• Title/Summary/Keyword: analysis and modeling

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Trajectories of Mothers' Perceived Marital Conflict and its Relationship to Depression and Children' School Readiness, Self-esteem, and Happiness (어머니가 지각한 부부갈등 변화 양상에 따른 우울 및 자녀의 학교준비도, 자아존중감, 행복감 차이)

  • Yeon, Eun Mo;Choi, Hyo-Sik
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.21 no.5
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    • pp.344-352
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    • 2020
  • The purpose of this study was to identify the latent classes in the changing patterns of marital conflict perceived by mothers to explore its relationship with the changing patterns of mothers' depression, school readiness, self-esteem, and happiness of their children five years after their birth. A total of 1,243 responses from the 1st (2008) to 5th (2012) and 7th (2014) to 10th (2017) Korean Child and Youth Panel Study(KCYPS) were analyzed by Latent Growth Modeling (LGM) and Growth Mixture Analysis (GMA). The results were as follows. First, three changing patterns in the mothers' perceived marital conflict groups were identified: low-low changing, average-uptrend, and high-unchanging group. Second, an increasing pattern of depression was found from mothers of high-unchanging group over five years. Third, school readiness for their children was differentiated according to the latent classes. In particular, children from the low-low changing group showed higher readiness as well as self-esteem and happiness. Fourth, children from mothers of the low-low changing group showed high self-esteem and happiness in lower grades in elementary school. The results of this study suggest that the mothers' perceived marital conflict had an influence on themselves as well as their children's school related behaviors. Suggestions for an intervention program to resolve marital conflict are also discussed.

Flow Calibration and Validation of Daechung Lake Watershed, Korea Using SWAT-CUP (SWAT-CUP을 이용한 대청호 유역 장기 유출 유량 보정 및 검증)

  • Lee, Eun-Hyoung;Seo, Dong-Il
    • Journal of Korea Water Resources Association
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    • v.44 no.9
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    • pp.711-720
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    • 2011
  • SWAT (Soil and Water Assessment Tool) model was calibrated for the flow rate of the Deachung lake with a large area of 3108.29 $km^2$. Application of SWAT model requires significant number of input data and is prone to result in uncertainties due to errors in input data, model structure and model parameters. The SUFI-2 (Sequential Uncertainty Fitting Ver. 2) program and GLUE (Generalized Likelihood Uncertainty Estimation) program in SWAT-CUP (SWAT-Calibration and Uncertainty Program) are used to select the best parameters for SWAT model. Optimal combination of parameter values was determined through 2,000 iterative SWAT model runs. The Nash-Sutcliffe values and $R^2$ values were 0.87 and 0.89 respectively indicating both methods show good agreements with observed data successfully. RMSE and MSE values also showed similar results for both programs. It seems the SWAT-CUP has a great practical appeal for parameter optimization especially for large basin area and it also can be used for less experienced SWAT model users.

A Novel Suberoylanilide Hydroxamic Acid Histone Deacetylase Inhibitor Derivative, N25, Exhibiting Improved Antitumor Activity in both Human U251 and H460 Cells

  • Zhang, Song;Huang, Wei-Bin;Wu, Li;Wang, Lai-You;Ye, Lian-Bao;Feng, Bing-Hong
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.10
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    • pp.4331-4338
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    • 2014
  • $N^1$-(2, 5-dimethoxyphenyl)-$N^8$-hydroxyoctanediamide (N25) is a novel SAHA cap derivative of HDACi, with a patent (No. CN 103159646). This invention is a hydroxamic acid compound with a structural formula of $RNHCO(CH_2)6CONHOH$ (wherein R=2, 5dimethoxyaniline), a pharmaceutically acceptable salt which is soluble. In the present study, we investigated the effects of N25 with regard to drug distribution and molecular docking, and anti-proliferation, apoptosis, cell cycling, and $LD_{50}$. First, we designed a molecular approach for modeling selected SAHA derivatives based on available structural information regarding human HDAC8 in complex with SAHA (PDB code 1T69). N25 was found to be stabilized by direct interaction with the HDAC8. Anti-proliferative activity was observed in human glioma U251, U87, T98G cells and human lung cancer H460, A549, H1299 cells at moderate concentrations ($0.5-30{\mu}M$). Compared with SAHA, N25 displayed an increased antitumor activity in U251 and H460 cells. We further analyzed cell death mechanisms activated by N25 in U251 and H460 cells. N25 significantly increased acetylation of Histone 3 and inhibited HDAC4. On RT-PCR analysis, N25 increased the mRNA levels of p21, however, decreased the levels of p53. These resulted in promotion of apoptosis, inducing G0/G1 arrest in U251 cells and G2/M arrest in H460 cells in a time-dependent and dose-dependent manner. In addition, N25 was able to distribute to brain tissue through the blood-brain barrier of mice ($LD_{50}$: 240.840mg/kg). In conclusion, our findings demonstrate that N25 will provide an invaluable tool to investigate the molecular mechanism with potential chemotherapeutic value in several malignancies, especially human glioma.

