in bit error rate(BER), significantly improve the performance of the estimation.

• Journal of the Institute of Convergence Signal Processing
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• v.24 no.2
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• pp.112-118
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• 2023

Internet of Things(IoT) technology is developing to a stage where the Internet and objects are connected and objects themselves analyze and judge data to interconnect the real world and the virtual world in real time. This technology consists of sensors, actuators, devices, and networks, and it is being applied in various fields. As the number of IoT devices and applications increases, data traffic also increases. In this paper, a messaging system is designed and implemented in order to analyze the performance between an IoT device and MQTT broker. The experimental was performed to measure MQTT-based round-trip time and message transmission time between the IoT device and the broker. The result shows that there is no packet loss, and propagation delay affects round-trip time.

• Korean Journal of Clinical Laboratory Science
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• v.53 no.1
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• pp.11-18
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• 2021

Respiratory viruses (RVs) cause infections in hospital environments through direct contact with infected visitors. In infection control, it causes major problems of acquired infections in hospitals by respiratory viruses. The surveillance data derived from clinical laboratories are often used to properly allocate medical resources to hospitals and communities for treatment, consumables, and diagnostic product purchases in the institutions and public health sectors that provide health care. An early diagnosis is essential in infection with respiratory viruses, and methods that can be used in diagnostic methods using respiratory samples include virus culture, molecular diagnosis, and analysis. A microchip provides a new strategy for developing a more diverse and powerful technology called point-of-care testing. The importance of the respiratory system should be applied strictly to the infection control guidelines to ensure the occupational health and safety of health care workers. Evidence of clinical efficacy, including this study, is challenging the long-standing paradigm for infection propagation. Additional assistance will be needed for frequent tests to detect respiratory viruses in inpatients who have begun to show new respiratory symptoms indicating infections requiring efforts to control the infection.

• Journal of Advanced Navigation Technology
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• v.27 no.4
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• pp.410-416
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• 2023

Unlike geostationary satellite communication systems, low-earth orbit(LEO) satellite communication systems move at relatively high speeds, and the angle with the ground device is not fixed and varies over a wide range. The propagation channel condition between satellites and ground nodes cannot be assumed line of sight(LOS) anymore. This paper analyzes the low-orbit multi-path fading satellite channel model that can occur in LEO satellite communication systems and Doppler frequency transition caused by high-speed maneuvering of LEO satellites and presents effective equalization techniques for OFDM and SC-FDE transmission methods suitable for multi-path frequency selective fading satellite channel models. In addition, this paper compares and analyzes the performance of OFDM and SC-FDE transmission methods in multipath fading LEO satellite channel environment using the proposed equalization techniques through simulations. Simulation results showed that SC-FDE outpeformed OFDM.

• Journal of Korea Multimedia Society
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• v.14 no.2
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• pp.258-268
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• 2011

Underwater acoustic sensor networks can be used disaster prevention and environmental monitoring systems in underwater environments. Because, the underwater environment is different from the ground, the long propagation delay, low transfer rates and limited bandwidth characteristics should be considered. In this, paper will propose the MAC protocol that allocates time slot into each node according to priority policy through the period of contention-free slot reservation in underwater acoustic sensor networks in order to avoid collision and minimize energy consumption waste. We perform mathematical analysis to evaluate the performance of the proposed protocol with regard to the collision probability, the energy consumption by collision, throughput and channel utilization. We compare the proposed protocol with the conventional protocol, and the performance results show that the proposed protocol outperforms the conventional protocol.

• The Journal of the Acoustical Society of Korea
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• v.28 no.4
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• pp.318-327
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• 2009

In this paper, we propose a 3-D geometric localization method for near-field broadband source in shallow water environments. According to the waveguide invariant theory, slope of the interference pattern which is seen in a sensor spectrogram directly proportional to a range of the source. The relative ratio of the range between source and sensors was estimated by matching of two interference patterns in spectrogram. Then this ratio is applied to the Apollonius's circle which shows the locus of a source whose range ratio from two sensors is constant. Two Apollonius's circles from three sensors make the intersection point that means the horizontal range and the azimuth angle of the source. And this intersection point is constant with source depth. Therefore the source depth can be estimated using 3-D hyperboloid equation whose range difference from two sensors is constant. To evaluate a performance of the proposed localization algorithm, simulation is performed using acoustic propagation program and analysis of localization error is demonstrated. From simulation results, error estimate for range and depth is described within 50 m and 15 m respectively.