• The Journal of the Korean bone and joint tumor society
• /
• v.10 no.1
• /
• pp.1-12
• /
• 2004

Purpose: The current study was performed to analyze the oncological and functional results, and the patient, the limb and the prosthesis survival of osteosarcoma around the knee in children according to the treatment options. Materials and Methods: From 1982 to 2002, 63 patients with osteosarcoma around the knee underwent surgical treatments before 16 years of age. Surgical treatment options were amputation, endoprosthetic replacement, and implantation of low heat-treated autogenous bone graft after wide resection of tumor. The mean age of patients was 11.5 years (4.4~16), and the mean follow-up period was 6.1 years (2.1~16.8). All patients had neoadjuvant and adjuvant chemotherapy. All endoprosthses were extendible types. Anatomical locations of osteosarcoma were distal femur in 40 patients, and proximal tibia in 23 patients. As regard to Enneking stage, 4 patients had stage $II_A$, 50 patients had stage $II_B$, and 9 patients had stage III tumors. Results: The 5 year survival rate of stage $II_B$ patients was 72.7% in amputation, 83.7% in endoprosthesis, and 100% in low heat-treated autogenous bone graft. The 5 year survival rate of salvaged limb was 84.4% in endoprosthesis, and 80% in low heat-treated autogenous bone graft. The survival rate of prosthesis was 92.7% at 5 years, 67.4% at 10 years in endoprosthesis, and 75% at 5 years in low heat-treated autogenous bone graft. Mean functional outcome scores were 8.7 points in amputation, 20.6 points in endoprosthesis, and 16 points in low heat-treated autogenous bone graft. Distant metastasis occurred 15.8% in amputation, 27% in endoprosthesis and local recurrence occurred 8.1% in endoprosthesis, 14.3% in low heat-treated autogenous bone graft. Major complications happened 26.3% in amputation, 35.1% in endoprosthesis, and 28.6% in low heat-treated autogenous bone graft. Conclusion: Limb salvage procedure had functionally better results than amputation in children with osteosarcoma around the knee. Reconstruction with endoprosthesis after resection of tumor had good results in children as adults. In certain circumstances as too small bone for endoprosthesis or minimal bony destruction or too skeletally immature patient, low heat-treated autogenous bone graft may be a good treatment option. Low heat-treated autogenous bone graft may be considered as not only a substitute for endoprosthesis but also a temporary method before endoprosthesis.

• The Journal of the Korean dental association
• /
• v.25 no.9 s.220
• /
• pp.803-803
• /
• 1987

• Archives of Plastic Surgery
• /
• v.39 no.4
• /
• pp.411-411
• /
• 2012

• The Journal of the Korean dental association
• /
• v.25 no.8 s.219
• /
• pp.705-705
• /
• 1987

• The Journal of the Korean bone and joint tumor society
• /
• v.11 no.2
• /
• pp.204-207
• /
• 2005

Osteosarcoma is mainly developing around the knee joint. But osteosarcoma of the calcaneus is rare. A 20 year old male patient visited our clinic due to persistent pain around the calcaneus. We diagnosed it to osteosarcoma of the calcaneus and treated with below knee amputation and adjuvant chemotherapy. We experienced a case of osteosarcoma of the calcaneus and would like to report it with review of literatures.

• Archives of Reconstructive Microsurgery
• /
• v.22 no.2
• /
• pp.86-89
• /
• 2013

The neuroma is a tumor of nerve tissue that partially or completely severed through incomplete regeneration process. Neuromas that formed in the stump of a limb following amputation is a cause of the stump pain and can make intractable pain. The authors report a rare case of 36-year-old man with neuroma at stump, which has been recurred three times. This patient was treated with end-to-end neurorrhaphy after resecting neuroma. Follow-up at out-patient clinic showed satisfied result.

• Journal of Veterinary Clinics
• /
• v.20 no.2
• /
• pp.259-262
• /
• 2003

A 13-year old male dog with right forelimb lameness, invisible swelling, anorexia and mild depression was referred to Veterinary leaching Hospital, College of Veterinary Medicine, Kyungpook National University. On forelimb radiographic views, periosteal and endosteal proliferation and cortical lysis and extremely aggressive and amorphous periosteal reactions were located along the metaphyseal region of the proximal humerus. Cytologic and histopathologic examinations after amputation showed anaplastic mesenchymal cells that produced osteoid changes, poorly differentiated osteoblast and osteoclast. And also, it included the neoplastic cells with large nucleoli, multiple nucleoli that differ in size and cytoplasm with several clear vacuoles. Based on the physical examination and laboratory, radiolographic, cytologic and histopathologic findings, this case was diagnosed as osteosarcoma of the proximal humerus.

• Archives of Reconstructive Microsurgery
• /
• v.14 no.1
• /
• pp.31-36
• /
• 2005

Purpose: We analyzed the result of the radial forearm island flap for the reconstruction of amputated fingers. Materials and Methods: From March 2001 to February 2004, we assessed two patients who could not be able to receive replantation and six patients who had necrosis of the fingers after replantation. There were six men and two women. The mean age was 42 years. The average duration of follow-up was 26months. Results: All flaps were survived. Two patients needed bone graft. Two patients needed curettage due to osteomyelitis. All patients needed fat reduction procedure. No patients needed amputation of reconstructed digit due to complication. Conclusion: Radial forearm island flap seems useful operation procedure for severely amputated digit or necrotized digit after replantation.

• Proceedings of the KACD Conference
• /
• 2001.11a
• /
• pp.566.1-566
• /
• 2001

The most desirable healing process for endodontic therapy is apical closure by hard tissue such as dentine or cementum. Then, we estimated hard tissue conductivity of tetracalcium phosphate (4CP)/dicalcium phosphate (2CP) compound using mandibular first molars of SD rats. Residual pulp responses to the calcium phosphate compound were examined at several amputation levels of pulp. 2CP was purchased and passed through a $32-\mu\textrm{m}$ sieve. 4CP was obtained from a stoichiometric mixture of 2CP and calcium carbonate (Mol ratio: Ca/P=2.0) by the dry synthetic method at 1, 400(C for 8 hours.(omitted)

• Journal of Korean Foot and Ankle Society
• /
• v.13 no.1
• /
• pp.109-112
• /
• 2009

Calciphylaxis is a rare disease that appear in patients with secondary hyper-parathyroidism or chronic renal failure or that show defect in calcium phosphate metabolism which is characterized by fibrin deposit or calcification of medial wall of vessels causing gradual ischemic skin necrosis. Calciphylaxis is a disease with poor prognosis as skin necrosis can progress rapidly. If left untreated, calciphylaxis will progress to sepsis with high mortality. The treatment is controversial but kidney transplantation or parathyroidectomy is suggested to recover calcium-phosphate metabolism. The authors have experienced calciphylaxis in a patient with chronic renal failure caused by DM nephropathy with characteristic skin lesion and rapid skin necrosis. We describe this case with documentary reviews.