• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.19 no.3 s.31
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• pp.209-214
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• 2006

Allergic conjunctivitis is frequent 90% of allergic reaction of eyes. It is difficult to know the cause, so it is impossible to keep away from the antigens. The purpose of the treatment is just subsiding the symptoms without side effects. We experienced one case of Allergic conjunctivitis treated with oriental medical treatment, acupuncture and herbal medication. 27 year-old male patient had diagnosed Allergic conjunctivitis by western medical doctor. He suffered from eye itching, so he couldn't sleep well. After treatment his itching was subsided and he could sleep well. Therefore, oriental medical treatments could be safe and effective methods.

• Korean Journal of Adult Nursing
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• v.27 no.4
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• pp.438-448
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• 2015

Purpose: The purpose of this study was to identify the effects of using aroma essential oils on allergic symptoms, eosinophils and quality of life related to rhinitis for university students with allergic rhinitis. Methods: A randomized controlled experimental design was used. There were 37 participants in the experimental group, and 30 in the control group. The experimental group applied the essential oils four times a day in the nasal area as well as using inhalation of the oils each night for four weeks. Rhinoconjunctivitis quality of life questionnaire was composed of 28 questions regarding seven areas associated with allergic reactions. The data were analyzed with SPSS/WIN 21.0 program. Results: Rhinitis symptom index, nose itching (p<.001), sneezing (p<.001), watery rhinorrhea (p<.001), and nose congestion (p<.001) all had significant difference for the participants in the treatment group. Further there were significant differences in eosinophils both for measured time and interaction (p<.001). For the quality of life related to rhinitis, the results showed significant difference (p<.001). Conclusion: Using aroma therapy by applying essential oils turned out to be an effective nursing intervention that can be utilized in the easing of allergic symptom and the decrease of eosinophils, causing improvement in the quality of life related to rhinitis.

• Korean Journal of Acupuncture
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• v.28 no.3
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• pp.221-231
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• 2011

Objectives : Kamibojungikgi-tang is one of the most frequently used medical treatment for the allergic rhinitis. The main symptoms of the allergic rhinitis are nasal obstruction, watery rhinorrhea, and sneezing. In this study, we investigated the medical effect of the Kamibojungikgi -tang with intradermal acupuncture treatment on the allergic rhinitis in 10-11 years old children. Methods : For 8 weeks, we administered Kamibojungikgi-tang to 84 patients and treated them with intradermal acupuncture. We checked their serum IgE and examined 10 symptoms of the allergic rhinitis (nasal obstruction, watery rhiorrhea, sneezing, nasal pruritus, hyposmia, quality of life, color of nasal mucosa, edema of nasal mucosa, postnasal drip, and complication). Results : 1. Serum IgE decreased 2.62 point. which showed no significance. 2. Nasal obstruction, watery rhiorrhea, sneezing, nasal pruritus, hyposmia, quality of life, color of nasal mucosa, edema of nasal mucosa, and postnasal drip were improved. (p<0.005) 3. Complication showed no significance. Conclusions : After treatment, we had a lower symptom index scores. Kamibojungikgi-tang with intradermal acupuncture treatment had an effect on the allergic rhinitis.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.20 no.3
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• pp.29-42
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• 2007

Objectives : Allergic rhinitis is an inflammation or irritation of the mucous membranes that in the nose. Common symptoms include sneezing; a stuffy or runny nose; itch eyes, nose and throat; and watery eyes. We aimed to determine therapeutic effect of Onpye-tang by observing changes in blood cells and the nasal mucosal tissue. Methods : Twenty-four Sprague-Dawley rats were divided into three groups: normal, control, and sample group. Allergic rhinitis was induced in the control and sample group by intraperitoneal and intranasal sensitization with 0.l% Ovalbumin solution. Then Onpye-tang was orally administered only to the sample group for 28days, while the rats in the control group was given normal saline. We observed changes in the number of RBC and WBC; changes of neutrophils, lymphocyte, monocyte, and eosinophil proportions; total IgE level and AST & ALT change; also, changes in the nasal mucosal tissue. We used Student T-test statistically(p<0.05). Results : Onpye-tang showed significantly decreased IgE level on the serum of the rat model. Onpye-tang showed significantly decreased eosinophil level on the blood of the rat model. Onpye-tang inhibited the inflammatory reaction on the nasal mucosal tissue, according to nasal mucosal biopsy. Onpye-tang showed an inhibitory effect on the process of allergic rhinitis, according to IgE level, Eosinophil level, nasal mucosal biopsy. Onpye-tang had no hepatoxicity, according to AST and ALT on the serum. Conclusion : According to the above results, it is considered that Onpye-tang has an inhibitory effect on the process of allergic rhinitis and it can be used in relieving symptoms of allergic rhinitis.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.18 no.3
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• pp.55-65
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• 2005

Objectives: Allergic rhinitis is an inflammation or irritation of the mucous membranes that line the nose. Common symptoms include sneezing; a stuffy or runny nose; itchy eyes, nose and throat; and watery eyes. We aimed to determine therapeutic effects of Gudambope-tang by observing changes in blood cells and the nasal mucosal tissue. Methods: Fifteen Spraque-Dawley rats were divided into three groups: normal, control, and sample group. Allergic rhinitis was induced in the control and sample group by intraperitoneal and intranasal sensitization with 0.1% ovalbumin solution. Then Gudambope-tang was orally administered only to the sample group for 28days, while the rats in the control group was given normal saline. We observed changes in the number of RBC and WBC; changes of neutrophil, Iymphocyte and monocyte proportions; total IgE level and AST & ALT changes; also, changes in the nasal mucosal tissue. We used ANOVA test statistically(p<0.05). Results: 1. Gudambope-tang showed an inhibitory effect on the process of allergic rhinitis. 2. Gudambope-tang inhibited the inflammatory reaction on the nasal mucosal tissue. 3. Gudambope-tang had no hepatoxicity. Conclusions: According to the above results. it is considered that Gudambope-tang has an inhibitory effect on the process of allergic rhinitis and it can be used in relieving symptoms of allergic rhinitis.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.10 no.1
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• pp.332-339
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• 1997