The Analysis of Relationships among Self-Handicapping Tendency, Goal Orientation, Self-Efficacy and Learning Strategies in Chemistry Education (화학교과에서 자아핸디캡경향, 목표지향성, 자기효능감 및 학습전략 사이의 관계분석)

  • Ko, Young-Chun
    • Journal of the Korean Chemical Society
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    • v.51 no.5
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    • pp.459-470
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    • 2007
  • The structural equation modeling techniques were used to assess a model of chemistry learning strategy based on self-handicapping tendency and goal orientation. Data were collected during chemistry lessons in two high schools. In the optimal model II-2 of this research, the self-handicapping tendency was negatively related to the use of self-efficacy. The learning goal was positively related to the use of self-efficacy and to learning strategy. The performance- approach goal was positively related to self-efficacy but presented an negative relationship to learning strategy. The performance-avoidance goal was negatively related to self-efficacy but presented an positive relationship to learning strategy. Besides affecting the learning strategy through self-efficacy indirectly, the learning goal, performance-approach goal, and performance-avoidance goal affected learning strategy directly. The self-handicapping tendency and performance- avoidance goal were a negative predictors of self-efficacy, but the learning goal and performance-approach goal were a positive predictors. And the self-efficacy affected learning strategy positively. The implications of these findings for learning strategy in chemistry are discussed. Although the paths model of relationships of the motivations to learn and learning strategies in chemistry education as mentioned above is established, the more systematic search for the higher self-efficacy and learning strategy in different courses and curriculums may be needed.

Novel Intensity-Based Fiber Optic Vibration Sensor Using Mass-Spring Structure (질량-스프링 구조를 이용한 새로운 광세기 기반 광섬유 진동센서)

  • Yi, Hao;Kim, Hyeon-Ho;Choi, Sang-Jin;Pan, Jae-Kyung
    • Journal of the Institute of Electronics and Information Engineers
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    • v.51 no.6
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    • pp.78-86
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    • 2014
  • In this paper, a novel intensity-based fiber optic vibration sensor using a mass-spring structure, which consists of four serpentine flexure springs and a rectangular aperture within a proof mass, is proposed and its feasibility test is given by the simulation and experiment. An optical collimator is used to broaden the beam which is modulated by the displacement of the rectangular aperture within the proof mass. The proposed fiber optic vibration sensor has been analyzed and designed in terms of the optical and mechanical parts. A mechanical structure has been designed using theoretical analysis, mathematical modeling, and 3D FEM (Finite Element Method) simulation. The relative aperture displacement according to the base vibration is given using FEM simulation, while the output beam power according to the relative displacement is measured by experiment. The simulated sensor sensitivity of $15.731{\mu}W/G$ and detection range of ${\pm}6.087G$ are given. By using reference signal, the output signal with 0.75% relative error shows a good stability. The proposed vibration sensor structure has the advantages of a simple structure, low cost, and multi-point sensing characteristic. It also has the potential to be made by MEMS (Micro-Electro-Mechanical System) technology.

The Affective/Cognitive Involvement and Satisfaction According to the Usage Motivations of Social Network Services (소셜네트워크 이용동기에 따른 감정적 관여, 인지적 관여의 형성과 만족)

  • Chun, Myung-Hwan
    • Management & Information Systems Review
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    • v.31 no.2
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    • pp.21-39
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    • 2012
  • To examine how usage of social network services(SNS) can affect users' satisfaction through their involvement to SNS. This study first explored the usage motives on the SNS by reviewing previous studies which are from the perspectives of usage and gratification theory. The structural equation modeling(SEM) approach was used to validate the model and Lisrel was used to analyze 306 data which were collected from college students who have SNS using experiences. The results showed that the motives of information seeking and self-expression have no significant influence on affective involvement to SNS and other hypotheses were all accepted. In order to investigate the relationship of usage motives-involvement-satisfaction between different genders, path analysis in male group and female group were done respectively. The results showed that in the case of male group, the motivation of information seeking, entertainment, and self-expression have positive effect on affective involvement, while only the entertainment motive can increase the cognitive involvement. In the case of female group, socializing motive and entertainment motive have positive effect on both affective involvement and cognitive involvement, but the information seeking motive and self-expression motive can not influence the formulation of emotion in SNS.

