• Title/Summary/Keyword: allergens

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OBSERVATION ON PATCH TEST USING A FEW DENTAL MEDICAMENTS BASED ON NURSING ASPECT (치과용 약제 접촉이 인체피부조직에 미치는 영향에 관한 간호학적 고찰)

  • Han, Song-Ja
    • The Journal of the Korean dental association
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    • v.16 no.12 s.115
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    • pp.941-944
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    • 1978
  • The author studied skin reactions and their incidences among 100 dental students and dental nurses to 2% Lidocaine HC1, 3% H₂O₂, Euginol, 5% Sodium Hypochlorite, Dycal and Adhesive plaster by means of Patch test. Following are the results of the study. 1. Eighty six cases out of 100 revealed slight response to 1 or 2 allergens. 2. 2% Lidocaine HC1 showed 1 case, 3% H₂O₂cases, Euginol 2 cases, 5% Sodium Hypochlorite 74 cases, Dycal 1 case Adhesive plaster 8 cases. 3. 5% Sodium Hypochlorite was the most influential to skin. 32 cases showed grade 1+, 20 cases showed grade 2++, 16 cases showed grade 3+++, 6 cases showed grade 4++++,

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Parthenolide Inhibits Ovalbumin-Induced cyclooxygenase-2 and Inducible Nitric Oxide Synthase Expression

  • Youn, Hyung-Sun
    • Biomedical Science Letters
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    • v.18 no.3
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    • pp.319-323
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    • 2012
  • In recent years, egg allergy has been raised as the most prevalent food hypersensitivity in the pediatric population. One of the major egg allergens is ovalbumin (OVA) which is the major protein in egg white, comprising 54% of its total protein content. Parthenolide isolated from Tanacetum partheniumb has been used to treat many chronic diseases for many years. In the present report, we present biochemical evidence that parthenolide inhibits the nuclear factor-${\kappa}B$ (NF-${\kappa}B$) activation induced by OVA. Parthenolide also inhibits OVA-induced cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase (iNOS) expression. These data suggest new approaches for the efficient alleviation of the allergic symptoms.

Identification of protease-resistant proteins from allergenic nuts using two-dimensional gel electrophoresis and mass spectrometry

  • Santos, Ilyn L.;Lee, Ju-Young;Youm, Yujin;Lim, Jinkyu
    • Current Research on Agriculture and Life Sciences
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    • v.31 no.2
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    • pp.108-112
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    • 2013
  • Nuts are one of the most common sources of allergies in individuals of all ages. In order for a particular protein to render an allergic reaction, it must resist proteolytic digestion by intestinal enzymes. In this study, three well-known allergenic nuts, almonds, cashew nuts, and peanuts, were used as samples, and enzyme digestion with Bacillus protease and porcine pepsin was tested. A proteomic approach using two-dimensional gel electrophoresis and an MS/MS analysis was applied to visualize and identify the proteins that were resistant to enzyme digestion. Among the 150 protein spots tested, 42 proteins were assigned functions. Due to the lack of genomic databases, 41% of the identified proteins were grouped as hypothetical. However, 12% of them were well-known allergens, including AraH. The remainder were grouped as storage, enzymes, and binding proteins.

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System Architecture of Atopic Dermatitis Adjuvant for Children Using Wireless Sensor

  • Balitana, Maricel O.;Kim, Seok-Soo
    • International Journal of Contents
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    • v.4 no.2
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    • pp.1-6
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    • 2008
  • Pre schools with state of the art facilities that would provide not just academic excellence but also ensure the safety and provide efficient healthcare to their pupils relative to Atopic Dermatitis with Asthma is the main objective of this research One of the most promising applications of sensor networks is for human healthcare monitoring. Due to recent technological advances in sensor, low power microelectronics and miniaturization, and wireless networking enable the design and proliferation of this wireless sensor networks capable of autonomously monitoring and controlling environments. Thus, this research presents the utilization of such microelectronic sensor and plots the hardware and software architecture of a wireless sensor network system with real-time pupil monitoring that integrates vital sign sensors, location sensor and allergen sensor. This proposed architecture for wearable sensors can be used as active tags which can track pupil's location within the school's premises, identify possible atopic dermatitis with asthma allergens, it would monitor and generate a health status report of the pupil.

