• 대한간호학회지
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• 제49권6호
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• pp.690-700
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• 2019

Purpose: The purpose of this study was to examine the awareness of alcohol use during pregnancy and factors influencing the intention to abstain from alcohol during pregnancy by drinking levels. Methods: Utilizing a comparative descriptive design, a total of 359 female college students were recruited. Measurements were Theory of Planned Behavior (TPB) variables related awareness of alcohol use during pregnancy, Korean Version of the Alcohol Use Disorders Identification Test, knowledge about alcohol use during pregnancy, and socio-demographic factors. Main variables were compared by drinking levels. The factors influencing the intention to abstain from alcohol during pregnancy were identified using hierarchical regression analysis. Results: Non-problematic alcohol behavior group (n=185) had higher the intention to abstain from alcohol during pregnancy than problematic alcohol behavior group (n=174) (t=3.13, p=.002). The significant TPB variables influencing the intention to abstain from alcohol during pregnancy were that attitudes (β =-.44, p<.001), subjective norms (β =.14, p=.026), and perceived behavior control (β =.19, p=.002) in non-problematic alcohol behavior group, whereas the corresponding variables in the problematic alcohol behavior group were attitudes (β =-.51, p<.001) and subjective norms (β =.21, p=.006). Conclusion: It is necessary to increase the intention to abstain from alcohol during pregnancy for the female college students having problematic alcohol behavior. The following strategies are recommended for them; decreasing acceptable attitudes toward alcohol use during pregnancy and reinforcing the influence of social pressure toward to abstain from alcohol during pregnancy.

• 한국생물공학회:학술대회논문집
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• 한국생물공학회 2003년도 생물공학의 동향(XIII)
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• pp.214-218
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• 2003

Alcohol consumption causes numerous consequences on the health of the human body. Heavy drinking on a daily base has caused liver diseases. Furthermore, some products such as acetaldehyde produced from alcohol metabolism are more toxic than alcohol itself. This study was carried out to evaluate the role of Lactobacillus casei on alcohol metabolism, especially, the removal of the toxic effect of alcohol. The maximum alcohol dehydrogenase (ADH) and acetaldehyde dehydrogenase (ALDH) activities from L. casei were observed at 4 hr of culture. L. casei was confirmed to produce the ADH and ALDH by the SDS-PAGE. From in vivo test using SD rats with 22% alcoholic drink, blood alcohol concentration (BAC), glutamic oxaloacetic transaminase (GOT) and glutamic pyruvic transaminase (GPT) of the rats feeding the medium containing L. casei were lower than those of the rats feeding the medium containing an alcoholic drink only This demonstrates that the ADH and ALDH produced by L. casei have virtual functions to detoxicate the alcohol in vivo and the fermentation broth of L. casei can be used as an alcohol detoxification drink.

• Journal of Trauma and Injury
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• 제22권2호
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• pp.233-241
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• 2009

Purpose: Alcohol is a major risk factor for injuries, but little is known about the relationship between chronic drinking pattern and injuries. The purpose of this study was to evaluate the incidence of alcohol-related injuries and the differences in the characteristics of the injuries between Alcohol Use Disorder Identification Test (AUDIT) categories. Methods: Among a representative sample of the third Korea National Health and Nutrition Examination Survey. 7,697 adults answered questions about injuries, drinking patterns, and socioeconomic status. Incidences of alcohol-related injuries and of non-alcohol-related injuries were calculated, and the relative ratio of injuries between AUDIT categories was analyzed. Results: The incidences of all injuries and alcohol-related injuries were 69.2 and 6.8 per 1000 person-year. After adjustment, the incidences of non-alcohol-related injuries showed no differences between AUDIT categories. But the adjusted relative ratios (RRs) of alcohol-related injuries were 3.73 (95% CI: 1.54~8.99) and 7.70 (95% CI: 3.61~16.44) for risk drinkers and for alcohol-dependent drinkers respectively. No specific body part could be identified as being frequently injured in cases of risk drinkers and alcohol-dependent drinkers. In contrast, the adjusted RRs of fractures, bruises, and open wounds were 1.76 (95% CI: 1.03~3.02), 1.73 (95% CI: 1.15~2.61), and 1.85 (95% CI: 1.17~2.93) for alcohol-dependent drinkers. Assaults occurred 4.66 times more frequently in alcohol-dependent drinkers. Conclusion: Alcohol-related injuries occur more frequently as the person becomes more dependent on alcohol. Fractures, Bruises, open wounds, and assaults occur more frequently in alcohol-dependent drinker. This study suggests that efforts should be carried out in the ED to screen and treat alcohol-use disorders associated with patients injured after drinking.