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Factors Affecting the Mental Health of Adolescents : Mediating Effects of Alcohol Drinking (청소년의 심리건강 영향요인: 음주의 매개효과)

  • Sohn, Minsung;Kim, Mi Sun;Yoon, Ki Chan;Choi, Mankyu
    • The Journal of the Korea Contents Association
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    • v.13 no.2
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    • pp.359-369
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    • 2013
  • In this study, the relationship between social support and adolescent mental health was examined. A primary aim was to investigate how family, school, and friends affect adolescent mental health including depression, stress, and anger issues. This study also intended to investigate the indirect effect of these factors through the mediator, problem drinking. The study used survey data collected from the "2010 The Study on Mental Health of Korean Adolescents" conducted by National Youth Policy Institute, and 942 subjects were selected for this study. The study hypotheses were tested using SEM (Structural Equation Modeling) analysis. Analyses revealed that the appropriate functions and roles of the family members had the effect of promoting mental health of adolescents. Inappropriate functions and roles of the family members induced problem drinking, and this eventually had a negative impact on mental health causing depression, stress, and angel problems. Results also showed that having more friends who drink alcohol or smoke cigarette had no direct effect on the mental health of adolescents; however, there was an indirect effect through the mediator variable, problem drinking. The finding of this study revealed the need and importance of appropriate social support system and environment in order to promote mental health of adolescents.

3D Product digital camera Model on the Web and study about developing 3D shopping mall (Web 상에서 3차원 디지털카메라제품모델과 3차원 쇼핑몰 개발에 관한 연구)

  • 조진희;이규옥
    • Archives of design research
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    • v.14 no.1
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    • pp.63-70
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    • 2001
  • Thanks to the inter-connection of information servers throughout the world based on the internet technology, the new sphere which actual transaction can be made like in the visible market has become conspicuous as the virtual space. The movement to realize the new business through the cyber space has been actively ongoing. In the domestic market, a lot of corporations knowing the needs of internet shopping malls have entered into this e-business but they have not made a big success comparing with internet's potentials. And, it can be attributed to the simple planes and the limitations of information provided by the cyber malls, which means that the needs of better information transfer we apparent Accordingly, in this thesis, the research on the 3-D based products and shopping malls has been made through the inter-complementary composition between the 2-D shopping malls and 3-B ones. This research consists of 3 parts. Firstly, through the research on references and existing data, it presents the analysis on consumer's characteristics and sales limits of the internet shopping mall's products. Secondly, the background of 3-D shopping mall's advent and the virtual reality technology data are put together. Finally, it presents how the development of 3-D based product modeling and shopping malls can increase the consumer's purchase power and furthermore the directions of shopping malls to go.

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Improvement of the Code Classification Structure in Piping Material Management for Petrochemical Plant Projects (석유화학 플랜트의 효율적 배관자재 관리를 위한 코드분류체계 개선)

  • Lee, Jong-Pill;Moon, Yoon-Jae;Lee, Jae-Heon
    • Plant Journal
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    • v.11 no.1
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    • pp.39-49
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    • 2015
  • The objective of this study is to improve the classification structure of commodity code for piping material management which is considered as the fundamental of commodity code and piping material management system. It enhances the efficiency of piping material management directly or indirectly affecting the engineering, procurement and construction in a petrochemical plant projects. To establish an improved code classification structure, this study identifies the problems of former code classification structure in details, as well as the characteristics of other domestic and global EPC company's code classification structures and presents the improved direction considering the recently mega-sized and specialized projects. Accordingly, to efficiently enhance piping material management, the improved code classification structures have been derived from defining suitable code classification structure for specific piping component, adding more standard attribute, expanding the number of code digits and classifying code hierarchy. The results of applying the improved classification structure of commodity code to on-going project have led to reduce the rate of rework from 4.98% to 2.48% for developing purchase description and also have saved working time for executing piping design by 3D modeling from 6 months by two persons to 4 months by a person which is decreased 67% consequently. In addition, the structures of pyramid code management have resulted to accumulation and analysis of the various piping data for other disciplines such as procurement and estimation team which require commodity code information through the company's material control system.

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The Mediating Effect of Ego-Resilience on the Relation between Self-rated Health and Life Satisfaction of the Adolescents (청소년의 주관적 건강수준과 삶의 만족도에서 자아탄력성의 매개효과)

  • Lee, Jin-Pyo
    • Journal of Digital Convergence
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    • v.18 no.8
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    • pp.321-330
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    • 2020
  • This study was conducted to provide the basis for the establishment of various youth policies by analyzing and validating the mediated effects of ego resilience on the impact of adolescents' self-rated health on life satisfaction. The population consisted of a nationally representative sample of adolescents(n=1,979) in high school first grade student who completed the Korean Children and Youth Panel Survey(KCYPS) in 2016. The study analyzed the data by descriptive analysis, t-test, ANOVA, Pearson's correlation coefficients and path modeling, using the SPSS and AMOS program. The result is following; Self-rated health has significant effects of ego-resilience(β=.26, p<.05). Self-rated health(β=.18, p<.05) and ego-resilience(β=.45, p<.05) have shown significant implications for life satisfaction. In addition, ego-resilience have been shown to be partial mediation effect between Self-rated health and life satisfaction. The results revealed that the adolescents who scored high on self-rated health were better the life satisfaction, and ego-resilience partially mediated the relationship between self-rated health and life satisfaction in adolescents. In order to increase the life satisfaction for adolescent, it was confirmed that a multi-dimensional approach is needed to consider the self-rated health as well as self-resilience.