Sarcoptic Mange and latrogenic Hyperadrenocorticoidism in a Dog Undergoing Hyposensitisation for Atopy based on RAST Testing (방사선 알레르기 흡착 시험법(Radioallergosorbent testing, RAST)에 기반을 둔 아토피에 대한 저감작을 경험 중인 개에서의 천공개선충과 임상수의사에 의해 야기되는 고부신피질양증)

  • Burton Greg
    • Journal of the korean veterinary medical association
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    • v.38 no.6
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    • pp.549-558
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    • 2002
  • 3.5살짜리 래브라도 리트리버(Labrador Retriever)는 매일 처방되는 피질스테로이드제에 무반응으로 비계절적, 심한 소양증을 2년간 앓고 있는 병력을 갖고 있었다. 공기유래 알레르겐(알러젠; Allergens)들에 대한 시험관내 RAST1(Radioallergosorbent testing; 방사선 알레르기 흡착 시험법)에 양성으로 나타난 것을 기초로 한 면역요법(Immunotherapy)을 18개월 동안 시행했으나 성공적이지 않았다. 부신피질호르몬(Adrenocorticotropic Hormone, ACTH)자극 시험법은 이것이 본래 임상수의사에 의해 발생(Iatrogenic)된 것임을 예시하여준다. 피부 찰과물(Skin scrapings)을 검사한 결과 개 천공개선충(Sarcoptic mange)이라는 진단이 내려졌다. 이버맥틴(Ivermectin)치료효과와 피질스테로이드(Corticosteroid)의 투약중지에 대한 반응이 극적으로 나타났다. 10개월 추적기간(10-month follow-up period)동안에 이 질병은 재발되지 않았다. 이것은 비록 계절적인 알레르겐을 배제하기 위해 긴 기간동안 추적이 필요하였으나 개 천공개선충이 오히려 피질스테로이드요법에 대한 2차적인 것보다는 1차적인 질병이라는 것을 말해준다. 아토피의 진단을 위해 혈청학적 시험법의 이용이 논의되었다.

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항알러지와 건강 기능성식품에 의한 식품 알러지 개선방안

  • Im, Byeong-U;Kim, Ju-Yeong
    • Bulletin of Food Technology
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    • v.15 no.4
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    • pp.29-35
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    • 2002
  • To prevent the incidence of type food allergies, removal of food allergens by excluding all foodstuffs containing the allergen(s) or disruption of allergen(s) using proteases has been employed. Though allergen- specific digestion with a protease worked well in the preparation of low allergenic goods, it is often difficult to destroy allergenicity without adversely affecting the nutritive value, taste and rheological properties of foods. In the present study, we represented that herbs component contained both allergy- enhancing and inhibiting factors, in addition to llergens. We also reported that herbal component such as epigallocatechingallate (EGCG) and epicatechingallate (ECG) is possible to be allergy- inhibiting factors, but the exact mechanism by which they alleviate allergic response is left to be clarifying. Document of allergy enhancing factors and enrichment of allergy inhibiting factors may provide a new approach to diminish allergenicity of various foodstufffs. Clarification of the allergic reaction modifying mechanism of food components and optimization of the intake of allergy modifying factor are necessary for decrement of allergenicity of conventional food and prevention of incidents of allergic response

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AN EXPERIMENTAL STUDY ON SKIN REACTION TO A FEW DENTAL MEDICAMENTS (수종 치과치료약제의 피부반응에 관한 실험적 연구)

  • Gang, Myeong-Hui
    • The Journal of the Korean dental association
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    • v.13 no.2
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    • pp.133-136
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    • 1975
  • The autor studied skin reactions and their incidences among 130 dental students and dentists to 2% Iidocaine HCI, 2% procaine HCI, direct resin, plaster of paris, zinc oxide-eugenol cement, and adhesive plaster by Patch test. The results of the studies are as follows: 1. Eighteen cases out of 130 revealed slight positive reaction toa 1 or 2 allergens. 2. Lidocaine HCL showed 1 case, procaine HCL 4 cases, direct resin 4 cases, Z.O.E. cement 1 case, adhesive plaster 13 case, and plaster of paris showed none. 3. Two delayed reaction were detected after 48 hours, one of which reacted both lidocaine HCL and direct resin, and the other one was a case of adhesive plaster.

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Isoliquiritigenin Inhibits Ovalbumin-induced Cyclooxygenase-2 and Inducible Nitric Oxide Synthase Expression

  • Lim, Se Jin;Youn, Hyung-Sun
    • Biomedical Science Letters
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    • v.19 no.3
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    • pp.270-274
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    • 2013
  • Egg allergy has been raised as the most prevalent food hypersensitivity in children. Ovalbumin (OVA), which is one of the major egg allergens, is the major protein in egg white. Isoliquiritigenin (ILG) is an active component present in licorice and has been used to treat many chronic diseases for many years. In this study, we present biochemical evidence that ILG inhibits OVA-induced nuclear factor-${\kappa}B$ (NF-${\kappa}B$) activation. ILG also inhibits OVA-induced cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase (iNOS) expression. These data suggest that ILG has anti-allergy effects.