• 한국치위생학회지
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• 제15권5호
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• pp.889-898
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• 2015

Objectives: The purpose of the study is to investigate the oral health-related quality of life (OHIP-14) according to smoking in the male workers in Gunsan. Methods: A self-reported questionnaire was completed by 460 male workers in Gunsan from April 13 to 30, 2015. Among 460 workers, smokers were 205 and nonsmokers were 255. The questionnaire included three questions of general characteristics of the subjects, four questions of subjective oral health, fourteen questions of OHIP, ten questions of sobriety test (AUDIT), and eight questions of smoking (Fagerstrom Test for Nicotine Dependence, FTND). Data were analyzed by frequency analysis, t-test, ANOVA, Pearson's correlation, and multiple regression analysis using IBM SPSS(Statistical Package for the Social Science) for Windows 20.0 program. Results: In the nonsmokers, there was a negative correlation between the alcohol consumption, dental health condition, tooth pain, gum bleeding, and halitosis. The higher OHIP in the smokers had the negative correlation with nicotine dependence, alcohol consumption, tooth pain, gum bleeding, and halitosis. In order to improve OHIP, smokers are encouraged to manage gum bleeding, and non-smokers to halitosis. Conclusions: In order to improve OHIP, cessation of smoking and alcohol consumption is very important and it can lead to improve the quality of life in the workers.

• 디지털융복합연구
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• 제11권3호
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• pp.327-335
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• 2013

연구의 목적은 일부 도시지역 주민의 음주실태와 음주문제 관련 요인을 파악하기 위한 것이다. 자료수집 기간은 2008년 10월부터 2009년 9월까지였고, 조사 대상은 음주의 경험이 있는 20세 이상 성인 359명 이었으며 연구도구는 alcohol use disorder identification test(AUDIT), 음주관련 요인이었다. 자료분석은 SPSS 18.0 프로그램을 사용하여 서술적 통계, t-test, ANOVA, hierarchical multiple regression으로 분석하였다. 분석결과는 대상자의 35.7%가 문제음주자로 나타났다. 남성, 고등학교 졸업 이전에 처음 술을 마신 경우, 영구임대 및 무허가 등에서 주거하는 경우, 음주운전의 경험이 있는 경우 음주문제에 영향력을 미치는 것으로 나타났다. 이상의 결과를 통하여 음주문제 예방을 위한 조기교육과 고위험군에 대한 정기적인 관리가 중요하며 이상의 결과를 반영한 교육 프로그램 개발 및 시행이 필요하다고 사료된다.

• 한국학교보건학회지
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• 제19권2호
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• pp.117-125
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• 2006

Purpose : The purpose of this study is to test the effect of the web-b ased alcohol preventive education for ndicate the model of alcohol preventive education for students spreading al over the family and the comunity.Methods : This study was performed on the 1 public and 1 private eleme ntary school students who are the six grade in Seongdong-gu, Seoul. The number of experimental gr oup was 117 and control group's number was 131, totaled 248. eeks. The pre- and the post-test for web-based alcohol preventive education were tested about knowle dge and attitude toward drinking by questionnaire. The data analysis was done using SPS/Win 12.0 p rogram.Results：The results of this study are as follows;1. Compared with control group, experimental group which was educated the web-based alcohol preventive icant diference in the knowledge toward drinking.2. Compared with control group, also the experimental group w as improved with significant diference in attitude toward drinking after the education.3. In control group, female students' knowledge of drinking w as more increased than male students. And the he group which experienced drinking.Conclusions : The web-based alcohol preventi ve education is worth as a int ervention to get positive influence for the health education. Especially in female studen ts who didn't met with drinking, early education for alcohol prevention is very important. Therefore i t will be helpful that coperate with district ofice ithin the comunity for becoming established the controled drinking pattern.

• 한국콘텐츠학회논문지
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• 제16권7호
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• pp.552-565
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• 2016

본 연구는 물질적 어려움과 음주의 관계에서 자아존중감과 가족갈등 요인의 구조적 관계를 검증하는데 목적이 있다. 한국복지패널 최신 3개년도(2012-2014) 자료를 사용하여 가구균등화 소득의 중위소득 60%를 기준으로 저소득가구를 선정하였고, 이중 단독가구를 제외한 960명의 가구주 자료를 분석에 활용하였다. 주요 변수는 물질적 어려움, 음주행위, 자아존중감, 가족갈등이고, 이 변수들 사이의 구조적 관계를 검증하기 위해 경로분석을 사용하였다. 물질적 어려움은 음주에 직접효과를 갖지 않았지만, 가족갈등과 자아존중감을 매개로 하는 간접효과를 보여주었다. 즉, 물질적 어려움을 경험하는 것은 부정적 가족갈등 대처방법, 낮은 자아존중감과 유의미한 관계를 보여주었다. 그리고 긍정적 가족갈등 대처방법과 낮은 자아존중감은 낮은 음주행위와 유의미한 관계를 보여주었다. 이러한 결과는 저소득층이 경험하는 물질적 어려움, 가족갈등, 자아존중감이 문제음주의 결과로 이어질 가능성을 보여주고 있어 이에 대한 실천적 정책적 대응이 필요함을 시사한다.