This study evaluates the effect of G.G.(桂枝湯 加味方) in patients with allergic rhinitis which deteriorates with cold, who visited Oriental hospital of Kyungwon University from march to september in 1996 and found the symptoms were inproved significantly. 1. G.G.(桂枝湯 加味方) was prescribed for the patients with sneezing and more than $80\%$ of patients showed improvement 2. Oriental treatments of allergic rhinitis have been showed relative good results and more constructive study and clinical report are necessary.

• The Korea Journal of Herbology
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• v.27 no.5
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• pp.85-91
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• 2012

Objectives : In this study, we investigated the effect of Saposhnikoviae Radix on allergic responses in ovalbumin(OVA)-induced Allergic rhinitis(AR) mice. Methods : BALB/c mice were orally administrated with Saposhnikoviae Radix water extract (SRW, 50 mg/kg) or anti-histamine drug, Ketotifen (10 mg/kg) as a reference drug, followed by sensitization and challenge of OVA. Mice were measured clinical symptoms and the serum levels of histamine, IgE, IL-4, and IFN-${\gamma}$, and observed histopathological changes of nasal mucosa H&E staining. Results : SRW significantly decreased rubs and the serum levels of histamine, IgE, and IL-4, and then increased the serum levels of IFN-${\gamma}$ in OVA-induced AR mice, and inhibited histopathological changes of nasal mucosa with inflammation and the eosinophils infilteration. Conclusions : These data suggest that SRW has anti-allergic effect through the inhibitory property of Saposhnikoviae Radix against allergic responses in allergic rhinitis.

• Korean journal of aerospace and environmental medicine
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• v.30 no.2
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• pp.66-69
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• 2020

Since allergic rhinitis is a disease with a very high prevalence, it is common to find patients with allergic rhinitis among aviation workers. However, they are so afraid that the report of rhinitis will have a negative effect on the evaluation of one's work suitability. Therefore, aviation medical examiners (AMEs) must be able to accurately understand the nature of allergic rhinitis, and confidently explain that appropriate treatment of rhinitis has a positive effect on their performance. In the treatment of allergic rhinitis, there are some medications that may cause drowsiness, which may impair the accuracy and safety of the aviation service. Therefore, AMEs should accurately know safe drugs that do not cause drowsiness and prescribe them to patients. In addition, it is necessary to know exactly whether air workers may receive the latest treatments for allergic rhinitis, such as surgical treatment and immunotherapy, and be able to recommend these treatments appropriately. Therefore, in this paper, we first briefly describe the pathophysiology, genetics, causative antigen, symptoms, diagnosis, and treatment of allergic rhinitis. We also aimed to discuss safe medication and other treatment modalities for allergic rhinitis.

• Journal of Korean Public Health Nursing
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• v.12 no.2
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• pp.136-148
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• 1998

This study was conducted to provide basic knowledge of effective environmental control of patients with allergic rhinitis during the period of July to December 1995. The subjects were consisted of 29 patients with allergic rhinitis. Each patient of nasal symptom scores assessed and dust samples drowned from their bedrooms twice for 1 month interval. The data. 58 samples were analyzed by using ANOVA. t-test and stepwise multiple regression. The results were as follows 1. Out of a total 52 dust samples $(89.7\%)$ were isolated house mites. Total 815mites/0.5gm dust were collected and identified the most prevalent house mites was Pyroglypidae mite with $81.1\%$ 2. The amount of house dust mites in the group of bedding laundry with hot water was significantly lower than that those of with cold water. 3. The nasal symptoms of the patients in the group of bedding laundry with hot water was significantly less than that those of with cold water. and also those of using large size bedroom was significantly lower than that those of using small size one. The nasal symptoms of the patients was closely associated with the washing water temperature. bedroom size. bedroom temperature. type of bedclothes, and frequency of cleanig room.

• Biomedical Science Letters
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• v.26 no.3
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• pp.192-200
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• 2020

Natural products have received revived interest via traditional remedies or alternative medicine used for the treatment of various diseases. Zanthoxylum piperitum (ZP) has been utilized in traditional medicine for various medicinal purposes. The present study was conducted to evaluate whether ZP modulates allergic inflammation both in vivo and in vitro. We examined the pharmacological effects of ZP on 2, 4-dinitrochlorobenzene (DNCB)-induced atopic dermatitis (AD) symptoms in mice. Additionally, in order to clarify the anti-inflammatory mechanisms of ZP, we elucidate the effect of ZP on the expression levels of inflammatory cytokines and nuclear factor-κB (NF-κB) in phorbol 12-myristate 13-acetate plus calcium ionophore A23187 (PMACI)-stimulated human mast cells (HMC-1). The results demonstrated that ZP attenuated AD clinical symptoms such as erythema, edema and dryness as well as histamine and IgE serum levels in DNCB-induced AD model mice. Additionally, ZP suppressed the expression of inflammatory cytokines and activation of NF-κB in AD-like skin lesions and stimulated HMC-1. These results provide experimental evidence that ZP may be useful candidate for treating allergic inflammation including AD.