• Journal of Preventive Medicine and Public Health
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• 제37권3호
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• pp.232-237
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• 2004

Objectives : The study was designed to test if alcohol use and alcohol-related problems among adolescent females are related to their parents' level of alcohol problems. Methods : In 2001, a stratified sample of 2077 adolescent females, grades 10-11, from twelve female-only high schools located in a large metropolitan city in the Republic of Korea completed a questionnaire about alcohol use, parental attention, and parental alcohol consumption, and other risk and protective factors. Data were analyzed with chi-square and regression analyses. Results : Nearly 63% of the student drinkers had experienced at least one to two alcohol-related problems in their lives. Two-thirds of all 2077 students indicated that at least one of their parents had an alcohol-related problem and that approximately 29% had experienced several problems. Results of random effects ordinal logistic regression analyses suggest a dose-response relationship between parental and youth alcohol-related problems. Youth who report having parents with some and many alcohol problems were 30% (Odds Ratios [OR] = 1.30; 95% Confidence Interval [CI] = 1.10 - 1.53) and 55% (OR = 1.55; 95%CI = 1.23 - 1.95) more likely to experience alcohol-related problems than youth whose parents do not have alcohol problems, respectively, after statistically adjusting for important covariates. Conclusions : This study presents evidence that alcohol-related problems among adolescent female students is highly prevalent. Also, the study findings reveal a high percentage of parents with alcohol problems, as reported by students. This study presents evidence of what might be a hidden problem among adults and youths in the Republic of Korea that merits serious attention.

• 한국방사선학회논문지
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• 제16권5호
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• pp.575-583
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• 2022

AUDIT(Alcohol Use Disorders Identification Test)에서 정상 음주자, 위험 음주자 및 알코올 사용 장애자로 분류하여 뇌 백질 영역의 ROI(Region Of Interest)에 대한 FA 측정값을 분석하였다. TBSS(Tract-Based Spatial Statics) 도구를 사용하여 ROI의 FA 값을 추출하였다. TBSS라는 도구는 뇌 회백질보다는 백질에 대한 FA값과 MD 값의 민감도가 더 높고 뇌 신경섬유의 비등방도를 정량적으로 도출해 낼 수 있는 장점이 있고 백질에 더 특화된 프로그램이라 할 수 있다. 특히 양쪽 맥락총 평균 차이가 높았고 정상 음주자에서는 FA의 평균값이 0.2831과 0.2872로 나타났으며, 알코올 사용 장애자의 경우 0.1972와 0.1936로 나타났다. 즉, AUDIT 척도에서 점수가 높을수록 뇌 백질의 계측한 모든 ROI 영역에서 FA 값이 더 낮게 측정되는 것을 알 수 있었으며 뇌 백질에 신경 섬유로의 손상에 대한 미세구조 변화를 확인할 수 있었다. AUDIT 척도를 사용하여 DTI의 FA 값에 대한 지침을 제시할 수 있으며 혈액학적 인자의 가이드인 처럼 FA 값을 산정한다면 알코올 사용 장애자의 선별 및 진단에 유용한 검사법이라 사료 된다.

• 고려인삼학회:학술대회논문집
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• 고려인삼학회 1988년도 학술대회지
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• pp.25-27
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• 1988

건강한 성인남자 14명을 대상으로 하여 혈중 알콜해독에 미치는 인삼의 효과 관찰 실험을 실시하였다. 술과 인삼을 동시에 마시는 시험군과 술만 마시는 대조군을 설정하여, 술을 마신후 40분이 경과하였을 때 혈중알콜농도를 측정하였다. 술 (70g/65kg 체중)과 동시에 인삼 (3g/65kg체중)을 먹었을 때의 혈중알콜농도 ($0.11\%$)는 대조군의 혈중알콜농도 ($0.18\%$)의 약 $6.5\%$이었고, 또 혈중알콜농도를 각 개인별로 비교해보면 실험대상자 14명중 인삼과 술을 동시에 마셨을때의 혈중 알콜농도가 술만 마셨을 때의 혈중 알콜농도의 $65\%{\~}49\%$에 불과한 사람이 10명이나 되었다. 인삼의 알콜배출속도에 미치는 영향을 관찰하기 위한 방사능이 표시된 알콜을 실험동물에 투여한 후 알콜의 대사물인 $^{14}CO_2$가 호흡을 통하여 배출되는 량을 측정비교 하였다. 알콜 투여후 2-7시간 사이의 $^{14}CO_2$ 배출속도는 알콜의 대사 및 배출속도를 증가시켜 알콜해독을 촉진한다는 것을 설명해주고 있다.